JP5417425B2 - Magnetic resonance diagnostic equipment - Google Patents

Description

  The present invention relates to a magnetic resonance diagnostic apparatus that performs magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS).

  This type of apparatus is known from, for example, Japanese Patent Application Laid-Open No. H10-228707.

  In this type of apparatus, the user can designate a region (hereinafter referred to as an imaging region) where magnetic resonance signals for MRS are collected with reference to an image captured by MRI (hereinafter referred to as an MRI image). It is like that. Incidentally, in recent years, there has been a growing demand for three-dimensional spectroscopy collection (3DMRS collection) using multi-slices. When performing this 3DMRS collection, a large number of voxels are three-dimensionally arranged in the imaging region. In general, the user can confirm the position of each voxel by superimposing and displaying a line representing the outer shape of the voxel on the MRI image.

  Further, in the above apparatus, the user can designate an area (hereinafter referred to as a measurement area) where the spectrum of the collected magnetic resonance signal is measured with reference to the MRI image.

JP 2001-187038 A

  Since the measurement area can be specified regardless of the imaging area or the voxel, it is difficult to specify the measurement area as such even when the user wants to set a specific voxel as the MR measurement area. Met.

  An object of the present invention is to provide a magnetic resonance diagnostic apparatus that allows a user to easily specify an imaging region or a measurement region associated with a voxel.

  In order to achieve the above object, the present invention provides an imaging region determination means for determining an imaging region on a positioning image in a magnetic resonance diagnostic apparatus for measuring a magnetic resonance spectrum for a plurality of voxels defined in the imaging region. A measurement area determining means for determining a measurement area for measuring the magnetic resonance spectrum on the positioning image; and before the change to the measurement area is made in response to the imaging area determining means changing the imaging area. Change determining means for changing and determining the measurement region so as to maintain a relative positional relationship with the imaging region.

  In order to achieve the above object, the present invention provides an imaging region determination means for determining an imaging region on a positioning image in a magnetic resonance diagnostic apparatus for measuring a magnetic resonance spectrum for a plurality of voxels defined in the imaging region. A measurement area determining means for determining a measurement area for measuring the magnetic resonance spectrum on the positioning image; and before the change to the imaging area in response to the measurement area determining means changing the measurement area. Change determination means for changing and determining the imaging region so as to maintain a relative positional relationship with the measurement region.

  According to the present invention, it is possible to provide a magnetic resonance diagnostic apparatus that allows a user to easily specify a measurement region associated with an imaging region or a voxel.

The figure which shows the structure of the magnetic resonance diagnostic apparatus which concerns on one Embodiment of this invention. The flowchart which shows the process sequence of the control part 17 in FIG. 1 regarding the setting of an imaging region and ROI. The figure which shows the example of a display of an imaging area line and a grid line. The figure which shows the example of a display of an imaging area line and a grid line. The flowchart which shows the process sequence of the control part 17 in FIG. 1 in a ROI setting process. The figure which shows an example of the designation | designated condition by the user of ROI. The figure which shows an example of ROI set based on the designation | designated condition shown in FIG. The flowchart which shows the process sequence of the control part 17 in FIG. 1 in an imaging area change process. The figure which shows an example of the setting state of the imaging area which an oblique generate | occur | produces. The figure which shows the example of a display in the image for positioning which is oblique with respect to the imaging region.

  Hereinafter, an embodiment of the present invention will be described with reference to the drawings.

  FIG. 1 is a diagram showing a configuration of a magnetic resonance diagnostic apparatus according to the present embodiment. The magnetic resonance diagnostic apparatus shown in FIG. 1 includes a static magnetic field magnet 1, a gradient magnetic field coil 2, a gradient magnetic field power source 3, a bed 4, a bed control unit 5, RF coil units 6a, 6b, 6c, a transmission unit 7, and a selection circuit 8. A receiving unit 9 and a computer system 10.

  The static magnetic field magnet 1 has a hollow cylindrical shape and generates a uniform static magnetic field in an internal space. As the static magnetic field magnet 1, for example, a permanent magnet, a superconducting magnet or the like is used.

  The gradient magnetic field coil 2 has a hollow cylindrical shape and is disposed inside the static magnetic field magnet 1. The gradient magnetic field coil 2 is a combination of three types of coils corresponding to the X, Y, and Z axes orthogonal to each other. The gradient magnetic field coil 2 generates a gradient magnetic field in which the above three types of coils are individually supplied with current from the gradient magnetic field power supply 3 and the magnetic field strength is inclined along the X, Y, and Z axes. The Z-axis direction is, for example, the same direction as the static magnetic field. The gradient magnetic fields of the X, Y, and Z axes correspond to, for example, the slice selection gradient magnetic field Gs, the phase encoding gradient magnetic field Ge, and the readout gradient magnetic field Gr, respectively. The slice selection gradient magnetic field Gs is used to arbitrarily determine an imaging section. The phase encoding gradient magnetic field Ge is used to change the phase of the magnetic resonance signal in accordance with the spatial position. The readout gradient magnetic field Gr is used for changing the frequency of the magnetic resonance signal in accordance with the spatial position.

  The subject P is inserted into the cavity (imaging port) of the gradient coil 2 while being placed on the top 4 a of the bed 4. The couch 4 is driven by the couch controller 5 and moves the top plate 4a in the longitudinal direction (left-right direction in FIG. 1) and up-down direction. Usually, the bed 4 is installed such that the longitudinal direction thereof is parallel to the central axis of the static magnetic field magnet 1.

  The RF coil unit 6a is configured by housing one or more coils in a cylindrical case. The RF coil unit 6 a is disposed inside the gradient magnetic field coil 2. The RF coil unit 6a receives a high frequency pulse (RF pulse) from the transmitter 7 and generates a high frequency magnetic field.

  The RF coil units 6b and 6c are placed on the top 4a, built in the top 4a, or attached to the subject P. And at the time of imaging | photography, it inserts in the cavity of the gradient coil 2 with the subject P. Array coils are used as the RF coil units 6b and 6c. That is, each of the RF coil units 6b and 6c includes a plurality of element coils. The element coils provided in the RF coil units 6b and 6c each receive a magnetic resonance signal radiated from the subject P. The output signals of the element coils are individually input to the selection circuit 8. The receiving RF coil unit is not limited to the RF coil units 6b and 6c, and various types of RF coil units can be arbitrarily attached. One or three or more RF coil units for reception may be attached.

  The transmission unit 7 includes an oscillation unit, a phase selection unit, a frequency conversion unit, an amplitude modulation unit, and a high frequency power amplification unit. The oscillation unit generates a high-frequency signal having a resonance frequency unique to the target nucleus in the static magnetic field. The phase selection unit selects the phase of the high-frequency signal. The frequency conversion unit converts the frequency of the high-frequency signal output from the phase selection unit. The amplitude modulation unit modulates the amplitude of the high-frequency signal output from the frequency modulation unit, for example, according to a sync function. The high frequency power amplification unit amplifies the high frequency signal output from the amplitude modulation unit. As a result of the operation of each of these units, the transmission unit 7 supplies an RF pulse corresponding to the Larmor frequency to the RF coil unit 6a.

  The selection circuit 8 selects some of a number of magnetic resonance signals output from the RF coil units 6b and 6c. Then, the selection circuit 8 gives the selected magnetic resonance signal to the reception unit 9. Which channel is selected is instructed from the computer system 10.

  The receiving unit 9 includes a plurality of processing systems including a pre-stage amplifier, a phase detector, and an analog / digital converter. Magnetic resonance signals selected by the selection circuit 8 are respectively input to the processing systems of these multiple channels. The pre-stage amplifier amplifies the magnetic resonance signal. The phase detector detects the phase of the magnetic resonance signal output from the preamplifier. The analog-digital converter converts the signal output from the phase detector into a digital signal. The receiving unit 9 outputs a digital signal obtained by each processing system.

  The computer system 10 includes an interface unit 11, a data collection unit 12, a reconstruction unit 13, a storage unit 14, a display unit 15, an input unit 16, and a control unit 17.

  The interface unit 11 is connected to the gradient magnetic field power source 3, the bed control unit 5, the transmission unit 7, the reception unit 9, the selection circuit 8, and the like. The interface unit 11 inputs and outputs signals exchanged between these connected units and the computer system 10.

  The data collection unit 12 collects digital signals output from the reception unit 9. The data collection unit 12 stores the collected digital signal, that is, magnetic resonance signal data in the storage unit 14.

  The reconstruction unit 13 performs post-processing, that is, reconstruction such as Fourier transform, on the magnetic resonance signal data stored in the storage unit 14, and obtains spectrum data or image data of the desired nuclear spin in the subject P. Ask.

  The storage unit 14 stores magnetic resonance signal data and spectrum data or image data for each patient.

  The display unit 15 displays various information such as spectrum data or image data under the control of the control unit 17. As the display unit 15, a display device such as a liquid crystal display can be used.

  The input unit 16 receives various commands and information input from the operator. As the input unit 16, a pointing device such as a mouse or a trackball, a selection device such as a mode change switch, or an input device such as a keyboard can be used as appropriate.

  The control unit 17 includes a CPU, a memory, and the like, and comprehensively controls the magnetic resonance diagnostic apparatus of the present embodiment. The control unit 17 has several functions as follows. One of the functions determines an imaging region on a positioning image reconstructed by MRI. One of the functions is to display an imaging region image representing an imaging region and voxels in the imaging region so as to be superimposed on the positioning image. One of the functions determines an ROI representing a measurement region on the positioning image. One of the functions is to change and determine the ROI so as to maintain the relative positional relationship between the ROI and the imaging area before being changed in response to the change of the imaging area. One of the functions is to change and determine the imaging region so as to maintain the relative positional relationship between the imaging region and the ROI before being changed in response to the ROI being changed and determined.

  Next, the operation of the magnetic resonance diagnostic apparatus configured as described above will be described.

  FIG. 2 is a flowchart showing a processing procedure of the control unit 17 related to the setting of the imaging region and the ROI.

  In step Sa1, the control unit 17 displays the positioning image on the display unit 15. The positioning image is an MRI image acquired in advance by a known method. In order to easily determine the three-dimensional imaging region and the ROI, it is desirable to use at least two of the sagittal image, the axial image, and the coronal image as positioning images. In the present embodiment, an axial image and a coronal image are used as positioning images.

  In step Sa2, the control unit 17 inputs a voxel condition specified by the user using the input unit 16. The voxel condition is a condition for determining a voxel and includes, for example, information on the position and size of the imaging region and the size of the voxel. The position and size of the imaging region are input by inputting a rectangular designation on each positioning image representing, for example, an axial image and a coronal image. In step Sa3, the control unit 17 determines a voxel and an imaging region. For example, the control unit 17 determines a rectangular parallelepiped region having two designated rectangles as two orthogonal surfaces as an imaging region. Further, the control unit 17 determines the position of the voxel by arranging voxels having a designated size in the imaging region.

  In step Sa4, the control unit 17 superimposes and displays an imaging area line representing the outer shape of the imaging area and a grid line representing the voxel boundary on the positioning image. 3 and 4 are diagrams showing display examples of imaging area lines and grid lines. In FIG. 3, the imaging area line 22 and the grid line 23 are superimposed and displayed on the positioning image 21 representing the axial image. In FIG. 4, the imaging area line 32 and the grid line 33 are superimposed and displayed on the positioning image 31 representing the coronal image.

  In steps Sa5 to Sa7, the control unit 17 waits for an ROI setting instruction, a change instruction, or a completion instruction.

  If the user gives an instruction to start setting the ROI, the control unit 17 proceeds from step Sa5 to step Sa8. In step Sa8, the control unit 17 executes ROI setting processing.

  FIG. 5 is a flowchart showing a processing procedure of the control unit 17 in the ROI setting process.

  In step Sb1, the control unit 17 confirms whether a new ROI setting is requested. If a new ROI setting is requested, the control unit 17 proceeds from step Sb1 to step Sb2. In step Sb2, the control unit 17 determines an area designated by the user as the ROI. The designation of the region here is performed by designation of a rectangle on each of the positioning images representing the axial image and the coronal image, for example. The control unit 17 determines a rectangular parallelepiped region having the two specified rectangles as two orthogonal surfaces as the specified region.

  In step Sb3, the control unit 17 fits the determined area to the voxel boundary. In step Sb4, the control unit 17 determines the designated area after fitting as the ROI.

  Specifically, when a rectangle 41 as shown in FIG. 6 is designated on the axial plane, the rectangle 42 shown in FIG. 7 fitted to the voxel boundary (that is, grid line) is used as one surface, and the coronal As for the surface, a rectangular parallelepiped region having a rectangle defined in the same manner as one surface is determined as the ROI.

  When the change of the ROI that has already been determined as described above is requested, the control unit 17 proceeds from step Sb1 to step Sb5. In step Sb5, the control unit 17 changes the ROI according to a user instruction.

  In step Sb6, the controller 17 checks whether or not the fixed mode is set. The fixed mode is set / released according to a user instruction. If the fixed mode is set, the control unit 17 proceeds from step Sb6 to step Sb7. In step Sb7, the control unit 17 changes the imaging region so as to maintain the relative positional relationship between the ROI before the change and the imaging region. However, if the fixed mode is not set, the control unit 17 proceeds from step Sb6 to step Sb8. In step Sb8, the control unit 17 further fits the changed ROI to the voxel boundary.

  If step Sb4, step Sb7, or step Sb8 is completed, the control unit 17 ends the ROI setting process. Then, the control unit 17 returns to the standby state of steps Sa5 to Sa7 shown in FIG.

  If the user gives an instruction to start changing the imaging area in the standby state of steps Sa5 to Sa7, the control unit 17 proceeds from step Sa6 to step Sa9. In step Sa9, the control unit 17 executes an imaging area changing process.

  FIG. 8 is a flowchart showing a processing procedure of the control unit 17 in the imaging area changing process.

  In step Sc1, the control unit 17 changes the imaging region in accordance with a user instruction.

  In step Sc2, the control unit 17 confirms whether or not there is an ROI in the imaging region. If there is an ROI, the control unit 17 proceeds from step Sc2 to step Sc3.

  In step Sc3, the control unit 17 checks whether or not the fixed mode is set. If the fixed mode is set, the control unit 17 proceeds from step Sc3 to step Sc4. In step Sc4, the control unit 17 changes the ROI so as to maintain the relative positional relationship between the imaging region before the change and the ROI. However, if the fixed mode is not set, the control unit 17 proceeds from step Sc3 to step Sc5. In step Sc5, the control unit 17 fits the ROI to the boundary of voxels included in the changed imaging region.

  If step Sc4 or step Sc5 is completed, or if it is confirmed in step Sc2 that there is no ROI, the control unit 17 ends the imaging region changing process. Then, the control unit 17 proceeds to step Sa10 shown in FIG.

  In step Sa10, the control unit 17 confirms whether or not the imaging region after being changed by the imaging region changing process is oblique to the positioning image. Here, “oblique” refers to a state in which the slice direction of the positioning image and the slice direction in the imaging region are not parallel or vertical. If there is no such leak, the control unit 17 proceeds from step Sa10 to step Sa11. In step Sa11, the control unit 17 superimposes and displays an imaging area line representing the outer shape of the imaging area after the change and a grid line representing the boundary of the changed voxel on the positioning image. Thereafter, the control unit 17 returns to the standby state of steps Sa5 to Sa7.

  On the other hand, for example, as shown in FIG. 9, when the imaging area is tilted on the axial plane, the slice plane in the imaging area is not horizontal or perpendicular to the coronal plane. In such a case, the control unit 17 proceeds from step Sa10 to step Sa12. In step Sa12, the control unit 17 superimposes and displays only the imaging area line representing the imaging area with respect to the positioning image that is oblique to the imaging area. In the case of the above example, the imaging region line 34 is superimposed and displayed with respect to the positioning image 31 representing the coronal image as shown in FIG. This imaging area line 34 represents the boundary of the slice of the axial plane in addition to the outer shape of the imaging area. That is, the imaging area line 34 represents an imaging area by so-called slice display. The imaging area line 34 may be changed to a so-called whole display or center line display that represents the imaging area. The entire display represents only the outer shape of the imaging area. The center line display represents only the center plane of the slice. Thereafter, the control unit 17 returns to the standby state of steps Sa5 to Sa7.

  If the completion instruction is given by the user in the standby state of steps Sa5 to Sa7, the control unit 17 exits this standby state from step Sa7 and ends the processing.

  As described above, according to the present embodiment, when the slice plane in the imaging region is not oblique to the positioning image, the grid line representing the voxel boundary is displayed in addition to the imaging region line representing the imaging region. Although superimposed on the positioning image, if it is oblique, only the imaging area line is superimposed and the grid line is not displayed, so that the display is very easy to see.

  Further, according to the present embodiment, when the imaging area or ROI is changed, the ROI or imaging area is also automatically changed so as to maintain the relative positional relationship, so the user changes the imaging area or ROI. Accordingly, it is not necessary to perform an operation for changing the ROI or the imaging region, and the burden on the user is reduced. That is, the imaging area and the ROI can be changed in conjunction with each other.

  Further, according to the present embodiment, when the imaging region or ROI is changed, the ROI is fitted to the voxel with the changed relative positional relationship, so even when the imaging region or ROI is changed independently. After the change, the ROI can be matched with the position of the voxel in the imaging region. Therefore, the user can change the imaging area or ROI without being aware of the detailed positional relationship between the imaging area and the ROI.

  In addition, according to the present embodiment, the user can arbitrarily change the imaging area and ROI interlocking change and the imaging area or ROI independent change according to the setting of the fixed mode. Is possible and convenient.

  Note that the present invention is not limited to the above-described embodiment as it is, and can be embodied by modifying the constituent elements without departing from the scope of the invention in the implementation stage. In addition, various inventions can be formed by appropriately combining a plurality of components disclosed in the embodiment. For example, some components may be deleted from all the components shown in the embodiment.

  DESCRIPTION OF SYMBOLS 1 ... Static magnetic field magnet, 2 ... Gradient magnetic field coil, 3 ... Gradient magnetic field power supply, 4 ... Bed, 5 ... Bed control part, 6a, 6b, 6c ... RF coil unit, 7 ... Transmission part, 8 ... Selection circuit, 9 ... Receiving unit, 10 computer system, 11 interface unit, 12 data collection unit, 13 reconstruction unit, 14 storage unit, 15 display unit, 16 input unit, 17 control unit.

Claims (4)

In a magnetic resonance diagnostic apparatus for measuring a magnetic resonance spectrum for a voxel having a plurality defined in an imaging region,
An imaging area determining means for determining the imaging area on the positioning image;
Measurement region determining means for determining a measurement region for measuring the magnetic resonance spectrum on the positioning image;
Change determination for determining and changing the measurement area so as to maintain the relative positional relationship between the measurement area and the imaging area before being changed in response to the imaging area determination unit changing and determining the imaging area And a magnetic resonance diagnostic apparatus.   The magnetic resonance diagnostic apparatus according to claim 1, wherein the change determination unit changes and determines the measurement region when a specific mode is set. In a magnetic resonance diagnostic apparatus for measuring a magnetic resonance spectrum for a voxel having a plurality defined in an imaging region,
An imaging area determining means for determining the imaging area on the positioning image;
Measurement region determining means for determining a measurement region for measuring the magnetic resonance spectrum on the positioning image;
Change determination for changing and determining the imaging area so as to maintain the relative positional relationship between the imaging area and the measurement area before being changed in response to the measurement area determining means changing and determining the measurement area And a magnetic resonance diagnostic apparatus.   The magnetic resonance diagnostic apparatus according to claim 3, wherein the change determination unit changes and determines the imaging region when a specific mode is set.

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