JP6538682B2 - Cgrpアゴニストペプチド - Google Patents

Cgrpアゴニストペプチド Download PDF

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Publication number
JP6538682B2
JP6538682B2 JP2016531836A JP2016531836A JP6538682B2 JP 6538682 B2 JP6538682 B2 JP 6538682B2 JP 2016531836 A JP2016531836 A JP 2016531836A JP 2016531836 A JP2016531836 A JP 2016531836A JP 6538682 B2 JP6538682 B2 JP 6538682B2
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Prior art keywords
cgrp
agonist
peptide
seq
related peptide
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JP2016531836A
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English (en)
Japanese (ja)
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JP2016528231A5 (https=
JP2016528231A (ja
Inventor
ソアレス、クリストファー、ジェイ.
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ソアレス クリストファー ジェイ.
ソアレス クリストファー ジェイ.
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Publication of JP2016528231A5 publication Critical patent/JP2016528231A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57527Calcitonin gene related peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2016531836A 2013-07-30 2014-07-29 Cgrpアゴニストペプチド Active JP6538682B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361860244P 2013-07-30 2013-07-30
US61/860,244 2013-07-30
PCT/US2014/048724 WO2015017455A1 (en) 2013-07-30 2014-07-29 Cgrp agonist peptides

Publications (3)

Publication Number Publication Date
JP2016528231A JP2016528231A (ja) 2016-09-15
JP2016528231A5 JP2016528231A5 (https=) 2017-09-07
JP6538682B2 true JP6538682B2 (ja) 2019-07-03

Family

ID=51355665

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016531836A Active JP6538682B2 (ja) 2013-07-30 2014-07-29 Cgrpアゴニストペプチド

Country Status (4)

Country Link
US (1) US9951115B2 (https=)
EP (1) EP3027644B1 (https=)
JP (1) JP6538682B2 (https=)
WO (1) WO2015017455A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10464983B2 (en) 2015-05-13 2019-11-05 The Board Of Regents Of The University Of Oklahoma Variants of adrenomedullin and calcitonin gene-related peptide and methods of use
EP3366286A1 (en) * 2017-02-22 2018-08-29 Johannes Keller Compounds for treating sepsis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021665A1 (en) * 1993-03-24 1994-09-29 Amylin Pharmaceuticals, Inc. Cloned receptors and methods for screening
RU2385878C2 (ru) * 2004-02-11 2010-04-10 Амилин Фармасьютикалз, Инк. Пептид, обладающий свойствами амилина (варианты), и его применение (варианты)
EP2286840A3 (en) 2004-11-01 2013-09-04 Amylin Pharmaceuticals, LLC Treatment of obesity and related diseases
EP2258382A3 (en) * 2005-03-31 2014-05-14 Amylin Pharmaceuticals, LLC Amylin and amylin agonists for treating psychiatric diseases and disorders
WO2007055743A2 (en) 2005-11-01 2007-05-18 Amylin Pharmaceuticals, Inc. Treatment of obesity and related disorders
KR20100098628A (ko) * 2007-11-14 2010-09-08 아밀린 파마슈티칼스, 인크. 비만 및 비만 관련 질환 및 장애의 치료 방법
US8748375B2 (en) * 2009-03-17 2014-06-10 Amylin Pharmaceuticals, Llc Methods for affecting body composition using amylin agonists
US20140249076A1 (en) * 2011-10-18 2014-09-04 Astrazeneca Pharmaceuticals Lp Amylin-calcitonin chimeric peptides conjugated to duration enhancing moieties
CA2861392C (en) * 2012-01-26 2021-08-17 Christopher J. Soares Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use

Also Published As

Publication number Publication date
JP2016528231A (ja) 2016-09-15
EP3027644A1 (en) 2016-06-08
US9951115B2 (en) 2018-04-24
WO2015017455A1 (en) 2015-02-05
EP3027644B1 (en) 2019-08-21
US20160207975A1 (en) 2016-07-21

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