JP5656406B2 - 治療効力を予測するためのマーカーとしての活性化ｈｅｒ３ - Google Patents

治療効力を予測するためのマーカーとしての活性化ｈｅｒ３ Download PDF

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JP5656406B2
JP5656406B2 JP2009538639A JP2009538639A JP5656406B2 JP 5656406 B2 JP5656406 B2 JP 5656406B2 JP 2009538639 A JP2009538639 A JP 2009538639A JP 2009538639 A JP2009538639 A JP 2009538639A JP 5656406 B2 JP5656406 B2 JP 5656406B2
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her3
receptor
antibody
tumor
phosphorylated
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JP2010510784A5 (enExample
JP2010510784A (ja
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ローテ マイク
ローテ マイク
トレーダー マルティン
トレーダー マルティン
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Daiichi Sankyo Europe GmbH
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • G01N2333/91—Transferases (2.)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
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JP2009538639A 2006-11-28 2007-11-28 治療効力を予測するためのマーカーとしての活性化ｈｅｒ３ Active JP5656406B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86124306P 2006-11-28 2006-11-28
EP06024658 2006-11-28
US60/861,243 2006-11-28
EP06024658.4 2006-11-28
PCT/EP2007/010335 WO2008064884A1 (en) 2006-11-28 2007-11-28 Activated her3 as a marker for predicting therapeutic efficacy

Publications (3)

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JP2010510784A JP2010510784A (ja) 2010-04-08
JP2010510784A5 JP2010510784A5 (enExample) 2011-01-20
JP5656406B2 true JP5656406B2 (ja) 2015-01-21

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US (2) US20100047829A1 (enExample)
EP (2) EP2518508A1 (enExample)
JP (1) JP5656406B2 (enExample)
AU (1) AU2007324868B2 (enExample)
CA (1) CA2670522C (enExample)
WO (1) WO2008064884A1 (enExample)

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BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
HRP20131113T1 (hr) 2007-02-16 2014-01-17 Merrimack Pharmaceuticals, Inc. Protutijela protiv erbb3 i njihova uporaba
PE20090681A1 (es) 2007-03-02 2009-06-10 Genentech Inc Prediccion de respuesta a un inhibidor her
BRPI0813583A2 (pt) 2007-07-13 2014-12-30 Prometheus Lab Inc Métodos para selecionar um medicamento anticâncer, para identificar a resposta de um tumor pulmonar, e para prognosticar a resposta de um paciente, e, arranjo
CN103399144B (zh) 2008-02-25 2015-10-28 雀巢产品技术援助有限公司 用抗体阵列选择乳腺癌治疗药物
EP2138511A1 (en) * 2008-06-27 2009-12-30 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. HER3 as a determinant for the prognosis of melanoma
BRPI0917871A2 (pt) 2008-08-15 2017-06-20 Merrimack Pharmaceuticals Inc agente terapêutico anti-erbb3 para uso em terapia de um tumor, métodos para predizer responsividade de um tumor de um agente terapêutco anti-erbb3, para selecionar terapia anti-erbb3 para um paciente, para predizer a resposta de células ao tratamento com um agente terapêutico, para identificar um biomarcador, e para evitar administração de uma droga para câncer anti-erbb3, e, kit para predizer a resposta das células ao tratamento com um agente terapêutico
EP2352851A1 (en) 2008-11-12 2011-08-10 The United States Of America, As Represented By The Secretary, Department of Health and Human Services Use of erbb4 as a prognostic and therapeutic marker for melanoma
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AU2007324868B2 (en) 2014-03-20
EP2097754B2 (en) 2018-01-24
AU2007324868A1 (en) 2008-06-05
US20160161491A1 (en) 2016-06-09
EP2097754B1 (en) 2015-01-07
JP2010510784A (ja) 2010-04-08
CA2670522C (en) 2018-08-07
US10365283B2 (en) 2019-07-30
EP2518508A1 (en) 2012-10-31
WO2008064884A1 (en) 2008-06-05
EP2097754A1 (en) 2009-09-09
US20100047829A1 (en) 2010-02-25
CA2670522A1 (en) 2008-06-05

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