JP5307362B2 - Transparent gel composition and transparent gel preparation method - Google Patents

Description

  The present invention relates to a transparent gel-like composition, and in particular, relates to a transparent gel-like composition capable of forming a gel having excellent transparency.

  Conventionally, a gel-like fragrance or a gel-like deodorant in which a fragrance or a deodorant component is dispersed or solubilized in water and gelled with a gelling agent has been proposed. As a gelling agent used for these gel-like fragrances and the like, agar, carrageenan, gelatin, gellan gum and the like are known.

  In such gel-like fragrances and gel-like deodorants, in order to appeal their aesthetics and cleanliness, a highly transparent one is desired, but a gelling agent that can form a highly transparent gel. The current situation is limited. For example, Patent Documents 1 to 3 disclose that a highly transparent gel is formed using carrageenan as a gelling agent. However, in reality, these materials are not sufficiently transparent. I couldn't.

  Further, Patent Document 4 discloses a transparent gel composition containing gellan gum, a volatile agent and a surfactant. However, gels using gellan gum tend to cause water separation, and the formed gel is hard. And had the problem of being brittle.

For this reason, transparent gels using gelatin are currently used. However, gelatin has a problem of forming a film with the evaporation of fragrances and fragrance components, and when bacteria with proteases propagate, There was a risk of breaking the structure and melting the gel.
JP-A-62-41661 JP-A 63-43666 Japanese Unexamined Patent Publication No. 63-260956 JP-A-1-74239

  Therefore, it has been desired to provide a transparent gel-like composition that has high transparency, does not cause water separation, and is unlikely to cause problems such as film formation and gel destruction due to bacterial growth.

  The present inventors paid attention to carrageenan as a gelling agent and conducted research to increase its transparency. And, as the cause of low transparency of carrageenan, it was considered that the remaining of protein, calcium salt, crude fiber, and pigment were caused by each or synergistically, and the relationship between these impurities and transparency was examined. It has been found that the above-mentioned impurities have a relationship with transparency, and the transparency problem of the gel composition can be solved by making the content of impurities in the carrageenan less than a certain level, and the present invention has been completed.

  That is, the present invention is a transparent gel composition containing a gelling agent, a volatilizing agent, a surfactant and water, and the nitrogen content in the dried product as a gelling agent is 0.01% by mass or less, 100 g A transparent gel-like composition characterized by containing purified κ-carrageenan having a per calcium content of 25 mg or less.

The present invention also provides a purified κ-carrageenan having a nitrogen content of 0.01% by mass or less and a calcium content per 100 g of 25 mg or less as a gelling agent in water heated to 80 ° C. or more. A transparent gel characterized in that a dispersion in which a volatile agent is dispersed is added, a solution in which a volatile drug is previously dissolved or dispersed is added and mixed, and then the mixture is filled in a container and cooled. It is a manufacturing method of a state medicine.

  The gel composition of the present invention is an aqueous gel that has high transparency and does not cause water separation. Moreover, this gel is rich in elasticity and can maintain transparency until the end of volatilization.

  In the present specification, the nitrogen content of carrageenan and the calcium content per 100 g mean values measured with a dried product obtained by removing moisture contained in carrageenan by heating at 90 ° C. for 1 hour in a dryer. In the case of κ-carrageenan, the purified carrageenan used in the production of the gel composition of the present invention has a dry matter nitrogen content of 0.01% by mass or less and a calcium content per 100 g of 25 mg or less (hereinafter referred to as “carried product”). In the case of iota-carrageenan, the nitrogen content of the dried product is 0.04% by mass or less and the calcium content per 100 g is 35 mg or less (hereinafter referred to as “ Refined ι-carrageenan ”).

  The nitrogen content in carrageenan indicates the amount of protein contained in carrageenan, and this value can be calculated from the nitrogen content obtained by a conventionally known method, for example, Kjeldahl method. Further, the calcium content in carrageenan can also be determined by a conventionally known measurement method, for example, ICP emission analysis.

  The purified carrageenan having the nitrogen content and calcium content as described above is purified by a method combining raw carrageenans with various known purification methods so that the nitrogen content and calcium content are finally obtained. As an example of a preferable method, the following method can be given.

  That is, the red algae raw algae that are the raw materials for carrageenan are washed with water and boiled in an alkaline inorganic salt aqueous solution or hot water to extract carrageenan. Examples of the alkali inorganic salt used in this step include potassium hydroxide and sodium hydroxide, and the concentration is preferably about 5 to 15% by mass (hereinafter simply referred to as “%”).

  Next, a filter aid is added to the obtained aqueous extraction solution, and this is filtered through a filter while applying a pressure of about 0.5 to 10 bar, preferably about 1 to 6 bar, to obtain a carrageenan aqueous solution. As the filter aid used here, conventionally known perlite, diatomaceous earth, activated carbon and the like can be used. Further, the filter may be precoated with a filter aid, or the filter agent may be body-fed into an aqueous solution.

  Further, the carrageenan aqueous solution obtained by filtration is concentrated with an ultrafilter, and the resulting concentrated liquid is ejected into an aqueous alcohol solution such as isopropanol of 70% or more to precipitate the carrageenan, which is separated and dried to obtain a purified carrageenan. be able to. Examples of the ultrafilter used here include an ultrafilter (manufactured by Advanced Membrane Technology). In addition, it is preferable to stir the alcohol aqueous solution when the concentrate is ejected into a 70% or more alcohol aqueous solution.

  In producing the transparent gel composition of the present invention, it is preferable to use at least purified κ-carrageenan as a gelling agent. This purified kappa-carrageenan uses, for example, the original algae of C. crispus of the E. cottonii of the Solieriaceae genus (Eucheuma) or the genus Gigitinaceae (Chondrus) as the red algae raw material. It can be obtained by manufacturing according to the method.

  In addition, as a transparent gel-like composition, it does not flow, has gelatin-like elasticity, little water separation, gel shrinkage, and a gel with a clear end point, to obtain purified κ-carrageenan and purified ι-carrageenan It is preferable to use a mixture.

  As a method for obtaining the purified iota-carrageenan, it can be obtained by producing E. spinosum algae belonging to the genus Myrhinaceae as red algae in accordance with the production method of the purified carrageenan.

  The mixing ratio of purified κ-carrageenan and purified ι-carrageenan in terms of mass is not particularly limited, but is 100: 0 to 1:99, preferably 45:55 to 20:80, and more preferably 45:55 to 30. : 70. When the amount of purified κ-carrageenan is larger than 45:55, water separation and shrinkage are insufficient, the gel becomes too hard and sufficient elasticity does not come out, and the merchantability as a gel-like fragrance decreases. End up. Further, when the amount of purified κ-carrageenan is less than 30:70, sufficient shape retention is not achieved.

  The blending amount of the purified carrageenan as a gelling agent in the gel composition of the present invention is 0.1% to 10%, preferably 0.5% to 5%, more preferably 1% to 3%. %. When it is less than 0.1%, it does not gel but forms a sol. When it is more than 10%, there is a large amount of residue after use. Production is difficult.

  As a volatile chemical | medical agent used for the transparent gel-like composition of this invention, an insect repellent, an insecticide, a repellent, a fragrance | flavor, a deodorizing agent etc. can be mentioned, for example.

  Among the volatile chemicals, examples of the insecticide and insecticide include pyrethroid insecticides such as enpentrin, transfluthrin, allethrin, phenothrin, metfurthrin, profluthrin, paradichlorobenzene, naphthalene, camphor, 2-phenoxyethanol, etc. These 1 type (s) or 2 or more types can be mixed and used.

  Further, as the fragrance, for example, animal fragrance such as musk, ghost cat fragrance, Ryunobu fragrance, Abies oil, Akjon oil, Almond oil, Angelica root oil, paging oil, bergamot oil, perch oil, bore bellows oil, kayabuchi oil, Gananga oil, capsicum oil, caraway oil, cardamom oil, cassia oil, celery oil, cinnamon oil, citronella oil, cognac oil, coriander oil, cumin oil, camphor oil, jill oil, estgolan oil, eucalyptus oil, fennel oil, garlic Examples include vegetable flavors such as oil, ginger oil, grapefruit oil, hop oil, lemon oil, lemongrass oil, nutmeg oil, mandarin oil, mint oil, orange oil, sage oil, star anise oil, and turpentine oil. As this fragrance, artificial fragrance such as synthetic fragrance or extracted fragrance can also be used. For example, hydrocarbon fragrance such as pinene and limonene, linalool, geraniol, citronellol, menthol, borneol, benzyl alcohol, anis alcohol, β-phenethyl alcohol Alcohol flavors such as Anetol, Eugenol, etc., n-butyraldehyde, isobutyraldehyde, hexylaldehyde, citral, citronellal, aldehydes such as benzaldehyde, cinnamic aldehyde, flavors, carvone, menthone, camphor, acetophenone, ionone Ketone flavors such as γ-butyl lactone, coumarin, cineol and other lactone flavors, octyl acetate, benzyl acetate, cinnamyl acetate, butyrate propionate And ester-based fragrances such as methyl benzoate. Furthermore, the blended fragrance | flavor which mixed 2 or more types of the said fragrance | flavor can also be used.

  Further, as deodorizers, metal salts of inorganic acids such as aluminum sulfate, ammonium chloride, alum, copper sulfate, zinc sulfide, metal salts of organic acids such as zinc stearate and aluminum stearate, titanium oxide and zinc oxide And metal oxides such as flavonoid compounds, plant extracts such as catechins and polyphenols or derivatives thereof, cyclodextrins or derivatives thereof, zeolites, activated carbon and the like.

  Although the compounding quantity of the volatile chemical | medical agent in the gel-form chemical | medical agent of this invention is not specifically limited, It is 0.01 to 30% in a composition, Preferably it is 0.1 to 10%, More preferably, it is 1 to 10%. . If it is less than this, a sufficient effect may not be obtained, and if it is more than this, it may be colored, transparency may be inferior, or a gel may not be formed.

  The volatile chemical may be either aqueous or oily, but when an oily chemical is used, it is preferable to use a surfactant. As this surfactant, any one of conventionally known anionic surfactants, cationic surfactants, nonionic surfactants or amphoteric surfactants can be used, and one or more of these can be used. Can also be used in combination.

  Among the surfactants, anionic surfactants include, for example, higher fatty acid soap, soap base, metal soap, N-acyl-L-glutamate triethanolamine, N-acyl-L-glutamate sodium, sodium alkyl sulfate Sodium alkyl sulfonate, sodium dialkyl sulfosuccinate, polyoxyethylene alkyl ether sodium sulfate, polyoxyethylene alkyl ether phosphoric acid, polyoxyethylene alkyl phenyl ether phosphoric acid, coconut oil fatty acid methyl taurine sodium (N-cocoyl-N-methyl) Taurine sodium), lauryl sulfate triethanolamine, sodium lauryl sulfate, lauroyl sarcosine sodium, lauroyl methyl β-alanine sodium solution, lauroyl methyl taurine sodium It can be used by mixing one or two or more of such um.

  Examples of the cationic surfactant include ethyl lanolin sulfate fatty acid aminopropylethyldimethylammonium chloride, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, distearyldimethylammonium chloride, stearyldimethylbenzylammonium chloride, stearyltrimethylammonium chloride, benzalkco chloride. One kind or a mixture of two or more kinds such as nium and benzethonium chloride can be used.

  Furthermore, examples of the nonionic surfactant include polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene hydrogenated castor oil ether, polyoxyethylene sorbitan ester, fatty acid alkanolamide, and tertiary amine oxide. In this polyoxyethylene alkyl ether, the polyoxyethylene chain has 3 to 18, preferably 7 to 12, the alkyl chain may be either linear or branched, and the alkyl chain length is 8 to 22, preferably 12 to 14. Examples of the fatty acid alkanolamide include coconut oil fatty acid, stearic acid, lauric acid monoethanolamide, diethanolamide, and the like. Examples of the tertiary amine oxide include lauryl dimethylamine oxide and coconut oil fatty acid dimethylamine oxide. Is mentioned.

  Furthermore, as the amphoteric surfactant, one or more kinds of 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldiaminoethylglycine hydrochloride, lauryldimethylaminoacetic acid betaine, etc. are mixed. Can be used.

  Of the above-mentioned surfactants, it is preferable to use a nonionic surfactant in terms of high emulsification / solubilization ability, little reduction in gel strength, and little occurrence of water separation. Among nonionic surfactants, it is particularly preferable to use amine surfactants such as fatty acid alkanolamides and tertiary amine oxides.

  The blending amount of the surfactant in the transparent gel composition of the present invention can be appropriately selected depending on the kind and amount of the oil component to be blended, but is 0.01 to 30%, preferably 0.0 in the composition. It is 1-20%, More preferably, it is 1-15%. If it is less than this, the oily component cannot be dispersed or solubilized, which may affect the stability of the gel. Moreover, when more than this, a gel may not be formed.

  The gelled drug of the present invention may further contain a gelation accelerator for the purpose of improving the gel strength and the gel melting point. Examples of the gelation accelerator include conventionally known gelation accelerators. For example, one or more of sodium salt, potassium salt, calcium salt, magnesium salt and the like can be mixed and used. Of these, the use of monovalent alkali metal salts such as potassium chloride and sodium chloride, especially potassium chloride, in order to maintain transparency during volatilization and optimize the gel melting point during use maintains transparency. However, it is preferable because the effect of improving the gel melting point is high. Usually, when these salts are blended as a gelation accelerator, the transparency is lowered, but when used in a gelled drug using the purified carrageenan of the present invention, the gel melting point is improved while maintaining the transparency. The gel strength can be improved.

  The blending amount of the gelation accelerator is not particularly limited, but is 0.01% to 0.5%, preferably 0.1% to 0.3%. If it is less than 0.01%, there is no effect of improving the gel melting point, and the gel may be dissolved in a relatively hot place or in summer. If it is more than 0.5%, it gels rapidly and becomes a uniform gel. Production is difficult and water separation may occur.

  The gel-like drug of the present invention can be used within the range not impairing the effects of the present invention, if necessary, alcohol solvents such as ethanol, isopropyl alcohol, propyl alcohol, glycol solvents such as propylene glycol and ethylene glycol, ethylene glycol Increase in solvents such as monomethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, glycol ether solvents such as 3-methoxy-3-methyl-1-butanol, other gelling agents such as gellan gum, locust bean gum, etc. It is also possible to add a sticky agent, an antifungal agent, an antibacterial agent, an ultraviolet absorber, an antioxidant, a pigment, an efficacy enhancer, a deodorant and the like.

  The method for producing the gel-like drug of the present invention can be produced by a conventionally known method. In particular, when a mixture of purified κ-carrageenan and purified ι-carrageenan is used, it can be produced by the following method. It is preferable because it is easy to stir and can be produced efficiently.

  That is, purified carrageenan dispersed in a solvent if necessary and gelling accelerator if necessary are added to water heated to 80 ° C. or higher and stirred. To this liquid, add a volatile agent, a surfactant, and if necessary, a solvent and agitate and mix in water, mix, sufficiently agitate, fill in a suitable container, cool and cool to the gel state of the present invention. A drug can be obtained.

  The gel-like drug of the present invention thus prepared is installed in a room, toilet, closet, shoebox, chest, closet, clothes case, car interior, etc. as a fragrance, deodorant, insect repellent, etc. Medicinal effects can be imparted.

  EXAMPLES Next, although an Example is given and this invention is demonstrated in more detail, this invention is not restrict | limited at all by these Examples.

Manufacturing example 1
Production of purified κ-carrageenan:
E. of Solieriaceae (Eucheuma) as a raw red algae. Using 5.5 tons of the cotton algae dried in the sun, this was put in 25 t of a 10% aqueous potassium hydroxide solution and extracted at 85 to 90 ° C. for 90 minutes. Thereafter, 20 t of ion-exchanged water and 300 kg of pearlite as a body feed were added to the obtained extracted solution, and this was filtered at a pressure of 5 bar using a filter precoated with pearlite. The obtained filtrate (50 t) was filtered and concentrated using an ultra filter (manufactured by Advanced Membrane Technology) at a pressure of 2 bar. The obtained concentrate (25t) was jetted into 70% by mass of isopropyl alcohol (25t), precipitated, separated, and dried at 85 ° C. to obtain purified κ-carrageenan 1t.

Manufacturing example 2
Production of purified ι-carrageenan:
As raw material red algae, E. of Solieriaceae Eucheuma (Eucheuma). Using 5.5 tons of spinosum original algae dried in the sun, this was put into 25 t of 10% aqueous potassium hydroxide solution and extracted at 85 to 90 ° C. for 90 minutes. Thereafter, 20 t of ion-exchanged water and 300 kg of pearlite as a body feed were added to the obtained extracted solution, and this was filtered at a pressure of 5 bar using a filter precoated with pearlite. The obtained filtrate (50 t) was filtered and concentrated using an ultra filter (manufactured by Advanced Membrane Technology) at a pressure of 2 bar. The obtained concentrate (25t) was jetted into 70% by mass of isopropyl alcohol (25t), precipitated, separated, and dried at 85 ° C. to obtain purified ι-carrageenan 1t.

Test example 1
Measurement of nitrogen content and calcium content in purified carrageenan The nitrogen content and calcium content of the purified carrageenan produced in Production Example 1 and Production Example 2 were measured by the following methods.

Nitrogen content:
The nitrogen content was calculated based on the nitrogen content measured by the Kjeldahl method. That is, a sample (Sg) was collected in a Kjeldahl decomposition flask, 10 g of a mixture of copper sulfate and potassium sulfate (1: 9) and 15 ml of concentrated sulfuric acid were added as decomposition accelerators, and the mixture was thermally decomposed until it became transparent. Even after becoming transparent, the mixture was further heated for 60 minutes and then allowed to cool, and 100 ml of ion-exchanged water and 80 ml of 30% sodium hydroxide were added, followed by heating and distillation under excess alkali, and 150 ml of a distillate was collected. The collected distillate was titrated with a 0.005 mol / L sulfuric acid standard solution using a bromcresol green / methyl red mixed reagent as an indicator <v ml>. The nitrogen content was determined by the following calculation formula.

Ｖ：本試験滴定量（ｍｌ）
Ｂ：空試験滴定量（ｍｌ）
Ｆ：０.００５ｍｏｌ／Ｌ硫酸標準溶液の力価
０.０００１４： ０.００５ｍｏｌ／Ｌ硫酸標準溶液１ｍｌに対する窒素量（ｇ）
Ｓ：試料採取量（ｇ）

V: Final test titration (ml)
B: Blank test titration (ml)
F: Potency of 0.005 mol / L sulfuric acid standard solution 0.00014: Nitrogen amount per 1 ml of 0.005 mol / L sulfuric acid standard solution (g)
S: Sampling amount (g)

Calcium content:
Samples 2 to 6 g were collected in a beaker and incinerated at 500 ° C. for 5 to 6 hours in an electric furnace. The product added with 20% hydrochloric acid was evaporated on a hot plate. Further, 20% hydrochloric acid was added to this and heated with a hot plate. The mixture was filtered with 5A and the volume was adjusted with a volumetric flask. The calcium content was determined by measuring at a wavelength of 317.933 nm using an IPC emission spectrometer (Spectrophotometer UV2450, manufactured by Shimadzu Corporation).

  Table 1 shows the nitrogen content and the calcium content per 100 g of the purified carrageenan obtained in Production Examples 1 and 2. Table 1 also shows the nitrogen content and the calcium content per 100 g of the purified carrageenan measured by the above method.

Example 1
Gel fragrance deodorant:
Using the purified κ-carrageenan produced in Production Example 1 (hereinafter referred to as “purified κ-carrageenan”) and the purified ι-carrageenan produced in Production Example 2 (hereinafter referred to as “purified ι-carrageenan”), the gel-like fragrance was removed according to the formulation shown in Table 2. An odorant was produced. As comparative products, κ-carrageenan and ι-carrageenan purified by a conventional alcohol precipitation method and κ-carrageenan purified by a gel press method (manufactured by Takaragen: BK-20P) were used. About each obtained gel-like fragrance | flavor, the transparency was evaluated by the following method. The results are shown in Table 3.

(How to)

(Transparency evaluation method)
1 kg of the obtained gel was placed in a glass container having a length of 10 cm, a width of 10 cm, and a height of 10 cm. The entire gel was visually observed by 10 monitors, the transparency was evaluated according to the following criteria, and the average value was obtained.

Score status
5: Completely transparent
4: Almost transparent
3: Slightly cloudy
2: Somewhat cloudy
1: Cloudy

(Result)

Example 2
Gel fragrance Purified carrageenan dispersed in 10 g of ethanol and 1.0 g of propylene glycol (1.0 g of purified κ carrageenan produced in Production Example 1 and 1.5 g of purified ι-carrageenan produced in Production Example 2 were mixed. 2.5 g of the product) was added to water heated to 80 ° C. or more together with the gelation accelerator shown in Table 4 below and stirred. To this liquid, 3.0 g of citrus fragrance as a volatile agent in water and a surfactant (4.5 g of polyoxyethylene (n = 15) alkyl (C ₁₈ ) ether and 1.5 g of lauryldimethylamine oxide) were added. The mixture was added and stirred, and water was further added to make the total amount 100 g. This was filled in a glass container having an upper surface opening of 50 mm length × 50 mm width × 80 mm height, and cooled to obtain a gel-like fragrance.

  About the gel-like fragrance | flavor created above, the transparency was evaluated by the method similar to Example 1, and gel melting | fusing point and gel strength were measured with the following method. The results are also shown in Table 4.

(Measurement of gel melting point)
10 g of the dissolved gel is placed in a test tube having a diameter of 12 mm, which is slanted and solidified into a slope shape. This was placed in a hot water bath, and the temperature at which the upper gel began to melt was measured as the gel melting point.

(Measurement of gel strength)
40 g of the dissolved gel is put in a glass container having a diameter of 30 mm and a depth of 70 mm, covered, and cooled and solidified at room temperature. The breaking strength of the gel was measured with a rheometer (manufactured by Sun Kagaku Co., Ltd.) equipped with a cylindrical jig with a diameter of 10 mm to obtain the gel strength.

From the above results, it was found that KCl is preferable to CaCl ₂ for the gelation accelerator.

Example 3
Gel repellent Purified carrageenan dispersed in 10 g of ethanol and 1.0 g of propylene glycol (1.0 g of purified κ-carrageenan produced in Production Example 1 and 1.5 g of purified ι-carrageenan produced in Production Example 2) ) 2.5 g was added to water heated to 80 ° C. or more together with 0.1 g of NaCl as a gelation accelerator and stirred.

In this liquid, a repellent (1 g of linalool, 0.5 g of citronellol, 0.5 g of citronellal) as a volatile agent, 2.0 g of surfactant (polyoxyethylene (n = 15) alkyl (C ₁₈ ) ether) and lauryl Dimethylamine oxide (1.5 g) was added and mixed. This was filled into a polypropylene container having a top opening of 50 mm length × width 50 mm × height 80 mm and cooled to obtain a gel repellent.

  The obtained gel repellent was transparent, and a repellent effect was observed against chironomids and fly flies for about 2 months. Also, there was no water separation during the period of use, and a clear end point was shown after 2 months.

Example 4
Gel repellent Purified carrageenan dispersed in 10 g of ethanol and 1.0 g of propylene glycol (1.0 g of purified κ-carrageenan produced in Production Example 1 and 1.5 g of purified ι-carrageenan produced in Production Example 2) ) 2.5 g was added to water heated to 80 ° C. or more together with 0.1 g of KCl as a gelation accelerator and stirred.

To this liquid, 2.0 g of phenoxyethanol as a volatilizing agent and a surfactant (2.0 g of polyoxyethylene (n = 15) alkyl (C ₁₈ ) ether and 1.5 g of lauryldimethylamine oxide) are mixed in water. And stirred. This was filled into a polypropylene container having a top opening of 50 mm length × width 50 mm × height 80 mm and cooled to obtain a gel insect repellent.

  The obtained gel-like insect repellent was transparent, and was found to have an effect of suppressing food damage against clothing pests such as squid and carp for about 2 months. Also, there was no water separation during the period of use, and a clear end point was shown after 2 months.

  The transparent gel-like composition of the present invention is an aqueous gel that has high transparency and does not cause water separation as compared with a conventional product using carrageenan. In addition, this gel is rich in elasticity, and the shrinkage of the gel that accompanies the volatilization of the compounding components shrinks in a similar shape to the storage container, so the texture is good, the end point of volatilization is clear, and it looks good It has the feature of being good.

Therefore, the transparent gel composition of the present invention can be advantageously used as a gel preparation for volatilizing volatile drugs such as insect repellents, insecticides, repellents, fragrances and deodorants.

that's all

Claims (10)

  A transparent gel composition containing a gelling agent, a volatile agent, a surfactant and water, wherein the nitrogen content in the dried product as a gelling agent is 0.01% by mass or less, and the calcium content per 100 g is A transparent gel composition comprising purified κ-carrageenan of 25 mg or less.   The transparent gel composition according to claim 1, wherein the gelling agent further comprises purified iota-carrageenan having a nitrogen content in a dried product of 0.04 mass% or less and a calcium content per 100 g of 35 mg or less.   Purified κ-carrageenan having a nitrogen content of 0.01% by mass or less in a dried product and a calcium content per 100 g of 25 mg or less extracts a red algae original algae with an alkaline aqueous solution, and then adds a filter aid to the extracted aqueous solution. Filtering is carried out while applying pressure, and the obtained filtrate is concentrated by an ultrafilter, and is obtained by purifying by spraying and precipitating in an aqueous alcohol solution, separating and drying. The transparent gel composition according to 1.   Purified iota-carrageenan having a nitrogen content of 0.04% by mass or less in a dried product and a calcium content of 35 mg or less per 100 g is extracted with an alkaline aqueous solution, and then a filter aid is added to the extracted aqueous solution. Filtering is performed while adding and pressurizing, and the obtained filtrate is concentrated by an ultrafilter, sprayed and precipitated in an aqueous alcohol solution, separated and dried to obtain a purified product. The transparent gel composition according to Item. Purified κ-carrageenan having a nitrogen content in a dried product of 0.01% by mass or less and a calcium content per 100 g of 25 mg or less, and a nitrogen content in a dried product of 0.04% by mass or less and calcium per 100 g The transparent gel composition according to claim 2 or 4, wherein the mass mixing ratio of the purified iota-carrageenan having a content of 35 mg or less is 45:55 to 20:80. The transparent gel composition according to any one of claims 1 to 5 , wherein the volatile agent is a fragrance, an insect repellent or a deodorant. The transparent gel composition according to any one of claims 1 to 6, further comprising a gelation accelerator. The transparent gel composition according to claim 7, wherein the gelation accelerator is a monovalent alkali metal salt. Purified κ-carrageenan having a nitrogen content in a dried product of 0.01% by mass or less and a calcium content of 100 mg or less of 25 mg or less as a gelling agent in water heated to 80 ° C. or higher is dispersed in a solvent. And then adding a solution in which a volatile drug is dissolved or dispersed in advance, and then mixing the liquid mixture into a container and cooling. . The method for producing a transparent gelled drug according to claim 9 , wherein a purified iota-carrageenan having a nitrogen content in a dried product of 0.04 mass% or less and a calcium content per 100 g of 35 mg or less is further used as a gelling agent. .