JP6408219B2 - Th1特性と細胞溶解性を発現する細胞 - Google Patents

Th1特性と細胞溶解性を発現する細胞 Download PDF

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JP6408219B2
JP6408219B2 JP2013526060A JP2013526060A JP6408219B2 JP 6408219 B2 JP6408219 B2 JP 6408219B2 JP 2013526060 A JP2013526060 A JP 2013526060A JP 2013526060 A JP2013526060 A JP 2013526060A JP 6408219 B2 JP6408219 B2 JP 6408219B2
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cells
killer
producing
activated
tumor
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JP2013536232A5 (de
JP2013536232A (ja
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マイケル ハー−ノイ
マイケル ハー−ノイ
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イミュノバティブ セラピーズ,リミテッド
イミュノバティブ セラピーズ,リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5158Antigen-pulsed cells, e.g. T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/51B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/515CD3, T-cell receptor complex

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
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  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Wood Science & Technology (AREA)
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  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
JP2013526060A 2010-08-20 2011-08-22 Th1特性と細胞溶解性を発現する細胞 Active JP6408219B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40188110P 2010-08-20 2010-08-20
US61/401,881 2010-08-20
US201161495055P 2011-06-09 2011-06-09
US61/495,055 2011-06-09
PCT/US2011/048578 WO2012024666A2 (en) 2010-08-20 2011-08-22 Cells expressing th1 characteristics and cytolytic properties

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016235386A Division JP6525946B2 (ja) 2010-08-20 2016-12-02 Th1特性と細胞溶解性を発現する細胞

Publications (3)

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JP2013536232A JP2013536232A (ja) 2013-09-19
JP2013536232A5 JP2013536232A5 (de) 2014-10-16
JP6408219B2 true JP6408219B2 (ja) 2018-10-17

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JP2013526060A Active JP6408219B2 (ja) 2010-08-20 2011-08-22 Th1特性と細胞溶解性を発現する細胞
JP2016235386A Active JP6525946B2 (ja) 2010-08-20 2016-12-02 Th1特性と細胞溶解性を発現する細胞

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Country Status (18)

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US (3) US20120045423A1 (de)
EP (1) EP2606125B1 (de)
JP (2) JP6408219B2 (de)
KR (1) KR101900807B1 (de)
CN (2) CN108245673A (de)
AU (1) AU2011291477B2 (de)
BR (1) BR112013003989B1 (de)
CA (1) CA2808873C (de)
DK (1) DK2606125T3 (de)
ES (1) ES2660577T3 (de)
HU (1) HUE036094T2 (de)
IL (1) IL224813B (de)
NO (1) NO2606125T3 (de)
PL (1) PL2606125T3 (de)
PT (1) PT2606125T (de)
SG (2) SG187846A1 (de)
TR (1) TR201802334T4 (de)
WO (1) WO2012024666A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2606125T3 (de) * 2010-08-20 2018-04-21
KR101697473B1 (ko) 2014-11-26 2017-01-18 주식회사 녹십자랩셀 T 세포를 이용한 자연살해세포의 배양방법
ES2753259T3 (es) 2015-04-22 2020-04-07 Curevac Ag Composición que contiene ARN para el tratamiento de enfermedades tumorales
JP7337373B2 (ja) * 2019-07-29 2023-09-04 サイアス株式会社 抗原特異的t細胞の製造方法
US11730313B2 (en) * 2021-02-24 2023-08-22 Kirsten Wilkins Slow cooker liner system with integrated dividers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030050392A1 (en) * 1998-09-22 2003-03-13 Brother Kogyo Kabushiki Kaisha Water-based ink for ink jetting and ink jet recording method
US20030194395A1 (en) * 2001-09-17 2003-10-16 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
US20030134415A1 (en) 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
WO2003024312A2 (en) 2001-09-17 2003-03-27 Valeocyte Therapies Llc Cell therapy system
JP4699755B2 (ja) 2002-08-23 2011-06-15 ガブリエル ムルソフ, 腫瘍細胞におけるアポトーシスのHsp70/Hsp70ペプチド依存性誘導物質としてのグランザイムBの使用
US7435592B2 (en) * 2003-05-13 2008-10-14 Immunovative Therapies, Ltd. Compositions for allogeneic cell therapy
US7402431B2 (en) 2004-03-01 2008-07-22 Immunovative Therapies, Ltd. T-cell therapy formulation
DK2573166T3 (da) * 2004-02-26 2016-07-04 Immunovative Therapies Ltd Fremgangsmåder til fremstilling af T-celler til celleterapi
NO2606125T3 (de) 2010-08-20 2018-04-21

Also Published As

Publication number Publication date
AU2011291477B2 (en) 2016-07-28
HUE036094T2 (hu) 2018-06-28
US20120045423A1 (en) 2012-02-23
JP6525946B2 (ja) 2019-06-05
JP2013536232A (ja) 2013-09-19
DK2606125T3 (en) 2018-03-05
JP2017061558A (ja) 2017-03-30
CA2808873C (en) 2020-02-18
SG10201510524TA (en) 2016-01-28
KR101900807B1 (ko) 2018-11-08
PL2606125T3 (pl) 2018-05-30
US10385315B2 (en) 2019-08-20
WO2012024666A3 (en) 2012-05-18
US20130196428A1 (en) 2013-08-01
EP2606125A2 (de) 2013-06-26
CN103068973A (zh) 2013-04-24
ES2660577T3 (es) 2018-03-23
KR20130103485A (ko) 2013-09-23
US20130195825A1 (en) 2013-08-01
WO2012024666A2 (en) 2012-02-23
SG187846A1 (en) 2013-03-28
EP2606125B1 (de) 2017-11-22
CA2808873A1 (en) 2012-02-23
IL224813B (en) 2020-06-30
TR201802334T4 (tr) 2018-03-21
EP2606125A4 (de) 2014-03-19
NO2606125T3 (de) 2018-04-21
PT2606125T (pt) 2018-02-27
BR112013003989A2 (pt) 2017-11-14
CN108245673A (zh) 2018-07-06
AU2011291477A1 (en) 2013-04-04
BR112013003989B1 (pt) 2020-11-24

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