JP6319738B2 - 虚血／再灌流障害に続くノーリフローの予防又は処置方法 - Google Patents

虚血／再灌流障害に続くノーリフローの予防又は処置方法 Download PDF

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JP6319738B2
JP6319738B2 JP2013518868A JP2013518868A JP6319738B2 JP 6319738 B2 JP6319738 B2 JP 6319738B2 JP 2013518868 A JP2013518868 A JP 2013518868A JP 2013518868 A JP2013518868 A JP 2013518868A JP 6319738 B2 JP6319738 B2 JP 6319738B2
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reflow
revascularization
phe
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JP2013531682A (ja
JP2013531682A5 (cg-RX-API-DMAC7.html
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ケネス ボロウ
ケネス ボロウ
ディー トラヴィス ウィルソン
ディー トラヴィス ウィルソン
ロバート エイ クロナー
ロバート エイ クロナー
シャロン ヘイル
シャロン ヘイル
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ステルス ペプチドズ インターナショナル インコーポレイテッド
ステルス ペプチドズ インターナショナル インコーポレイテッド
ハート インスティテュート グッド サマリタン ホスピタル
ハート インスティテュート グッド サマリタン ホスピタル
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
JP2013518868A 2010-07-09 2011-07-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法 Active JP6319738B2 (ja)

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Application Number Priority Date Filing Date Title
US36313310P 2010-07-09 2010-07-09
US36312910P 2010-07-09 2010-07-09
US61/363,129 2010-07-09
US61/363,133 2010-07-09
US41265510P 2010-11-11 2010-11-11
US61/412,655 2010-11-11
PCT/US2011/043424 WO2012006569A1 (en) 2010-07-09 2011-07-08 Methods for the prevention or treatment of no-reflow following ischemia/reperfusion injury

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JP2016136149A Division JP2016172781A (ja) 2010-07-09 2016-07-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法

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JP2013531682A JP2013531682A (ja) 2013-08-08
JP2013531682A5 JP2013531682A5 (cg-RX-API-DMAC7.html) 2014-08-21
JP6319738B2 true JP6319738B2 (ja) 2018-05-09

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JP2013518868A Active JP6319738B2 (ja) 2010-07-09 2011-07-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2016136149A Pending JP2016172781A (ja) 2010-07-09 2016-07-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2019000305A Pending JP2019052188A (ja) 2010-07-09 2019-01-04 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2020080135A Pending JP2020114880A (ja) 2010-07-09 2020-04-30 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2021181839A Pending JP2022012924A (ja) 2010-07-09 2021-11-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法

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JP2019000305A Pending JP2019052188A (ja) 2010-07-09 2019-01-04 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2020080135A Pending JP2020114880A (ja) 2010-07-09 2020-04-30 虚血／再灌流障害に続くノーリフローの予防又は処置方法
JP2021181839A Pending JP2022012924A (ja) 2010-07-09 2021-11-08 虚血／再灌流障害に続くノーリフローの予防又は処置方法

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US (2) US9345738B2 (cg-RX-API-DMAC7.html)
EP (3) EP4285994A3 (cg-RX-API-DMAC7.html)
JP (5) JP6319738B2 (cg-RX-API-DMAC7.html)
CN (4) CN103249423A (cg-RX-API-DMAC7.html)
CA (1) CA2804404C (cg-RX-API-DMAC7.html)
HK (1) HK1249428A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012006569A1 (cg-RX-API-DMAC7.html)

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HK1204988A1 (en) * 2012-02-22 2015-12-11 Stealth Peptides International, Inc. Methods and compositions for preventing or treating ophthalmic conditions
CA2869080C (en) * 2012-03-30 2020-09-01 Stealth Peptides International, Inc. Methods and compositions for the prevention and treatment neuropathy
EP3586864A1 (en) * 2013-05-14 2020-01-01 Stealth Biotherapeutics Corp Methods for the prevention or treatment of left ventricle remodeling
CA2916492A1 (en) 2013-06-27 2014-12-31 Stealth Biotherapeutics Corp Peptide therapeutics and methods for using same
US11724030B2 (en) * 2018-09-21 2023-08-15 Corflow Therapeutics Ag Method and apparatus for diagnosis and treatment of microvascular dysfunction
US10870678B2 (en) 2016-04-11 2020-12-22 Arcuate Therapeutics, Inc. Chiral peptides
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
AU2018336787B2 (en) 2017-09-19 2024-05-30 Corflow Therapeutics Ag Intracoronary characterization of microvascular obstruction (MVO) and myocardial infarction
IL305687B2 (en) * 2017-12-15 2024-12-01 Stealth Biotherapeutics Inc Mitochondria-targeting peptides
US11795196B2 (en) 2017-12-15 2023-10-24 Stealth Biotherapeutics Inc. Mitochondria-targeting peptides
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
CN113544138B (zh) * 2018-12-18 2024-10-29 隐形生物治疗公司 线粒体靶向肽
WO2020131283A1 (en) * 2018-12-18 2020-06-25 Stealth Biotherapeutics Corp. Analogs that target mitochondrial diseases
JPWO2020189593A1 (cg-RX-API-DMAC7.html) 2019-03-20 2020-09-24
RU2711414C1 (ru) * 2019-03-27 2020-01-17 Федеральное государственное бюджетное научное учреждение "Научный центр неврологии" (ФГБНУ НЦН) Способ прогнозирования асимптомного повреждения вещества головного мозга при ангиореконструктивных операциях на сонных артериях
JP7638265B2 (ja) 2019-07-24 2025-03-03 ステルス バイオセラピューティクス インコーポレイテッド 神経変性疾患の治療におけるペプチド模倣化合物（ｒ）－２－アミノ－ｎ－（（ｓ）－ｌ－（（（ｓ）－５－アミノ－ｌ－（３－ベンジル－１，２，４－オキサジアゾール－５－イル）ペンチル）アミノ）－３－（４－ヒドロキシ－２，６－ジメチルフェニル）－ｉ－オキソプロパン－２－イル）－５－グアニジノペンタンアミド
EP4792852A2 (en) 2020-05-22 2026-08-19 CorFlow Therapeutics AG Controlled flow infusion microvascular dysfunction diagnostic and therapy
JP7533970B2 (ja) * 2022-01-31 2024-08-14 株式会社ニューギン 遊技機
JP7478453B2 (ja) * 2022-01-31 2024-05-07 株式会社ニューギン 遊技機

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JP2016172781A (ja) 2016-09-29
US20130196921A1 (en) 2013-08-01
JP2013531682A (ja) 2013-08-08
CN105879008A (zh) 2016-08-24
EP2590664A4 (en) 2014-01-15
CN106620645A (zh) 2017-05-10
CA2804404A1 (en) 2012-01-12
EP2590664A1 (en) 2013-05-15
EP4285994A3 (en) 2024-01-17
JP2020114880A (ja) 2020-07-30
JP2019052188A (ja) 2019-04-04
US10322159B2 (en) 2019-06-18
EP2590664B1 (en) 2019-03-27
WO2012006569A1 (en) 2012-01-12
US9345738B2 (en) 2016-05-24
EP3539554A1 (en) 2019-09-18
CA2804404C (en) 2020-10-20
JP2022012924A (ja) 2022-01-17
CN103249423A (zh) 2013-08-14
EP4285994A2 (en) 2023-12-06
HK1249428A1 (zh) 2018-11-02
CN107569675A (zh) 2018-01-12
US20170087204A1 (en) 2017-03-30

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