JP5643460B1 - Eyelid interior tools - Google Patents

Abstract

An object of the present invention is to provide a wearer with a stable foreign body insertion feeling without giving a foreign object insertion feeling. An eyelid interior device 100 includes a C-shaped main body 10 having arcuate portions 11 and 12 and a U-shaped connecting portion 15 that avoids a small band on the inner ear side. The connecting portion 15 applies a mutual repulsive force upward to the arc-shaped portion 11 and downward to the arc-shaped portion 12. With such a structure, the eyelid interior device 100 is stably held in the eyelid sac. [Selection] Figure 1

Description

  The present invention relates to an eyelid interior device suitable for application to an ophthalmic drug delivery system (hereinafter referred to as DDS) that automatically exudes a drug to a site including the eyeball and conjunctiva.

  In recent years, the development of “punctum plug type DDS” and “contact lens type DDS” has been promoted in Japan and overseas. The punctal plug type DDS is a method in which a DDS plug containing a drug (hereinafter referred to as a punctal plug) is worn on the punctal points above and below the left and right eyes, and the drug is exuded from the punctal plug ( (See Patent Documents 1 to 3).

  Some punctal plugs as disclosed in Patent Documents 1 to 3 contain an active agent (medicine). By gradually releasing this active agent into the eye, it can be used for the treatment of glaucoma and the like.

  Further, as described in Patent Document 4, the contact lens type DDS is a method in which a contact lens body is impregnated with a drug and the drug is gradually released into the eye.

  Patent Document 5 describes an arc-shaped ophthalmic DDS device, and describes that the device is worn on a lower capsular sac and the drug is exuded to a site including the eyeball and conjunctiva.

  In Non-Patent Document 1, an annular (ring-shaped) DDS device (hereinafter referred to as a scleral ring device) is attached to the sclera (white eye) around the cornea and exudes a drug from the scleral ring device. A method is described.

JP 2008-049129 A JP 2008-018234 A JP 2008-006287 A Special table 2012-511395 gazette US Pat. No. 3,916,899 specification

(Seed Co., Ltd.), “Scleral Ring Device”, [online], [Search July 15, 2014] Internet, <URL: www.seed.co.jp/company/ir/images/2012ir.pdf>

By the way, the eyelid interior device according to the conventional example has the following problems.
(I) According to the punctal plug type DDS as seen in Patent Documents 1 to 3, the punctum is originally blocked as the first outlet for the tears to pass through the nasolacrimal duct to the nose. Interferes with normal tear flow.

(Ii) In the case of a contact lens type DDS as seen in Patent Document 4, it is difficult to slowly release a drug with a stable concentration by those who have a lot of tears and who do not. In addition, depending on the medicine, it may be considered that the medicine itself is altered by light being directly irradiated onto the medicine of the contact lens type DDS body.

(iii) According to the annular eyelid interior device described in Non-Patent Document 1, the circular arc portion of the main body hits the small band present on the conjunctival sac ear side of the wearer, and gives the wearer a feeling of foreign object insertion. It is expected that. In addition, when it is annular, there is a problem that the main body portion rotates and the main body portion cannot be stably mounted between the outer peripheral edge portion of the cornea and the heel side base portion. Thereby, there exists a problem that the utilization as a mounting member of DDS becomes difficult.

  Therefore, the present invention has been created in view of the above-described problems, and can stably fix the medicine container in the eyelid of the wearer without giving the wearer a foreign object insertion feeling, An object of the present invention is to provide an eyelid interior device that can be constructed as a DDS having a large capacity and can be used as a DDS attachment member.

  In order to solve the above-described problem, the eyelid interior device according to claim 1 includes a C-shaped main body that can be worn in the eyelid, and the main body includes an upper end of the outer peripheral edge of the cornea and an upper capsular bag. A first arcuate part that can be in contact with the base part, a second arcuate part that can be in contact with the lower end of the outer peripheral edge of the cornea and the base part of the lower capsular bag, and a first arc shape A U-shaped connecting portion that connects the first arc-shaped portion and the second arc-shaped portion, and a repulsive force is applied to the first arc-shaped portion and the second arc-shaped portion by the connecting portion.

  According to the eyelid interior device according to claim 1, the U-shaped connecting portion is fitted to the position where the wearer's small band is avoided, so that the backbone is located between the upper heel sac root portion and the lower heel sac root portion. The body can be worn in a stable state.

  The eyelid interior tool according to claim 2 is the eyelid interior tool according to claim 1, wherein the connecting portion is sized to surround the small band on the eyelid ear side.

  The eyelid interior tool according to claim 3 is the eyelid interior tool according to claim 2, wherein each of the free end portions of the first arc-shaped portion and the second arc-shaped portion is rounded.

  The eyelid interior device according to claim 4 is the eyelid interior device according to claim 3, wherein at least one of the first arc-shaped portion and the second arc-shaped portion is a hollow tubular body, and the medicine injected into the hollow tubular body is the eyelid. It is made to ooze out.

  The eyelid interior device according to claim 5 is the eyelid interior device according to claim 3, wherein at least one of the first arc-shaped portion and the second arc-shaped portion is composed of a porous impregnating member, and the impregnating agent in the impregnating member However, it is designed to exude into the eyelids.

  The eyelid interior device according to claim 6 is a C-shaped main body according to any one of claims 1 to 3, which can be worn in the eyelid, and a predetermined width attached to the main body. And a drug container that stores a predetermined amount of drug in an arcuate piece.

  According to a seventh aspect of the present invention, in the eyelid interior device according to the sixth aspect, the medicine container is attached to at least one of the first arc-shaped portion and the second arc-shaped portion of the main body.

  The eyelid interior device according to claim 8 is the engagement member according to claim 7, wherein the medicine container has a concave shape for engaging and fixing to at least one of the first arc-shaped portion and the second arc-shaped portion. It has a joint.

  The eyelid interior device according to claim 9 is the eyelid interior device according to claim 8, wherein at least one of the first arc-shaped portion and the second arc-shaped portion constituting the backbone main body engages and fixes the drug container. For this reason, it is formed into a figure of 8.

  According to the eyelid interior device according to the present invention, the two arc-shaped portions are provided with a C-shaped main body that repels up and down, and the U-shaped connecting portion of the main body is positioned to avoid the wearer's small band. By aligning, the main body can be fixed in a stable posture between the upper heel sac root and the lower heel sac root.

  With this function, the wearer can wear the main body in the eyelid without feeling a foreign object insertion. In addition, since the connecting portion is configured to be caught by the small band, rotation of the main body in the conjunctival sac can be prevented.

  According to the eyelid interior tool of the present invention, the drug container attached to the backbone main body according to the present invention is provided.

  With this configuration, the drug can be automatically exuded into the eyelid from the drug container of the main body fixed between the root part of the upper eyelid sac and the root part of the lower eyelid sac. Moreover, not only can a large amount of medicine be stored as compared with the conventional system, but the medicine container is not exposed to the outside of the eye, so that the medicine does not undergo alteration due to light and concentration change due to drying. If a hollow body is used as the medicine container, the liquid medicine can be used as it is. If the medicine container is removable, only the medicine container can be replaced, and the main body can be used as it is. If the drug is contained in the main body itself, the uncomfortable feeling given to the wearer can be further reduced.

  As a result, the eyelid interior tool can be sufficiently used as a mounting member for a large-capacity DDS that automatically supplies a medicine for a region including the eyeball and the conjunctiva.

FIGS. 2A and 2B are plan views showing a configuration example and a wearing example of the eyelid interior device 100 as the first embodiment according to the present invention. FIGS. 3 is a cross-sectional view showing an example of wearing the eyelid interior device 100. FIG. A and B are the top view and X1-X1 arrow sectional drawing which show the structural example of the eyelid interior tool 200 as 2nd Embodiment. A and B are a plan view and an X2-X2 arrow sectional view showing a configuration example of the medicine container 2. It is a top view which shows the example of wearing of the eyelid interior tool 200. FIG. It is sectional drawing which shows the example of wearing of the eyelid interior tool 200. FIG. A and B are the top view and X3-X3 arrow sectional drawing which show the structural example of the eyelid interior tool 300 as 3rd Embodiment. It is sectional drawing which shows the example of wearing of the eyelid interior tool 300. FIG.

Next, the eyelid interior tool according to the present invention will be described with reference to the drawings.
<First Embodiment>
1A, the eyelid interior device 100 of the present invention includes a C-shaped main body 10 that can be worn in the eyelid. The reason for adopting the C shape is to prevent the main body 10 from being exposed outside the eye. The main body 10 has a loop shape with one end open, and includes a lower chord-shaped first arc-shaped portion 11, an upper chord-shaped second arc-shaped portion 12, and a U-shaped connecting portion 15.

The arcuate portion 11 can contact between the upper end of the outer peripheral edge of the wearer's cornea and the base of the upper lid 51a on the back side of the upper eyelid 55 in the plan view when the main body is worn as shown in FIG. 1B. It has a circular arc shape. The arcuate part 12 has an arcuate shape that can abut between the lower end of the outer peripheral edge of the cornea surface and the root of the lower lid 51b on the back side of the lower eyelid 56. The free end portions of the arc-shaped portions 11 and 12 are rounded so as not to damage the eye.

  The connection part 15 comprises the part which connects the arc-shaped part 11 and the arc-shaped part 12, and is made into the magnitude | size which surrounds the small band 57 in the eyelid ear side shown to FIG. 1B. The small band 57 exists in the boundary of the ear side of the upper capsular sac 51a and the lower capsular sac 51b in the human conjunctiva. The connection part 15 is recessed inside the virtual outer periphery when the arcuate parts 11 and 12 are continuous. The connecting portion 15 is configured to impart a mutual repulsive force upward to the arc-shaped portion 11 and downward to the arc-shaped portion 12 as indicated by a white arrow in the figure.

  The cross-sectional shape of the arc-shaped parts 11 and 12 is a perfect circle, for example. The cross-sectional shape is not limited to a perfect circle, but may be an elliptical shape, a wing shape, or a hook shape. This is because the cross repulsive force can be set more when the cross section is elliptical than the regular circle. An elliptical shape or the like is advantageous when a material with low rigidity is used.

[Material]
As the material of the main body 10, a material that can be mounted in the eye and has elasticity can be used. For example, a metal such as gold (Au) or stainless steel, a resin, glass fiber, or the like. The thickness is about 0.1 mm to 2.0 mm. In order not to hold a foreign object insertion feeling, the thickness of the main body 10 should be as thin as possible if the mutual repulsive force against the arcuate portions 11 and 12 can be secured to some extent.

[Production method]
For example, when manufacturing the main body 10 using a resin, the method for manufacturing the eyelid interior device 100 first has a C shape including an arc-shaped portion extending in two directions and a U-shaped connecting portion. Create a mold with cavity and core. The resin material to be the main body 10 is melted by heat. Next, in a sterile state, the molten resin material is poured into a mold and thermoformed. Then cool and harden. Thereby, the eyelid interior tool 100 of the C-type main body 10 having the arc-shaped portions 11 and 12 and the U-shaped connecting portion 15 can be manufactured.

[Handling method]
When the eyelid interior device 100 according to the present invention is worn in the eyelid, first, hold the backbone main body 10 shown in FIG. 1A in the hand, and in FIG. 1B, positions of the connecting portion 15 and the small band 57 in the first stage. While aligning, the arcuate portion 11 is slowly inserted toward the upper end of the outer peripheral edge of the cornea surface and the base of the upper lid 51a on the back side of the upper eyelid 55. Then, the insertion is stopped at a position where the arc-shaped portion comes into contact with the root of the upper capsular bag 51a.

  In the second stage, the arcuate portion 12 is inserted toward the lower end of the outer peripheral edge of the cornea surface and the base of the lower lid 51b on the back side of the lower eyelid 56. At this stage, as shown in FIG. 1A, a slight force is applied to the main body 10 in the direction of the white arrows (feeling of being squeezed inside). Then, the arc-shaped portion 12 is slowly inserted so that the arc-shaped portion is in contact with these base portions. Thereafter, when the force is slowly released, the posture becomes stable at a position where the arc-shaped portion comes into contact with the base portion of the lower capsular sac 51b.

  In the cross-sectional view of the human eye shown in FIG. 2, the conjunctiva is divided into an eyelid conjunctiva and an eyeball conjunctiva, both of which are folded and connected at a position deep in the eyelid. According to the eyelid interior device 100 according to the present invention, the arc-shaped portion 11 is in contact with the root portion of the upper eyelid sac 51a on the back side of the upper eyelid 55 at the back of the upper end of the outer peripheral edge of the cornea. However, the arcuate portion 12 is in contact with the root of the lower capsular sac 51b on the back side of the lower eyelid 56 at the lower end of the outer peripheral edge of the cornea. Moreover, it is fixed in a state where an appropriate tension is applied in the direction of the white arrow in the figure. Thereby, the eyelid interior tool 100 can be worn in the eyelid with good reproducibility.

  Thus, according to the eyelid interior tool 100 as the first embodiment, the C-shaped main body 10 having the arc-shaped portions 11 and 12 and the U-shaped connecting portion 15 extending in two directions is provided. The eyelid interior device 100 has a structure that applies a mutual repulsive force that is directed upward with respect to the arc-shaped portion 11 and directed downward with respect to the arc-shaped portion 12.

  With this structure, by fitting the U-shaped connecting portion 15 at a position that avoids the wearer's small band 57, the wearer can wear the main body 10 in the eyelid without feeling foreign object insertion. it can. In addition, since the concave portion of the connecting portion 15 is caught by the small band 57, the rotation of the main body 10 can be prevented.

  Thereby, the said main body 10 can fully be utilized now as a member fixing tool at the time of corneal transplantation. Further, for example, the medicine container 2 shown in FIG. 3A can be easily attached to the main body 10.

<Second Embodiment>
Subsequently, with reference to FIGS. 3 to 6, the eyelid interior device 200 as the second embodiment will be described. In the plan view shown in FIG. 3A, the eyelid interior device 200 of the present invention automatically supplies a chemical solution over a long period of time to a site including the eyeball and conjunctiva. The eyelid interior device 200 includes a C-shaped main body 20 that can be worn in the eyelid and a medicine container 2 that can be detachably attached to the main body 20. The main body 20 has arcuate portions 21 and 22 and a connecting portion 25. Since these functions and materials have been described in the first embodiment, description thereof will be omitted.

  For the main body 20, the modification of the main body 10 described in the first embodiment is used. In this modified example, the point that the cross section of the main body 20 is “8” is different from the regular circle of the main body 10 (see FIG. 3B). The eyelid interior device 200 employs a structure that can fix the drug container 2 in a stable state deep inside the eyelid conjunctival sac by using the mutual repulsive force that opens outward with the central folded portion of the main body 20 as a fulcrum. .

  3B is a cross-sectional view taken along arrow X1-X1 of the eyelid interior device 200 shown in FIG. 3A. In FIG. 3B, the cross section of the main body 20 has, for example, a “8” shape. This "8" -shaped part has a convex part 21a forming a groove part. Further, the medicine container 2 has an engaged portion 29 having a concave shape. The concave portion of the engaged portion 29 can be engaged and fixed to the convex portion 21 a of the main body 20. Of course, the cross section of the main body 20 may have a circular shape with no irregularities as in the main body 10 described in the first embodiment.

  The medicine container 2 shown in FIG. 4A can inject a liquid medicine by forming a hollow portion 23 by hollowing out the inside thereof. For example, the hollow portion 23 has an arc shape with a predetermined width, and has one or more apertures 3 for automatically exuding the injected medicine at a predetermined position. The diameter of the aperture 3 is about several μm to several 100 μm, and the drug is exuded little by little through the aperture 3. The drug is not limited to a liquid and may be in a jelly form. In addition, a method of refilling the medicine using a predetermined injector after the liquid medicine is depleted may be adopted.

  For automatic drug exudation, the penetration phenomenon is used. The permeation phenomenon is a phenomenon in which when a solution having a different concentration is in contact with a semipermeable membrane, the solvent of the low concentration solution tends to diffuse toward the high concentration solution. Semipermeable membranes have the property of not allowing solutes to pass through but solvents to pass through. The pressure at which the osmosis phenomenon occurs is called osmotic pressure. For example, the force by which water moves from the lower concentration to the higher concentration between two liquids separated by a cell membrane and having different concentrations is called osmotic pressure.

  The cross section of the medicine container 2 shown in FIG. 4B has a wing shape. The cross section is not limited to the wing shape but may be any structure that is difficult to fall off. For example, the cross section may have a circular shape, an elliptical shape, or a hook shape. Accordingly, the medicine container 2 can be easily attached to the main body 20 with good reproducibility.

  Moreover, the medicine container 2 can be detached from the main body 20 shown in FIG. 3A, and it becomes possible to repeatedly use the main body 20 by replacing only the medicine container 2. The medicine container 2 may be attached to at least one of the arcuate portions 21 and 22, and the delivery amount, concentration, and delivery speed of the medicine can be controlled by changing the attachment position and number. . These constitute the eyelid interior tool 200.

[Production method]
Next, a method for manufacturing the eyelid interior device 200 will be described. For example, when the three-piece eyelid interior tool 200 is formed, first, the main body 20 having a “8” -shaped cross section is manufactured. In this case, the above-described material is poured into a mold shaped like a C shape including a U-shaped connecting portion and molded. When the cross section is not an 8-shaped cross section, the main body 20 is processed by bending the material into a linear shape including the U-shaped connecting portion 25 regardless of the formation of the mold. The free end of the main body 20 is rounded by applying heat.

  Moreover, the method of manufacturing the chemical | medical agent container 2 produces a metal mold | die with the cavity and core which modeled the arc shape and the to-be-engaged part first, for example. Next, a terminal endless tube made of silicone resin is set in a mold under aseptic conditions, and air is blown from the other end to form an arc in a balloon shape. Thereafter, the air blowing port is closed. When introducing the medicine into the medicine container 2, for example, the inside of the medicine container 2 is kept in a vacuum state, and then an injection port for injecting the medicine is formed.

  A predetermined amount of chemical solution is injected through the injection port, and then the injection port is closed with a plug member. And the 1 or more opening part 3 shown in FIG. 4A for exuding a chemical | medical agent to a predetermined position is formed. As the plug member, the same material as that of the main body 20 can be used. Thereby, the chemical | medical solution inclusion type chemical | medical agent container 2 can be formed now.

[Handling method]
When the eyelid interior device 200 according to the present invention is worn in the eyelid, first, the two drug containers 2 shown in FIG. 3A are attached to the main body 20. In the case of two pieces, the medicine container 2 is attached to at least one of the arc-shaped portion 21 and the arc-shaped portion 22. 3A, the main body 20 with the drug container 2 shown in FIG. 3A is held in the hand, and in FIG. The arcuate portion 21 is slowly inserted toward the upper end of the upper portion and the base of the upper lid 51a on the back side of the upper eyelid 55. Then, the insertion is stopped at a position where the arc-shaped portion comes into contact with the root of the upper capsular bag 51a.

  In the second stage, the arcuate portion 22 is inserted toward the lower end of the outer peripheral edge of the cornea surface and the base of the lower capsular sac 51b on the back side of the lower eyelid 56. At this stage, a slight force is applied to the main body 20 in a predetermined direction (see the direction of the white arrow in FIG. 1A). Then, the arc-shaped portion 22 is slowly inserted so that the arc-shaped portion is in contact with these base portions. Thereafter, when the force is slowly released, the posture becomes stable at a position where the arc-shaped portion comes into contact with the base portion of the lower capsular sac 51b.

  FIG. 6 shows a cross-sectional view of the eyelid interior tool 200 worn in the eyelid. In FIG. 6, the arcuate portion 21 with the drug container 2 is in contact with the root of the upper capsular sac 51 a on the back side of the upper eyelid 55 at the upper end of the outer peripheral edge of the surface of the cornea, and the arcuate portion with the drug container 2 The arcuate portion 22 is in contact with the base portion of the lower capsular sac 51b on the back side of the lower eyelid 56 at the lower end of the outer peripheral edge of the cornea surface 22. Moreover, it is fixed in a state where an appropriate tension is applied in the direction of the white arrow in the figure. Thereby, the eyelid interior tool 200 with the medicine container 2 can be worn in the eyelid with good reproducibility.

  As described above, according to the eyelid interior device 200 as the second embodiment, the C-shaped structure main body 20 according to the present invention is used, and the medicine container 2 is detachably attached to the main body 20. Then, the eyelid interior device 200 is held on the back side of the eyelid so that the medicine is automatically exuded from the opening 3.

  With this structure, the wearer can stably wear the medicine container 2 in the eye without a foreign object insertion feeling. Compared with the conventional method, since a large amount of medicine can be accommodated in the medicine container 2, the efficacy period is prolonged. Since the medicine container 2 is hollowed, an existing medicine can be used. The wearer can wear a necessary amount of the medicine container 2. It is also possible to repeatedly use the main body 20 by replacing only the medicine container 2. Since the medicine container 2 is not exposed to the outside of the eye, the contained medicine is not affected by light alteration and concentration change due to drying.

  In this example, the cross-section of the main body 20 is in the shape of a figure 8, but this is not restrictive. As long as the medicine container 2 shown in FIG. 3A can be engaged and fixed, the cross section of the main body 20 may be circular or elliptical as in the first embodiment. Further, either one of the arc-shaped portions 21 and 22 may have a “8” -shaped cross section.

  Moreover, although the case where the chemical | medical agent container 2 was attached to the arc-shaped parts 21 and 22 was demonstrated, it is not restricted to this, A chemical | medical agent accommodation is carried out using an adhesive agent in at least one of the arc-shaped parts 21 and 22 The body 2 may be engaged and fixed, and the eyelid interior tool 200 may be made into one piece. The drug container 2 has a hollow shape and a drug is injected into it. The drug container 2 itself can be made of a porous material, and the material itself can be impregnated with the drug. is there. As a result, it becomes possible to automatically supply the medicine from the medicine container 2 into the eyelid, and it is possible to provide a general-purpose ophthalmic DDS with high reliability.

<Third Embodiment>
Subsequently, an eyelid interior tool 300 as a third embodiment will be described. In the plan view shown in FIG. 7A, the eyelid interior device 300 is stably mounted deep in the conjunctival sac using a mutual repulsive force that opens outward with the central folded portion of the main body 30 as a fulcrum. The main body 30 has a C-shaped shape including a lower chord-shaped arc portion 31, an upper chord-shaped arc-shaped portion 32, and a connecting portion 35 that connects them. The connecting portion 35 is U-shaped with a size surrounding the small band 57 on the inner ear side shown in FIG. The connecting portion 35 imparts a mutual repulsive force that is upward with respect to the arc-shaped portion 31 and downward with respect to the arc-shaped portion 32.

  The arc-shaped portions 31 and 32 are provided with hollow tubular drug containing portions 37 and 38 for containing the drug therein. The medicine accommodating portions 37 and 38 form one or more apertures 34 for exuding the medicine to a predetermined position in the eyelid. The drug is oozed into the eyelid from the opening 34 of the drug container 37 or 38.

  In the cross-sectional view shown in FIG. 7B, the cross section of the arcuate portion 32 of the main body 30 has an elliptical shape. As a result, the main body 30 reduces the feeling of foreign object insertion when it is mounted in the eyelid compared to the second embodiment. The arc-shaped portions 31 and 32 do not have to have the same cross section, and at least one of them may be hollow. The cross-sectional shape of the main body 30 may be, for example, an 8-shape, a circular shape, a wing shape, or a hook shape in addition to the elliptical shape.

  In the cross-sectional view shown in FIG. 8, the arcuate portion 31 is brought into contact with the upper end of the outer peripheral edge portion of the cornea surface and the root portion of the upper capsular bag 51a. The arc-shaped portion 32 is brought into contact with the lower end of the outer peripheral edge of the cornea surface and the root of the lower capsular sac 51b.

[Material]
As the material of the main body 30, a material that can be mounted in the eyelid and has elasticity can be used as in the second embodiment. As described above, the osmosis phenomenon is used for the automatic exudation of the medicine.

[Production method]
In the method of manufacturing the eyelid interior device 300, for example, first, a mold is formed with a cavity and a core shaped like a C shape including a U-shaped connecting portion in order to form the main body 30. Next, a raw material such as a pipe of the main body 30 is set in a mold under aseptic conditions, and air is blown from the other end to form a balloon. Thereafter, the air blowing port is closed. Thereby, the main body 30 is obtained.

  If the main body 30 can be formed, when the drug is introduced into the main body 30, the inside of the drug containing portions 37 and 38 is once held in a vacuum state, and then an injection port for injecting a chemical solution is formed.

  A predetermined amount of chemical solution is injected through the injection port, and then the injection port is closed with a plug member. Then, one or more openings 34 for exuding the drug at a predetermined position are formed. As the plug member, the same material as the material of the main body 30 can be used. As a result, the eyelid interior device 300 having the chemical solution-containing main body 30 can be manufactured.

  Thus, according to the eyelid interior device 300 as the third embodiment, the C-shaped main body 30 having the U-shaped connecting portion 35 that avoids the small band 57 shown in FIG. 5 is provided. The main body 30 includes drug storage units 37 and 38 that store drugs. The eyelid interior device 300 has a structure that is held on the back side of the eyelid and automatically exudes the medicine from the opening 34.

  With this structure, the amount of medicine to be stored is reduced as compared with the second embodiment, but the wearer can stably wear the eyelid interior device 300 in the eye without a foreign object insertion feeling. Since the medicine containing portions 37 and 38 are hollow, the existing medicine can be injected and used as it is. Since the medicine containing portions 37 and 38 are not exposed to the outside, the contained medicine is not subjected to alteration due to light and concentration change due to drying. The drug container 2 shown in FIG. 3A can also be attached to the main body 30. Thereby, a chemical | medical agent accommodation amount can be increased.

  In the third embodiment, the arc-shaped portions 31 and 32 are hollow tubular bodies. However, at least one of the arc-shaped portions 31 and 32 is formed of a porous impregnating member, and the impregnating agent in the impregnating member is applied to the eyelid. You may make it ooze. In this case, as the material of the arc-shaped portions 31 and 32, a material that can be mounted in the eyelid and has elasticity can be used as in the second and third embodiments. The arc-shaped portions 31 and 32 formed of the impregnating member do not need to be hollow tubular and can be used in the form of a sheet, so that the foreign object insertion feeling given to the wearer can be further reduced.

  INDUSTRIAL APPLICABILITY The present invention is extremely suitable when applied to an ophthalmic DDS that automatically supplies a chemical solution to a site including the eyeball and conjunctiva.

1, 20, 30 Main body 2 Drug container 3, 34 Opening portion 23 Hollow portion 15, 25, 35 Connection portion 29 Engaged portion 37, 38 Drug storage portion 11, 12, 21, 22, 31, 32 Arc shape Part 100, 200, 300 Eyelid interior tool

Claims (9)

It has a C-shaped main body that can be worn in the eyelid,
The backbone body is
A first arcuate portion capable of contacting between the upper end of the outer peripheral edge of the surface of the cornea and the root of the upper capsular bag;
A second arcuate portion capable of abutting between the lower end of the outer peripheral edge of the surface of the cornea and the base of the lower capsular bag;
A U-shaped connecting portion that connects the first arc-shaped portion and the second arc-shaped portion, and a repulsive force is applied to the first arc-shaped portion and the second arc-shaped portion by the connecting portion; Eyelid interior tools. The connecting portion is
The eyelid interior device according to claim 1, which is sized to surround a small band on the eyelid ear side.   The eyelid interior device according to claim 2, wherein the free end portion of each of the first arc-shaped portion and the second arc-shaped portion is rounded. At least one of the first arc-shaped part and the second arc-shaped part is
A hollow tubular body,
The eyelid interior device according to claim 3, wherein the medicine injected into the hollow tubular body exudes to the eye surface. At least one of the first arc-shaped part and the second arc-shaped part is
It is composed of a porous impregnated member,
The eyelid interior device according to claim 3, wherein the impregnated drug in the impregnated member exudes the drug to the eye surface. A C-shaped main body according to any one of claims 1 to 3, which can be worn in the eyelid;
An eyelid interior device comprising: a medicine container that contains a predetermined amount of medicine in an arc-shaped piece having a predetermined width attached to the main body. The eyelid interior device according to claim 6, wherein the medicine container is attached to at least one of the first arc-shaped portion and the second arc-shaped portion of the main body. The drug container is
The eyelid interior device according to claim 7, further comprising an engaged portion having a recessed shape for engaging and fixing with at least one of the first arc-shaped portion and the second arc-shaped portion.   9. The cross section of at least one of the first arc-shaped portion and the second arc-shaped portion constituting the backbone main body has an 8-shaped cross section for engaging and fixing the drug container. Eyelid interior tools.

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