JP5587295B2 - イオン交換特性を有する官能化基材 - Google Patents
イオン交換特性を有する官能化基材 Download PDFInfo
- Publication number
- JP5587295B2 JP5587295B2 JP2011508544A JP2011508544A JP5587295B2 JP 5587295 B2 JP5587295 B2 JP 5587295B2 JP 2011508544 A JP2011508544 A JP 2011508544A JP 2011508544 A JP2011508544 A JP 2011508544A JP 5587295 B2 JP5587295 B2 JP 5587295B2
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3847—Multimodal interactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28095—Shape or type of pores, voids, channels, ducts
- B01J20/28097—Shape or type of pores, voids, channels, ducts being coated, filled or plugged with specific compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3221—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond the chemical bond being an ionic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3285—Coating or impregnation layers comprising different type of functional groups or interactions, e.g. different ligands in various parts of the sorbent, mixed mode, dual zone, bimodal, multimodal, ionic or hydrophobic, cationic or anionic, hydrophilic or hydrophobic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3295—Coatings made of particles, nanoparticles, fibers, nanofibers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J43/00—Amphoteric ion-exchange, i.e. using ion-exchangers having cationic and anionic groups; Use of material as amphoteric ion-exchangers; Treatment of material for improving their amphoteric ion-exchange properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/118,447 | 2008-05-09 | ||
| US12/118,447 US9314712B2 (en) | 2008-05-09 | 2008-05-09 | Functionalized substrates with ion-exchange properties |
| PCT/US2009/041563 WO2009137275A1 (en) | 2008-05-09 | 2009-04-23 | Functionalized substrates with ion-exchange properties |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011523041A JP2011523041A (ja) | 2011-08-04 |
| JP2011523041A5 JP2011523041A5 (enExample) | 2012-06-14 |
| JP5587295B2 true JP5587295B2 (ja) | 2014-09-10 |
Family
ID=41119796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011508544A Active JP5587295B2 (ja) | 2008-05-09 | 2009-04-23 | イオン交換特性を有する官能化基材 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9314712B2 (enExample) |
| EP (1) | EP2279034B1 (enExample) |
| JP (1) | JP5587295B2 (enExample) |
| WO (1) | WO2009137275A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11439977B2 (en) | 2009-06-01 | 2022-09-13 | Waters Technologies Corporation | Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material |
| EP2437882A4 (en) | 2009-06-01 | 2016-11-23 | Waters Technologies Corp | HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS |
| EP4023330A1 (en) * | 2009-12-15 | 2022-07-06 | Waters Technologies Corporation | Device and methods for performing size exclusion chromatography |
| WO2012018598A1 (en) | 2010-07-26 | 2012-02-09 | Waters Technologies Corporation | Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations |
| US9136516B2 (en) * | 2010-12-29 | 2015-09-15 | Industrial Technology Research Institute | Hybrid materials using ionic particles |
| RU2499628C2 (ru) * | 2012-02-28 | 2013-11-27 | Федеральное государственное бюджетное учреждение науки Ордена Ленина и Ордена Октябрьской революции Институт геохимии и аналитической химии им. В.И. Вернадского Российской академии наук (ГЕОХИ РАН) | Способ приготовления высокоэффективных колонок для ионной хроматографии |
| BR112015005937A2 (pt) | 2012-09-17 | 2017-07-04 | Grace W R & Co | meios e dispositivos cromatográficos |
| US9310344B2 (en) | 2013-06-14 | 2016-04-12 | Dionex Corporation | HILIC/anion-exchange/cation-exchange multimodal media |
| EP2745904B1 (en) * | 2012-12-21 | 2015-12-16 | Dionex Corporation | HILIC/Anion-Exchange/Cation-Exchange Multimodal Media |
| US9169331B2 (en) | 2012-12-21 | 2015-10-27 | Dionex Corporation | Separation of glycans by mixed-mode liquid chromatography |
| US9329158B2 (en) | 2013-03-15 | 2016-05-03 | Dionex Corporation | Epoxy chemistry derived materials as mixed mode chromatography media, method for their synthesis and use |
| US11389783B2 (en) | 2014-05-02 | 2022-07-19 | W.R. Grace & Co.-Conn. | Functionalized support material and methods of making and using functionalized support material |
| US9340562B1 (en) * | 2014-10-29 | 2016-05-17 | Thermo Electron Manufacturing Limited | Chromatographic material and method for preparation thereof |
| US11002691B2 (en) * | 2014-12-31 | 2021-05-11 | Graham F. Peaslee | Method for detecting fluorinated chemicals in liquid |
| PL3302784T3 (pl) | 2015-06-05 | 2022-01-17 | W.R. Grace & Co.-Conn. | Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania |
| JP6705189B2 (ja) * | 2016-02-02 | 2020-06-03 | 日立化成株式会社 | 分離材及びカラム |
| US20190015815A1 (en) | 2016-03-06 | 2019-01-17 | Waters Technologies Corporation | Superficially porous materials comprising a coated core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations |
| US10618920B2 (en) | 2016-06-03 | 2020-04-14 | Agilent Technologies, Inc. | Functionalized particles having modified phases |
| US12134089B2 (en) | 2017-01-20 | 2024-11-05 | Dionex Corporation | Multimodal chromatographic media for protein separation |
| US20200261887A1 (en) * | 2017-07-25 | 2020-08-20 | University Of South Australia | Improvements in Solid Phase Micro-Extraction Substrate Coatings |
| JP2021532089A (ja) * | 2018-07-13 | 2021-11-25 | ウィルマー トレーディング ピーティーイー リミテッド | 有機シラン化合物およびその製造方法および使用方法 |
| US12485364B2 (en) | 2018-08-10 | 2025-12-02 | Clemson University Research Foundation | Multi-modal ion-exchange membranes for rapid separations |
| WO2020123714A1 (en) | 2018-12-12 | 2020-06-18 | Purilogics, LLC | Affinity membrane and method of preparation |
| US11198117B2 (en) * | 2019-11-04 | 2021-12-14 | Dionex Corporation | Longitudinal gradient chromatography columns |
| EP4090457B1 (en) * | 2020-01-16 | 2025-04-23 | FUJIFILM Electronic Materials U.S.A, Inc. | Systems and methods for purifying solvents |
| CN112755985B (zh) * | 2020-12-28 | 2023-08-25 | 纳谱分析技术(苏州)有限公司 | 一种液相色谱分离介质及其制备方法和应用 |
| CN113687005B (zh) * | 2021-09-17 | 2023-07-14 | 海南葫芦娃药业集团股份有限公司 | 小儿肺热咳喘颗粒中盐酸麻黄碱与盐酸伪麻黄碱的含量测定方法 |
| CN114699799B (zh) * | 2022-03-03 | 2023-06-23 | 江苏汉德科技有限公司 | 一种具有离子交换特征的氨基甲酸酯色谱填料的制备方法 |
| US20240218137A1 (en) * | 2022-12-28 | 2024-07-04 | Dionex Corporation | Latex hyperbranched anion exchangers |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4382124B1 (en) | 1958-07-18 | 1994-10-04 | Rohm & Haas | Process for preparing macroreticular resins, copolymers and products of said process |
| US3926559A (en) * | 1973-08-06 | 1975-12-16 | Dow Chemical Co | Method and apparatus for quantitative chromatographic analysis of cationic species |
| US4314823A (en) * | 1979-03-05 | 1982-02-09 | Dionex Corporation | Combination apparatus and method for chromatographic separation and quantitative analysis of multiple ionic species |
| US4252644A (en) * | 1979-05-25 | 1981-02-24 | The Dow Chemical Company | High performance ion exchange composition and the removal and separation of ions therewith |
| US4351909A (en) * | 1979-10-01 | 1982-09-28 | The Dow Chemical Co. | High performance ion-exchange composition |
| US4383047A (en) | 1981-02-17 | 1983-05-10 | The Dow Chemical Company | High performance anion-exchange chromatographic packing composition |
| US4519905A (en) | 1981-02-17 | 1985-05-28 | The Dow Chemical Company | High performance analytical column for anion determination |
| US4376047A (en) | 1981-06-18 | 1983-03-08 | Dionex Corporation | Coated resin ion exchange composition |
| US4927539A (en) * | 1983-05-02 | 1990-05-22 | The Dow Chemical Company | High performance anion-exchange chromatographic packing composition consisting of low porosity synthetic resin gel particle substrate coated with liquid water-soluble aminated resin |
| US4455233A (en) * | 1983-08-12 | 1984-06-19 | Dionex Corporation | Method and apparatus for ion analysis and detection using reverse mode suppression |
| US5110784A (en) * | 1984-04-09 | 1992-05-05 | Dow Corning Corporation | Dual surface porous material |
| US4782040A (en) * | 1984-04-09 | 1988-11-01 | Dow Corning Corporation | Porous materials having a dual surface |
| US4874520A (en) * | 1986-04-23 | 1989-10-17 | Battelle Development Corporation | Chromatographic process |
| CA1331254C (en) | 1989-02-27 | 1994-08-02 | Victor Berber Barretto | Ion-exchange composition employing resin attachment to dispersant and method for forming the same |
| SE8902315D0 (sv) * | 1989-06-27 | 1989-06-27 | Pharmacia Ab | Anjonbytare |
| US5328603A (en) * | 1990-03-20 | 1994-07-12 | The Center For Innovative Technology | Lignocellulosic and cellulosic beads for use in affinity and immunoaffinity chromatography of high molecular weight proteins |
| US5532279A (en) | 1990-05-03 | 1996-07-02 | Dionex Corporation | Ion-exchange composition employing resin attachment to dispersant and method for forming the same |
| US5130343A (en) | 1991-03-13 | 1992-07-14 | Cornell Research Foundation, Inc. | Process for producing uniform macroporous polymer beads |
| DE4130475A1 (de) * | 1991-09-13 | 1993-03-18 | Merck Patent Gmbh | Modifizierte chromatographische traegermaterialien |
| US5260094A (en) | 1991-09-30 | 1993-11-09 | Cornell Research Foundation, Inc. | Preparing densified low porosity titania sol-gel forms |
| DE69211010T2 (de) | 1991-10-21 | 1997-01-23 | Cornell Res Foundation Inc | Chromographiesäule mit makroporöser Polymerfüllung |
| US5512169A (en) * | 1992-12-30 | 1996-04-30 | Dow Corning Corporation | Liquid column packing materials |
| US5728457A (en) | 1994-09-30 | 1998-03-17 | Cornell Research Foundation, Inc. | Porous polymeric material with gradients |
| SE9504205D0 (sv) * | 1995-11-24 | 1995-11-24 | Pharmacia Biotech Ab | A chromatographic separation method and device |
| EP0883574B1 (en) | 1996-03-01 | 2004-01-02 | Dionex Corporation | Anion-exchange resins with at least two different nitrogen containing ion-exchange groups |
| US5929214A (en) | 1997-02-28 | 1999-07-27 | Cornell Research Foundation, Inc. | Thermally responsive polymer monoliths |
| US5936003A (en) | 1997-03-03 | 1999-08-10 | Dionex Corporation | Hydrolytically stable resins for use in anion-exchange chromatography |
| US5865994A (en) | 1997-03-13 | 1999-02-02 | Dionex Corporation | Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography |
| WO1999012624A1 (en) | 1997-09-08 | 1999-03-18 | Dionex Corporation | Bifunctional resin composition for the simultaneous separation of carbohydrates and organic acids in liquid chromatography |
| US6881761B2 (en) * | 2000-05-29 | 2005-04-19 | Showa Denko K.K. | Porous polymer particle, anion exchanger, producing method thereof, column for ion chromatography, and method for measuring anions |
| JP2002210377A (ja) * | 2001-01-22 | 2002-07-30 | Tosoh Corp | アニオン交換体、その製造方法及びそれを用いた用途 |
| US6528167B2 (en) | 2001-01-31 | 2003-03-04 | Waters Investments Limited | Porous hybrid particles with organic groups removed from the surface |
| US20030077656A1 (en) | 2001-09-07 | 2003-04-24 | Bordunov Andrei V. | Derivatized macrocycle compound for covalent bonding to a substrate and method of forming and use |
| US6887384B1 (en) | 2001-09-21 | 2005-05-03 | The Regents Of The University Of California | Monolithic microfluidic concentrators and mixers |
| US6749749B2 (en) | 2002-06-26 | 2004-06-15 | Isco, Inc. | Separation system, components of a separation system and methods of making and using them |
| US20040018559A1 (en) * | 2002-07-26 | 2004-01-29 | Applera Corporation | Size-exclusion ion-exchange particles |
| SE0202551D0 (sv) * | 2002-08-27 | 2002-08-27 | Amersham Biosciences Ab | Chromatographic two-layer particles |
| US7045059B2 (en) | 2003-07-28 | 2006-05-16 | Sielc Technologies Corp | Universal bonded phase material for chromatographic separation |
| US7074491B2 (en) | 2003-11-04 | 2006-07-11 | Dionex Corporation | Polar silanes for binding to substrates and use of the bound substrates |
| US7303671B2 (en) | 2004-02-11 | 2007-12-04 | Dionex Corporation | Ion exchange particle-bound flow-through porous monolith |
| US7402243B2 (en) | 2004-09-10 | 2008-07-22 | Dionex Corporation | Organosilanes and substrate bonded with same |
| US7563367B2 (en) | 2004-10-01 | 2009-07-21 | Phenomenex, Inc. | pH stable chromatographic media using templated multilayer organic/inorganic grafting |
| EP1693108A1 (en) * | 2004-12-04 | 2006-08-23 | MERCK PATENT GmbH | Mixed-modal anion-exchange type separation material |
| US7468130B2 (en) | 2005-02-15 | 2008-12-23 | Dionex Corporation | Organosilanes and substrates covalently bonded with same and methods for synthesis and use same |
| US9283494B2 (en) * | 2005-09-16 | 2016-03-15 | Dionex Corporation | Agglomerated ion exchange particle bed and method |
-
2008
- 2008-05-09 US US12/118,447 patent/US9314712B2/en active Active
-
2009
- 2009-04-23 EP EP09743262.9A patent/EP2279034B1/en active Active
- 2009-04-23 JP JP2011508544A patent/JP5587295B2/ja active Active
- 2009-04-23 WO PCT/US2009/041563 patent/WO2009137275A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009137275A1 (en) | 2009-11-12 |
| EP2279034A1 (en) | 2011-02-02 |
| US20090277838A1 (en) | 2009-11-12 |
| JP2011523041A (ja) | 2011-08-04 |
| EP2279034B1 (en) | 2019-05-22 |
| US9314712B2 (en) | 2016-04-19 |
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