JP5026734B2 - Deodorants - Google Patents

Description

  The present invention relates to a deodorant, and more particularly, to a deodorant that can reduce a complex odor derived from fatty acids, aldehydes, and amines and is safe for the human body.

A deodorant relieves an unpleasant odor together with a fragrance, and plays an important part in living a comfortable life. Recent needs regarding deodorization have changed from a fragrance that masks bad odor with a strong fragrance to a deodorant that eliminates the odor itself with a slight fragrance or no fragrance.
In addition, while there is an increasing laundry habit of wearing clothes that do not touch the skin directly, they do not wash immediately, but on the other hand, they are concerned about the smell of clothes that are not washed. Most of the unpleasant odors in the living environment are complex odors. For example, sweat odors are closely related to lower fatty acids such as isovaleric acid, and raw garbage odors are deeply related to amines typified by trimethylamine and sulfur compounds such as methyl mercaptan. .

Conventionally, chemical deodorants effective for specific malodor components are known, but there are few effective chemical deodorants, and there is a need for deodorizers effective for this composite odor.
For example, Patent Document 1 discloses a tooth brush that erases bad breath using glucosamine. However, although it may be effective for deodorizing sulfur compounds such as methyl mercaptan, no deodorizing effect on aldehydes other than bad breath has been studied. Moreover, even if a glucosamine is used as it is and a water-based deodorant is prepared, it is not effective with respect to the amine odor derived from garbage etc.
Patent Document 2 discloses that a deodorant containing chitosan (basic polysaccharide) dissolved at a pH of 1 to 5 is effective for garbage and manure odor. However, this deodorant is not effective against fatty acid odor or aldehyde odor. Chitosan is insoluble in water and is not suitable as an aqueous deodorant.

Patent Document 3 discloses that a deodorant containing ethanolamine is effective for deodorizing unsaturated aldehydes such as nonenal and octenal, which are considered as one of the causative substances of aging odors recognized after middle-aged and older. ing. However, regarding ethanolamine, the effect on fatty acid odor, amine odor, etc. is unknown, and ethanolamine is irritating and is not suitable for use in a form that may touch the human body.
Patent Document 4 discloses that a deodorant using an amide or ester hydrochloride of an amino acid such as glycine or lysine is excellent in deodorizing activity of aldehydes. However, in the amino acid amide and ester hydrochlorides disclosed in Patent Document 4, when used as an aqueous deodorant, the deodorizing effect is not expressed against the aldehyde, or the deodorizing performance against the aldehyde is expressed, Undesirable odor due to decomposition is not preferable.

Under such circumstances, it has been desired to develop a deodorant that can reduce a complex odor derived from fatty acids, aldehydes, and amines and is safe for the human body.
In addition, as substances that impair health and living environment, the specified substances specified in the Ordinance on Enforcement of the Air Pollution Control Law and the specified malodorous substances specified in the Ordinance on Odor Prevention Law include lower fatty acids such as isovaleric acid, amines such as ammonia and trimethylamine, formaldehyde, and acetaldehyde. Therefore, removal of these fatty acids, amines and aldehydes is an important issue.

JP-A-48-23946 Japanese Patent Laid-Open No. 11-253541 JP 2001-97838 A JP 2002-95726 A

  The present invention provides a deodorant that can reduce complex odors derived from fatty acids, aldehydes, and amines, is easy to prepare a water-based deodorant, and is safe to touch the human body. Is an issue.

The inventors of the present invention have found that specific amino monosaccharide salts are effective for deodorizing complex odors derived from fatty acids and aldehydes. By adjusting the pH to near neutrality, ammonia and amines can be eliminated. It was found that it is effective against odors, does not generate off-flavors due to decomposition, and has little irritation to the human body.
That is, the present invention provides the following (1) to (4) .
(1) A deodorant containing a salt of an amino monosaccharide (excluding N-methylglucamine) and water and having a pH of 6.5 to 9.5.
(2) A deodorizing method using the deodorizer according to (1), which reduces a complex odor derived from fatty acids, aldehydes and amines.
(3) A deodorizing method using the deodorizer of (1) for a textile product, a hard surface, or a space.
( 4 ) A deodorizing method for reducing the odor of an object by attaching the deodorant of (1) to the object.

The deodorant of the present invention can deodorize complex odors derived from fatty acids, aldehydes and amines, is easy to prepare a water-based deodorant, and is safe to touch the human body. Exhibits excellent deodorizing effect against complex odor present on the surface or space.
Moreover, according to the deodorizing method of this invention, the complex odor originating in fatty acids, aldehydes, and amines can be deodorized simply and effectively.

The deodorant of the present invention contains an amino monosaccharide or a salt thereof and water, and has a pH of 6.5 to 9.5.
An amino monosaccharide is a compound in which the hydroxyl group of a monosaccharide is substituted with an amino group. As the amino monosaccharide, glucosamine, mannosamine, galactosamine, glucamine and the like are preferable. Among these, glucosamine, mannosamine, galactosamine, and glucamine are more preferable from the viewpoint of deodorizing performance, and glucosamine is particularly preferable from the viewpoint of availability.
In the present invention, amino monosaccharides are not significantly different in performance regardless of whether they are optically active, racemic, or mixtures thereof, but the D-form is preferred from the viewpoint of availability.
Amino monosaccharides or salts thereof can be used alone or in admixture of two or more.

  The content of the amino monosaccharide or the salt thereof in the present invention varies depending on the concentration of malodor to be deodorized and the use form, but it may be contained in an amount of 0.001% by weight or more from the viewpoint of deodorizing performance, preferably It is 0.005-30 weight%, More preferably, it is 0.01-10 weight%, Especially preferably, it is 0.03-5 weight%.

The deodorizer of the present invention has a pH of 6.5 to 9.5. An effect on fatty acids and aldehydes is exhibited when the pH is 6.5 or more, and an effect on amines is exhibited when the pH is 9.5 or less. From the viewpoints of effects on all fatty acids, amines, aldehydes, and reduction of irritation to the skin, the pH is preferably 6.5 to 9.0, more preferably 7.0 to 9.0.
In order to maintain the pH of the deodorant of the present invention at 6.5 to 9.5, preferably 6.5 to 9.0, more preferably 7.0 to 9.0, in addition to hydrochloric acid, sulfuric acid, nitric acid, phosphorus Acid, carbonic acid, acetic acid, lactic acid, succinic acid, malic acid, citric acid, mono (short and medium chain alkyl, glucose, etc.) substituted phosphate ester, maleic acid, malonic acid, ethylenediamine polyacetic acid, cycloalkane alkene-1, 2-dicarboxylic acid, diethylenetriamine polyacetic acid, 1,2-cyclohexanediamine-N-polyacetic acid and the like can be used.

In the deodorizer of the present invention, the addition of a compound having an acid dissociation index (pKa) (25 ° C.) of 5.0 or more in at least one dissociation stage only increases the pH buffering ability near neutrality. Rather, it also works effectively on deodorization of fatty acids and amines, and even if the amount of amino monosaccharides is reduced, sufficient deodorization against complex odors derived from fatty acids, aldehydes and amines It is preferable because of the effect.
Here, the acid dissociation index is, for example, (a) the method described in The Journal of Physical Chemistry vol. 68, number 6, page 1560 (1964), (b) an automatic potentiometric titrator (COM-980Win, etc.) manufactured by Hiranuma Sangyo Co., Ltd. ) And the acid dissociation index described in (c) Chemical Handbook of the Chemical Society of Japan (Revised 3rd edition, published June 25, 1984, published by Maruzen Co., Ltd.), ( d) A database such as pKaBASE manufactured by Compudrug can be used.

Examples of the compound having an acid dissociation index (pKa) (25 ° C.) of 5.0 or more in at least one dissociation stage include inorganic acids and organic acids.
Examples of such inorganic acids include carbonic acid (first stage pKa value: 6.35, second stage pKa value: 10.33), phosphonic acid (second stage pKa value: 6.79), phosphoric acid (second stage PKa value: 7.20, third stage pKa value: 12.35), diphosphoric acid (third stage pKa value: 6.70, fourth stage pKa value: 9.40), tripolyphosphoric acid (fourth stage) pKa value: 6.50, fifth-stage pKa value: 9.25), and the like.
Examples of the organic dibasic acid having an acid dissociation index (pKa) of 5.0 or more include, for example, maleic acid (second-stage pKa value: 5.83. The numerical value in parentheses below is the second-stage pKa. Value)), malonic acid (5.28), 2-methylmalonic acid (5.76), 2-ethylmalonic acid (5.81), 2-isopropylmalonic acid (5.88), 2,2 -Dimethylmalonic acid (5.73), 2-ethyl-2-methylmalonic acid (6.55), 2,2-diethylmalonic acid (7.42), 2,2-diisopropylmalonic acid (8.85) , M-hydroxybenzoic acid (9.96), p-hydroxybenzoic acid (9.46), 1,2-cyclohexanedicarboxylic acid (trans isomer: 6.06, cis isomer: 6.74), 1,2- Cyclopentanedicarboxylic acid (trans isomer: 5.99, cis isomer: 6.57) 1,2-cyclooctanedicarboxylic acid (trans isomer: 6.24, cis isomer: 7.34), 1,2-cycloheptanedicarboxylic acid (trans isomer: 6.18, cis isomer: 7.6), succinic acid (5.24), phenylsuccinic acid (5.55), 2,3-dimethylsuccinic acid (6.0), 2,3-diethylsuccinic acid (6.46), 2-ethyl-3-methylsuccinic acid ( 6.1), tetramethylsuccinic acid (7.41), 2,3-di-t-butylsuccinic acid (10.26), 3,3-dimethylglutaric acid (6.45), 3,3-diethylglutar Acid (7.42), 3-isopropyl-3-methylglutaric acid (6.92), 3-tert-butyl-3-methylglutaric acid (7.49), 3,3-diisopropylglutaric acid (7.68) ), 3-methyl-3-ethylglutaric acid ( .70), 3,3-dipropylglutaric acid (7.48), 2-ethyl-2- (1-ethylpropyl) glutaric acid (7.31), cyclohexyl-1,1-diacetic acid (7.08) ), 2-methylcyclohexyl-1,1-diacetic acid (6.89), cyclopentyl-1,1-diacetic acid (6.77), 3-methyl-3-phenylglutaric acid (6.17), 3- And ethyl-3-phenylglutaric acid (6.95).

Examples of other organic polybasic acids having an acid dissociation index (pKa) of 5.0 or more include citric acid (third-stage pKa value: 5.69).
Among these, phosphoric acid, citric acid, succinic acid, maleic acid, malonic acid and the like, which are easily available and have an acid dissociation index (pKa) of at least 5.2 in at least one dissociation stage, are preferable.

When amino monosaccharide is used as a salt such as hydrochloric acid, the pH can be adjusted to 6.5 to 9.5 by adding a base.
Examples of the base that can be used include sodium hydroxide, potassium hydroxide, magnesium hydroxide, calcium hydroxide and the like, as well as monoethanolamine, diethanolamine, triethanolamine, methylethanolamine, dimethylethanolamine and the like. Among these, sodium hydroxide and potassium hydroxide are preferable. These can be used alone or in admixture of two or more.

In the deodorizer of the present invention, the remainder other than the amino monosaccharide or a salt thereof or a compound having an acid dissociation index (pKa) of 5.0 or more can be water. The water to be used is preferably one obtained by removing ionic components from distilled water, ion-exchanged water or the like.
In the present invention, polyhydric alcohols, surfactants, other deodorants, and various commonly used solvents, oils, gelling agents, sodium sulfate and N, as long as the effects of the present invention are not impaired. Other components such as a salt such as N, N-trimethylglycine, a pH adjuster, an antioxidant, an antiseptic, a bactericidal / antibacterial agent, a fragrance, a dye, and an ultraviolet absorber can be added.
Polyhydric alcohols and surfactants not only suppress the volatilization of malodorous components attached to textiles, hard surfaces, human bodies, pets, etc., but also stably disperse amino monosaccharides or their salts as deodorizing components. The contact with malodorous components can be improved and the deodorizing effect can be further enhanced.

Examples of polyhydric alcohols that can be used include glycerin, ethylene glycol, propylene glycol, 1,3-propanediol, butanediol, diethylene glycol, dipropylene glycol, polyethylene glycol, polypropylene glycol, and the like. Among these, diethylene glycol and dipropylene glycol are preferable.
The content of the polyhydric alcohol used varies depending on the concentration of malodor to be deodorized and the use form, but is usually 0.001% by mass or more, preferably 0.001 to 30% by mass, and more preferably 0.005 to 5%. 10% by mass.

There is no restriction | limiting in particular as surfactant which can be used, An anionic surfactant, a cationic surfactant, an amphoteric surfactant, and a nonionic surfactant are mentioned.
Specifically, the molecule has at least an alkyl group or alkenyl group having 8 to 18 carbon atoms, and the hydrophilic portion includes a carboxylate, a sulfonate, a sulfate ester salt, a phosphate ester salt, a quaternary ammonium salt. , Sulfobetaine, carbobetaine, amine oxide, (poly) oxyalkylene, (poly) alkanolamine, (poly) glycoside, and a compound having a (poly) glycerin skeleton. Moreover, the C8-C18 alkyl group or alkenyl group and the hydrophilic part may be bonded via one or more selected from an ether group, an ester group, an amide group, and an alkyl group.
Among these surfactants, sulfonate, sulfate ester, phosphate ester salt, quaternary ammonium salt, carbobetaine, amine oxide, (poly) glycoside, and (poly) glycerin type surfactants are preferable.
The content of the surfactant to be used varies depending on the concentration of malodor to be deodorized and the use form, but is usually 0.001% by mass or more, preferably 0.001 to 30% by mass, more preferably 0.01 to 10%. % By mass.

  Solvents that can be used include, for example, ethanol, monoethyl or monobutyl ether of ethylene glycol or propylene glycol, monoethyl or monobutyl ether of diethylene glycol or dipropylene glycol, benzyl alcohol, benzyloxyethanol, ethylene oxide or propylene oxide addition of phenolic compounds Thing etc. are mentioned.

The use form of the deodorant of the present invention can be liquid, gelled, powdery, granular or other solid form, but is preferably used in liquid form. In the case of liquid, especially as sprays and lotions, fabrics such as handkerchiefs and towels, clothing such as suits and sweaters, textile products such as curtains and sofas, cooking utensils such as tableware and pans, countertops, ranges, floors, It is suitable for deodorizing walls, wallpaper, trash cans, toilets, bathtubs, drains, and other hard surfaces, human bodies such as skin and hair, pets, and spaces. Moreover, it can also be used as a stationary type, such as being used as a filter of an air purifier by being immersed and sprayed on paper or non-woven fabric.
The deodorant of the present invention is particularly preferably a water-based deodorant that is filled in a mist type spray container and the spray amount per time is adjusted to 0.1 to 1 ml. As a spray container to be used, a known spray container such as a trigger spray container (direct pressure or pressure accumulation type) or a dispenser type pump spray container can be used.
The object of the deodorizing method using the deodorant of the present invention is not particularly limited, such as a textile product, a material having a hard surface, a human body, a pet, and a space.

In the following Examples, Comparative Examples, and Preparation Examples, “%” means “mass%”.
Examples 1-5
(Preparation of deodorant)
Ion exchange water is added to 0.50 g of the deodorant base shown in Table 1 to make 10 g, and a 48% NaOH aqueous solution or concentrated hydrochloric acid is added to adjust the pH shown in Table 1 to 5% deodorant aqueous solution. Prepared.

(Measurement of deodorization performance)
400 mg of the prepared 5% deodorant aqueous solution is put into a 100 mL bottle with a lid, and as an odor component, an odor component aqueous solution of 2% isovaleric acid aqueous solution 100 μL, 8.4% ammonia aqueous solution 1 μL, 0.35% acetaldehyde aqueous solution 10 μL. Each was added separately and sealed. Next, in the case of isovaleric acid, it was shaken in a 30 ° C. water bath, and in the case of ammonia and acetaldehyde, it was shaken at room temperature for 20 minutes. . The same sample was tested three times to determine its average gas concentration (S). Moreover, the average gas concentration (C) when it carried out similarly using ion-exchange water was calculated | required, and the deodorizing rate (%) was calculated | required by following Formula. The results are shown in Table 1.
Deodorization rate (%) = [1- (S / C)] × 100

Comparative Examples 1-3
Deodorized performance was measured in the same manner as in the Examples, respectively, by preparing acidified and dissolved chitosan and 5% aqueous solution of acidified or strongly alkaline glucosamine hydrochloride. The results are shown in Table 1.

  From Table 1, in Comparative Examples 1 and 2 made into an acidic solution, the deodorizing performance against isovaleric acid and acetaldehyde was low, and in Comparative Example 3 made into a strong alkaline solution, the deodorizing performance against ammonia was low. As the odorant, high deodorizing performance was recognized for any of isovaleric acid, ammonia, and acetaldehyde.

Formulation Examples 1-8
Table 2 shows formulation examples using the deodorant of the present invention containing an amino monosaccharide or a salt thereof and water. The fragrance used was 5 parts of ethyl cinnamate, 10 parts of linalyl acetate, 15 parts of laral part, 10 parts of hexylcinnamic aldehyde, 10 parts of parride, 20 parts of phenylethylaldehyde, 10 parts of cedar alcohol, and 20 parts of limonene. It is a blended fragrance made of

  The deodorizer of the present invention can deodorize complex odors derived from fatty acids, aldehydes, and amines, is easy to prepare an aqueous deodorant, and is safe to touch the human body. For this reason, the deodorizer of this invention can be used conveniently as a deodorizer of the composite odor which exists in textiles, a hard surface, space, etc.

Claims (9)

A salt of amino monosaccharide (excluding N-methylglucamine) and water, and a compound having an acid dissociation index (pKa) (at 25 ° C.) of at least 5.0 in at least one dissociation stage , and a pH of 6 Deodorant which is .5 to 9.5.   The deodorizer according to claim 1, wherein the amino monosaccharide is glucosamine, mannosamine, galactosamine, or glucamine. Furthermore, the deodorizer of Claim 1 or 2 containing a polyhydric alcohol. Having an alkyl or alkenyl group having 8 to 18 carbon atoms in the molecule, it contains a surfactant having an amine oxide or (poly) oxyalkylene skeleton in the hydrophilic part, of any of claims 1-3 Deodorants. The deodorant in any one of Claims 1-4 containing ethanol. The deodorant according to any one of claims 1 to 5 , wherein the deodorant is an aqueous deodorant. The deodorizing method using the deodorizer in any one of Claims 1-6 which reduces the complex odor originating in fatty acids, aldehydes, and amines. The deodorizing method using the deodorizer in any one of Claims 1-6 for textiles, for hard surfaces, or for space. The deodorizing method which makes the deodorizer in any one of Claims 1-6 adhere to a target object, and reduces the smell of a target object.