JP6189114B2 - Powder processing equipment - Google Patents

Description

  The present invention relates to a granular material processing apparatus in which a granular material processing machine that performs processing such as mixing, drying, granulation, and coating of granular material is housed in a work chamber that is airtightly isolated from the external environment. About.

  For example, when processing granular materials such as highly pharmacologically active drugs or chemicals that are harmful to the human body, work that is airtightly isolated from the external environment to protect workers and prevent contamination of the external environment 2. Description of the Related Art A granular material processing apparatus is used in which a granular material processing machine is accommodated in a room and a required operation can be performed on the granular material processing machine from the outside of a working chamber.

  This type of powder processing equipment is often used for the development of micro drug discovery (research, experiment, manufacturing, analysis, measurement, etc.), and in order to process these powder materials, depending on the processing purpose Various powder processing machines are arranged inside the work chamber. For example, in Patent Document 1, a mounting portion having a mounting hole is provided on a wall surface of a working chamber, and a sub-device as a granular material processing machine having a modular mounting plate is installed while the mounting hole is airtightly closed. An isolator that can be attached to a device is disclosed.

  In the isolator of Patent Document 1, the mounting portion provided on the wall surface of the working chamber has a bolt fastening hole on the outer peripheral side of the mounting hole, and the mounting plate of the sub device is a screw hole corresponding to the bolt fastening hole of the mounting portion And an annular packing that can be in close contact with the wall surface of the working chamber at a position surrounding the mounting hole. Insert a part of the sub device into the mounting hole, and attach the mounting plate of the sub device to the wall surface of the work chamber via the annular packing, and then insert the bolt into the bolt fastening hole of the mounting plate and the screw hole of the mounting plate Then, the sub device can be attached to the attachment portion. Moreover, a sub apparatus can be removed from an attaching part and another sub apparatus can be mounted | worn with an attaching part.

Japanese Patent No. 4761497

  In the isolator disclosed in Patent Document 1, a part of the sub device is inserted into a mounting hole of a mounting portion provided on the wall surface of the work chamber, and the mounting plate of the sub device is brought into close contact with the wall surface of the work chamber via an annular packing. If the annular packing is deteriorated over time, the inside and outside of the working chamber are connected through the mounting holes, and the airtightness inside the working chamber cannot be maintained. . In addition, if the granular material enters between the inner side of the mounting plate of the sub device and the annular packing, or between the annular packing and the wall surface of the working chamber, contamination problems occur and cleaning work becomes difficult. Become.

  In addition, the position of the screw hole of the mounting plate of the sub device and the position of the bolt fastening hole of the mounting portion are aligned, and the work of fastening with the bolt is troublesome, and it takes time to attach and detach the sub device. In addition, in the case of a sub-device having a rotating body, since the weight becomes relatively large when the rotation drive source is included, the attaching / detaching operation becomes more troublesome.

  An object of the present invention is to provide a granular material processing apparatus in which a granular material processing machine having a rotating body is housed in a work chamber that is airtightly separated from an external environment. In addition to solving the problem of deterioration and contamination, the attachment / detachment work and the cleaning work are facilitated.

In order to solve the above-described problems, the present invention provides a working chamber that is airtightly isolated from the external environment, a powder processing machine that is housed in the working chamber and has a rotating body, and a working chamber. A rotational drive shaft that rotationally drives the rotating body of the powder processing machine, a rotational drive source provided outside the work chamber, and a shaft support portion that rotatably supports the rotational drive shaft inside the work chamber; , and a torque transmitting unit for transmitting the torque from the rotation drive source to a rotary drive shaft in a non-contact manner by a magnetic force through the wall of the working chamber, provided with a mutually different types plurality of said powder or granular material processing machine There is provided a granular material processing apparatus in which a rotating body of one granular material processing machine selected from a plurality of granular material processing machines is detachably mounted on a rotary drive shaft . By adopting such a configuration, the rotational drive source can be separated from the granular material processing machine and disposed outside the work room, so that the internal space of the work room can be effectively utilized. A mounting hole provided in the wall portion is not required, and a decrease in airtightness and contamination in the mounting portion can be prevented, and attachment / detachment work and cleaning work can be facilitated.

The said structure WHEREIN: The said several granular material processing machine contains the drum coating machine provided with the rotating drum as a rotary body in which the granular material to be processed is accommodated, for example , or the granular material to be processed is The mixing machine provided with the rotation container as a rotary body accommodated is included .

The rotating body of the particulate material processing machine, respectively, are detachably attached to the same rotary drive shaft. In other words, each of the particulate material processing machine, rotary drive shaft and the shaft support portion and the torque transmitting unit, and further share the rotational drive source, thereby, each granule processing machine and parts The weight is reduced, the attaching / detaching operation and the replacing operation are facilitated, and the cost of the entire apparatus is reduced.

  In the above configuration, a shaft support portion for rotatably supporting the rotation drive shaft inside the work chamber can be provided. The shaft support portion includes a bearing housing through which the rotation drive shaft is inserted, and the rotation drive shaft. However, it is possible to provide a structure that includes a bearing that supports the bearing housing rotatably and a support member that supports the bearing housing.

  In the above configuration, the torque transmission unit includes a first magnet plate coupled to the rotation drive shaft, a second magnet plate opposed to the first magnet plate via the wall of the work chamber, and coupled to the rotation drive source. It can be set as the structure provided with. Alternatively, the torque transmission unit may include a magnet plate coupled to a rotation drive shaft, and the rotation drive source may include a rotating magnetic field coil that faces the magnet plate via a wall of the work chamber.

  According to the present invention, in a granular material processing apparatus in which a granular material processing machine having a rotating body is housed inside a work chamber that is airtightly separated from the external environment, the airtightness in the mounting portion of the granular material processing machine is provided. It is possible to solve the problem of deterioration and contamination, and to facilitate attachment / detachment work and cleaning work.

It is the figure which looked at the granular material processing apparatus of embodiment from the front side. It is the figure which looked at the granular material processing apparatus of embodiment from the upper side. It is the figure which looked at the granular material processing apparatus of embodiment from the left side. It is the figure which looked at the granular material processing apparatus of embodiment from the right side. It is a longitudinal cross-sectional view which shows the periphery of a drum coating machine. It is a figure which shows the state which decomposed | disassembled the drum coating machine. It is a longitudinal cross-sectional view which shows the state which mounted | wore the rotational drive shaft with the mixer. It is a longitudinal cross-sectional view which shows the torque transmission part which concerns on other embodiment, and the peripheral part of a rotational drive source.

  As shown in FIGS. 1 to 4, the granular material processing apparatus according to this embodiment includes a work chamber 1 that is airtightly isolated from an external environment, one or more housed inside the work chamber 1, In the embodiment, a plurality of powder processing machines 2, 3, 4, 5 (or 6) are provided. The work chamber 1 is mounted on a gantry 7 provided with casters 7a, and one or more (seven in this embodiment) work in which work gloves (not shown) are airtightly attached to the front wall portion A thereof. A mouth 1a is provided. The work chamber 1 has at least a front wall portion A formed of a transparent material such as an acrylic plate so that the inside of the work chamber 1 can be visually recognized from the outside. The worker M inserts a hand from the work port 1a of the front wall portion A of the work box 1 and puts on a work glove attached to the work port 1a to perform a required work in the work chamber 1. be able to. The front wall A of the work chamber 1 can be opened and closed. Also, the RPT container 1b is airtightly connected to the left and right wall portions B and C of the work box 1, and the processing raw material is supplied from the RPT container 1b into the work chamber 1 by opening the door of the RPT container 1b. In addition, the processed product can be taken out from the working chamber 1 into the RPT container 1b. After the processed product is taken out from the work chamber 1 into the RPT container 1b, the door of the RPT container 1b is closed, and then the container portion of the RPT container 1b is removed from the door so that the work chamber 1 is completely closed. The processed product can be taken out to the outside.

  As shown in FIG. 2, on the side of the rear wall D of the work chamber 1, a plurality of powder processing machines 2, 3, 4, 5 (or 6), an air supply filter box 8 and an exhaust filter box 9. Etc. are attached. In this embodiment, the plurality of powder processing machines are a stirring and mixing granulator 2, a granulator 3, a drum coating machine (pan coating machine) 4, a fluidized bed processing machine 5, and a mixer (6), respectively. is there. As will be described later, in this embodiment, the drum coating machine 4 and the mixer (6) are interchangeable, and FIGS. 1 and 2 show a state in which the drum coating machine 4 is mounted. The stirring and mixing granulator 2 has a rotating stirring blade disposed at the bottom of the processing vessel, and the granulator 3 has, for example, a granule particle by a screen (sieve) provided with many holes of a predetermined size and a rotating impeller. The drum coating machine 4 forms a coating film on the surface of the granular particles by spraying and aerating the spray liquid on the granular particles accommodated in the rotary drum. The fluidized bed processing machine 5 performs processing such as granulation and coating by spraying the spray liquid while floating and flowing the powder particles in the processing container with the processing gas, and the mixer (6) The powder particles are put in a rotating container and mixed. As these powder processing machines 2, 3, 4, 5 (or 6), various known ones can be used.

  On the outer surface side of the rear wall portion D of the work chamber 1, a rear chamber 10 that is airtightly separated from the inside of the work chamber 1 is provided, and the rotational drive source 21 of the stirring and mixing granulator 2, the sizing The rotary drive source 31 of the machine 3, the rotary drive source 41 of the drum coating machine 4, the air supply filter box 8, and a part of the exhaust filter box 9 are respectively disposed inside the rear chamber 10. The stirring and mixing granulator 2, the granulator 3, the air supply filter box 8 and the exhaust filter box 9 are respectively attached to the mounting holes while closing the mounting holes provided in the rear wall portion D, and the fluidized bed The processor 5 is attached to an attachment member provided on the inner surface side of the rear wall portion D. A filter such as a hepa filter is accommodated inside the air supply filter box 8 and the exhaust filter box 9. The air supply filter box 8 is connected to the coating machine 4 and the fluidized bed processing machine 5 through an air supply pipe or the like inside the work chamber 1 and is connected to an air supply line (not shown) outside the work chamber 1. . The exhaust filter box 9 is connected to the coating machine 4 and the fluidized bed processing machine 5 through an exhaust pipe or the like inside the work chamber 1 and is connected to the exhaust blower through an exhaust pipe (not shown) outside the work chamber 1. (For example, accommodated in the gantry 7). In addition, in order to set and maintain the atmosphere in the work chamber 1 to a desired environment (for example, negative pressure), a supply / exhaust facility 11 for supplying and exhausting the work chamber 1 is provided.

  FIG. 5 shows the periphery of the drum coating machine 4 accommodated in the work chamber 1. The drum coating machine 4 includes a rotary drum 42 in which powder particles to be processed are accommodated, a casing 43 in which the rotary drum 42 is accommodated, and a spray of film solution or the like on the powder particles accommodated in the rotary drum 42. And a spray nozzle unit 44 for spraying the liquid. The rotary drum 42 is detachably attached to a rotary drive shaft 45 provided on the inner surface side of the rear wall portion D of the work chamber 1 by a fixing means, for example, a fixing bolt 45a. Thus, the shaft support 46 is rotatably supported. Torque from a rotation drive source (for example, a motor with a speed reducer) 41 disposed outside the work chamber 1 (rear chamber 10) is magnetically applied to the rotation drive shaft 45 via the rear wall D by the torque transmission unit 47. The force is transmitted in a non-contact manner by force, whereby the rotation drive shaft 45 and the rotary drum 42 connected thereto rotate.

In this embodiment, the torque transmission unit 47 is connected to the first magnet plate 47a connected to the rear end of the rotation drive shaft 45 and the output shaft of the rotation drive source 41, and is connected to the first magnet plate 47a and the rear wall portion D. And a second magnet plate 47b facing each other. For example, N magnetic pole permanent magnets and S magnetic pole permanent magnets are arranged in a predetermined pattern on the opposing surfaces of the first magnet plate 47a and the second magnet plate 47b, respectively. The torque of the rotational drive source 41 is transmitted to the rotational drive shaft 45 through the rear wall D in a non-contact manner. Such a torque transmission part 47 is also called a magnetic coupling or a magnet coupling, for example, what is described in Unexamined-Japanese-Patent No. 2012-57790, and what is manufactured and sold by B-Pro Corporation can be used. The rear wall portion D is formed of a nonmagnetic material such as acrylic, stainless steel, or aluminum at least at a portion interposed between the first magnet plate 47a and the second magnet plate 47b.

  In this embodiment, the shaft support portion 46 includes a bearing housing 46a through which the rotation drive shaft 45 is inserted, a bearing 46b that rotatably supports the rotation drive shaft 45 with respect to the bearing housing 46a, and the bearing housing 46a. And a support member 46c that supports the first wall portion, for example, the bottom wall portion E. A bearing retainer 46d is fixed to the rear end side of the bearing housing 46a, and a cover 46e covering the first magnet plate 47a is secured to the bearing retainer 46d with a screw. A bearing retainer 46f is fixed to the front end side of the bearing housing 46a, and a rear portion 43a of the casing 43 is fixed by a screw 43a1. A cover 46g that covers the second magnet plate 47b is also provided on the outer surface side of the rear wall D.

  The coating machine 4 of this embodiment can be disassembled in the manner shown in FIG. The casing 43 can be disassembled into a rear portion 43a, a main body portion 43b, and a front portion 43c. The main body 43b is provided with an air supply member 43b1 connected to the air supply pipe, an exhaust member 43b2 connected to the exhaust pipe, and a thumbscrew 43b3 used for attaching / detaching the rear part 43a. A powder material inlet 43c1 and a spray nozzle unit 44 are attached to the front portion 43c. A funnel-shaped charging member 43c2 is inserted into the charging port 43c1.

  In the state shown in FIG. 5, when the screw 43 a 1 that fixes the rear portion 43 a of the casing 43 to the bearing housing 46 a is removed and the fixing bolt 45 a that fixes the rotary drum 42 to the rotary drive shaft 45 is removed, the drum coating machine 4. Can be removed from the rotary drive shaft 45 (and the shaft support portion 46).

  When the drum coating machine 4 is removed from the rotary drive shaft 45 in the above-described manner, the rotary drive shaft 45 and the shaft support portion 46 remain in the work chamber 1 in the existing state. Further, the rotational drive source 41 is also left outside the work chamber 1 (the rear chamber 10) in the existing state. And after taking out the drum coating machine 4 to the exterior of the working chamber 1, the mixer 6 is mounted | worn with the aspect shown in FIG. The mixer 6 includes a rotating container 61 and a rotating shaft 62 fixed to the side of the rotating container 61. In the example shown in FIG. 7, the rotating shaft 62 of the rotating container 61 is ferruled to the rotation drive shaft 45. Joined by a joint 63. For this purpose, a ferrule joint portion 63 a is provided at the shaft end of the rotary shaft 62, and the ferrule joint portion 63 b is fixed to the shaft end of the rotary drive shaft 45 by a fixing bolt 45 a.

  In the state shown in FIG. 7, the mixer 6 can be removed from the rotary drive shaft 45 by removing the ferrule joint 63. And after taking out the mixer 6 to the exterior of the working chamber 1, the drum coating machine 4 can be mounted | worn with the aspect shown in FIG.

In another embodiment shown in FIG. 8, the torque transmission unit 47 includes a magnet plate 47 a similar to the first magnet plate of the above-described embodiment, but the rotational drive source 51 includes the magnet plate 47 a and the work chamber 1. A rotating magnetic field coil 52 is provided opposite to the rear wall portion D. The rotating magnetic field coil 52 is, for example, a coil portion in which an iron core 52b made of magnetic steel is provided inside a magnetic field coil 52a and arranged in a predetermined pattern in the circumferential direction, and a predetermined current is passed through the magnetic field coil 52. Thus, a rotating magnetic field is generated, and torque generated by the magnetic attractive force with the magnet plate 47a is transmitted to the rotary drive shaft 45 through the rear wall D in a non-contact manner.

DESCRIPTION OF SYMBOLS 1 Work chamber D Rear wall part 4 Drum coating machine 41 Rotation drive source 42 Rotation drum 45 Rotation drive shaft 45a Fixing bolt 46 Shaft support part 46a Bearing housing 46b Bearing 46c Support member 47 Torque transmission part 47a 1st magnet plate 47b 2nd magnet Plate 6 Mixer 61 Rotating container 63 Ferrule joint

Claims (6)

A work room that is airtightly isolated from the external environment;
A powder processing machine housed in the working chamber and having a rotating body;
A rotation drive shaft provided inside the working chamber and configured to rotationally drive the rotating body of the granular material processing machine;
A shaft support portion for rotatably supporting the rotation drive shaft inside the working chamber;
A rotational drive source provided outside the working chamber;
A torque transmission unit that transmits torque from the rotation drive source to the rotation drive shaft in a non-contact manner by magnetic force through the wall of the working chamber;
Provided with a plurality of powder processing machines of different types, the rotating body of one of the powder processing machines selected from the plurality of powder processing machines can be attached to and detached from the rotary drive shaft Powder processing equipment to be installed in the machine.   The shaft support portion includes a bearing housing through which the rotation drive shaft is inserted, a bearing that rotatably supports the rotation drive shaft with respect to the bearing housing, and a support member that supports the bearing housing. The granular material processing apparatus according to claim 1.   The granular material processing apparatus according to claim 1, wherein the plurality of granular material processing machines include a drum coating machine including a rotating drum as the rotating body in which the granular material to be processed is accommodated.   The said granular material processing machine is a granular material processing apparatus of Claim 1 containing the mixer provided with the rotation container as the said rotary body in which the granular material to be processed is accommodated.   The torque transmission unit is opposed to a first magnet plate provided on the rotation drive shaft, and the first magnet plate is opposed to the first magnet plate via a wall portion of the work chamber, and is provided on the rotation drive source. The granular material processing apparatus of Claim 1 provided with these. The torque transmission unit includes a magnet plate coupled to the rotation drive shaft, and the rotation drive source includes a rotating magnetic field coil facing the magnet plate through a wall of the work chamber. The granular material processing apparatus of description.

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