JP5957256B2 - Energy-saving air conditioning control system in a clean room - Google Patents

Description

  The present invention relates to an energy saving air conditioning control system in a pharmaceutical clean room.

  In a clean room of a pharmaceutical manufacturing plant as shown in FIG. 6, the air conditioner is operated according to the maximum number of ventilations determined from the removal of sensible heat in the room regardless of the operation status of indoor production equipment and the presence or absence of people. Is generally operated continuously at a constant air flow rate.

  If it is not particularly necessary to operate the air conditioner continuously at a constant air flow without considering the operation status of indoor production equipment in the clean room or the presence of people, it will be a waste of energy. There may be.

  Therefore, an air volume control system for a clean room comprising a plurality of production apparatuses and a plurality of air purifiers that change the air cleanliness in accordance with the operating status of indoor production equipment. An air volume control system for a clean room has been proposed (see Patent Document 1), characterized in that it includes air purifier control means for controlling the air volume for each air purifier based on operation information.

  On the other hand, the number of operation of the substrate processing apparatus in the clean room and the number of workers entering the clean room are acquired by the air conditioning controller that controls the air conditioner, and both the acquired operation number and number of rooms are 0. In some cases, the temperature and humidity adjustment range is set to a power saving range that is less stringent than the normal range, and the number of times air is circulated in the clean room is set to the minimum required number of times that is less than the normal number. An air conditioning method for a clean room has been proposed that can reduce the running cost and save energy by eliminating the need to operate the air conditioning device at the maximum capacity when there is little need for state adjustment (see Patent Document 2). .

  However, this air conditioning method has a complicated entrance management system and is suitable for a clean room for a substrate processing apparatus. However, it is not in operation but should be used when a drug is present in the clean room. It does not necessarily fit.

JP 2005-098661 A JP 2004-190972 A

  The present invention was created to solve the various problems described above. When a person is present in a clean room or when a medicine is present in the clean room, the air purification treatment is applied to a certain amount. The purpose is to provide a clean room for the production of high-quality pharmaceutical drugs with thorough energy conservation by implementing extremely strict air purification and temperature control while the equipment is in operation.

The present invention is an air conditioning system for a clean room for pharmaceutical manufacture , comprising an air conditioner, a temperature / humidity sensor for detecting temperature / humidity, a human detection sensor for detecting the number of people in the room, the air conditioner, the temperature / humidity sensor, In an energy-saving air conditioning system configured with a control device connected to a human detection sensor , a human detection sensor is provided for each divided detection target area of a clean room, and the control device includes the human detection sensor as a human presence sensor. Is not detected, and the medicine distribution signal is not received, the number of ventilation times of the clean room indoor air is controlled to the minimum necessary number in the absence, and when the human detection sensor detects the presence of a person, or When a distribution signal is received, the ventilation frequency of the clean room room air is controlled to the minimum required number of times when present, and air conditioning is performed to an appropriate cleanliness.

Furthermore, the present invention is an energy saving air conditioning system, wherein the human detection sensor is
An infrared detector comprising a multi-surface reflecting mirror or a multi-surface lens and a thermopile array consisting of three or more elements, a correction temperature sensor for measuring the surface temperature of the dust-proof cover and housing or the air temperature around the sensor installation location; Information on the signal processing unit that processes the analog signals, the arithmetic processing unit (CPU) that takes in the processed signal and determines the human body detection signal and the heat source determination signal information by the data analysis by the human body detection algorithm, and information on the external device And an input / output unit for transmitting and receiving
It is characterized by detecting an approach state, a leaving state, or a stationary stay state and discriminating a heat source other than a person.
In the invention according to claim 2 , the energy saving air conditioning system further includes a production equipment operation status determination device, and the control device derives the optimum ventilation frequency based on the production equipment operation information from the production equipment operation status judgment device, It is characterized by controlling the number of ventilations in the clean room to the optimum number of ventilations and air-conditioning to an appropriate cleanliness.

The invention according to claim 3 is characterized in that the control device includes air flow rate changing means for forcibly increasing / decreasing the set air flow rate when the temperature setting upper limit value or the lower limit value is exceeded. Yes.

In the invention according to claim 4 , the production equipment operation status determination device is at least one of a power supply status such as a current value, a heat generation amount due to a thermopile of the production equipment, information from a production management system, number of people information from a human detection sensor, etc. One of them is transmitted to the control device.

Furthermore, the present invention can maintain the current cleanliness for a predetermined time when the human detection sensor shifts from a human presence detection state to a non-detection state .

  According to the first aspect of the present invention, when the human detection sensor does not detect the presence of the person and the preparation detection sensor does not detect the presence of the preparation, the control device sets the ventilation frequency of the clean room indoor air to 6 times / Control to the minimum required number of absences in the absence of about h, and when either human detection sensor or drug product detection sensor detects the presence, control the number of ventilation times of clean room indoor air to the minimum required number of times in the presence of about 10 times / h Thus, energy saving can be realized while air-conditioning to an appropriate cleanliness.

  According to the invention of claim 2, since the energy saving air conditioning system further includes the production equipment operation status determination device, the control device performs the optimum ventilation frequency based on the production equipment operation information from the production equipment operation status judgment device. Thus, it is possible to control the number of ventilations in the clean room to the optimum number of ventilations to air-condition the air to an appropriate cleanliness level, while contributing to energy saving.

  According to the invention of claim 3, since the control device includes the air flow rate changing means for forcibly increasing or decreasing the set air flow rate when the temperature setting upper limit value or the lower limit value is exceeded, It is possible to flexibly cope with avoiding rigid driving.

  According to the invention of claim 4, the production equipment operating status determination device includes a power supply status such as a current value, a heat generation amount due to a thermopile of the production equipment, information from the production management system, and information on the number of people from the human detection sensor Since at least one of them can be transmitted to the control device, a flexible system construction is possible.

  According to the fifth aspect of the present invention, when the human detection sensor shifts from the human presence detection state to the non-detection state, the current cleanliness is maintained for a predetermined time. A decrease can be prevented.

1 is a schematic configuration diagram of an energy saving air conditioning system of the present invention. It is a flowchart of the control apparatus of this invention. It is a drawing substitute photograph showing a human detection sensor of the present invention. It is a functional block diagram of the human detection sensor of this invention. It is a detection area general view which shows dividing the whole object area of the human detection sensor of the present invention into six unit detection object areas. 1 is a schematic diagram of a conventional air conditioning system.

<< System configuration >>
This clean room energy-saving air conditioning system has a basic configuration of an air conditioner, a human detection sensor installed for every 1.8 m 2 for calculating the number of people in the room, and a control device installed in the ceiling.

The external air introduction pipe OA and the indoor air circulation path RA are supplied to the clean room by the supply pipe SA via the HEPA filter.
This energy-saving air conditioning system is characterized by including a human detection sensor that calculates the number of people in the room.
Further, as shown in FIG. 1, an outside air processing unit, the indoor unit, the human detection sensor, and a control device (not shown) connected to an indoor temperature / humidity sensor that detects indoor temperature / humidity are provided.

≪High-precision human detection sensor≫
The details of this high-precision human detection sensor are described in Japanese Patent Application Laid-Open No. 2010-256045. As shown in FIG. 3, the outline of the high-precision human detection sensor is a multi-surface reflection mirror or multi-surface lens composed of two or more surfaces and three elements. Infrared detector composed of the thermopile array consisting of the above, a dustproof cover, a surface temperature of the housing, or a correction temperature sensor for measuring the air temperature around the sensor installation location, and signal processing for processing these analog signals And an arithmetic processing unit (CPU) for determining information such as a human body detection signal and a heat source determination signal (OA device determination signal) by data analysis using a human body detection algorithm for an office and an external device An input / output unit that transmits and receives information.

Referring to FIGS. 4 and 5, the infrared detection unit of the present embodiment is composed of six-element thermopile array circle numbers 1 to 6 and six-surface reflecting mirrors A to F.
The surfaces A to F of the six-surface reflecting mirror correspond to the six unit detection target areas in the zones A to F shown in FIG. 5, and each of the six elements is included in each surface A to F of the reflecting mirror. On the other hand, it has a mirror surface that collects infrared rays.
That is, the detection target area of the present embodiment is divided into six unit detection target areas in zones A to F. Thereby, the detection target area of the human body detection sensor is widened and the detection accuracy is enhanced.
Therefore, although detection signals are input from the six unit detection target areas A to F to each element, the sum of the detection signals from the six unit detection target areas is used as a detection signal for each element thermopile array.
Note that the output level of the detection signal decreases as the temperature increases and the amount of infrared rays increases.
In the present embodiment, the light collector is configured by a six-surface reflecting mirror, but may be configured by a lens that focuses light on six elements.

As shown in FIG. 5, the elements corresponding to the unit detection target areas A to F are composed of two sets of six elements of circle numbers 1 to 3 and circle numbers 4 to 6, and each set of elements. Is composed of the central main element round numbers 2, 5 and the subelement round numbers 1, 3, 4 and 6 on both sides.
In this way, one set of three elements, with the center as the main element and both sides as the sub elements, the element located at the center has high sensitivity, and as can be understood from FIG. This is because the temperature information signal of other areas other than the monitoring area is hardly received.
Therefore, the present invention requires at least three elements.
And when adding this, since 3 elements are performed as 1 set, the element of the multiple of 3 will be provided.
In this embodiment, this means that two sets of elements are provided.
Note that the number of elements in each set need not be an odd number, and can be an even number. In this case, the average of the detection values of the two elements on the center side may be used as the detection value of the main element.

The signal processing unit filters the signal detected by each element of the thermopile array with a hardware filter, receives the signal from the temperature sensor for correction shown in FIG. 4, corrects the detected value of each element, and outputs the output level. It is intended to adjust.
The processing for receiving the signal from the correction temperature sensor and correcting the detection value of each element can also be executed in the arithmetic processing unit.
Therefore, in the following, it is described that correction processing is performed in the arithmetic processing unit.

And the detection signal from a sensor and the signal from the temperature sensor for correction | amendment are input into the said arithmetic processing part (CPU), and the parameter calculated in an arithmetic processing part is as follows.
・ Fluctuation amount per unit time of detection value of each element, that is, slope of detection value ・ Increase / decrease (increase / decrease) in detection value of each element
-Amount of change in the detected value of each element-An element in which the detected value changes (classification of main element or sub-element)
-The number of elements in which the detected value changes-Difference in detection value change start time between each element-Difference in detected value change between each element-Difference in detected value between elements (for example, element 1 and Difference between elements of element 3)

In addition, what is calculated by the CPU and stored in a storage unit (not shown) and used to determine the current state of each detection area is as follows.
・ Absence base value ・ Detected value before human body movement ・ Correction judgment value ・ Human body detected value
・ Estimated number of people (approximate number or one / multiple detection)
-Residual heat judgment value (used to exclude the effects of residual heat remaining after the human body leaves)

≪High-precision human detection sensor function≫
The high-precision human detection sensor according to the present invention can detect not only the approaching state and the leaving state but also the stationary staying state.
As a result, it can be determined that the person is staying even if the person does not move at all for a long time in the detection area and remains completely stationary.
And this high-precision human detection sensor is affected by temperature change in a short time (several minutes to several tens of minutes) due to air conditioning control, etc., and temperature change in the external environment and the entire area for a long time (1 to several hours). Remove the effects of solar radiation in the perimeter zone.
For this reason, it is possible to distinguish between the human body and other heat sources such as a drug manufacturing apparatus, and the human body and the remaining heat of the human body remaining on a chair, desk, floor, etc. Although not shown, the absence / stay / entrance of the human body / Determination status and human body motion detection status, can detect a stationary human body over a long period of time and detect a completely stationary human body, know whether one or more people stay in the detection area, The human body can be detected in a non-steady state when the temperature is lower than the floor surface temperature.

The control procedure of the embodiment of the present invention will be described based on the flowchart of FIG.
This flowchart shows a routine executed for each unit section set as an air conditioning zone.

  The control device stores the set temperature set by the room temperature setter (not shown) for each air-conditioning zone, and determines whether or not the preparation exists in the manufacturing chamber (step 1). Whether or not a preparation exists in the manufacturing chamber is determined based on, for example, a distribution signal from the production management system.

When it is determined that the preparation is present in the manufacturing chamber, it is further determined whether or not the production equipment is operating (step 2).
Whether a production device is in operation depends on whether the production device operation status judgment device is in the power supply status such as the current value, the amount of heat generated by the thermopile of the production device, information from the production management system, or the number of people from the human detection sensor. By transmitting at least one of information and the like to the control device, it is determined whether the control device is in operation.

  When the control device determines in step 2 that the production equipment is in operation, it obtains production equipment operation information, that is, a part of the information described in the previous paragraph 0033 (step 3).

  Based on the operation information of the production equipment acquired in step 3, the optimum ventilation frequency is calculated and derived (step 4). The control device controls the air flow rate of the SA so that the ventilation frequency of the clean room becomes the derived optimal ventilation frequency.

  The control device repeats the control in an infinite loop until the optimum ventilation frequency reaches a set time, for example, about 10 minutes (step 7), returns to step 3 and acquires the operation information of the production equipment again, and the above infinite Repeat the loop.

  When the set time has elapsed in step 7, the process returns to step 1 to determine whether or not there is a preparation in the clean room. If a formulation is present, the above control is continued.

  Returning to Step 1 and conversely, when it is determined that there is no preparation in the clean room, the air volume in the clean room is made the least a time by making the SA air volume constant in Step 8, and 6 times in this embodiment. Set to / h.

Here, information is acquired from the human detection sensor which is a feature of the present invention.
As a result, when it is found that there is a person in the clean room, the cleanliness may be deteriorated by dust generation by the person, so the number of times of ventilation of the air in the clean room set earlier is b times / h, this In the embodiment, the speed is increased to 10 times / h.
Of course, if the person is absent, the ventilation frequency is not changed.

  In addition, when the control device changes from the state where the person was present in the clean room to the absence state in step 10, the current cleanliness is set for a predetermined time in order to prevent dust from scattering and adhering to the preparation. It is extremely effective to maintain.

On the other hand, regardless of whether or not a person is present in the clean room, in steps 1 and 2 described above, the number of times of air ventilation in the clean room even when the preparation is present in the clean room but the production equipment is not operating. Is increased to b times / h, and in this embodiment, 10 times / h.
This is to ensure the cleanliness in the clean room when the preparation is present, as well as the influence of dust scattering and adhesion from humans.

As in the above embodiment, full automation is an effective measure in a sense, but it is possible to manually increase the air volume after the signal from the production equipment operation status judgment device changes to a non-operation signal. A manual button may be provided.
Furthermore, setting by remote control by an automatic control panel, a central monitoring panel, or the like may be possible.

Moreover, you may provide the monitor function which can visually check the frequency | count of ventilation or the ventilation air volume currently controlled.
This monitoring function can further contribute to energy saving if it is automatically released while the production equipment is not in operation.

  Furthermore, it is also effective that the control device includes an air flow rate changing means for forcibly increasing / decreasing the set air flow rate when the temperature setting upper limit value or the lower limit value is exceeded. As this incidental function, a pre-alarm function can be provided by providing a set value before the upper limit value and the lower limit value.

It is also possible to have a function of changing the indoor set temperature, relative humidity, etc., depending on the operating status of human detection sensors, production equipment, and the like.
In addition, an automatic release function for automatically canceling environmental monitoring for recording temperature and humidity can be provided at the time of non-manufacturing. In such a case, it is effective to have a function of automatically switching the set air temperature, the dew point temperature, the air flow rate, etc. to the set values.

  It is also possible to provide a monitor device that displays various energy saving effects, energy usage, etc. by the control according to the present invention, and further, it operates in the production equipment and the automatic transfer equipment of the production equipment according to the control state of the present invention. It is also possible to add a function capable of issuing a signal for controlling the above.

  The program according to the present invention is preferably capable of supporting computerized system validation (CSV) required for a pharmaceutical manufacturing facility.

Claims (4)

An air conditioning system for a clean room for pharmaceutical manufacturing,
An air conditioner,
A temperature and humidity sensor that detects temperature and humidity;
A human detection sensor that detects the number of people in the room;
A control device connected to the air conditioner, the temperature / humidity sensor, and the human detection sensor;
In the energy-saving air conditioning system composed of
The human detection sensor
It is provided for each detection target area divided into clean rooms.
An infrared detector comprising a multi-surface reflecting mirror or a multi-surface lens and a thermopile array comprising three or more elements;
A temperature sensor for correction that measures the surface temperature of the dust-proof cover and housing or the air temperature around the sensor installation location;
A signal processing unit for processing those analog signals;
An arithmetic processing unit (CPU) that takes in the processed signal and determines the human body detection signal and the heat source determination signal information by data analysis using a human body detection algorithm;
An input / output unit for transmitting / receiving information to / from an external device;
Consisting of
Detecting entry and exit states or stationary stays,
It distinguishes between heat sources other than people,
The control device includes:
When the human detection sensor does not detect the presence of a person and does not receive a medicine distribution signal, the ventilation frequency of the clean room indoor air is controlled to the minimum required number in the absence,
When the human detection sensor detects the presence of a person or receives a medicine distribution signal, the ventilation frequency of the clean room room air is controlled to the minimum required number of times in the presence, and air conditioning is performed to an appropriate cleanliness. An energy-saving air conditioning system. The energy-saving air-conditioning system further includes production equipment operation status judgment equipment,
The control device derives the optimum ventilation frequency based on the production equipment operation information from the production equipment operation status judgment device, controls the ventilation frequency of the clean room to the optimum ventilation frequency, and air-conditions to an appropriate cleanliness level. The energy-saving air-conditioning system according to claim 1 . The control device, when exceeding the temperature set upper limit value or the lower limit value, to claim 1 or 2, characterized in that it comprises a blowing amount changing means for forcibly increasing or decreasing change the air blowing amount set The energy-saving air conditioning system described. The production device operating status determination device controls at least one of a power supply status such as a current value, a heat generation amount of the production device by a thermopile, information from a production management system, number of people information from the human detection sensor, and the like. It transmits to an apparatus, The energy saving air-conditioning system described in any one of Claims 1-3 characterized by the above-mentioned.