JP6320717B2 - X-ray diagnostic equipment - Google Patents

Description

  Embodiments described herein relate generally to an X-ray diagnostic apparatus.

  There is a mammography examination for finding breast cancer using a breast X-ray diagnostic apparatus (hereinafter referred to as a mammography apparatus). When a lesion such as calcification that is suspected to be malignant is detected by a mammography examination, the examiner determines the position of the lesion using the stereo imaging function of the mammography apparatus. The examiner inserts a collection needle of a dedicated device (mammotome) at the determined position of the lesion, and sucks and collects the tissue. The examiner diagnoses the collected diseased tissue. This technique is called mammography-guided biopsy test (hereinafter referred to as biopsy test).

  In the biopsy examination, the examiner X-rays the collected tissue specimen using an X-ray imaging apparatus for specimen imaging, and confirms whether the target calcified tissue can be collected. When it is confirmed that the target cannot be collected, the examiner collects the tissue sample again. In order to confirm the lesion in the tissue specimen, image quality characteristics (low energy X-ray, high resolution, high contrast, etc.) unique to the mammography apparatus are desirable instead of a general X-ray diagnostic apparatus.

  Breast X-ray imaging (stereo imaging) and specimen X-ray imaging in the biopsy examination are performed using separate X-ray diagnostic apparatuses. Specifically, stereo imaging of the breast is performed using a mammography apparatus. X-ray imaging of a specimen is performed using an X-ray diagnostic apparatus used for other examinations. Since the X-ray diagnostic apparatus used for other examinations is located in a different place in the examination facility from the mammography apparatus, it must be moved to another place and photographed in order to photograph the tissue specimen. , The burden on the examiner's subject. Furthermore, since the X-ray diagnostic apparatus is not an apparatus dedicated to tissue specimen imaging, it is difficult to ensure image quality such as high resolution and high contrast required for an X-ray image of a tissue specimen.

  X-ray imaging of a specimen in a biopsy examination may be performed using a mammography apparatus. The examiner determines the position of the lesion by stereo imaging of the breast and positions the collection needle. Subsequently, the examiner inserts a mammotome collection needle into the determined position of the breast and takes a tissue sample. At this time, the breast is fixed to the mounting surface of the mammography apparatus by a compression plate. However, here, in order to perform X-ray imaging of a specimen using the same mammography apparatus, it is necessary to replace the breast fixed on the placement surface with the specimen. Specifically, it is necessary to remove the collection needle inserted into the breast, release the fixation of the breast fixed to the placement surface, remove the breast from the placement surface, and place the specimen on the placement surface. If the biopsy test confirms that the target has not been collected, the examiner must collect the tissue sample again. Therefore, if it is confirmed that the target has not been collected, the subject must return to the hospital and undergo a biopsy test again, which is a burden on the subject.

JP 2008-272093 A

  An object is to provide an X-ray diagnostic apparatus that can improve examination efficiency.

An X-ray diagnostic apparatus according to this embodiment includes an X-ray tube that generates X-rays, an X-ray detector that detects X-rays generated from the X-ray tube, and the X-ray tube and the X-ray detector. A placement surface having a placement portion for a subject and a placement portion for a sample collected from the subject on the same plane , the X-ray detector, and the front A mounting table support mechanism that supports the mounting surface, an X-ray tube support mechanism that supports the X-ray tube so as to be rotatable about a predetermined rotation axis, and a solid angle of X-rays generated from the X-ray tube. and irradiation Ino limiter for limiting, before Symbol the radiation field in the mounting surface of the X-rays generated from the X-ray tube, the mounting portion and the specimen for the subject in the mounting surface And a switching unit that selectively switches between the mounting part for mounting.

The figure which shows the structure of the X-ray diagnostic apparatus which concerns on this embodiment. The figure which shows an example of the external appearance of the X-ray diagnostic apparatus which concerns on this embodiment. The figure which shows an example of the mounting surface of FIG. The figure which shows the other example of the mounting surface of FIG. The figure which shows an example of the switching correspondence table regarding irradiation field switching. The figure for demonstrating irradiation field switching to the irradiation field F1. The figure for demonstrating irradiation field switching to the irradiation field F2. The figure for demonstrating irradiation field switching to the irradiation field F3. The figure for demonstrating irradiation field switching to the irradiation field F4. The figure which shows an example of the corresponding | compatible table which shows a response | compatibility with the X-ray condition about each irradiation field regarding an irradiation field switching, and image processing. The figure which shows typically the typical flow of the biopsy test | inspection which concerns on this embodiment. The figure which shows an example of the breast stereo image which concerns on this embodiment. The figure which shows an example of the sample X-ray image which concerns on this embodiment. FIG. 10 is a diagram showing a display example of a breast X-ray image and a specimen X-ray image by a display unit according to application example 1. The figure which shows the example of a display of the breast stereo image and sample X-ray image by the display part which concerns on the application example 2. FIG. The figure which shows the example of a display of the breast cross-sectional image and sample X-ray image by the display part which concerns on the application example 3. FIG. The figure which shows an example of the biopsy test report which concerns on the application example 4. FIG. The figure which shows an example of the X-ray protective mechanism of the mounting base installation type which concerns on the application example 5. FIG. The figure which shows an example of the sample collection mechanism installation type X-ray protection mechanism which concerns on the application example 5. FIG.

  Hereinafter, an X-ray diagnostic apparatus 1 according to an embodiment will be described with reference to the drawings. In the following description, components having substantially the same function and configuration are denoted by the same reference numerals, and redundant description will be given only when necessary.

  It is assumed that the subject according to the present embodiment is a breast.

  FIG. 1 is a diagram showing a configuration of the X-ray diagnostic apparatus 1. The X-ray diagnostic apparatus 1 has an imaging mechanism 2. FIG. 2 is a diagram illustrating an example of the appearance of the X-ray diagnostic apparatus 1. As shown in FIG. 2, the imaging mechanism 2 includes a mounting table support mechanism 3 and an X-ray tube support mechanism 4. The mounting table support mechanism 3 and the X-ray tube support mechanism 4 are connected to a shaft portion 6 that is horizontally attached to the column 5. The mounting table support mechanism 3 and the X-ray tube support mechanism 4 are supported by the support column 5 so as to be individually rotatable about the axis of the shaft portion 6 as the rotation center axis R. The rotation direction around the rotation center axis R is defined as β direction.

  An X-ray tube 7 is provided at the end of the X-ray tube support mechanism 4. The X-ray tube 7 generates X-rays in response to application of a high voltage and supply of a filament current from the high voltage generator 8.

  A mounting table 9 is provided at the end of the mounting table support mechanism 3 so as to face the X-ray tube 7. An X-ray detector 10 is provided inside the mounting table 9. The X-ray detector 10 is realized by, for example, a flat panel detector (hereinafter referred to as FPD). The FPD has a plurality of elements arranged two-dimensionally. Each element detects X-rays generated from the X-ray tube 7 and converts the detected X-rays into electric signals. An electric signal generated in each element is output to an analog-to-digital converter (hereinafter referred to as an A / D converter) (not shown). The A / D converter converts an electrical signal into digital data. The A / D converter outputs digital data to the image generator 21.

  The rotation angle of the X-ray tube support mechanism 4 is defined as a rotation angle around the rotation center axis R with the uppermost portion of the circular orbit O being 0 °. The rotation angle of the mounting table support mechanism 3 is defined as a rotation angle around the rotation center axis R with the top of the same circular orbit O as the X-ray tube support mechanism 4 being 0 °. When the rotation angle of the mounting table support mechanism 3 is 0 °, the detection surface of the X-ray detector 10 is horizontal with respect to the installation surface of the X-ray diagnostic apparatus 1.

  The mounting table 9 has a mounting surface 11 on a surface facing the X-ray tube 7. The compression plate 12 is attached to the mounting table support mechanism 3 between the mounting surface 11 and the X-ray tube 7 so as to be movable in a direction approaching or separating from the mounting surface 11. The direction in which the mounting surface 11 and the compression plate 12 approach or separate from each other is taken as the arrow α direction. The mounting surface 11 is provided together with the compression plate 12 supported by the mounting table support mechanism 3 so as to be movable in the direction of the arrow α in order to compress the breast in a slab shape.

  The mounting table support mechanism 3 is equipped with a sample collection mechanism 13 above the mounting table 9. The sample collection mechanism 13 incorporates a collection drive unit 15 for driving the sample collection mechanism 13 and collecting a tissue sample under the control of the collection control unit 14. The sample collection mechanism 13 has a collection needle 16 for collecting a tissue sample. The collection needle 16 can be moved in the direction of the arrow α by the power of the collection drive unit 15. The sample collection mechanism 13 and the collection needle 16 are positioned so that the collection needle 16 can pass through a through hole formed in the center of the compression plate 12. Note that the sample collection mechanism 13 may be provided in a part other than the mounting table support mechanism 3. The sample collection mechanism 13 may have a configuration that is detachable from the imaging mechanism 2.

  The X-ray diagnostic apparatus 1 according to the present embodiment, together with the imaging mechanism 2, includes an image generation unit 21, an image processing unit 22, a reconstruction unit 23, an association unit 24, an input unit 25, a storage unit 26, a display unit 27, and an interface unit. 28, an imaging control unit 29, an X-ray control unit 30, a drive control unit 31, and a system control unit 32.

  The image generator 21 performs preprocessing on the digital data output from the X-ray detector 10 to generate an X-ray image. Image preprocessing includes correction of non-uniform sensitivity between channels in the X-ray detector 10 and correction for dropout. The image generation unit 21 outputs the generated X-ray image to the storage unit 26 described later.

  The image processing unit 22 performs contrast processing, frequency processing, dynamic range processing, noise reduction processing, and the like on an X-ray image acquired from the storage unit 26 described later.

  The reconstruction unit 23 reconstructs a cross-sectional image based on a plurality of X-ray images related to a plurality of positions of the X-ray tube 7.

  The associating unit 24 is generated by stereo imaging (hereinafter referred to as a breast stereo image) with a breast as an imaging target, an X-ray image (hereinafter referred to as a specimen X-ray image) with a specimen as an imaging target, and mammography examination. An X-ray image (hereinafter referred to as a breast X-ray image) obtained by imaging the entire breast is associated as a DICOM image of the same subject. Note that an X-ray image in which both the breast and the specimen are imaged may be associated as a DICOM image of the same subject.

  The input unit 25 inputs an X-ray condition desired by the examiner, an X-ray imaging position, an X-ray imaging start and end, and the like. The input unit 25 inputs various instructions, commands, information, selections, settings, and the like from the examiner or the like to the system control unit 32 described later.

  The storage unit 26 stores an inspector's instruction supplied from the input unit 25. The storage unit 26 stores various data. Note that the switching correspondence table may be changed by the inspector via the input unit 25. The storage unit 26 may also store an X-ray image generated by the image generation unit 21, an X-ray image processed by the image processing unit 22, an X-ray image reconstructed by the reconstruction unit 23, and the like. good. The storage unit 26 appropriately outputs the stored X-ray image to the image processing unit 22, the reconstruction unit 23, the display unit 27, the interface unit 28, and the like.

  The display unit 27 displays various information on the monitor. For example, the display unit 27 displays an X-ray image generated by the image generation unit 21 or an X-ray image processed by the image processing unit 22. The display unit 27 may read and display arbitrary image data stored in the storage unit 26.

  The interface unit 28 is connected to a PACS (Picture Archiving and Communication Systems) (not shown) and other computers via a network.

  The imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 to cause the imaging mechanism 2 to perform X-ray imaging. The imaging control unit 29 controls the X-ray tube support mechanism 4 and the irradiation field limiter 33 to change the irradiation field on the placement surface 11 of the X-rays generated from the X-ray tube 7 on the placement surface 11. It selectively switches between the breast placing part P1 and the specimen placing part P2. In the case of mammography examination, the imaging control unit 29 switches the irradiation field to the entire detection surface of the X-ray detector 10.

  The collection control unit 14 controls the collection drive unit 15 to cause the sample collection mechanism 13 to collect a tissue sample. The collection control unit 14 controls the collection driving unit 15 to collect a sample from the breast placed on the placement surface 11.

  The system control unit 32 functions as the center of the X-ray diagnostic apparatus 1. The system control unit 32 comprehensively controls each component included in the X-ray diagnostic apparatus 1 to realize various operations according to the present embodiment.

  Hereinafter, an operation example of the X-ray diagnostic apparatus 1 according to the present embodiment will be described.

  First, the mounting surface 11 will be described. FIG. 3 is a diagram illustrating an example of the placement surface 11 of FIG. The mounting surface 11 is a part of the surface of the mounting table 9 that faces the X-ray tube 7. The placement surface 11 includes a breast placement portion P1 and a sample placement portion P2 collected from the breast. The specimen mounting portion P2 is provided on the side of the mounting surface 11 where the mounting table support mechanism 3 is installed. The breast placement portion P1 is provided on the other side of the placement surface 11. The breast placing part P1 and the specimen placing part P2 are provided apart from each other. The breast placement portion P1 and the specimen placement portion P2 are provided at the end portion of the placement surface 11 in FIG. 3, but may be provided inside the placement surface 11 from the end portion. In practice, the specimen placement portion P2 is provided in a portion of the placement surface 11 that does not interfere with mammography inspection and biopsy inspection. Moreover, since the mounting surface 11 is tilted in a state where the breast and the specimen are mounted, the mounting surface 11 is preferably formed of a non-slip material having a high friction coefficient such as resin. The sample mounting part P2 has a first sample mounting part P21 and a second sample mounting part P22. In addition, the sample mounting part P2 may be one or three or more. FIG. 4 is a view showing another example of the placement surface 11 of FIG. The case where the magnitude | sizes of the breast mounting part P1 and the sample mounting part P2 differ is shown. As shown in FIG. 4, the sizes of the breast placing portion P1 and the sample placing portion P2 may be different.

  Next, irradiation field switching performed under the control of the system control unit 32 between the breast placing part P1 and the specimen placing part P2 will be described. FIG. 5 is a diagram illustrating an example of a switching correspondence table regarding irradiation field switching. The switching correspondence table associates the rotation angle of the X-ray tube support mechanism 4 with the size and shape of the opening of the irradiation field limiter 33 for each of the sights of the plurality of irradiation fields. The aim of the irradiation field is determined by the rotation angle of the X-ray tube support mechanism 4 and the size and shape of the opening of the irradiation field limiter 33. Specifically, the irradiation field relating to the present embodiment is classified into an irradiation field for biopsy inspection and an irradiation field for mammography inspection. The irradiation fields for biopsy inspection are irradiation fields F1, F2, and F3, and the irradiation field for mammography inspection is irradiation field F4. The irradiation field F1 is defined as an irradiation field that is aimed at the breast placement portion P1. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F1 is θ1 + γ or θ1-γ, and the size and shape of the opening of the irradiation field limiter 33 are A1. The irradiation field F2 is defined as an irradiation field that is aimed at the first specimen placement portion P2. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F2 is θ2, and the size and shape of the opening of the irradiation field limiter 33 are A2. The irradiation field F3 is defined as an irradiation field that is aimed at the second specimen mounting portion P2. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F3 is θ3, and the size and shape of the opening of the irradiation field limiter 33 are A3. The irradiation field F4 is an irradiation field related to mammography examination. The irradiation field F4 is defined as an irradiation field that is aimed at the entire detection surface of the X-ray detector 10. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F4 is θ4, and the size and shape of the opening of the irradiation field limiter 33 are A4. The switching correspondence table is stored in the storage unit 26 in advance.

  When the examiner inputs an instruction to switch to the irradiation field F1 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the breast placement portion P1. By setting the rotation angle of the X-ray tube support mechanism 4 to θ1 ± γ and the size and shape of the opening of the irradiation field limiter 33 to A1, the irradiation field is switched to the breast mounting portion P1. When the examiner inputs an instruction to switch to the irradiation field F2 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the first specimen placement portion P21. By setting the rotation angle of the X-ray tube support mechanism 4 to θ2 and the size and shape of the opening of the irradiation field limiter 33 to A2, the X-ray tube support mechanism 4 can be switched to the first specimen mounting portion P21. When the inspector inputs a switching instruction to the irradiation field F3 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the second specimen placement portion P22. By setting the rotation angle of the X-ray tube support mechanism 4 to θ3 and the size and shape of the opening of the irradiation field limiter 33 to A3, the irradiation field is switched to the second specimen mounting portion P22. When the inspector inputs a switching instruction to the irradiation field F4 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and sets the irradiation field over the entire detection surface of the X-ray detector 10. Switch. By setting the rotation angle of the X-ray tube support mechanism 4 to θ4 and the size and shape of the opening of the irradiation field limiter 33 to A4, the irradiation field is switched over the entire detection surface of the X-ray detector 10. Note that a sensing unit that senses the pressure applied to the specimen mounting portion P2 may be provided, and the irradiation field switching may be started when the sensing unit senses a pressure that is equal to or higher than a predetermined value.

  FIG. 6 is a diagram for explaining irradiation field switching to the irradiation field F1. The irradiation field F1 is used in the case of breast stereo imaging. In FIG. 6, the irradiation field indicates that it is aimed at the breast placement portion P <b> 1 on the placement surface 11. When a switching instruction to the irradiation field F <b> 1 is input via the input unit 25, the system control unit 32 reads items related to the irradiation field F <b> 1 in the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table and performs irradiation field switching. The imaging control unit 29 issues an instruction signal for irradiation field switching to the drive control unit 31. The drive control unit 31 changes the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33 to switch the irradiation field to the breast placement portion P1. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ1 + γ or θ1−γ under the control of the drive control unit 31. For the sake of specific explanation, θ1 is 0 °, γ is 15 °, and the rotation angle θ1 ± γ is ± 15 °. Here, the rotation angle θ1 ± γ is a positive rotation angle and a negative rotation angle in breast stereo imaging. The aperture drive unit 41 moves the aperture blades of the irradiation field limiter 33 under the control of the drive control unit 31, and changes the size and shape of the aperture to A1. The size of the opening and the opening of the aperture blade for realizing the shape A1 are stored in the storage unit 26 in advance. In addition, in order to simplify the above description, the rotation angle of the mounting table support mechanism 3 is set to 0 °. The mounting table support mechanism driving unit 35 changes the rotation angle of the mounting table support mechanism 3 under the control of the drive control unit 31. When the rotation angle of the mounting table support mechanism 3 is ω, the rotation angle of the X-ray tube support mechanism 4 is read as + ω in the following description. The irradiation field F1 may be used for normal mammography, not mammography.

  FIG. 7 is a diagram for explaining irradiation field switching to the irradiation field F2. In FIG. 7, the irradiation field indicates that it is aimed at the first specimen placement portion P <b> 21 on the placement surface 11. When a switching instruction to the irradiation field F <b> 2 is input via the input unit 25, the system control unit 32 reads items related to the irradiation field F <b> 2 in the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table and performs irradiation field switching. The imaging control unit 29 issues an instruction signal for irradiation field switching to the drive control unit 31. The drive control unit 31 switches the irradiation field to the first specimen placement portion P21 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ2 under the control of the drive control unit 31. In order to make the description concrete, for example, the rotation angle θ2 is set to 15 °. The aperture drive unit 41 moves the diaphragm blades of the irradiation field limiter 33 under the control of the drive control unit 31, and changes the size and shape of the aperture to A2. The aperture size and the opening of the aperture blade for realizing the shape A2 are stored in the storage unit 26 in advance.

  FIG. 8 is a diagram for explaining irradiation field switching to the irradiation field F3. In FIG. 8, the irradiation field indicates that it is aimed at the second specimen placement portion P <b> 22 on the placement surface 11. When a switching instruction to the irradiation field F <b> 3 is input via the input unit 25, the system control unit 32 reads items related to the irradiation field F <b> 3 in the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table and performs irradiation field switching. The imaging control unit 29 issues an instruction signal for irradiation field switching to the drive control unit 31. The drive control unit 31 switches the irradiation field to the second specimen mounting portion P22 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ3 under the control of the drive control unit 31. In order to make the description concrete, for example, the rotation angle θ3 is set to −15 °. The aperture drive unit 41 moves the aperture blades of the irradiation field limiter 33 under the control of the drive control unit 31, and changes the size and shape of the aperture to A3. The opening size of the aperture and the opening degree of the aperture blade for realizing the shape A3 are stored in the storage unit 26 in advance.

  FIG. 9 is a diagram for explaining irradiation field switching to the irradiation field F4 at the time of mammography inspection. The irradiation field F4 is used for mammography examination. In FIG. 9, the irradiation field indicates that the entire detection surface of the X-ray detector 10 on the placement surface 11 is aimed. When a switching instruction to the irradiation field F4 is input via the input unit 25, the system control unit 32 reads items related to the irradiation field F4 in the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table and performs irradiation field switching. The imaging control unit 29 issues an instruction signal for irradiation field switching to the drive control unit 31. The drive control unit 31 switches the irradiation field to the entire detection surface of the X-ray detector 10 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ4 under the control of the drive control unit 31. In order to make the description more specific, the rotation angle θ4 is set to 0 °. The aperture drive unit 41 moves the aperture blades of the irradiation field limiter 33 under the control of the drive control unit 31 and changes the size and shape of the aperture to A4. The opening size of the aperture and the aperture of the diaphragm blade for realizing the shape A4 are stored in the storage unit 26 in advance.

  Next, X-ray condition switching and image processing switching performed under the control of the system control unit 32 along with irradiation field switching will be described. FIG. 10 is a diagram showing an example of a correspondence table showing correspondence between X-ray conditions and image processing for each irradiation field related to irradiation field switching. The correspondence table defines X-ray conditions and image processing for each irradiation field. In the case of the irradiation field F1, the X-ray condition is X1, and the image processing is P1. In the case of the irradiation field F2, the X-ray condition is X2, and the image processing is P2. In the case of the irradiation field F3, the X-ray condition is X3, and the image processing is P3. In the case of the irradiation field F4, the X-ray condition is X4 and the image processing is P4. The correspondence table is stored in the storage unit 26 in advance. When switching to the irradiation field F1, the X-ray condition is switched to X1, and the image processing is switched to P1. When switching to the irradiation field F2, the X-ray condition is switched to X2, and the image processing is switched to P2. When switching to the irradiation field F3, the X-ray condition is switched to X3, and the image processing is switched to P3. When switching to the irradiation field F4, the X-ray condition is switched to X4, and the image processing is switched to P4.

  When the inspector inputs an instruction to switch the irradiation field via the input unit 25, the X-ray condition switching is performed in conjunction with the irradiation field switching. Specifically, the system control unit 32 reads the correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table and issues an X-ray condition switching instruction signal to the X-ray control unit 30. The X-ray control unit 30 switches the X-ray condition to X1, X2, X3, and X4 according to the irradiation fields F1, F2, and F3. X-ray conditions X1, X2, X3, and X4 are stored in the storage unit 26 in advance. Note that the X-ray conditions X1, X2, X3, and X4 may be changed by the examiner via the input unit 25. Differences in the X-ray conditions X1, X2, X3, and X4 are, for example, X-ray tube voltage, tube current time product, anode material, and quality compensation filter. As the X-ray conditions X1, X2, X3, and X4, an X-ray condition appropriate for each irradiation field or an X-ray condition according to the examiner's preference is set.

  When the inspector inputs an irradiation field switching instruction via the input unit 25, image processing switching is performed in conjunction with the irradiation field switching. Specifically, the system control unit 32 reads the correspondence table stored in the storage unit 26. The system control unit 32 outputs an image processing switching instruction signal to the image processing unit 22 based on the read correspondence table. The image processing unit 22 switches the image processing to P1, P2, P3, and P4 according to the irradiation fields X1, X2, X3, and X4. The image processes P1, P2, P3, and P4 are stored in the storage unit 26 in advance. Note that the image processing P1, P2, P3, and P4 may be changed by the inspector via the input unit 25. Differences between the image processes P1, P2, P3, and P4 are, for example, resolution and contrast. For the image processing P1, P2, P3, and P4, an image processing method appropriate for each irradiation field or an image processing method according to the examiner's preference is set.

  When the irradiation field switching is completed, the system controller 32 executes X-ray imaging when the inspector inputs an instruction via the input unit 25. In the X-ray imaging, the image generator 21 generates an X-ray image based on detection signals from a plurality of elements included in the irradiation field range in the X-ray detector 10. Specifically, the X-ray detector 10 reads the detection signal, limited to the elements included in the irradiation range among the plurality of elements included in the X-ray detector 10. The image generation unit 21 generates an X-ray image based on the detection signal read out in a limited manner. The X-ray detector 10 switches the detection signal readout range in accordance with irradiation field switching. A correspondence table between the irradiation field and the read range of the detection signal is stored in the storage unit 26. That is, when the irradiation field aim is the breast placement portion P1, the image generation unit 21 generates an X-ray image in which the breast placed on the breast placement portion P1 is depicted. When the irradiation field aim is the first specimen placement portion P21, the image generation unit 21 generates an X-ray image in which the specimen placed on the first specimen placement portion P21 is depicted. When the irradiation field aim is the second specimen placement portion P22, the image generator 21 generates an X-ray image in which the specimen placed on the second specimen placement portion P22 is depicted. The irradiation field aim is defined in the irradiation field switching correspondence table of FIG. 5 and is stored in the storage unit 26. Note that the matrix size of the X-ray image corresponds to the size of the irradiation field aim. When the size of the breast placement portion P1 and the size of the specimen placement portion P2 are the same as shown in FIG. 3, an X-ray image in which the breast placed on the breast placement portion P1 is depicted, the first specimen placement portion The matrix sizes of the X-ray image in which the specimen placed on P21 is depicted and the X-ray image in which the specimen placed on the second specimen placement portion P22 is depicted are equal. In the case of mammography examination, the irradiation field aim is the entire detection surface of the X-ray detector 10, so that the breast X-ray image generated in the mammography examination is larger than various X-ray images generated in the biopsy examination.

  Hereinafter, a series of operation examples in the present embodiment will be described with reference to FIG. FIG. 11 is a diagram schematically showing a typical flow of the biopsy test according to the present embodiment.

  First, stereo shooting for positioning is performed. Prior to stereo imaging, the imaging control unit 29 receives an instruction to switch from the entire detection surface of the X-ray detector 10 to the breast placement portion P1 input by the examiner via the drive control unit 31 input unit 25. The drive control unit 31 is controlled to switch the irradiation field from the entire detection surface of the X-ray detector 10 to the breast mounting portion P1. As the irradiation field is switched, the imaging control unit 29 controls the X-ray control unit 30 to change the X-ray condition for the entire detection surface of the X-ray detector 10 to the X-ray condition for the breast placement portion P1. Switch. Further, the system control unit 32 controls the image processing unit 22 in accordance with the irradiation field switching, and switches from the image processing for the breast X-ray image in the mammography examination to the image processing for the breast stereo image in the biopsy examination. In the biopsy test, it is not necessary to set the irradiation field for the mammography test before starting stereo imaging. The irradiation field may be set in the specimen placement portion P2, or may be set in the breast placement portion P1.

  When the subject's breast is placed on the placement surface 11 and preparation for stereo imaging is completed, the examiner inputs an imaging start instruction via the input unit 25. In response to the input of the instruction, the system control unit 32 causes the imaging mechanism 2 to perform stereo imaging of the breast (step S1). In step S <b> 1, the system control unit 32 transmits a shooting start instruction to the shooting control unit 29. The imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 according to the imaging start instruction, and the breast placed on the breast placement part P1 at two rotation angles of the X-ray tube support mechanism 4. X-ray. The image generation unit 21 or the reconstruction unit 23 generates a positive breast stereo image based on the detection signal from the X-ray detector 10 at the positive rotation angle, and the X-ray detector at the negative rotation angle. Based on the detection signal from 10, a negative breast stereo image is generated. FIG. 12 is a diagram illustrating an example of a breast stereo image. The display unit 27 displays the breast stereo image I1. The breast stereo image I1 includes a positive breast stereo image I11 and a negative breast stereo image I12. Note that normal X-ray imaging may be performed at a rotation angle of 0 ° instead of stereo imaging. However, since the target calcified region has a low contrast, in this embodiment, in order to increase the target rendering accuracy, in step S1, stereo imaging is performed instead of normal X-ray imaging.

  When stereo shooting is performed, the collection needle 16 is positioned. First, the system control unit 32 causes the sample collection mechanism 13 to perform the positioning process of the collection needle 16 (step S2). In step S2, the image processing unit 22 performs image processing for enhancing the range where the target TA is captured in the breast stereo image I1. Image processing includes, for example, contrast enhancement processing and resolution improvement processing. The breast stereo image I1 is displayed on the display unit 27. The examiner observes the displayed breast stereo image I1, identifies the position of the target TA inside the breast, and determines the insertion position of the collection needle 16. In the series of operations of the biopsy test, the breast is placed on the placement surface 11 and fixed by the compression plate 12. The examiner inputs an instruction for moving the determined collection needle 16 to the insertion position via the input unit 25. The collection control unit 14 drives the collection drive unit 15 to move the collection needle 16 in accordance with a movement instruction via the input unit 25, and moves the collection needle 16 to the insertion position. The collection needle 16 is a hollow needle having an outer diameter of about 3 to 4 mm. Note that the insertion position of the collection needle 16 may be determined by performing image recognition processing for specifying the position of the target TA on the breast X-ray image I1.

  When step S2 is performed, the system control unit 32 causes the sample collection mechanism 13 to insert the collection needle 16 into the breast (step S3). In step S <b> 3, the system control unit 32 transmits an insertion instruction input by the examiner via the input unit 25 to the collection control unit 14. The collection control unit 14 drives the collection drive unit 15 according to the insertion instruction from the system control unit 32, and causes the sample collection mechanism 13 to insert the collection needle 16 into the breast.

  When step S3 is performed, the system control unit 32 causes the sample collection mechanism 13 to collect a sample from the breast (step S4). In step S <b> 4, the system control unit 32 transmits the collection instruction input by the examiner via the input unit 25 to the collection control unit 14. The collection control unit 14 drives the collection drive unit 15 in accordance with the collection instruction from the system control unit 32, sucks tissue cells with the collection needle 16 inserted into the breast, and collects the sample. The collected specimen is placed on the specimen placement portion P2 by the inspector. The X-ray diagnostic apparatus 1 further includes a sample placement unit that places the collected sample on the sample placement part P2, and the collected sample is placed on the sample placement part P2 under the control of the collection control unit 14. It may be placed.

  When step S4 is performed, the system control unit 32 causes the imaging control unit 29 to perform irradiation field switching (step S5). In step S5, the imaging control unit 29 controls the drive control unit 31 in response to a switching instruction from the breast placement part P1 to the specimen placement part P2 input by the examiner via the drive control unit 31 input unit 25. Then, the irradiation field is switched from the breast placing portion P1 to the specimen placing portion P2. Along with the irradiation field switching, the imaging control unit 29 controls the X-ray control unit 30 to switch from the X-ray condition for the breast mounting portion P1 to the X-ray condition for the sample mounting portion P2. Further, the system control unit 32 controls the image processing unit 22 in accordance with the irradiation field switching, and switches from the image processing for the breast stereo image to the image processing for the specimen X-ray image.

  When step S5 is performed, the system control unit 32 causes the imaging mechanism 2 to perform sample X-ray imaging (step S6). In step S6, the image generation unit 21 generates a specimen X-ray image I2. The display unit 27 displays the specimen X-ray image I2. FIG. 13 is a diagram illustrating an example of the specimen X-ray image I2. The display unit 27 may display the breast stereo image I1 and the specimen X-ray image I2 side by side. The breast stereo image I1 and the specimen X-ray image I2 are placed on the same placement surface 11 and photographed. Therefore, the system control unit 32 can capture the breast stereo image I1 and the specimen X-ray image I2 with the same geometric magnification.

  When step S6 is performed, the system control unit 32 determines whether there is an instruction to end shooting from the input unit 25 (step S7). When the inspector confirms that the target TA is shown in the specimen X-ray image I2, the inspector inputs an instruction to end imaging to the input unit 25. The presence of the target TA in the specimen X-ray image I2 means that a breast tissue specimen has been collected. If it is determined in step S7 that there is an instruction to end shooting, the series of operations in the present embodiment ends. If it is determined in step S7 that there is no instruction to end shooting, the process returns to step S2. In biopsy examinations, tissue sample collection often fails, so steps S2 to S7 are repeated. Therefore, the tissue specimen can be repeatedly collected without removing the breast fixed to the mounting surface 11, thereby reducing the burden on the examiner and the subject. In addition, the ability to perform tissue specimen collection and specimen X-ray imaging with the same apparatus reduces the burden on the examiner and the subject.

  As described above, according to the X-ray diagnostic apparatus 1 according to the present embodiment, breast stereo imaging, tissue sample collection, and specimen X-ray imaging in a biopsy test can be performed with the same apparatus. That is, breast stereography, tissue sample collection, and specimen X-ray photography can be performed without removing the breast fixed to the placement surface 11. Therefore, the burden on the examiner and the subject can be reduced because the tissue sample collection and the sample X-ray imaging can be repeated without removing the breast fixed to the placement surface 11. Further, the mammography test can be performed with the same apparatus as the biopsy test. That is, the image generated by the mammography test and the image generated by the biopsy test can be associated as a DICOM image of the same subject. Therefore, it becomes easy to use the inspection images of the mammography inspection and the biopsy inspection, and the combination display of a plurality of inspection images and the use for report creation are facilitated. Thus, the X-ray diagnostic apparatus 1 according to the present embodiment can improve the inspection efficiency of the biopsy test.

  Next, various application examples of this embodiment will be described. In the following description, components having substantially the same functions as those of the present embodiment are denoted by the same reference numerals, and redundant description will be given only when necessary.

(Application 1)
As described above, in the biopsy examination using the X-ray diagnostic apparatus 1, the image generation unit 21 generates the specimen X-ray image I2. In the mammography examination, the image generation unit 21 generates a breast X-ray image I3. The display unit 27 according to the application example 1 improves the examination efficiency of the biopsy examination by displaying the specimen X-ray image I2 on the breast X-ray image I3.

  FIG. 14 is a diagram illustrating a display example of the breast X-ray image I3 and the specimen X-ray image I2 by the display unit 27 according to the application example 1. The display unit 27 displays the breast X-ray image I3. The display unit 27 displays the sample X-ray image I2 in an overlapping manner with the predetermined display position of the breast X-ray image I3 as the center point based on the examiner's instruction input by the input unit 25. The predetermined display position is changed by an inspector's instruction via the input unit 25. The predetermined display position is set so that the specimen X-ray image I2 does not overlap the breast region in the breast X-ray image I3.

  The display of the specimen X-ray image I2 on the breast X-ray image I3 displayed on the display unit 27 will be specifically described. For example, the examiner clicks an icon for switching between display / non-display of the specimen X-ray image I2 displayed on the display unit 27 by a mouse operation, and thereby a predetermined X-ray image of the breast X-ray image I1 displayed on the display unit 27 is displayed. The specimen X-ray image I2 is displayed over the range. The display unit 27 may also display a mark M1 for indicating the correspondence between the target region TR inside the breast and the sample X-ray image I2 in the breast X-ray image I3. Specifically, the mark M1 is a circle surrounding the target region TR shown in FIG. 14, a straight line connecting the target region TR and the specimen X-ray image I2, or the like. For example, when the operator performs a mouse drag operation to specify the target region TR, the display unit 27 displays a circle that surrounds the target region TR and a straight line connecting the target region TR and the sample X-ray image I2 in the image. Furthermore, it is displayed in a superimposed manner. Note that the storage unit 26 may store the breast X-ray image I3, the mark M1 depicting the correspondence between the target region TR and the specimen X-ray image I2, and the display screen of the breast X-ray image I1 as a DICOM image.

  The specimen X-ray image I2 may overlap the breast area of the breast X-ray image I3, and the part of the breast area that overlaps with the specimen X-ray image I2 may become invisible. At that time, the examiner can move the display position of the specimen X-ray image I2 displayed on the display unit 27 by dragging the mouse. By moving the display position of the sample X-ray image I2, it is possible to make the breast region invisible by the sample X-ray image I2 visible.

  As described above, according to the X-ray diagnostic apparatus 1 according to the application example 1, the display unit 27 superimposes the sample X-ray image I2 generated by the biopsy test on the breast X-ray image I3 generated by the mammography test. Can be displayed. In other words, the breast area and the specimen area can be interpreted as a single image. Further, the mark M1 can be further superimposed on the image. The correspondence between the target region TR in the breast region and the specimen X-ray image I2 can be indicated by the mark. Accordingly, the examiner can easily interpret the breast X-ray image I3 and the specimen X-ray image I2. Thus, the X-ray diagnostic apparatus 1 according to the application example 1 can improve the examination efficiency of the biopsy examination.

(Application example 2)
The display unit 27 according to the application example 2 displays the breast stereo image and the specimen X-ray image in a layout for determining whether or not the target is collected in the biopsy test.

  FIG. 15 is a diagram illustrating a display example of a breast stereo image and a specimen X-ray image by the display unit 27 according to the application example 2. The breast stereo image has a breast stereo image before sampling and a breast stereo image after sampling. As shown in FIG. 15, in the application example 2, the display unit 27 determines whether or not the target TA has been collected in the biopsy test, so that a breast stereo image before specimen collection, a breast stereo image after specimen collection, and a specimen are collected. Display X-ray images side by side. As shown in FIG. 15, the display unit 27 assists the examiner in determining whether or not the target TA has been collected, so that a breast stereo image before sampling, a breast stereo image after sampling, and a sample X-ray are collected. Display images side by side in chronological order. The breast stereo image before sampling has a breast stereo image at a positive rotation angle before sampling and a breast stereo image at a negative rotation angle before sampling. The breast stereo image after sampling has a breast stereo image at a positive rotation angle after sampling and a breast stereo image at a negative rotation angle after sampling. In order to accurately perform the correspondence relationship between the targets TA drawn in each image, each image is preferably displayed in the same size. At this time, the display unit 27 may display the breast stereo image before sampling, the breast stereo image after sampling, and the sample X-ray image on a single screen by appropriately reducing the size. This improves the listability of the breast stereo image before specimen collection, the breast stereo image after specimen collection, and the specimen X-ray image, and facilitates observation of these images. The storage unit 26 may store a display screen of a breast stereo image before specimen collection, a breast stereo image after specimen collection, and a specimen X-ray image as DICOM images.

  Further, as shown in FIG. 15, the display unit 27 shows the correspondence between the targets TA depicted in each of the breast stereo image before sampling, the breast stereo image after sampling, and the sample region X-ray image. The mark M2 may be displayed. It means that both targets TA related by the mark M2 are the same. Specifically, the mark M2 is a straight line connecting the target TA in the specimen X-ray image and the target TA in the breast stereo image before sampling. The straight line mark is defined by a straight line connecting the start point and the end point designated by the operator via the input unit 25. When the start point and end point are designated by the operator, the display unit 27 displays a mark M2 connecting the designated start point and end point, a breast stereo image before sampling, a breast stereo image after sampling, and a sample X-ray. Display overlaid on the image. For example, in FIG. 15, it is assumed that the target TA is depicted in the breast stereo image before sampling, and the target TA is collected in the biopsy test. In this case, the target TA calculated in the sample X-ray image is drawn, and the target TA is not drawn in the breast stereo image after the sample is collected. That is, it has disappeared before and after sampling, that is, the sampling target TA has been sampled. Under such circumstances, the examiner instructs via the input unit 25 to associate the target TA drawn in the breast stereo image before sampling with the target TA drawn in the sample X-ray image. Upon receiving this instruction, the display unit 27 displays a mark M2 that associates both targets TA. By displaying the mark M2, the display unit 27 can make the observer clearly understand that the plurality of targets TA related by the mark M2 are the same. Note that the storage unit 26 may store a display screen of a breast stereo image before sampling, a breast stereo image after sampling, and a sample X-ray image on which the mark M2 is drawn as a DICOM image. Note that the breast stereo image after specimen collection, the specimen X-ray image, and the breast stereo image before specimen collection in which the mark M2 is drawn may be associated as a DICOM image of the same examination by the associating unit 24.

  As described above, the display unit 27 according to the application example 2 displays the breast stereo image before sampling, the breast stereo image after sampling, and the sample X-ray image side by side. Further, the same collection target TA among a plurality of images can be associated using the mark M2. Thereby, the display unit according to the application example 2 can easily determine whether the target TA has been collected. Thus, the X-ray diagnostic apparatus 1 according to the application example 2 can improve the examination efficiency of the biopsy examination.

(Application 3)
The display unit 27 according to the application example 3 displays an image generated by tomosynthesis imaging of a breast and a specimen X-ray image with a layout for determining whether or not the target TA has been collected in the biopsy test.

  FIG. 16 is a diagram illustrating a display example of a breast cross-sectional image and a specimen X-ray image by the display unit 27 according to the application example 3. As shown in FIG. 16, in application example 3, the display unit 27 determines whether or not the target TA has been collected in the biopsy test, so that the breast sectional image before specimen collection, the breast sectional image after specimen collection, and the specimen are collected. Display X-ray images side by side. When there is a mammary gland in the vicinity of the calcified region serving as the target TA, the target TA may not be drawn on the X-ray image in stereo imaging and normal X-ray imaging. In order to improve the rendering accuracy of the target TA, it is preferable to display a cross-sectional image generated by tomosynthesis imaging in which the breast is imaged stereoscopically. Hereinafter, a cross-sectional image generated by reconstructing a breast X-ray image generated by tomosynthesis imaging will be referred to as a breast cross-sectional image.

  When taking a breast tomosynthesis image before sampling, the irradiation field is aimed at the breast placement portion P1. The examiner gives an instruction to start tomosynthesis imaging via the input unit 25 before sampling. In response to an instruction to start tomosynthesis imaging, the imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 and mounts on the breast placement portion P1 at a plurality of rotation angles of the X-ray tube support mechanism 4. The placed breast is radiographed. For example, the plurality of rotation angles may be set to a plurality of rotation angles with 0 ° sandwiched between −φ and φ. Specifically, for example, tomosynthesis imaging starts the X-ray tube 7 from the position of the rotation angle of the X-ray tube support mechanism 4 at −15 °, and generates X-rays at regular intervals while continuously moving in the β direction. Repeat image collection. X-ray imaging ends at the position where the X-ray tube 7 is at a rotation angle of 15 ° of the X-ray tube support mechanism 4. The image generator 21 generates a plurality of X-ray images based on detection signals from the X-ray detector 10 at a plurality of rotation angles. The storage unit 26 stores a plurality of breast X-ray images generated by tomosynthesis imaging. The reconstruction unit 23 reconstructs a plurality of breast X-ray images and generates breast volume data. Based on the breast volume data, the image processing unit 22 generates a breast cross-sectional image before sampling that represents a plurality of parallel cross-sections. A cross-sectional image of the breast after specimen collection is also taken in the same manner.

  As shown in FIG. 16, the display unit 27 displays a plurality of breast cross-sectional images side by side in the vertical direction corresponding to the tomographic position. Thereby, the examiner can three-dimensionally grasp the target TA drawn on the breast cross-sectional image before sampling from the cross-sectional image. Therefore, in particular, when there is a mammary gland in the vicinity of the calcified region serving as the target TA, it is easier to grasp the target TA than when observing a breast stereo image and a breast X-ray image.

  As shown in FIG. 16, the display unit 27 supports a judgment by the examiner as to whether or not the target TA has been collected, so that a breast cross-sectional image before sampling, a breast cross-sectional image after sampling, and a sample X-ray are collected. Display images side by side in chronological order. The display unit 27 may display the breast cross-sectional image before sampling, the breast cross-sectional image after sampling, and the sample X-ray image on one screen by appropriately reducing the size. This improves the listing of the breast cross-sectional image before specimen collection, the breast cross-sectional image after specimen collection, and the specimen X-ray image, and facilitates observation of these images. Note that the storage unit 26 may store a display screen of a breast cross-sectional image before sampling, a breast cross-sectional image after sampling, and a sample X-ray image as DICOM images.

  In addition, as shown in FIG. 16, the display unit 27 is a mark indicating the correspondence between the target TAs depicted in each of the breast cross-sectional image before specimen collection, the breast cross-sectional image after specimen collection, and the specimen X-ray image. M3 may be displayed. It means that both targets TA related by the mark M3 are the same. Specifically, the mark M3 is a straight line connecting the target TA in the sample X-ray image and the target TA in the breast cross-sectional image before sampling. The straight line mark is defined by a straight line connecting the start point and the end point designated by the operator via the input unit 25. When the start point and the end point are designated by the operator, the display unit 27 displays a mark M3 connecting the designated start point and end point, a breast cross-sectional image before sampling, a breast cross-sectional image after sampling, and a sample X-ray. Display overlaid on the image. For example, in FIG. 16, it is assumed that the target TA is depicted in the breast cross-sectional image before sampling, and the target TA is collected in the biopsy test. In this case, the target TA collected in the specimen X-ray image is depicted, and the target TA is not depicted in the breast cross-sectional image after the specimen is collected. That is, it has disappeared before and after sampling, that is, the sampling target TA has been sampled. Under such circumstances, the examiner instructs via the input unit 25 to associate the target TA drawn on the breast cross-sectional image before sampling with the target TA drawn on the sample X-ray image. In response to this instruction, the display unit 27 displays a mark associating both targets TA. By displaying the mark M3, the display unit 27 can make the observer clearly understand that the plurality of targets TA related by the mark M3 are the same. Note that the storage unit 26 may store a display screen of a breast cross-sectional image before sampling, a breast cross-sectional image after sampling, and a sample X-ray image on which the mark M3 is depicted as a DICOM image.

  Further, the image processing unit 22 may determine whether or not the target TA has been acquired by performing image analysis on the breast cross-sectional image before sampling and the breast cross-sectional image after sampling. Specifically, the image analysis is realized by a pattern recognition process or the like. The determination result is displayed on the display unit 27. As shown in FIG. 16, the display unit 27 further displays the analysis results side by side on the display screen, thereby assisting the examiner to determine whether or not the target TA has been collected.

  As described above, the display unit 27 according to the application example 3 displays the breast cross-sectional image before sampling, the breast cross-sectional image after sampling, and the sample X-ray image side by side. Thereby, the examiner can three-dimensionally grasp the target TA drawn on the breast cross-sectional image before sampling from the cross-sectional image. Further, the same collection target TA among a plurality of images can be associated using the mark M3. Thereby, the display unit according to the application example 3 can easily determine whether the target TA has been collected. Therefore, the positioning accuracy of the collecting needle 16 is improved. Furthermore, by performing image analysis on the breast cross-sectional image before sampling and the breast cross-sectional image after sampling, it is possible to determine whether the target TA has been sampled and display the analysis result. Thus, the X-ray diagnostic apparatus 1 according to the application example 3 can improve the inspection efficiency of the biopsy test.

(Application 4)
In the above-described embodiment, in the biopsy examination using the X-ray diagnostic apparatus 1, since the X-ray imaging is performed a plurality of times, the examiner needs to evaluate the exposure dose of the subject. During the biopsy examination, a report on the exposure dose is created in order to evaluate the exposure dose. In addition, information such as the volume of the collected specimen is also important in biopsy test reports. In the application example 4, the display unit 27 displays the sample X-ray image, the information regarding the accumulated exposure dose during the examination, and the volume of the sample side by side.

  FIG. 17 is a diagram illustrating an example of a biopsy test report according to Application Example 4. The image processing unit 22 according to the application example 4 has a dose calculation function and a volume calculation function. In the dose calculation function, the image processing unit 22 is a function for calculating the cumulative exposure dose of the subject in the biopsy test. For example, the image processing unit 22 calculates an average mammary gland dose (hereinafter referred to as “AGD”) and an incident surface dose (hereinafter referred to as “ESD”). In the volume calculation function, the image processing unit 22 is a function for calculating the volume of the specimen. In FIG. 17, four volumes of Total, Max, Min, and Ave are displayed as sample volumes. Total indicates the total volume of the collected specimen. Max represents the volume of the sample with the largest volume among the collected samples. Min indicates the volume of the sample having the smallest volume among the collected samples. Ave indicates the average value of the volume of the collected specimen. Note that the storage unit 26 may store the display screen of the biopsy test report of FIG. 17 as a DICOM image.

  As described above, the display unit 27 according to the application example 4 displays the sample X-ray image, the information related to the accumulated exposure dose during the examination, and the volume of the sample side by side. Thereby, the display unit 27 according to the application example 4 can easily grasp the accumulated exposure dose, the sample image, and the sample information in the biopsy test. Thus, the X-ray diagnostic apparatus 1 according to the application example 4 can improve the examination efficiency of the biopsy examination.

(Application example 5)
In the above-described embodiment, in the biopsy examination using the X-ray diagnostic apparatus 1, X-ray imaging is performed a plurality of times, and thus it is necessary to reduce the exposure dose to the subject. In the application example 5, the X-ray diagnostic apparatus 1 further includes an X-ray protection mechanism 42 for reducing the exposure dose to the subject. The X-ray protection mechanism 42 reduces the exposure dose to the subject when the irradiation field is aimed at the specimen placement portion P2.

  FIG. 18 is a diagram illustrating an example of a mounting table installation type X-ray protection mechanism 42 according to Application Example 5. The mounting table X-ray protection mechanism 42 is installed on the mounting table 9. The X-ray protection mechanism 42 is formed of a heavy metal such as lead for shielding X-rays. The X-ray protection mechanism 42 is designed in shape and size so as to shield the X-rays generated by the X-ray tube 7 and irradiated on the subject. Further, the X-ray protection mechanism 42 shields X-rays that are reflected by the placement surface 11, the X-ray detector 10, and the like and irradiated to the subject. The X-ray protection mechanism 42 is installed so that X-rays do not interfere with the incidence on the sample placement part P2 and the breast placement part P1. The X-ray protection mechanism 42 is installed on the mounting table 9 or the sample collection mechanism 13. The mounting table-installed X-ray protection mechanism 42 may be detachably fixed to the mounting table 9 or the sample collection mechanism 13 with screws or the like. The X-ray protection mechanism 42 may be installed in the sample collection mechanism 13 as shown in FIG.

  Thus, the X-ray diagnostic apparatus 1 according to the application example 5 can reduce the exposure dose of the subject in the biopsy test.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

  DESCRIPTION OF SYMBOLS 1 ... X-ray diagnostic apparatus, 2 ... Imaging mechanism, 3 ... Mounting stand support mechanism, 4 ... X-ray tube support mechanism, 5 ... Support | pillar, 6 ... Shaft part, 7 ... X-ray tube, 8 ... High voltage generation part, 9 DESCRIPTION OF SYMBOLS ... Placement table, 10 ... X-ray detector, 11 ... Mounting surface, 12 ... Compression plate, 13 ... Sample collection mechanism, 14 ... Collection control part, 15 ... Collection drive part, 21 ... Image generation part, 22 ... Image processing 23: Reconstruction unit 24 ... Association unit 25 ... Input unit 26 ... Storage unit 27 ... Display unit 28 ... Interface unit 29 ... Imaging control unit 30 ... X-ray control unit 31 ... Drive control 32: System control unit 33: Irradiation field limiter 34: X-ray tube support mechanism drive unit 35 ... Mounting table support mechanism drive unit 41 ... Opening drive unit 42 ... X-ray protection mechanism

Claims (24)

An X-ray tube that generates X-rays;
An X-ray detector for detecting X-rays generated from the X-ray tube;
A mounting surface that is held between the X-ray tube and the X-ray detector and has a mounting portion for a subject and a mounting portion for a sample collected from the subject on the same plane. When,
A mounting table support mechanism for supporting the X-ray detector and the mounting surface;
An X-ray tube support mechanism for rotatably supporting the X-ray tube about a predetermined rotation axis;
An irradiation field limiter for limiting the solid angle of X-rays generated from the X-ray tube;
An irradiation field of the X-ray generated from the X-ray tube on the placement surface is selectively between the placement portion for the subject and the placement portion for the specimen on the placement surface. A switching unit for switching,
An X-ray diagnostic apparatus comprising: An X-ray tube that generates X-rays;
An X-ray detector for detecting X-rays generated from the X-ray tube;
A mounting surface that is held between the X-ray tube and the X-ray detector and has a mounting portion for a subject and a mounting portion for a sample collected from the subject on the same plane. When,
A mounting table support mechanism for supporting the X-ray detector and the mounting surface;
An X-ray tube support mechanism for rotatably supporting the X-ray tube about a predetermined rotation axis;
With
An X-ray diagnostic apparatus that selectively performs imaging of the subject placed on the placement portion for the subject and imaging of the specimen placed on the placement portion for the specimen. And
An X-ray diagnostic apparatus that protects the subject from X-rays during imaging of the specimen by a detachable shielding part. An image generator for generating an X-ray image based on an output signal from the X-ray detector;
When the irradiation field is aimed at the placement portion for the subject, the switching unit performs X-ray imaging for the placement portion for the subject, and the irradiation field When aiming at the placement portion for the specimen, execute X-ray imaging for the placement portion for the specimen,
The image generator generates an X-ray image of the placement portion for the subject when the irradiation field is aimed at the placement portion for the subject, and the irradiation field is When aiming at the placement portion for the specimen, an X-ray image relating to the placement portion for the specimen is generated,
The X-ray diagnostic apparatus according to claim 1.   The switching unit controls the angle for the rotation axis of the X-ray tube supported by the X-ray tube support mechanism and the size and shape of the opening of the irradiation field limiter, thereby mounting the subject. The X-ray diagnostic apparatus according to claim 1, wherein the irradiation field is selectively switched between a placement portion and a placement portion for the specimen.   The switching unit selectively switches the irradiation field between a placement portion for the subject and a placement portion for the specimen, triggered by a switching instruction from an examiner. The X-ray diagnostic apparatus according to Item 1. A sensing unit for sensing pressure applied to the mounting portion for the specimen;
The switching unit selectively switches the irradiation field between a placement portion for the subject and a placement portion for the specimen when the sensing portion senses a pressure equal to or higher than a predetermined value. ,
The X-ray diagnostic apparatus according to claim 1. An X-ray controller that controls X-ray conditions in X-ray imaging;
The switching unit controls the X-ray control unit to aim the irradiation field at the placement part for the subject and when aiming at the placement part for the specimen; To switch the X-ray condition,
The X-ray diagnostic apparatus according to claim 1.   The switching unit controls the X-ray tube support mechanism and the irradiation field limiter to change the irradiation field of the X-ray generated from the X-ray tube on the mounting surface, on the mounting surface. The X-ray diagnosis apparatus according to claim 1, wherein the X-ray diagnostic apparatus switches to the irradiation field including a placement portion for a subject and a placement portion for the specimen. The X-ray image relating to the placement portion for the subject and the X-ray image relating to the placement portion for the specimen are related to the placement portion for the specimen with respect to at least one of contrast and resolution. The X-ray diagnostic apparatus according to claim 3 , further comprising an image processing unit that switches image processing contents so that the X-ray image is higher.   The X-ray diagnostic apparatus according to claim 1, further comprising a sample collection mechanism for collecting the sample from the subject placed on the placement surface supported by the placement table support mechanism.   When the irradiation field is aimed at the placement portion for the subject, the switching unit controls the X-ray tube support mechanism, thereby controlling the X-ray at two different angles with respect to the subject. The X-ray diagnostic apparatus according to claim 1, wherein stereo imaging for performing imaging is executed. Wherein the X-ray image of the mounting portion for the subject and the X-ray image of the mounting portion for the specimen, further comprising an association unit for associating the same subject DICOM images, according to claim 3, wherein X-ray diagnostic equipment. The X-ray diagnostic apparatus according to claim 7 , further comprising a dose calculation unit that calculates an integrated exposure dose during X-ray imaging based on the X-ray condition. The X-ray diagnostic apparatus according to claim 13 , further comprising a display unit that displays the accumulated exposure dose.   The X-ray diagnostic apparatus according to claim 1, further comprising a volume calculation unit that calculates a volume of the specimen. The X-ray diagnostic apparatus according to claim 15 , further comprising a display unit that displays a volume of the specimen. An input section;
Based on the instruction of the examiner input at the input unit, the placement for the specimen is within a predetermined range of the X-ray image generated by X-ray imaging of the placement portion for the subject. The X-ray diagnostic apparatus according to claim 1, further comprising: a display unit that superimposes and displays an image obtained by cutting out a specimen region from an X-ray image generated by X-ray imaging for a placement portion. 18. The X-ray diagnosis according to claim 17 , wherein the predetermined range is set to a pixel range separated from a breast region in an X-ray image generated by X-ray imaging targeting a placement portion for the subject. apparatus. The X-ray diagnostic apparatus according to claim 18 , wherein the predetermined range is changed by an instruction by an examiner input at the input unit. And a display unit that displays a plurality of X-ray images generated by the stereo imaging and an X-ray image generated by X-ray imaging of the mounting portion for the specimen in a predetermined layout. The X-ray diagnostic apparatus according to claim 11 . An image generator for generating an X-ray image based on an output signal from the X-ray detector;
An X-ray controller for controlling X-ray conditions in X-ray imaging;
An image processing unit;
Further comprising a table support mechanism, the X-ray tube support mechanism, a drive control unit for controlling the irradiation field limiter,
The switching unit controls the X-ray control unit and the drive control unit to perform tomosynthesis imaging before the sample collection, and the image generation unit generates a plurality of X-ray images,
The switching unit controls the X-ray control unit and the drive control unit to perform tomosynthesis imaging after the sample collection, and the image generation unit generates a plurality of X-ray images,
The image processing unit performs image processing on the X-ray image before sampling and the X-ray image after sampling, and determines whether or not a cell to be sampled has been sampled.
The X-ray diagnostic apparatus according to claim 1.   The X-ray protection mechanism according to claim 1, further comprising an X-ray protection mechanism for shielding X-rays from the X-ray tube to the subject when the irradiation field is aimed at a placement portion for the specimen. Line diagnostic equipment.   The mounting part for the specimen has a first specimen mounting part and a second specimen mounting part, and the first specimen mounting part and the second specimen mounting part are for the subject. The X-ray diagnostic apparatus according to claim 1, wherein the X-ray diagnostic apparatus is provided apart from the mounting portion.   The X-ray diagnostic apparatus according to claim 1, wherein the subject is a breast.