JP6162849B2 - Dialysate extraction device - Google Patents

Description

  The present invention is a dialysis fluid extraction means in which an inlet and an outlet through which the liquid can be circulated by being connected to a liquid flow path are formed, and a sampling port from which the circulated liquid can be collected is formed. The present invention relates to a dialysate extraction device including an opening / closing means that can be attached to and detached from the collection port of the dialysate extraction means and can open and close the collection port.

  Recently, a dialysis apparatus as a blood purification apparatus uses a dialysis solution to be supplied to a dialyzer during dialysis treatment (particularly, on-line HDF or on-line HF). Therefore, a technique for using the dialysate as a replacement liquid for the treatment of online HDF or online HF has been proposed. For example, in Patent Document 1, one end is connected to a dialysate outlet port (collecting port) formed at a predetermined site of the dialysate introduction line, and the other end is a blood circuit (arterial blood circuit or venous side blood circuit). ) And a replacement fluid pump disposed in the replacement fluid line is disclosed. In order to perform priming, blood return or replacement fluid (emergency replacement fluid) with such a dialysis device, the dialysate introduction line dialysate is supplied to the blood circuit (arterial blood circuit or venous blood circuit) by driving the replacement fluid pump. It comes to supply.

  Normally, a cap (opening / closing means) is detachable with respect to the dialysate outlet port. When the cap is removed and a replacement fluid line is connected, and when the replacement fluid line is not connected, a cap is attached and dialyzed. The dialysate flowing through the liquid introduction line is prevented from leaking outside. For example, in order to wash and disinfect a pipe through which dialysate flows, such as the dialysate introduction line and dialysate discharge line, the wash water and disinfectant water are circulated through the pipe with the cap attached to the sampling port. This prevents the wash water and disinfectant from leaking out.

  However, in the case where the cap seals tightly against the inner peripheral surface of the sampling port, there is a risk that cleaning water and disinfecting liquid will not circulate through the seal portion, resulting in insufficient cleaning and disinfection. It was. Therefore, conventionally, a cap is supposed to seal against the outer peripheral surface of the sampling port, and a configuration in which cleaning water or disinfecting liquid is brought to the inner peripheral surface of the sampling port has been proposed (for example, Patent Documents). 2 and 3). As a result, if a flow path for circulating the cleaning water or the disinfecting liquid from the cap is extended, the cleaning water or the disinfecting liquid will flow through the inside of the sampling port, and sufficient cleaning and disinfection can be achieved. it can.

JP 2004-313522 A JP 2003-93501 A JP 2009-207706 A

  However, in the conventional dialysate extraction device, the cleaning water or the disinfecting solution can be brought into the sampling port unless a flow path for flowing the cleaning water or the disinfecting solution from the cap (opening / closing means) is extended. There was a problem that was difficult. That is, even if a cap that simply seals against the outer peripheral surface of the sampling port is employed, only a single closed space is formed inside the sampling port. There is almost no distribution to the inside, and a separate flow path extending from the cap is required for distribution. When a separate flow path is extended, there is a problem that maintenance of the flow path is troublesome in addition to the necessity of handling the flow path.

  The present invention has been made in view of such circumstances, and a dialysis fluid extraction device capable of reliably cleaning and disinfecting the inside of a sampling port without extending a separate flow path from the opening / closing means. It is to provide.

The invention according to claim 1 is a dialysis fluid in which an inlet and an outlet that are connected to a liquid flow path and through which the liquid can be circulated are formed, and a sampling port that can collect the circulated liquid is formed In a dialysate extraction apparatus comprising an extraction means and an opening / closing means capable of opening and closing the collection port, the opening / closing means being attached to the collection port. In this state, a guide path for guiding the liquid introduced from the introduction port into the collection port and a discharge path for discharging the liquid guided by the guide path to the outlet port side are formed , and the dialysate The take-out means comprises pressure difference forming means for making the pressure of the liquid flowing toward the guide path out of the liquid introduced from the introduction port larger than the pressure of the liquid flowing toward the outlet port, and Pressure difference forming hand , Together comprising a flow path of the liquid flowing toward the sampling port from the inlet port, the flow passage, that the diameter of the channel is a tapered surface which gradually decreases toward the collection port side Features.

  According to a second aspect of the present invention, in the dialysate extraction device according to the first aspect, the opening / closing means includes a sealing means for sealing between the sampling port and an outer peripheral surface of the sampling port, and is attached to the sampling port. An inside of the sampling port is defined, and a defining means for forming the guide path and the discharge path is provided.

  According to a third aspect of the present invention, in the dialysate extraction device according to the second aspect, the defining means comprises a cylindrical member extending in the sampling port with the opening / closing means attached to the sampling port. The inside of the cylindrical member is the guide path, and the space between the outer peripheral surface of the cylindrical member and the inner peripheral surface of the sampling port is the discharge path.

  According to a fourth aspect of the present invention, in the dialysate extraction device according to the third aspect of the present invention, the tubular member is formed with a communication portion for communicating the guide path and the discharge path, A vortex or turbulent flow can be generated in the liquid flowing from the guide path to the discharge path.

  A fifth aspect of the present invention is the dialysate extraction device according to the first aspect, wherein the sampling port defines the guide path and the discharge path in a state where the opening / closing means is attached. To do.

  A sixth aspect of the present invention is the dialysate extraction device according to the fifth aspect, wherein the dialysate extraction means has a cylindrical outer peripheral wall portion covering the outer periphery of the sampling port, and the opening / closing means includes the outer periphery. Sealing means for sealing between the outer peripheral surface or the protruding end surface of the wall portion is provided.

According to a seventh aspect of the present invention, in the dialysate extraction device according to the sixth aspect, the inside of the sampling port is the guide path, and the outer peripheral surface of the sampling port and the inner peripheral surface of the outer peripheral wall portion The space is the discharge path.

The invention according to claim 8 is the dialysate extraction device according to any one of claims 1 to 7 , wherein the dialysate extraction means allows the liquid to flow out from the collection port and from the collection port. A check valve for blocking the inflow of the liquid is provided.

The invention according to claim 9 is the dialysate extraction device according to any one of claims 1 to 7 , wherein the dialysate extraction means is in a state where the opening / closing means is attached to the sampling port. In addition to permitting the flow of liquid in the guide path and the discharge path, there is provided a closing means for closing the sampling port when the sampling port is open.

A tenth aspect of the present invention is a blood purification apparatus comprising the dialysate extraction device according to any one of the first to ninth aspects.

According to the first aspect of the present invention, with the opening / closing means attached to the sampling port, the guide path for guiding the liquid introduced from the inlet into the sampling port, and the liquid guided by the guide path on the outlet side And a discharge channel for discharging to the inside of the sampling port without the need for extending a separate channel from the opening / closing means. Cleaning and disinfection can be performed reliably.
Further, the dialysate extraction means includes pressure difference forming means for making the pressure of the liquid flowing toward the guide path out of the liquid introduced from the introduction port larger than the pressure of the liquid flowing toward the outlet port. The cleaning water or the disinfecting liquid can be more reliably circulated through the guide path and the discharge path by the pressure difference generated by the pressure difference forming means.
Further, the pressure difference forming means has a flow passage for the liquid flowing from the introduction port toward the collection port, and the flow passage has a tapered surface in which the diameter of the flow path gradually decreases toward the collection port side. As a result, the pressure of the liquid flowing from the inlet to the guide path can be increased relative to the pressure of the liquid flowing from the inlet to the outlet, with respect to the guide path and the discharge path. Reliable circulation of cleaning water or disinfectant can be achieved.

  According to the invention of claim 2, the opening / closing means defines a sealing means for sealing between the outer peripheral surface of the sampling port and the inside of the sampling port in a state attached to the sampling port, the guide path and the discharge Since the defining means for forming the path is provided, the opening / closing means is provided with the defining means, and the defining means can circulate the washing water or the disinfectant solution through the guide path and the discharge path, and collect the sampling means. The inside of the mouth can be reliably cleaned and disinfected.

  According to the invention of claim 3, the defining means comprises a cylindrical member extending in the sampling port with the opening / closing means attached to the sampling port, and the inside of the cylindrical member serves as a guide path. In addition, since a discharge path is provided between the outer peripheral surface of the cylindrical member and the inner peripheral surface of the sampling port, the cleaning water or the disinfectant can be circulated well in the sampling port with a simple configuration. The mouth can be cleaned and disinfected more reliably.

  According to the invention of claim 4, the tubular member is formed with a communication portion for communicating the guide path and the discharge path, and the communication section is adapted to the liquid flowing from the guide path to the discharge path. Since vortex or turbulent flow can be generated, the inner peripheral surface of the sampling port can be more reliably cleaned or disinfected.

  According to the invention of claim 5, since the sampling port defines the guide path and the discharge path in a state where the opening / closing means is attached, the guide path and the discharge path are not provided in the opening / closing means. The cleaning water or the disinfecting liquid can be circulated through the sampling port, and the inside of the sampling port can be reliably cleaned and disinfected. Further, since the collection port has a function of defining the guide path and the discharge path in addition to the function of collecting the liquid, the configuration can be simplified by eliminating the need for a separate defining means.

  According to the invention of claim 6, the dialysate extraction means has a cylindrical outer peripheral wall portion covering the outer periphery of the sampling port, and the opening / closing means is sealed between the outer peripheral surface or the protruding end surface of the outer peripheral wall portion. Since the sealing means is provided, the guide path and the discharge path can be more reliably defined with the opening / closing means attached to the sampling port, and the flow of cleaning water or disinfectant can be improved. Can be done.

  According to the seventh aspect of the present invention, the inside of the sampling port is used as a guide path, and the gap between the outer peripheral surface of the sampling port and the inner peripheral surface of the outer peripheral wall portion is used as a discharge path. The washing water or the disinfecting liquid can be distributed more smoothly and satisfactorily through the path.

According to the invention of claim 8 , the dialysate extraction means includes the check valve that allows the liquid to flow out from the collection port and blocks the flow of liquid from the collection port. Etc. can be prevented from flowing from the sampling port into the fluid in the flow path connected to the tip of the liquid in the syringe or the replacement fluid line.

According to the invention of claim 9 , the dialysate extraction means allows the flow of liquid in the guide path and the discharge path when the open / close means is attached to the collection port, and when the collection port is open, Since the closing means for closing the sampling port is provided, it is possible to prevent the liquid from leaking out from the sampling port even when the opening / closing means is not attached to the sampling port.

According to the invention of claim 10 , the cleaning water or the disinfecting liquid can be circulated through the guide path and the discharge path, and the inside of the sampling port is cleaned and disinfected without extending a separate flow path from the opening / closing means. It is possible to provide a blood purification device that can reliably perform the above.

The schematic diagram which shows the blood purification apparatus with which the dialysate extraction apparatus of this invention is applied 1 is a schematic cross-sectional view showing a dialysate extraction device (a state in which an opening / closing means is attached to a sampling port) according to a first embodiment of the present invention Cross-sectional schematic diagram showing a cap (opening / closing means) in the dialysate extraction device Schematic cross-sectional view showing a communicating portion formed in a cylindrical member as a defining means in the dialysate extraction device Cross-sectional schematic diagram showing a state in which a syringe is connected to the sampling port of the dialysate extraction device Schematic cross-sectional view showing a dialysate extraction device according to the first reference example (with an opening / closing means attached to the sampling port) Sectional schematic diagram showing the dialysate extraction device (with the opening and closing means attached to the sampling port) according to the second reference example Sectional schematic diagram showing a dialysate extraction device according to the third reference example (with an opening / closing means attached to the sampling port) Cross-sectional schematic diagram showing a state in which a syringe is connected to the sampling port of the dialysate extraction device Sectional schematic diagram which shows the communication part formed in the cylindrical member as a definition means in the dialysate extraction apparatus which concerns on another reference example . Sectional schematic diagram showing a dialysate extraction device according to a fourth reference example (with an opening / closing means attached to the sampling port) Cross-sectional schematic diagram showing a state in which a syringe is connected to the sampling port of the dialysate extraction device Sectional schematic diagram showing a dialysate extraction device according to a fifth reference example (with an opening / closing means attached to the sampling port) Cross-sectional schematic diagram showing a state in which a syringe is connected to the sampling port of the dialysate extraction device Cross-sectional schematic diagram showing the sampling port in the open state in the dialysate extraction device Sectional schematic diagram which shows the dialysate extraction apparatus (state which attached the opening-and-closing means to the collection port) which concerns on the 2nd Embodiment of this invention. Cross-sectional schematic diagram showing a state where the opening / closing means is removed from the sampling port of the dialysate extraction device Schematic cross-sectional view showing a state in which the shaft member 33 is rotated around the shaft member 33 after removing the opening / closing means from the sampling port of the dialysate extraction device Schematic cross-sectional view showing a state where the shaft member 35 is rotated after the opening / closing means is removed from the sampling port of the dialysate extraction device Sectional schematic diagram which shows the dialysate extraction apparatus (state which attached the opening-and-closing means to the collection port) which concerns on the 3rd Embodiment of this invention. Cross-sectional schematic diagram showing a cap (opening / closing means) in the dialysate extraction device Sectional schematic diagram showing dialysate extraction means (with the opening and closing means removed) in the dialysate extraction device Cross-sectional schematic diagram showing connection means connectable to the sampling port of the dialysate extraction device Sectional schematic diagram showing dialysate extraction means (state with opening / closing means removed and connection means connected) in the same dialysate extraction device

Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dialysate extraction device according to the present embodiment is disposed in a blood purification device used in blood purification treatment (hemodialysis treatment), and can collect dialysate. As shown in FIG. 1, the applied blood purification apparatus includes a blood circuit in which an arterial blood circuit 2 and a venous blood circuit 3 are connected to a dialyzer 1 (blood purifier), a dialysate introduction line L1, and a dialysate. It is mainly composed of a dialyzer body B having a discharge line L2.

  The dialyzer 1 is for purifying blood, and is connected to the arterial blood circuit 2 and the venous blood circuit 3 constituting the blood circuit, and to the dialysate introduction line L1 and the dialysate discharge line L2, respectively. The patient's blood collected from the arterial puncture needle a is circulated extracorporeally in the blood circuit, purified and drained by the dialyzer 1, and then returned to the patient from the venous puncture needle b. Yes. In addition, the code | symbols 5 and 6 in the figure have shown the air trap chamber.

  In addition, a dual pump 7 is connected to the dialysate introduction line L1 and the dialysate discharge line L2 to supply dialysate adjusted to a predetermined concentration to the dialyzer 1 and discharge it from the dialyzer 1. Further, a plurality of bypass lines and electromagnetic valves are disposed in arbitrary positions in the dialyzer main body B, and a water removal pump 8 is connected to the bypass line for bypassing the dual pump 7.

  In order to disinfect or clean the piping in the dialyzer main body B, the tips of the dialysate introduction line L1 and the dialysate discharge line L2 are removed from the dialyzer 1, and the tips are connected to each other by a coupler or the like, for example. After short-circuiting, a disinfectant solution (hot water or disinfectant solution) or washing water (clean water) is introduced from the outside of the dialyzer body B (for example, dialysate supply device), and the liquid in the pipe in the dialyzer body B ( It is performed by substituting with dialysate. For example, by branching the flow path from the dialysate discharge line L2 and inserting the tip of the flow path into a tank containing the disinfectant solution, the disinfectant solution is introduced into the pipe from the tank and replaced. May be.

  Here, the dialysate extraction device according to the first embodiment of the present invention is connected to the dialysate introduction line L1. As shown in FIGS. 2 to 5, the dialysate extraction device according to the present embodiment is connected to a dialysate introduction line L1 (liquid flow path) and can introduce an introduction port 9a through which the liquid (dialysis solution) can flow. The outlet 9b is formed, and the dialysate extraction means 9 is formed with a sampling port 9c capable of collecting the circulated liquid, and is removable from the sampling port 9c of the dialysate extraction means 9, And a cap 10 as an opening / closing means capable of opening and closing the sampling port 9c.

  More specifically, the dialysate extraction means 9 is configured such that a dialysate introduction line L1 is connected to each of the inlet 9a and outlet 9b, and the dialysate can be circulated therein. The flow path through which the dialysate flows from the inlet 9a toward the outlet 9b) is bent approximately 90 degrees at the branch portion P and extends in an L shape, and the sampling port 9c is connected to the inlet 9a. It is formed so as to be located on substantially the same straight line. In the present embodiment, the site where the sampling port 9c is formed is a separate member from the site where the inlet 9a and the outlet 9b are formed, and they are connected via a seal member e. However, it may be an integral part.

  Further, the sampling port 9c is connected to connecting means such as a syringe S (see FIG. 5) or a connecting line (a replacement fluid line whose tip is connected to a predetermined part of the blood circuit) with the cap 10 (opening / closing means) removed. A male screw portion 9ca is formed on the outer peripheral surface. The male screw portion 9ca is formed so as to mesh with the female screw portion 10a of the cap 10 or a lock ring formed at the proximal end of the connection line, and can be fixed by screwing the cap 10 or the lock ring. ing.

  The cap 10 as an opening / closing means is a so-called sample port that can connect the distal end portion Sa of the syringe S or the proximal end of the connection line, and as shown in FIG. The inside of the collection port 9c is defined in a state of being attached to the collection port 9c and the sealing means 11 comprising an O-ring or the like that is sealed with a liquid (dialysis solution, disinfection solution, etc.) introduced from the introduction port 9a. A defining means 12 is provided that forms a guide path α that guides into the collection port 9c and a discharge path β that discharges the liquid guided by the guide path α to the outlet 9b side.

  More specifically, the defining means 12 is composed of a cylindrical member extending in the sampling port 9c with the cap 10 attached to the sampling port 9c, and the inside of the cylindrical member is connected to the guide path α. In addition, the discharge path β is defined between the outer peripheral surface of the cylindrical member and the inner peripheral surface 9cb of the sampling port 9c. As shown in FIGS. 3 and 4, the cylindrical member constituting the defining means 12 is formed with a pair of communicating portions 12 a for penetrating the inside and outside to communicate the guide path α and the discharge path β. The liquid guided to the guide path α can flow out to the discharge path β side through the communication portion 12a.

  In the present embodiment, the defining means 12 is constituted by a cylindrical member. However, any other member may be used as long as it is a cylindrical member that can define the guide path α and the discharge path β. May be. Furthermore, in the present embodiment, the communication portion 12a is a hole formed at a predetermined position of the cylindrical member constituting the defining means 12, but the communication path α and the discharge path β can be communicated with each other. If there is, it may be a notch.

  On the other hand, the dialysate extraction means 9 is formed with a connection path γ for connecting the discharge path β and the flow path on the outlet 9b side from the branch portion P. Thereby, the liquid that has flowed from the inlet 9a toward the sampling port 9c via the branch portion P is discharged from the outlet 9b through the guide path α, the outlet path β, and the connecting path γ, and branched from the inlet 9a. The liquid that flows toward the outlet 9b through the part P can join and flow out of the outlet 9b.

  Here, the dialysate extraction means 9 according to the present embodiment makes the pressure of the liquid flowing toward the guide path α out of the liquid introduced from the inlet 9a larger than the pressure of the liquid flowing toward the outlet 9b. Pressure difference forming means 13 is provided. The pressure difference forming means 13 is disposed in the vicinity of the branch portion P of the dialysate extraction means 9 and has a liquid flow path 13a flowing from the inlet 9a toward the collection port 9c, and the flow path 13a. Is a tapered surface in which the diameter of the flow path gradually decreases toward the sampling port 9c side (right side in FIG. 2). As a result, the pressure of the liquid flowing from the inlet 9a toward the collection port 9c can be relatively increased with respect to the pressure of the liquid flowing from the inlet 9a toward the outlet 9b.

  According to the first embodiment, the cap 10 defines the inside of the sampling port 9c in a state of being attached to the sampling port 9c and the sealing means 11 that seals between the outer peripheral surface of the sampling port 9c. The defining means 12 forms a guide path α for guiding the liquid introduced from the inlet 9a into the sampling port 9c and a discharge path β for discharging the liquid guided by the guide path α to the outlet 9b. Since the cleaning water or the disinfecting liquid can be circulated inside the sampling port 9c via the guide path α and the discharge path β, the sampling port 9c can be provided without extending a separate channel from the cap 10. Internal cleaning and disinfection can be ensured.

  The defining means 12 is composed of a cylindrical member extending in the sampling port 9c with the cap 10 attached to the sampling port 9c, and the inside of the cylindrical member is used as a guide path α. Since the space between the outer peripheral surface of the cylindrical member and the inner peripheral surface 9cb of the sampling port 9c is the discharge path β, the cleaning water or the disinfectant can be favorably distributed in the sampling port 9c with a simple configuration. In addition, the inside of the sampling port 9c (particularly the inner peripheral surface 9cb) can be more reliably cleaned and disinfected.

  Furthermore, the dialysate extraction means 9 makes the pressure of the liquid flowing toward the guide path α (that is, the collection port 9c) out of the liquid introduced from the inlet 9a larger than the pressure of the liquid flowing toward the outlet 9b. Since the pressure difference forming means 13 is provided, the cleaning water or the disinfecting liquid can be more reliably circulated through the guide path α and the discharge path β by the pressure difference generated by the pressure difference forming means 13.

  In particular, according to the present embodiment, the pressure difference forming means 13 has a flow passage for liquid flowing from the introduction port 9a toward the collection port 9c, and the flow passage has a diameter of the flow channel. Since the tapered surface gradually decreases toward the 9c side, a pressure difference can be provided between the guide path α and the discharge path β. Distribution of disinfectant can be achieved.

  Furthermore, since the introduction port 9a and the collection port 9c in the dialysate extraction means 9 are formed on substantially the same straight line, the liquid introduced from the introduction port 9a flows directly toward the collection port 9c. The cleaning water or the disinfecting liquid can be circulated through the guide path α and the discharge path β reliably and well, and the cleaning and disinfection inside the sampling port 9c can be performed more reliably.

Next, the dialysate extraction device according to the first reference example will be described.
The dialysate extraction apparatus according to this reference example is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1 as in the first embodiment. As shown in FIG. An inlet 14a and outlet 14b that are connected to the line L1 (liquid flow path) and can flow the liquid (dialysate) are formed, and a sampling port 14c that can collect the flowed liquid is formed. The dialysis fluid extraction means 14 and the cap 10 as an opening / closing means that can be attached to and detached from the collection port 14c of the dialysis fluid extraction means 14 and can open and close the collection port 14c.

  The sampling port 14c is formed with a male screw portion 14ca that can be screwed with the female screw portion 10a of the cap 10 on the outer peripheral surface thereof, and the defining means 12 is in the state where the cap 10 is attached to the sampling port 14c. It consists of a cylindrical member extending in the sampling port 14c, and the inside of the cylindrical member is used as a guide path α, and between the outer peripheral surface of the cylindrical member and the inner peripheral surface 14cb of the sampling port 14c. The discharge path β. In addition, the same code | symbol is attached | subjected to the component similar to 1st Embodiment, and those detailed description is abbreviate | omitted.

  A guide member 15 is disposed on the side of the collection port 14c near the branching portion P in the dialysate extraction means 14. The guide member 15 has a flow path 15a extending toward the guide path α, and the liquid introduced from the introduction port 14a is guided into the guide path α by the flow path 15a. . The flow path 15a may have a tapered surface whose diameter gradually decreases toward the sampling port 14c as in the first embodiment.

Here, in the present reference example , a pressure difference forming means including an orifice 14d for reducing the pressure by restricting the flow of liquid from the inlet 14a to the outlet 14b is formed. The orifice 14d is a part of the flow path from the branch portion P toward the outlet 14b and is formed on the upstream side (that is, the branch portion P side) from the junction with the connecting path γ. Of the liquid introduced from the inlet 14a, the pressure of the liquid flowing toward the guide path α is configured to be relatively greater than the pressure of the liquid flowing toward the outlet 14b.

However, in this reference example , the inlet 14a and the outlet 14b are formed on substantially the same straight line, and are approximately 90 degrees with respect to the flow path constituted by the inlet 14a and the outlet 14b. Although the collection port 14c is formed at the position, the introduction port 14a and the collection port 14c in the dialysate extraction means 14 may be formed on substantially the same straight line as in the first embodiment. Further, the tip of the flow path 15 a of the guide member 15 may be set so as to contact the tip of the defining means 12.

According to the present reference example , the pressure difference forming means includes the orifice 14d for reducing the pressure by reducing the flow of the liquid from the inlet 14a to the outlet 14b. Thus, it is possible to provide a reliable flow of cleaning water or disinfecting liquid to the guide path α and the discharge path β.

Next, a dialysate extraction device according to a second reference example will be described.
The dialysate extraction apparatus according to this reference example is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1 as in the first embodiment. As shown in FIG. An inlet 16a and an outlet 16b that are connected to the line L1 (liquid flow path) and can flow the liquid (dialysate) are formed, and a sampling port 16c that can collect the flowed liquid is formed. The dialysis fluid extraction means 16 and the cap 10 as an opening / closing means that can be attached to and detached from the sampling port 16c of the dialysis fluid extraction means 16 and can open and close the sampling port 16c.

  The sampling port 16c is formed with a male screw portion 16ca that can be screwed with the female screw portion 10a of the cap 10 on the outer peripheral surface thereof, and the defining means 12 is in a state where the cap 10 is attached to the sampling port 16c. It consists of a cylindrical member extending in the sampling port 16c, the inside of the cylindrical member is a guide path α, and the space between the outer peripheral surface of the cylindrical member and the inner peripheral surface 16cb of the sampling port 16c. The discharge path β. In addition, the same code | symbol is attached | subjected to the component similar to 1st Embodiment, and those detailed description is abbreviate | omitted.

  A guide member 17 is disposed on the side of the collection port 16c near the branch portion P in the dialysate extraction means 16. The guide member 17 is formed with a flow path 17a extending toward the guide path α, and the liquid introduced from the introduction port 16a is guided into the guide path α by the flow path 17a. . The channel 17a may have a tapered surface whose diameter gradually decreases toward the sampling port 16c as in the first embodiment.

Here, in this reference example , a pressure difference forming means having a venturi shape 16d for reducing the pressure by restricting the flow of the liquid from the inlet 16a to the outlet 16b is formed. The venturi shape 16d is a part of the flow path from the branch portion P toward the outlet 16b and is formed at the junction with the connecting path γ. The liquid introduced from the inlet 16a by the venturi shape 16d. Among these, the pressure of the liquid flowing toward the guide path α is configured to be relatively larger than the pressure of the liquid flowing toward the outlet 16b.

According to the present reference example , the pressure difference forming means is composed of the venturi shape 16d for reducing the pressure by reducing the flow of the liquid from the inlet 16a to the outlet 16b, so that the pressure difference is directed from the inlet 16a to the outlet 16b. The pressure of the flowing liquid can be made relatively small with respect to the pressure of the liquid flowing from the introduction port 16a toward the sampling port 16c, and reliable cleaning water or disinfecting liquid can be supplied to the guide path α and the discharge path β. Distribution is possible.

Next, a dialysate extraction device according to a third reference example will be described.
The dialysate extraction apparatus according to this reference example is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1 as in the first embodiment. As shown in FIG. An inlet 18a and an outlet 18b that are connected to the line L1 (liquid flow path) and can flow the liquid (dialysate) are formed, and a sampling port 18c that can collect the flowed liquid is formed. And a cap 10 as an opening / closing means that can be attached to and detached from the collection port 18c of the dialysate extraction unit 18 and can open and close the collection port 18c.

  The sampling port 18c is formed with a male screw portion 18ca that can be screwed to the female screw portion 10a of the cap 10 on the outer peripheral surface thereof, and the defining means 12 is in a state where the cap 10 is attached to the sampling port 18c. It consists of a cylindrical member extending in the sampling port 18c, and the inside of the cylindrical member is used as a guide path α, and between the outer peripheral surface of the cylindrical member and the inner peripheral surface 18cb of the sampling port 18c. The discharge path β. In addition, the same code | symbol is attached | subjected to the component similar to 1st Embodiment, and those detailed description is abbreviate | omitted.

Here, in this reference example , the pressure difference is made up of the interlocking member 19 that operates according to the attachment of the cap 10 to the sampling port 18c and can reduce the pressure by reducing the flow of the liquid from the inlet 18a to the outlet 18b. Forming means are formed. The interlocking member 19 is slidable in the branch portion P and is always biased toward the sampling port 18c by the spring 20. The interlocking member 19 is formed with a flow path 19a extending toward the guide path α, and the liquid introduced from the introduction port 18a is guided into the guide path α by the flow path 19a. Yes. The flow path 18a may have a tapered surface whose diameter gradually decreases toward the sampling port 18c as in the first embodiment.

  However, when the cap 10 is attached to the sampling port 18c, the defining means 12 of the cap 10 presses the interlocking member 19, so that the interlocking member 19 slides against the urging force of the spring 20, and the branch portion P Therefore, a part of the flow path from to the outlet 18b is blocked (see FIG. 8). As a result, the portion blocked by the interlocking member 19 acts as an orifice, and the flow of liquid from the inlet port 18a toward the outlet port 18b is throttled to reduce the pressure.

  On the other hand, as shown in FIG. 9, in the state where the cap 10 is removed and, for example, the distal end portion Sa of the syringe S is connected to the sampling port 18c (the same applies to the state where the sampling port 18c is opened and none of them are connected). The interlocking member 19 is positioned on the sampling port 18c side by the urging force of the spring 20, so that the flow path from the branching portion P to the outlet port 18b is not blocked and the operation of the orifice does not occur.

According to this reference example , the pressure difference forming means operates in accordance with the attachment of the cap 10 to the sampling port 18c, and the interlocking member 19 that can reduce the pressure by restricting the flow of liquid from the inlet 18a to the outlet 18b. Therefore, only when the cap 10 is attached to the collection port 18c, the pressure of the liquid flowing from the introduction port 18a to the discharge port 18b is relative to the pressure of the liquid flowing from the introduction port 18a to the collection port 18c. The flow of the cleaning liquid or the disinfecting liquid to the guide path α and the discharge path β can be favorably performed.

In the first embodiment and the first to third reference examples , the defining means 12 is composed of a cylindrical member that extends in the sampling port with the cap 10 attached to the sampling port. The inside of the member is a guide path α, and the discharge path β is between the outer peripheral surface of the cylindrical member and the inner peripheral surface of the sampling port. As shown in the figure, a communication part 12a for communicating the guide path α and the discharge path β is formed, but instead of this, as shown in FIG. The defining means 12 'may be offset from each other with respect to the cross section, and may generate vortex or turbulence in the liquid flowing from the guide path α to the discharge path β.

  In this way, the tubular member constituting the defining means 12 ′ is formed with a communication portion 12′a for communicating the guide path α and the discharge path β, and the communication portion 12′a If the vortex or turbulent flow is generated in the liquid flowing from the guide path α to the discharge path β, the inner peripheral surface of the sampling port can be more reliably cleaned or disinfected. In addition to the one in which the communication portion 12′a is offset with respect to the cross section of the cylindrical member, the hole is formed in a spiral shape or notched from the guide path α toward the discharge path β, thereby discharging from the guide path α. A vortex or turbulent flow may be generated for the liquid flowing in the path β.

Next, a dialysate extraction apparatus according to a fourth reference example will be described.
The dialysate extraction apparatus according to this reference example is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1 as in the first embodiment. As shown in FIG. An inlet 21a and an outlet 21b that are connected to the line L1 (liquid flow path) and can flow the liquid (dialysate) are formed, and a sampling port 21c that can collect the flowed liquid is formed. And a cap 10 as an opening / closing means that can be attached to and detached from the sampling port 21c of the dialysate extracting unit 21 and can open and close the sampling port 21c.

  The sampling port 21c is formed with a male screw portion 21ca that can be screwed with the female screw portion 10a of the cap 10 on the outer peripheral surface thereof, and the defining means 12 is in a state where the cap 10 is attached to the sampling port 21c. It consists of a cylindrical member extending in the sampling port 21c, and the inside of the cylindrical member is used as a guide path α, and between the outer peripheral surface of the cylindrical member and the inner peripheral surface 21cb of the sampling port 21c. The discharge path β. In addition, the same code | symbol is attached | subjected to the component similar to 1st Embodiment, and those detailed description is abbreviate | omitted.

Here, the dialysate extraction means 21 according to the present reference example allows a liquid to flow out from the collection port 21c and blocks the flow of liquid from the collection port 21c, and the check valve G And a sliding member 22 that can slide in the vicinity of the branch portion P according to the attachment of the cap 10 to the sampling port 21c, and a spring 23 that constantly biases the sliding member 22 toward the sampling port 21c. And is configured.

  As in the first embodiment, the sliding member 22 is formed in communication with the flow path 22a having a tapered surface whose diameter gradually decreases toward the sampling port 21c and the reverse of the flow path 22a. An accommodation space 22b that accommodates the stop valve G, and a flow path 22c that allows the accommodation space 22b and the guide path α to communicate with each other are formed. The flow path 22a, the accommodation space 22b, and the flow path 22c form an introduction port. The liquid introduced from 21a is guided into the guide path α.

In addition, as shown in FIG. 12, the dialysate extraction means 21 according to the present reference example is connected to the sampling port 21c with the syringe S (or the connection means such as the connection line) connected to the guide path α. A seal member 24 that allows the flow of the liquid and blocks the sampling port 21c and the flow path inside the dialysate extraction means 21 is provided. That is, when the cap 10 is removed from the sampling port 21c and, for example, the syringe S and the connecting means are connected, the sliding member 22 is pressed against the sampling port 21c by the biasing force of the spring 23, and the sliding member The one piece 22ca of 22 and the seal member 24 are in close contact with each other and are closed.

  However, the check valve G allows the flow of liquid from the flow path 22a to the flow path 22c and restricts the flow of liquid from the flow path 22c to the flow path 22a. When connected to the port 21c, the collection of the liquid by the syringe S or the like is maintained well, and the liquid in the flow path (blood circuit or the like) connected to the tip of the liquid in the syringe S or the replacement fluid line is collected. Inflow from 21c can be avoided.

Next, a dialysate extraction device according to a fifth reference example will be described.
The dialysate extraction apparatus according to this reference example is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1 as in the first embodiment. As shown in FIGS. An inlet 25a and an outlet 25b that are connected to the liquid introduction line L1 (liquid flow path) and can flow the liquid (dialysis liquid) are formed, and a sampling port 25c that can collect the flowed liquid is formed. The formed dialysate extraction means 25 and the cap 10 as an opening / closing means that can be attached to and detached from the collection port 25c of the dialysate extraction means 25 and can open and close the collection port 25c.

  The sampling port 25c is formed with a male screw portion 25ca that can be screwed with the female screw portion 10a of the cap 10 on the outer peripheral surface thereof, and the defining means 12 is in a state where the cap 10 is attached to the sampling port 25c. It consists of a cylindrical member extending in the sampling port 25c, and the inside of the cylindrical member serves as a guide path α, and the space between the outer peripheral surface of the cylindrical member and the inner peripheral surface 25cb of the sampling port 25c. The discharge path β. In addition, the same code | symbol is attached | subjected to the component similar to 1st Embodiment, and those detailed description is abbreviate | omitted.

Here, when the cap 10 is attached to the collection port 25c, the dialysate extraction means 25 according to this reference example allows the flow of liquid in the guide path α and the discharge path β and opens the collection port 25c. In the state, it has a closing means for closing the sampling port 25c. Specifically, the closing means according to the present reference example can slide in the vicinity of the branch portion P, and can slide within the sliding member 26 having the seal member 28 therein and the sliding member 26. An interlocking member 27 having communication holes 27a and 27b formed in predetermined portions, a spring 29 that constantly biases the sliding member 26 toward the sampling port 25c, and a spring 30 that constantly biases the interlocking member 27 toward the sampling port 25c. And a sealing member 31.

  In addition, flow paths through which liquid can be circulated are formed inside the sliding member 26 and the interlocking member 27, respectively, and connection means such as a syringe S or a connection line is provided with the cap 10 attached to the sampling port 25c. In the connected state, as shown in FIGS. 13 and 14, the flow paths are connected via communication holes 27 a and 27 b. The seal members 28 and 31 are formed with seal portions 28a and 31a. When the seal portion 28a comes into contact with the end of the interlocking member 27, the seal member 28 can seal the seal member 28 and 31. The portion 31a is configured to be able to be sealed by the seal member 31 by contacting the end surface of the sliding member 26.

  For example, when the cap 10 is attached to the sampling port 25c, as shown in FIG. 13, the defining means 12 of the cap 10 is configured to press the interlocking member 27, and the pressed interlocking member 27 is a spring. Moves against 30 urging forces. When the compression limit of the spring 30 is reached by a stopper mechanism or the like (not shown), the moving force of the interlocking member 27 is transmitted to the sliding member 26, and the sliding member 26 moves in the same direction together with the interlocking member 27. As a result, the communication holes 27a and 27b formed in the interlocking member 27 are opened, and the sealing members 28 and 31 are not sealed, so the liquid flowing from the inlet 25a toward the sampling port 25c is After passing through the flow paths inside the sliding member 26 and the interlocking member 27, it reaches the guide path α in the defining means 12, flows through the discharge path β via the communication portion 12a, and is discharged toward the outlet 25b.

  On the other hand, in a state where the syringe S is attached to the sampling port 25c (the same applies to a state where connection means such as a connection line is connected), the distal end portion Sa of the syringe S presses the interlocking member 27 as shown in FIG. Thus, the pressed interlocking member 27 moves against the biasing force of the spring 30. At this time, since the interlocking member 27 does not reach the compression limit of the spring 30 by a stopper mechanism or the like (not shown), the sliding member 26 does not move in the same direction, and the sealing portion 31a of the sealing member 31 moves to the sliding member 26. The seal is in contact with the end face of the seal. As a result, the communication holes 27a and 27b formed in the interlocking member 27 are opened, and the sealing member 31 is sealed while the sealing member 28 is not sealed, so that the inlet 25a leads to the sampling port 25c. The liquid flowing toward the syringe S flows toward the syringe S after passing through the flow paths inside the sliding member 26 and the interlocking member 27.

  Further, when the cap 10 or the syringe S or the like is not attached to the sampling port 25c, that is, in the open state, no pressing force is applied to the interlocking member 27 as shown in FIG. 27 is positioned on the sampling port 25c side by the urging force of the springs 29 and 30, and sealing by the seal members 28 and 31 is achieved. Thereby, when the sampling port 25c is in the open state, the sampling port 25c can be closed by the closing means.

According to this reference example , when the cap 10 is attached to the collection port 25c, the dialysate extraction means 25 allows the flow of liquid in the guide path α and the discharge path β, and the collection port 25c is open. In this case, since the closing means for closing the sampling port 25c is provided, it is possible to prevent the liquid from leaking outside from the sampling port 25c even when the cap 10 is not attached to the sampling port 25c. it can.

Next, a dialysate extraction device according to a second embodiment of the present invention will be described.
As in the first embodiment, the dialysate extraction apparatus according to this embodiment is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1, and as shown in FIGS. The liquid extraction means 9, the cap 10 'serving as an opening / closing means capable of opening and closing the collection port 9c, which can be attached to and detached from the collection port 9c of the dialysate extraction means 9, and the closed state of the cap 10' maintained Holding means 32 that can be used. In addition, since the dialysate extraction means 9 applied by this embodiment is set as the same structure as 1st Embodiment, detailed description is abbreviate | omitted.

  As shown in FIG. 16, the holding means 32 includes a shaft member 33, a spring 34, and a shaft member 35, and is rotatable about the shaft member 33. A spring receiver 33 a is formed at the base end of the shaft member 33, and a spring 34 is interposed between the spring receiver 33 a and the dialysate extraction means 9. As a result, the holding means 32 is constantly urged in the left direction in the figure by the urging force of the spring 34.

  The cap 10 ′ is supported at the tip of the shaft member 35 and is rotatable about the shaft member 35. That is, the cap 10 ′ is rotatable about the shaft member 33 and is rotatable about the shaft member 35. The cap 10 'is attached with a sealing means 11 similar to that of the first embodiment for sealing with the outer peripheral surface of the sampling port 9c, while the female screw portion as in the first embodiment is attached. (Screw portion screwed into the male screw portion 9ca of the sampling port 9c) is not formed.

  Thus, in a state where the cap 10 ′ covers the sampling port 9c (see FIG. 16), the cap 10 ′ is pressed against the sampling port 9c by the urging force of the spring 34 so that the closed state is maintained. . Further, when the holding means 32 is moved together with the cap 10 ′ against the urging force of the spring 34 (moving in the right direction in the figure), the cap 10 ′ is separated from the sampling port 9c as shown in FIG. If the cap 10 ′ is further rotated about the shaft member 33 as shown in FIG. 18, the sampling port 9c can be opened as shown in FIG. Thereby, connection means, such as the syringe S and a connection line, can be connected to the collection port 9c. When the cap 10 'is rotated around the shaft member 35 from the state shown in FIG. 17, the direction of the cap 10' is reversed as shown in FIG. If it is in this state, replacement | exchange, maintenance, etc. of the sealing means 11 can be performed easily.

  According to the present embodiment, the cap 10 'can be securely and reliably sealed with respect to the sampling port 9c, and when the sampling port 9c is opened, loss of the cap 10' can be avoided. . Further, if a detection means for detecting the direction of the holding means 32 (the rotational position around the shaft member 33) is provided, it can be detected whether the sampling port 9c is in an open state or a closed state. . In addition, although the dialysate extraction means which concerns on this embodiment is the same as that of 1st Embodiment, it is good also as a thing like another form.

Next, a dialysate extraction device according to a third embodiment of the present invention will be described.
As in the first embodiment, the dialysate extraction apparatus according to this embodiment is connected to the dialysate introduction line L1 of the blood purification apparatus as shown in FIG. 1, and as shown in FIGS. An introduction port 36a and a discharge port 36b that are connected to the liquid introduction line L1 (liquid flow path) and can flow the liquid (dialysis solution) are formed, and a collection port 39 that can collect the flowed liquid is provided. The formed dialysate extraction means 36 and a cap 37 as an opening / closing means that can be attached to and detached from the collection port 39 of the dialysate extraction means 36 and can open and close the collection port 39 are provided.

  More specifically, the dialysate extraction means 36 has a dialysate introduction line L1 connected to each of the inlet 36a and outlet 36b so that the dialysate can be circulated therein. The flow path through which the dialysate flows from the inlet port 36a toward the outlet port 36b is bent approximately 90 degrees at the branch portion P and extends in an L shape, and the sampling port 39 is connected to the inlet port 36a. It is formed so as to be located on substantially the same straight line.

  Furthermore, the dialysate extraction means 36 has a cylindrical outer peripheral wall 40 that covers the outer periphery of the collection port 39. The outer peripheral wall portion 40 is formed with a screw portion 40a that can be screwed with the screw portion 37a of the cap 37 (opening / closing means) on the outer peripheral surface thereof, and the screw portion 42ba ( Screw portions 40b that can be screwed together are formed respectively (see FIGS. 23 and 24). That is, the sampling port 39 can be connected to the connection line L3 via the connection means 42 by locking and fixing the connection means 42 to the outer peripheral wall portion 40.

  Furthermore, the outer peripheral wall portion 40 according to the present embodiment is configured to protrude so as to cover the protruding end 39 a of the sampling port 39. That is, the projecting dimension of the outer peripheral wall 40 is set to be larger than the projecting dimension of the sampling port 39, so that the projecting end 39 a of the sampling port 39 is covered with the outer peripheral wall 40. Thereby, even when the cap 37 is removed from the collection port 39, it is possible to prevent a human finger from touching the collection port 39, and hygiene management can be more reliably achieved.

  As shown in FIG. 23, the connecting means 42 is attached to the distal end portion of the connection line L3 for circulating the liquid collected from the collection port 39, and has a substantially cylindrical member having an inner peripheral surface 42a and an outer peripheral surface 42b. It consists of A screw portion 42ba that can be screwed with the screw portion 40b of the outer peripheral wall portion 40 is integrally formed on the distal end side (the connection site side with the sampling port 39) of the outer peripheral surface 42b. Thus, as shown in FIG. 24, the inner peripheral surface 42a of the connecting means 42 is fitted to the outer peripheral surface of the sampling port 39, and the screw portion 42ba of the outer peripheral surface 42b of the connecting means 42 is the inner periphery of the outer peripheral wall portion 40. The connection line L3 can be connected to the sampling port 39 by being locked by screwing with a screw portion 40b formed on the surface.

  The connection line L3 according to the present embodiment is connected to, for example, an air trap chamber 5 connected to the arterial blood circuit 2 or an air trap chamber 6 connected to the venous blood circuit 3, and is connected to the dialysate introduction line L1. The dialysate can be supplied to the arterial blood circuit 2 or the venous blood circuit 3. Thereby, priming, replacement fluid, blood return, or the like can be performed using the dialysis solution, or the dialysis solution can be used as a replacement solution for the treatment of online HDF or online HF.

  As described above, the outer peripheral surface 42 b of the connection means 42 is locked to the inner peripheral surface of the outer peripheral wall 40 while the inner peripheral surface 42 a of the connection means 42 is fitted to the outer peripheral surface of the sampling port 39. Since the connection line L3 is connectable, the connection surface of the connection means 42 to the sampling port 39 is the inner peripheral surface (inside of the connection means 42), so that a human finger touches the connection surface. Can be avoided, and hygiene management can be more reliably achieved.

  The cap 37 as an opening / closing means can be attached to the outer peripheral wall portion 40 by screwing the screw portion 37a formed on the inner peripheral surface thereof with the screw portion 40a of the outer peripheral wall portion 40. . As shown in FIG. 21, the cap 37 according to the present embodiment includes a sealing unit 38 that seals between the protruding end surface 40 c of the outer peripheral wall portion 40. The sealing means 38 is attached to one surface of the attachment member D, and is always urged together with the attachment member D by the spring S1 toward the protruding end surface 40c side (the sampling port 39 side) of the outer peripheral wall portion 40. The seal can be designed.

  Here, the collection port 39 of the dialysate extraction means 36 according to the present embodiment has a guide path α for guiding the liquid introduced from the introduction port 36a into the collection port 39 with the cap 37 attached thereto, A discharge path β for discharging the liquid guided by the guide path α to the outlet port 36b is defined. That is, when the cap 37 is screwed and attached to the outer peripheral wall portion 40, the projecting end surface 40c of the outer peripheral wall portion 40 is sealed by the sealing means 38 to form a sealed space. At 39, a guide path α and a discharge path β are defined. Thus, the inside of the sampling port 39 is used as the guide path α, and the space between the outer peripheral surface of the sampling port 39 and the inner peripheral surface of the outer peripheral wall portion 40 is used as the discharge path β.

  As described above, the sampling port 39 according to the present embodiment has a function of collecting the liquid by connecting the connecting means 42 and the like, and in the state where the cap 37 is attached, the guide path α and the discharge path β are provided. It has a function to define. In the present embodiment, the sampling port 39 is formed of a cylindrical member. However, any other shape (for example, a rectangular cross section) may be used as long as it is a cylindrical member that can define the guide path α and the discharge path β. It may be of a shape or the like.

  On the other hand, the dialysate extraction means 36 is formed with a connection path γ for connecting the discharge path β and the flow path on the branching portion P side. As a result, the liquid flowing from the inlet 36a toward the tip of the sampling port 39 via the branch portion P and the guide path α is discharged from the outlet 36b through the discharge path β and the connecting path γ, and from the inlet 36a. The liquid that flows toward the outlet port 36b via the branch portion P can join and flow out of the outlet port 36b.

  Further, the dialysate extraction means 36 according to the present embodiment makes the pressure of the liquid flowing toward the guide path α out of the liquid introduced from the inlet 36a larger than the pressure of the liquid flowing toward the outlet 36b. Difference forming means 41 is provided. The pressure difference forming means 41 is disposed in the vicinity of the branch portion P of the dialysate extraction means 36, has a liquid flow passage 41a that flows from the introduction port 36a toward the collection port 39, and the flow passage 41a. Is a tapered surface in which the diameter of the flow path gradually decreases toward the sampling port 39 side (right side in FIG. 20). As a result, the pressure of the liquid flowing from the inlet 36a toward the collection port 39 can be relatively increased with respect to the pressure of the liquid flowing from the inlet 36a toward the outlet 36b.

  Further, the pressure difference forming means 41 and the sampling port 39 according to the present embodiment are made of an integral part (for example, an integrally molded part). As described above, if the pressure difference forming means 41 and the sampling port 39 are made of an integral part, the number of parts in the dialysate extraction means 36 can be reduced, and the manufacturing cost and the maintenance cost can be reduced. . The pressure difference forming means 41 and the sampling port 39 may be formed separately and connected to form an integrated part.

  Furthermore, a sealed portion 41b is formed at a portion of the pressure difference forming means 41 that faces the seal member 36c, and the pressure difference forming means 41 and the sampling port 39 are separated from the seal member 36c by the spring S2. The sealed portion 41b is always urged in the direction of separating. Then, when the connection means 42 is connected to the sampling port 39 (that is, in the process in which the screw portion 42ba of the outer peripheral surface 42b of the connection means 42 is screwed with the screw portion 40b formed on the inner peripheral surface of the outer peripheral wall portion 40. ), The pressure difference forming means 41 and the sampling port 39 move against the urging force of the spring S2, and the sealed portion 41b contacts and seals against the sealing member 36c, so that the connecting path γ can be blocked. It is like that.

  Thus, in a state where the connection means 42 is connected to the sampling port 39, the liquid is blocked from flowing to the outside via the discharge path β. Thus, in the state where the connection means 42 is connected to the collection port 39, the liquid is blocked from flowing to the outside via the discharge path β. Therefore, when collecting the liquid from the collection port 39 via the connection means 42, The liquid can be reliably prevented from leaking to the outside from the discharge path β, and the collected liquid can be circulated better to the connection line L3.

According to the third embodiment, the collection port 39 guides the liquid introduced from the introduction port 36a to the protruding end 39a side of the collection port 39 with the cap 37 (opening / closing means) attached. And a discharge path β for discharging the liquid guided by the guide path α to the outlet 36b side, it is possible to distribute cleaning water or disinfecting liquid through the guide path α and the discharge path β. The inside of the sampling port 39 can be reliably cleaned and disinfected without extending a separate flow path from the cap 37. Furthermore, since the collection port 39 has the function of defining the guide path α and the discharge path β in addition to the function of collecting the liquid, the configuration can be simplified by eliminating the need for separate defining means.

  The dialysate extraction means 36 has a cylindrical outer peripheral wall portion 40 that covers the outer periphery of the sampling port 39, and the cap 37 has a sealing means 38 that seals between the protruding end surface 40 c of the outer peripheral wall portion 40. Since the cap 37 is attached to the sampling port 39, the guide channel α and the discharge channel β can be more reliably defined and the cleaning water or the disinfectant can be distributed more favorably. Can be made.

  Further, the inside of the sampling port 39 is set as the guide path α, and the gap between the outer peripheral surface of the sampling port 39 and the inner peripheral surface of the outer peripheral wall portion 40 is set as the discharge path β. Wash water or disinfectant can be distributed more smoothly and satisfactorily through β. Furthermore, the dialysate extraction means 36 is a pressure difference forming means 41 for making the pressure of the liquid flowing toward the guide path α out of the liquid introduced from the introduction port 36a larger than the pressure of the liquid flowing toward the outlet port 36b. Therefore, the cleaning water or the disinfecting liquid can be more reliably circulated through the guide path α and the discharge path β by the pressure difference generated by the pressure difference forming means 41.

  The pressure difference forming means 41 includes a liquid flow passage 41a that flows from the introduction port 36a toward the collection port 39, and the flow passage 41a has a flow path diameter toward the collection port 39 side. Since the tapered surface is gradually reduced, the pressure of the liquid flowing from the inlet port 36a toward the guide path α can be made relatively larger than the pressure of the liquid flowing from the inlet port 36a toward the outlet port 36b. Thus, it is possible to reliably distribute the cleaning water or the disinfecting liquid to the guide path α and the discharge path β.

  In addition, according to the present embodiment, the introduction port 36a and the collection port 39 are formed on substantially the same straight line, so that the liquid introduced from the introduction port 36a flows toward the collection port 39 as it is, The cleaning water or the disinfecting liquid can be circulated through the guide path α and the discharge path β more reliably and satisfactorily, and the cleaning and disinfection inside the sampling port 39 can be more reliably performed.

According to the first to third embodiments and the first to fifth reference examples of the present invention, the cleaning water or the disinfecting liquid can be circulated through the guide path and the discharge path, and the separate flow path from the opening / closing means. Thus, it is possible to provide a blood purification apparatus (hemodialysis apparatus) capable of reliably cleaning and disinfecting the inside of the sampling port without extending the length of the apparatus. In particular, according to the first and second embodiments and the first to fifth reference examples , the cap 10 (opening / closing means) is provided with the defining means 12, and the guide means α and the discharge path are formed by the defining means 12. Wash water or disinfectant can be circulated through β, so that the inside of the sampling port 12 can be reliably cleaned and disinfected. On the other hand, according to the third embodiment, the sampling port 39 defines the guide path α and the discharge path β in a state where the cap 37 (opening / closing means) is attached. The cleaning water or the disinfecting liquid can be circulated through the guide path α and the discharge path β without providing the above, so that the inside of the sampling port 39 can be reliably cleaned and disinfected.

Having described the present embodiment, the present invention is not limited thereto, may be one having no check valve or closure means, for example. The defining means 12 defines the inside of the sampling port in a state attached to the sampling port, guides the liquid introduced from the inlet into the sampling port, and guides the guide through the guide channel α. Any other shape may be used as long as it forms a discharge path β for discharging the liquid to the outlet side.

  Furthermore, the blood purification apparatus to which the present embodiment is applied may be of any form, for example, a device that introduces or discharges dialysate in a chamber instead of the dual pump 7, or a dialyzer 1. It is good also as what equipped the blood purifier of another form. Furthermore, in the present embodiment, each is disposed in the dialysate introduction line L1 of the dialyzer body, but may be disposed in another flow path in the dialyzer body.

With the opening / closing means attached to the sampling port, a guide path for guiding the liquid introduced from the inlet into the sampling port and a discharge path for discharging the liquid guided by the guide path to the outlet port side are formed. with that, dialysate extraction means, among the liquid introduced from the inlet, provided with a pressure difference forming means for increasing the pressure of the liquid flowing through the pressure of the liquid flowing towards the guide path toward the outlet, and The pressure difference forming means has a flow passage for the liquid flowing from the introduction port toward the collection port, and the flow passage has a tapered surface in which the diameter of the flow path gradually decreases toward the collection port side. As long as the dialysate extraction device is used, the present invention can be applied to devices having different external shapes or those having other functions.

1 ... Dializer (blood purifier)
DESCRIPTION OF SYMBOLS 2 ... Arterial side blood circuit 3 ... Vein side blood circuit 4 ... Blood pump 5 ... Arterial side air trap chamber 6 ... Vein side air trap chamber 6a ... Overflow line 7 ... Duplex pump 8 ... Dewatering pump 9 ... Dialysate extraction means 10 ... Cap (opening / closing means)
DESCRIPTION OF SYMBOLS 11 ... Sealing means 12 ... Definition means 13 ... Pressure difference formation means 14 ... Dialysate extraction means 15 ... Guide member 16 ... Dialysate extraction means 17 ... Guide member 18 ... Dialysate extraction means 19 ... Interlocking member 20 ... Spring 21 ... Dialysate extraction means 22 ... sliding member 23 ... spring 24 ... seal member 25 ... dialysate extraction means 26 ... sliding member 27 ... interlocking member 28 ... seal member 29 ... spring 30 ... spring 31 ... seal member 32 ... holding means 33 ... Shaft member 34 ... Spring 35 ... Shaft member 36 ... Dialysate removal means 37 ... Cap (opening / closing means)
38 ... Sealing means 39 ... Sampling port 40 ... Outer peripheral wall 41 ... Pressure difference forming means 42 ... Connecting means G ... Check valve

Claims (10)

A dialysis fluid extraction means in which an inlet and an outlet through which the liquid can be circulated by being connected to the liquid flow path are formed, and a sampling port from which the circulated liquid can be collected is formed;
An opening / closing means capable of being attached to and detached from the collection port of the dialysate extraction unit and capable of opening and closing the collection port;
In the dialysate extraction device comprising
With the opening / closing means attached to the sampling port, a guide path for guiding the liquid introduced from the introduction port into the sampling port, and a discharge for discharging the liquid guided by the guide path to the outlet port side And the dialysate extraction means makes the pressure of the liquid flowing toward the guide path out of the liquid introduced from the inlet larger than the pressure of the liquid flowing toward the outlet. A pressure difference forming means, and the pressure difference forming means has a flow passage for liquid flowing from the introduction port toward the collection port, and the flow passage has a diameter of the flow channel. A dialysate extraction device, characterized by a tapered surface that gradually decreases toward the mouth side. The opening / closing means includes
Sealing means for sealing between the outer peripheral surface of the sampling port;
A defining means for defining the inside of the sampling port in a state attached to the sampling port, and forming the guide path and the discharge path;
The dialysate extraction device according to claim 1, comprising:   The defining means comprises a cylindrical member extending in the sampling port with the opening / closing means attached to the sampling port, and the inside of the cylindrical member serves as the guide path, and the cylindrical shape The dialysate extraction device according to claim 2, wherein the discharge path is between the outer peripheral surface of the member and the inner peripheral surface of the sampling port.   The tubular member is formed with a communication part for communicating the guide path and the discharge path, and the communication part generates a vortex or a turbulent flow with respect to the liquid flowing from the guide path to the discharge path. The dialysate extraction device according to claim 3, wherein the dialysate extraction device can be used.   The dialysate extraction device according to claim 1, wherein the sampling port defines the guide path and the discharge path in a state where the opening / closing means is attached.   The dialysate extraction means has a cylindrical outer peripheral wall portion covering the outer periphery of the sampling port, and the opening / closing means includes a sealing means for sealing between the outer peripheral surface or the protruding end surface of the outer peripheral wall portion. The dialysate extraction device according to claim 5. 7. The dialysis according to claim 6, wherein the inside of the sampling port is the guide path, and the discharge path is between the outer peripheral surface of the sampling port and the inner peripheral surface of the outer peripheral wall portion. Liquid take-out device.   The dialysate extraction means includes a check valve that allows the liquid to flow out of the sampling port and blocks the flow of liquid from the sampling port. The dialysate extraction device described in 1.   The dialysate extraction means allows the flow of liquid in the guide path and the discharge path when the opening / closing means is attached to the collection port, and when the collection port is open, The dialysis fluid extraction device according to any one of claims 1 to 7, further comprising a closing means for closing.   A blood purification apparatus comprising the dialysate extraction apparatus according to any one of claims 1 to 9.

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