JP5883330B2 - コリメートされたガス流及び粒子源を用いる送達機器及び方法 - Google Patents

コリメートされたガス流及び粒子源を用いる送達機器及び方法 Download PDF

Info

Publication number
JP5883330B2
JP5883330B2 JP2012077750A JP2012077750A JP5883330B2 JP 5883330 B2 JP5883330 B2 JP 5883330B2 JP 2012077750 A JP2012077750 A JP 2012077750A JP 2012077750 A JP2012077750 A JP 2012077750A JP 5883330 B2 JP5883330 B2 JP 5883330B2
Authority
JP
Japan
Prior art keywords
tissue
particles
drug
gas
collimator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012077750A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012223562A (ja
JP2012223562A5 (https=
Inventor
スコット・ユーランド
エリック・ピーターズ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palo Alto Research Center Inc
Original Assignee
Palo Alto Research Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palo Alto Research Center Inc filed Critical Palo Alto Research Center Inc
Publication of JP2012223562A publication Critical patent/JP2012223562A/ja
Publication of JP2012223562A5 publication Critical patent/JP2012223562A5/ja
Application granted granted Critical
Publication of JP5883330B2 publication Critical patent/JP5883330B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
JP2012077750A 2011-04-19 2012-03-29 コリメートされたガス流及び粒子源を用いる送達機器及び方法 Active JP5883330B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/089,769 2011-04-19
US13/089,769 US8388569B2 (en) 2011-04-19 2011-04-19 Delivery devices and methods with collimated gas stream and particle source

Publications (3)

Publication Number Publication Date
JP2012223562A JP2012223562A (ja) 2012-11-15
JP2012223562A5 JP2012223562A5 (https=) 2015-05-21
JP5883330B2 true JP5883330B2 (ja) 2016-03-15

Family

ID=46045799

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012077750A Active JP5883330B2 (ja) 2011-04-19 2012-03-29 コリメートされたガス流及び粒子源を用いる送達機器及び方法

Country Status (3)

Country Link
US (1) US8388569B2 (https=)
EP (1) EP2514477B1 (https=)
JP (1) JP5883330B2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH705153A1 (fr) * 2011-06-24 2012-12-31 Heidi Hall Mors et système pour envoyer une substance visqueuse et/ou liquide dans la bouche d'un animal.
EP2764884A1 (en) * 2013-02-11 2014-08-13 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Method and device for injecting a drug
US10933636B2 (en) * 2013-12-06 2021-03-02 Palo Alto Research Center Incorporated Print head design for ballistic aerosol marking with smooth particulate injection from an array of inlets into a matching array of microchannels
US9528925B2 (en) 2014-02-14 2016-12-27 Palo Alto Research Center Incorporated Spatial modulation of light to determine object position
US9952033B2 (en) 2014-02-14 2018-04-24 Palo Alto Research Center Incorporated Spatial modulation of light to determine object length
US9207066B2 (en) 2014-02-14 2015-12-08 Palo Alto Research Center Incorporated Spatial modulation of light to determine dimensional characteristics of objects in a flow path
US10451482B2 (en) 2014-02-14 2019-10-22 Palo Alto Research Center Incorporated Determination of color characteristics of objects using spatially modulated light
US9114606B1 (en) 2014-04-07 2015-08-25 Palo Alto Research Center Incorporated Spatial light modulation method for determining droplet motion characteristics
US9400174B2 (en) 2014-04-07 2016-07-26 Palo Alto Research Center Incorporated Monitor for particle injector
EP2979714A1 (de) * 2014-08-02 2016-02-03 LTS LOHMANN Therapie-Systeme AG Nadellose Injektionsvorrichtung aufweisend eine Membran
US10039885B2 (en) * 2015-02-09 2018-08-07 Palo Alto Research Center Incorporated System and method for enhancing particle delivery to biological tissue
US10449297B2 (en) * 2015-02-09 2019-10-22 Palo Alto Research Center Incorporated Alignment of elongated particles in a particle delivery device
EP3338835A1 (en) 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medicament delivery device
US20220396811A1 (en) * 2019-11-26 2022-12-15 Georgia Tech Research Corporation Systems and Devices for Delivering Cargo Material and Methods of Delivering Cargo Materials

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
CA2158733C (en) * 1994-01-21 2007-01-16 Dennis E. Mccabe Gas driven gene delivery instrument
US5899880A (en) 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
GB9416663D0 (en) * 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US6893664B1 (en) 1996-06-17 2005-05-17 Powderject Research Limited Particle delivery techniques
CA2259194C (en) 1996-07-05 2007-06-19 Orion Corporation Transdermal compositions containing levosimendan
GB9705292D0 (en) * 1997-03-14 1997-04-30 Weston Medical Ltd Multidose injector
US5947928A (en) 1997-06-19 1999-09-07 Mile Creek Capital, Llc Drug delivery system
EP0888790A1 (en) 1997-07-04 1999-01-07 PowderJect Research Limited Drug particle delivery device
US6116718A (en) 1998-09-30 2000-09-12 Xerox Corporation Print head for use in a ballistic aerosol marking apparatus
AU765843B2 (en) 1999-04-16 2003-10-02 Powderject Research Limited Needleless syringe
ATE342089T1 (de) * 1999-06-02 2006-11-15 Boston Scient Ltd Arzneimittelabgabevorrichtungen
FR2796289B1 (fr) * 1999-07-16 2001-08-10 Cross Site Technologies Seringue sans aiguille avec injecteur a elements superposes
US6706032B2 (en) * 2000-06-08 2004-03-16 Massachusetts Institute Of Technology Localized molecular and ionic transport to and from tissues
US7597692B2 (en) 2000-06-08 2009-10-06 Massachusetts Institute Of Technology Microscission processes and procedures
GB0100756D0 (en) 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
GB2379390B (en) * 2001-09-11 2005-01-26 Caretek Medical Ltd A novel drug delivery technology
US20050040260A1 (en) * 2003-08-21 2005-02-24 Zhibo Zhao Coaxial low pressure injection method and a gas collimator for a kinetic spray nozzle
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof

Also Published As

Publication number Publication date
EP2514477A1 (en) 2012-10-24
US8388569B2 (en) 2013-03-05
JP2012223562A (ja) 2012-11-15
US20120271221A1 (en) 2012-10-25
EP2514477B1 (en) 2020-07-29

Similar Documents

Publication Publication Date Title
JP5883330B2 (ja) コリメートされたガス流及び粒子源を用いる送達機器及び方法
ES2760973T3 (es) Dispositivos de administración de fluido
JP5883334B2 (ja) コリメートされたガス流及び薬剤リザーバを用いる薬剤送達機器及び方法
US8251958B2 (en) Medicament microdevice delivery system, cartridge and method of use
EP1471953B1 (en) Gas pressure actuated microneedle arrays, and systems and methods relating to same
US20030208167A1 (en) Microneedle drug delivery device
JP4842807B2 (ja) カートリッジ付きの医薬マイクロデバイス給送システム
JP2010005411A (ja) 針無しシリンジ
JP2007051160A (ja) 超音速ガス流を使用する粒子送達のための無針注射器
US12115354B2 (en) Alignment of elongated particles in a particle delivery device
JP2012223560A (ja) コリメートされたガス流及び放出活性化テープを用いる薬剤送達機器及び方法
US10039885B2 (en) System and method for enhancing particle delivery to biological tissue
Kumar et al. Microneedle Drug Delivery System

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150326

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150326

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20150326

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20150427

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150512

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150812

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150908

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151124

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160112

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160205

R150 Certificate of patent or registration of utility model

Ref document number: 5883330

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250