JP5607916B2 - Sunscreen cosmetics - Google Patents

Description

  The present invention relates to a sunscreen cosmetic. More specifically, the present invention relates to a sunscreen cosmetic that exhibits a high SPF value and at the same time has excellent usability such as a fresh feel.

  In sunscreen cosmetics, it is necessary to add inorganic powder, organic UV absorbers, etc. to the formulation in order to provide Sun Protection Factor (SPF), which is an index to prevent UV rays. . In general, sunscreen cosmetics often take the form of water-in-oil emulsions or oil-in-water emulsions, and are used for suitable applications based on the characteristics of each.

  The water-in-oil emulsion has the characteristics that it can easily achieve high SPF and has excellent water resistance because it can be highly blended with oil-soluble UV absorbers and inorganic powders, but it is problematic in terms of oily and sticky feeling. May occur. On the other hand, oil-in-water emulsions provide a fresh feeling of use, but oil-soluble UV absorbers and inorganic powders cannot be blended in high amounts, and water-soluble UV absorbers do not function well in formulations and have high SPF. There was a problem that it was difficult to achieve. In addition, when trying to increase the blending amount of an oil-soluble ultraviolet absorber or the like in order to increase SPF, there is a problem that the amount of oily components in the preparation increases and the fresh feeling of use is lost.

  In connection with these problems, for example, Patent Document 1 discloses that an oil-soluble ultraviolet absorber is not highly blended, achieves both UV protection effect and stability without impairing a fresh feeling of use. As an oil-in-water emulsified sunscreen cosmetic with excellent film uniformity and usability (skin familiarity), in addition to oil-soluble and water-soluble UV absorbers, specified as water-soluble thickener (acrylic water-soluble polymer) Containing a hydrophilic nonionic surfactant.

Patent Document 2 discloses that an oil-in-water emulsified cosmetic containing a specific amount of alkylmethyl tauric acid, a water-soluble ultraviolet absorber, an oil agent, and water has an excellent UV protection effect, and has a feeling of use (no freshness or stickiness). ) And stability over time are also described.
Patent Document 3 is mainly an oil-based composition, but by itself blending an organopolysiloxane elastomer spherical powder that does not have an ultraviolet absorption effect or a scattering effect, the ultraviolet protection effect is improved and extended. It is described that the feeling of refreshment is also improved.

JP 2008-162930 A JP 2002-284638 A JP-A-8-259419

  The subject in the present invention is a sunscreen cosmetic containing a water-soluble ultraviolet absorber, from the viewpoint different from the conventional techniques including Patent Documents 1 to 3 described above, while maintaining excellent usability such as a fresh touch, An object of the present invention is to provide a cosmetic that can increase SPF.

  In order to solve the above-mentioned problems, the present inventors have intensively studied. As a result, a high SPF can be obtained by selecting and combining a combination of phenylbenzimidazolesulfonic acid, which is a water-soluble ultraviolet absorber, and a specific neutralizing agent. The inventors have found that the value can be achieved and have come to make the present invention.

That is, the present invention
(A) 0.1 to 5% by mass of phenylbenzimidazolesulfonic acid, and (b) an amount of triisopropanolamine suitable for neutralizing the phenylbenzimidazolesulfonic acid (a). Providing sunscreen cosmetics.

  The sunscreen cosmetic of the present invention can achieve a high SPF value and is excellent in use feeling such as freshness and non-stickiness. Paying attention to the neutralized salt to be blended in combination with the water-soluble ultraviolet absorber, the ultraviolet absorbing ability improving effect obtained by using a specific neutralized salt is an effect first found in the present invention.

It is a figure which shows the ultraviolet absorption spectrum when sodium hydroxide (NaOH) is used as a neutralized salt of phenylbenzimidazolesulfonic acid (solid line) and when triisopropanolamine (TIA) is used (dashed line).

  As described above, the sunscreen cosmetic of the present invention was formulated by using phenylbenzimidazole sulfonic acid as a water-soluble ultraviolet absorber, using triisopropanolamine as a neutralization salt, and selecting a specific combination thereof. It is characterized by.

  The phenylbenzimidazole sulfonic acid (component a) used in the cosmetic of the present invention has been conventionally used in cosmetics and the like as a water-soluble ultraviolet absorber, and is mainly used in the UV-B region (290-290). It is an organic compound that effectively absorbs ultraviolet rays of 320 nm). In the present invention, for example, commercially available Ortholex 232 (manufactured by Merck) or Neo Heliopan Hydro (manufactured by Simrise) can be suitably used.

  The blending amount of phenylbenzimidazolesulfonic acid in the present invention is 0.1 to 5% by mass, preferably 0.5 to 4% by mass, and more preferably 1 to 3% by mass. When the blending amount is less than 0.1% by mass, it is difficult to obtain a sufficient ultraviolet ray preventing effect. When the blending amount exceeds 5% by mass, precipitation of crystals and irritation to the skin tend to be strong.

  In the cosmetic of the present invention, triisopropanolamine (component b) is used as a neutralized salt of phenylbenzimidazolesulfonic acid. The triisopropanolamine used in the present invention may be a commercial product.

  The blending amount of triisopropanolamine in the present invention is an amount suitable for neutralizing the phenylbenzimidazolesulfonic acid. Specifically, the concentration may be about 10% above and below the concentration (mass%) serving as the neutralization point of the blended phenylbenzimidazolesulfonic acid. For example, when the concentration serving as the neutralization point is 3% by mass, the concentration is within the range of 2.7% by mass to 3.3% by mass.

The cosmetic of the present invention is required to contain triisopropanolamine as a neutralization salt, but in addition to that, it excludes the addition of conventionally used neutralization salts such as NaOH and KOH. is not. When it contains other neutralization salt, the total compounding quantity of these other neutralization salt and triisopropanolamine should just be an amount suitable for neutralizing phenylbenzimidazolesulfonic acid.
In addition, in the case where the cosmetic of the present invention contains a component to be neutralized with a neutralization salt (alkali source) in addition to phenylbenzimidazolesulfonic acid, and further contains another neutralization salt, Needless to say, the total amount of triisopropanolamine and other neutralized salts is the amount necessary to neutralize the entire system. In that case, a part of the other neutralized salt may contribute to the neutralization of phenylbenzimidazolesulfonic acid, and the total amount of the other neutralized salt and the triisopropanolamine is the amount of phenylbenz The amount is suitable for neutralizing imidazolesulfonic acid.

  The cosmetic of the present invention is preferably provided as an aqueous composition or an oil-in-water emulsion composition in order to ensure a fresh and refreshing feeling of use. In the cosmetic of the present invention, SPF based on a water-soluble ultraviolet absorber is remarkably improved by blending a specific neutralizing agent, so that it is not necessary to blend an oil-soluble ultraviolet absorber as in the prior art. . However, it does not exclude the addition of oil-soluble UV absorbers, but by further adding oil-soluble UV absorbers, additional effects such as further improvement of SPF and enhancement of UV-absorbing ability in the UV-A region. Can be obtained.

  The oil-soluble ultraviolet absorber that can be blended in the cosmetic of the present invention is not particularly limited. For example, paraaminobenzoic acid (PABA), PABA monoglycerin ester, N, N-dipropoxy PABA ethyl ester, N, N -Benzoic acid UV absorbers such as diethoxy PABA ethyl ester, N, N-dimethyl PABA ethyl ester, N, N-dimethyl PABA butyl ester, diethylaminohydroxybenzoyl hexyl benzoate; anthranyl such as homomenthyl-N-acetylanthranylate Acid ultraviolet absorbers; salicylic acid type such as amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate External line absorbent: octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p- Methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, octyl-p-methoxycinnamate [= 2-ethylhexyl-p-methoxycinnamate], 2-ethoxyethyl-p-methoxycinnamate Cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate, glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, 3, Cinnamic acid UV absorbers such as 3-methyl-4- [methylbis (trimethylsiloxy) silyl] butyl 4,5-trimethoxycinnamate; 2-phenyl-5-methylbenzoxazole, 2,2 ′ -Hydroxy-5-methylphenylbenzotriazole, 2- (2'-hydroxy-5'-t-octylphenyl) benzotriazole, 2- (2'-hydroxy-5'-methylphenylbenzotriazole), dibenzalazine, dianisoylmethane 4-tert-butyl-4′-methoxydibenzoylmethane, 4- (1,1-dimethylethyl) -4′-methoxydibenzoylmethane, 5- (3,3-dimethyl-2-norbornylidene) -3- Pentan-2-one, octocrylene [= 2-cyano-3,3-diphenyl-2-propenoic acid-2-ethyl ester Sill ester], polysilicon -15 = dimethicone co diethyl benzalmalonate], and the like.

  When the oil-soluble ultraviolet absorber is blended, the blending amount is at most 1% by mass, preferably 0.5% by mass or less. If the blending amount exceeds 1% by mass, the blending amount of the oil agent for dissolving it also increases, so that the freshness tends to deteriorate not only for the whole preparation.

  The cosmetic of the present invention can be blended with other components usually used in sunscreen cosmetics and the like within a range that does not impair the effects of the present invention. For example, vitamins, fats and oils, waxes, hydrocarbon oils, higher alcohols, synthetic ester oils, silicones, humectants, anionic surfactants, cationic surfactants, amphoteric surfactants, antiseptics, anti-inflammatory agents, whitening agents, Examples include plant extracts, activators, blood circulation promoters, water-soluble polymers, thickeners, powder components, and sequestering agents.

  The dosage form of the sunscreen cosmetic of the present invention is not particularly limited, but it is preferably provided in the form of lotion, emulsion, cream or the like.

  Hereinafter, the present invention will be described in more detail with specific examples. However, the present invention is not limited to these examples. Moreover, in the following examples etc., unless otherwise indicated, the blending amount represents mass%.

(Test example)
The aqueous solution containing phenylbenzimidazolesulfonic acid (5% by mass) was neutralized by adding sodium hydroxide or triisopropanolamine.
1 mg / cm ² of each neutralized aqueous solution was applied to a substrate made of PMMA, and the absorption spectrum in the ultraviolet region was measured (measuring device: UV-4100 (manufactured by Hitachi)).
The measurement results are shown in FIG. As is apparent from the figure, when triisopropanolamine was used as the neutralization salt, the ultraviolet absorption ability was significantly improved compared to the case where NaOH was used as the neutralization salt.

Example 1
Sunscreen latex:
Compounding component amount (% by mass)
1. Ion exchange water 50
2. Acrylic acid / alkyl methacrylate copolymer (Pemulene TR-1: manufactured by Goodrich) 0.1
3. Agar 0.5
4). Potassium hydroxide 0.05
5. Dimethylpolysiloxane 3
6). Decamethylcyclopentasiloxane 4
7). Squalane 2
8). Sunflower oil 1
9. Ethanol 5
10. Glycerin 6
11.1,3-butylene glycol 5
12 Polyoxyethylene methyl glucoside 3
13. Sodium hexametaphosphate 0.05
14 Hydroxypropyl-β-cyclodextrin 0.1
15. Dipotassium glycyrrhizinate 0.05
16. Loquat leaf extract 0.1
17. Sodium L-glutamate 0.05
18. Fennel extract 0.1
19. Yeast extract 0.1
20. Lavender oil 0.1
21. Giant extract 0.1
22. Xanthan gum 0.1
23. Bengala appropriate amount 24. Yellow iron oxide Paraben appropriate amount 26. Purified water residue 27. Phenylbenzimidazolesulfonic acid 3
28. Triisopropanolamine 2.3

<Manufacturing method>
(1) 1 and 2 are heated and dissolved, cooled to room temperature, and then pulverized with a homomixer to form mixture 1.
(2) Add 3 and 4 to mixture 1 to form mixture 2.
(3) 8-28 is added to the mixture 2 at room temperature and mixed to obtain a mixture 3.
(4) Add 5-7 to the mixture 3 at room temperature and emulsify with a homomixer to obtain the desired product.

(Example 2)
Sunscreen lotion:
Compounding component amount (% by mass)
1. Ion exchange water 50
2. Glycerin 1
3. Agar 0.5
4.1,3-Butylene glycol 5
5. Sodium hexametaphosphate 0.03
6). Trimethylglycine 1
7). Sodium polyaspartate 0.1
8). α-tocopherol 2-L-ascorbic acid potassium phosphate diester 0.1
9. Thiotaurine 0.1
10. Green tea extract 0.1
11. Western mint extract 0.1
12 Iris root extract 0.1
13. EDTA3 sodium 0.1
14 Purified water residue 15. Ethyl alcohol 5
16. POE, POP decyl tetradecyl ether 0.2
17. Phenoxyethanol appropriate amount 18. Perfume proper amount19. Phenylbenzimidazolesulfonic acid 3
20. Triisopropanolamine 2.3

<Manufacturing method>
(1) 1 and 2 are heated and dissolved, cooled to room temperature, and then pulverized with a homomixer to form mixture 1.
(2) 3 to 15 are mixed with the mixture 1 at room temperature to obtain a mixture 2.
(3) After mixing 16 to 18 at room temperature, the mixture is added to mixture 2 to form mixture 3.
(4) 19 and 20 are added to the mixture 3 at room temperature to obtain the desired product.

(Example 3)
Lotion:
Compounding component amount (% by mass)
1. Ion exchange water 50
2. Ethanol 10
3. Agar 0.5
4). Dipolopylene glycol 1
5. Polyethylene glycol 1000 1
6). Polyoxyethylene methyl glucoside 1
7). Jojoba oil 0.01
8). Glyceryl tri-2-ethylhexanoate 0.1
9. Polyoxyethylene hydrogenated castor oil 0.2
10. Polyglyceryl diisostearate 0.15
11. N-stearoyl-L-glutamate sodium 0.1
12 Citric acid 0.05
13. Sodium citrate 0.2
14 Sodium hydroxide 0.4
15. Dipotassium glycyrrhizinate 0.1
16. Arginine hydrochloride 0.1
17. L-ascorbic acid 2-glucoside 2
18. Ogon Extract 0.1
19. Yukinoshita extract 0.1
20. Nettle extract 0.1
21. Tranexamic acid 1
22. Edetate trisodium 0.05
23. 2-Ethylhexyl paramethoxycinnamate 0.01
24. Dibutylhydroxytoluene Suitable amount 25. Paraben appropriate amount 26. Deep sea water 3
27. Purified water Residual 28. Perfume appropriate amount29. Phenylbenzimidazolesulfonic acid 3
30. Triisopropanolamine 2.3

<Manufacturing method>
(1) 1 and 2 are heated and dissolved, cooled to room temperature, and then pulverized with a homomixer to form mixture 1.
(2) 3-11, 23-25 and 28 are heated and dissolved at 70 ° C. and added to mixture 1 to form mixture 2.
(3) 12-22, 26, 27, 29 and 30 are mixed and dissolved at room temperature and added to the mixture 2 to obtain the desired product.

Example 4
Sunscreen latex:
Compounding component amount (% by mass)
1. Ion exchange water 50
2. Carboxyvinyl polymer 0.1
3. Agar 0.5
2. Ion exchange water 50
3. Carboxyvinyl polymer 0.1
4). Potassium hydroxide appropriate amount 5. Dimethylpolysiloxane 2
6). Behenyl alcohol 1
7). Batyl alcohol 0.5
8). Squalane 6
9. Tetra-2-ethylhexanoic acid pentaerythlit 2
10. Polyoxyethylene glyceryl isostearate 1
11. Polyoxyethylene glyceryl monostearate 1
12 Hardened oil 3
13. Glycerin 5
14.1,3-Butylene glycol 7
15. Erythritol 2
16. Sodium hexametaphosphate 0.05
17. Phenoxyethanol appropriate amount 18. Phenylbenzimidazolesulfonic acid 3
19. Triisopropanolamine 2.3
20. Purified water residue

<Manufacturing method>
(1) 1 and 2 are heated and dissolved, cooled to room temperature, and then pulverized with a homomixer to form mixture 1.
(2) Add 3 and 4 to mixture 1 to form mixture 2.
(3) After 5 and 12 are heated and dissolved, the mixture is added to the mixture 2 and emulsified with a homomixer to obtain an emulsion 1.
(4) Add 13-20 to Emulsion 1 to obtain the desired product.

(Example 5)
Sunscreen cream:
Compounding component amount (% by mass)
1. Ion exchange water 50
2. Bentonite 1
3. Agar 0.5
4). Stearic acid 1
5. Palmitic acid 1
6). Glyceryl tri-2-ethylhexanoate 3
7. Cetyl 2-ethylhexanoate 2
8). Polyoxyethylene glyceryl isostearate 1
9. Glycerol monostearate 1
10. Polyoxyethylene glyceryl monostearate 1
11.4-t-butyl-4′-methoxy-
Dibenzoylmethane 1
12 2-methoxyhexyl paramethoxycinnamate 7
13. Eicosene / vinylpyrrolidone copolymer 2
14 Fine particle tyrene oxide (30 nm) 2
15. Sodium hexametaphosphate 0.1
16. Phenoxyethanol appropriate amount17. Edetate trisodium appropriate amount 18. Dipropylene glycol 5
19. Purified water Residual 20. Perfume appropriate amount 21. Phenylbenzimidazolesulfonic acid 3
22. Triisopropanolamine 2.3

<Manufacturing method>
(1) 1 and 2 are heated and dissolved, cooled to room temperature, and then pulverized with a homomixer to form mixture 1.
(2) Add 3 to the mixture 1 and disperse with a homomixer to make dispersion 1.
(3) After 4 to 13 are heated and dissolved, they are added to the heated dispersion 1 and emulsified with a homomixer to obtain an emulsion 1.
(4) Add 14 and 15 to Emulsion 1 and disperse with a homomixer to make Dispersion 2.
(5) Add 16-22 to Dispersion 2, disperse with a homomixer, and cool to room temperature to obtain the desired product.

Claims (2)

(A) 0.1 to 5% by mass of phenylbenzimidazolesulfonic acid, and (b) an amount of triisopropanolamine suitable for neutralizing the phenylbenzimidazolesulfonic acid (a). To sunscreen cosmetics. The cosmetic according to claim 1, wherein the cosmetic is in the form of an aqueous composition or an oil-in-water emulsion composition.