JP5795737B2 - 単離された成人糸球体由来多能性間葉系幹細胞（ｈＧＬ−ＭＳＣ）、それらを製造する方法および腎臓の再生医療におけるそれらの使用 - Google Patents

単離された成人糸球体由来多能性間葉系幹細胞（ｈＧＬ−ＭＳＣ）、それらを製造する方法および腎臓の再生医療におけるそれらの使用 Download PDF

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JP5795737B2
JP5795737B2 JP2011535090A JP2011535090A JP5795737B2 JP 5795737 B2 JP5795737 B2 JP 5795737B2 JP 2011535090 A JP2011535090 A JP 2011535090A JP 2011535090 A JP2011535090 A JP 2011535090A JP 5795737 B2 JP5795737 B2 JP 5795737B2
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ジョヴァンニ・カムッシ
ステファニア・ブルーノ
ベネデッタ・ブッソラーティ
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フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング
フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0687—Renal stem cells; Renal progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources

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JP2011535090A 2008-11-04 2009-11-02 単離された成人糸球体由来多能性間葉系幹細胞（ｈＧＬ−ＭＳＣ）、それらを製造する方法および腎臓の再生医療におけるそれらの使用 Active JP5795737B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08425708A EP2186883A1 (en) 2008-11-04 2008-11-04 An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney
EP08425708.8 2008-11-04
PCT/EP2009/064468 WO2010052192A1 (en) 2008-11-04 2009-11-02 An isolated multipotent mesenchymal stem cell from human adult glomeruli (hgl-msc), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney

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JP2012507304A JP2012507304A (ja) 2012-03-29
JP2012507304A5 JP2012507304A5 (enExample) 2012-12-20
JP5795737B2 true JP5795737B2 (ja) 2015-10-14

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US (1) US9499796B2 (enExample)
EP (2) EP2186883A1 (enExample)
JP (1) JP5795737B2 (enExample)
CN (1) CN102292434B (enExample)
ES (1) ES2580172T3 (enExample)
PL (1) PL2361303T3 (enExample)
WO (1) WO2010052192A1 (enExample)

Families Citing this family (14)

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Publication number Priority date Publication date Assignee Title
EP2363136A1 (en) 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
US10077442B2 (en) 2010-05-12 2018-09-18 Inregen Bioactive renal cells
EP2611906B1 (en) * 2010-08-31 2024-01-03 Gallant Pet, Inc. Systemic, allogenic stem cell therapies for treatment of diseases in cats and dogs
EP2655602B1 (en) * 2010-12-22 2019-01-23 The Administrators of the Tulane Educational Fund Method for identifcation and culture of multipotent mesenchymal stem cells with high proliferation potential
CN104508124B (zh) 2011-07-06 2017-11-17 细胞治疗有限公司 中胚层谱系祖细胞
WO2013049856A2 (en) * 2011-09-30 2013-04-04 Hare Joshue M Renal stem cells isolated from kidney
KR102215476B1 (ko) 2012-10-24 2021-02-17 인리젠 신장 세포 모집단 및 이의 용도
WO2014113704A2 (en) * 2013-01-18 2014-07-24 Escape Therapeutics, Inc. Enhanced differentiation of mesenchymal stem cells
CN104977414B (zh) * 2014-04-09 2016-09-28 上海交通大学医学院 鉴定骨髓中是否存在保护白血病干细胞微环境的试剂盒及其应用
CA2958533C (en) * 2014-08-21 2023-03-14 Ajinomoto Co., Inc. Culture medium for mesenchymal stem cells
US20180059109A1 (en) * 2016-08-31 2018-03-01 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
CN106265745A (zh) * 2016-09-30 2017-01-04 广州赛莱拉干细胞科技股份有限公司 一种干细胞制剂及其在制备治疗慢性肾炎的药物中的应用
JP7072777B2 (ja) * 2018-07-03 2022-05-23 株式会社生命科学インスティテュート 慢性腎障害治療のための多能性幹細胞
CN117871216B (zh) * 2024-03-12 2024-06-04 中日友好医院(中日友好临床医学研究所) 一种石蜡标本中肾小球裂隙膜的三维可视化方法

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JP4085410B2 (ja) * 2003-03-14 2008-05-14 株式会社 バイオリンクインク 腎臓幹細胞／前駆細胞、腎臓幹細胞／前駆細胞の分離方法、及び腎疾患の治療方法
ITFI20060099A1 (it) * 2006-04-28 2007-10-29 Azienda Ospedaliera Careggi Popolazione di cellule staminali renali, sua identificazione ed uso per finalita' terapeutiche
DK2078073T3 (da) * 2006-10-12 2013-10-28 Ethicon Inc Nyreafledte celler og fremgangsmåder til anvendelse deraf til vævsreparation og -regenerering

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CN102292434B (zh) 2014-03-12
EP2186883A1 (en) 2010-05-19
ES2580172T3 (es) 2016-08-19
US9499796B2 (en) 2016-11-22
EP2361303B8 (en) 2016-08-10
EP2361303B1 (en) 2016-04-06
PL2361303T3 (pl) 2016-10-31
EP2361303A1 (en) 2011-08-31
WO2010052192A1 (en) 2010-05-14
US20110256111A1 (en) 2011-10-20
CN102292434A (zh) 2011-12-21
JP2012507304A (ja) 2012-03-29

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