JP4981949B2 - Chemical solution injection system with buttock-enhanced syringe and automatic injection device - Google Patents

Description

  The present invention relates to a syringe suitable for performing injection at a high injection pressure using a drive mechanism such as an automatic injector.

  In various fields including medical use, a syringe is used for liquid injection or the like. Injection of a high-viscosity chemical solution such as a contrast agent requires a high pressure and is difficult or very troublesome to operate manually. Therefore, it is common to inject using a mechanical syringe drive mechanism such as an automatic injection device. FIG. 5 shows a state in which a syringe is attached to the automatic injection device, and the syringe outer cylinder 3 is attached and fixed to a cylinder holder 4 attached to an automatic injection device body 1 equipped with a motor and a control mechanism. Then, the piston holder 2 holding the syringe piston is advanced or retracted, and liquid is injected (discharged from the syringe) or suctioned. In order to hold the syringe outer cylinder, a hook is fitted into the groove of the cylinder holder and fixed.

  In the automatic injection device of FIG. 5, the piston drive mechanism and the calculation mechanism (including a display, a keyboard, etc.) are integrated. However, an automatic injection device in which the piston drive mechanism and the calculation mechanism are separated from each other is also known. Yes. FIG. 8 is a view showing an example of another housing portion including a piston drive mechanism of such an automatic injection device. In this apparatus, when the size of the syringe is small, the syringe outer cylinder 3 is attached to a removable adapter 4a (cylinder holder) and further attached to the automatic injection apparatus 1b. FIG. 9 shows a state where the syringe is attached to the automatic injection device.

  FIG. 10 ((a) top view, (b) side view seen from the rear, and (c) (b) X-X 'sectional view) are enlarged views of the adapter 4a. As shown in this figure, the adapter has a groove 5, and the syringe outer cylinder is held by fitting a flange 9 of the syringe outer cylinder into the groove 5.

  Moreover, when the size of a syringe is just fit, as shown in FIG. 11, the syringe outer cylinder 3 is directly attached to the automatic injection device, and the syringe outer cylinder is fixed by the clamp mechanism 4b (cylinder holder). FIG. 12 shows a state where the syringe is mounted on the automatic injection device. The clamp mechanism 4b also has a groove, and the syringe outer cylinder 9 is fitted into the groove to hold the syringe outer cylinder.

  As described above, in any case, in order to hold the syringe outer cylinder, it is simple to fit the rod into a groove such as a cylinder holder and fix it.

  However, since the force during injection / suction concentrates on the sputum, there was a case where it was damaged especially from the base part.

  Accordingly, an object of the present invention is to provide a syringe outer cylinder that is not easily damaged even when a liquid having a high viscosity is injected at a high pressure.

The present invention relates to the following matters.
1. A syringe having a syringe outer cylinder and a syringe piston slidably inserted into the syringe outer cylinder;
An auto-injector to which the syringe is attached, and an auto-injector having a cylinder holder with a groove for inserting a flange of the syringe outer cylinder in order to hold the syringe outer cylinder;
A chemical injection system comprising:
The outer cylinder of the syringe has a flange and a reinforcing rib provided on the rear surface of the flange and having a concentric reinforcing portion and a radial reinforcing portion , wherein the height of the concentric reinforcing portion of the reinforcing rib is the height of the flange. 0.2 to 3 times the thickness of
The chemical solution injection system, wherein the flange and the reinforcing rib are fixed together by being fitted into a groove of the cylinder holder.
2. 2. The chemical injection system according to 1 above, wherein the radial reinforcing portion is provided around the concentric reinforcing portion.
3. 3. The chemical solution injection system according to 1 or 2, wherein the radial reinforcing portion has a tapered shape whose height decreases toward the outside.
4). A syringe having a syringe outer cylinder and a syringe piston slidably inserted into the syringe outer cylinder;
An auto-injector to which the syringe is attached, and an auto-injector having a cylinder holder with a groove for inserting a flange of the syringe outer cylinder in order to hold the syringe outer cylinder;
A chemical injection system comprising:
The outer cylinder of the syringe has a first tub, a second tub, and a double tub having a reinforcing rib provided between the first tub and the second tub. system.
5. 5. The chemical solution injection system according to 4 above, wherein the reinforcing rib includes a concentric circular portion and a radial portion.
6). 6. The chemical solution injection system according to 4 or 5, wherein the double rod is fixed by being fitted into a groove of the cylinder holder.
7). 7. The chemical solution injection system according to any one of 1 to 6, which is used for injection of a contrast agent.
8). 7. The chemical solution injection system according to any one of the above 1 to 6, wherein the syringe is a prefilled syringe filled with a chemical solution.
9. 9. The chemical injection system according to 8 above, wherein the chemical is a contrast medium.
Furthermore, the present application discloses a syringe outer cylinder in which a reinforcing rib having a concentric reinforcing portion and a radial reinforcing portion is provided on the rear surface of the collar.

The present application further discloses a syringe barrel having a double fold.

Furthermore, the present application also discloses a syringe outer cylinder in which a thick portion is provided at the base portion of the front surface of the bag.

Furthermore, the present application also discloses a syringe outer cylinder in which a tapered reinforcing portion is provided on the front surface of the bag.

  As a result of earnestly examining the problem of the syringe being damaged, the present inventor has found that by providing the reinforcing structure as described above on the heel, the strength is improved, and even if the pressure is concentrated on the heel, it is not easily damaged. Is.

  ADVANTAGE OF THE INVENTION According to this invention, when inject | pouring a liquid with a high viscosity by a high pressure, the syringe outer cylinder which cannot be damaged easily can be provided.

It is a figure which shows one example of the syringe outer cylinder of this invention. (A) Side view (view from the back), (b) Side view (view from the side) It is a figure which shows one example of the syringe outer cylinder of this invention. (A) Side view (view from the back), (b) Side view (view from the side) It is a figure which shows one example of the syringe outer cylinder of this invention. (A) Side view (view from the back), (b) Side view (view from the side) It is a figure which shows one example of the syringe outer cylinder of this invention. (A) Side view (view from the back), (b) Side view (view from the side) It is a figure which shows one example of an automatic injection apparatus. It is a figure which shows a general syringe outer cylinder. It is a figure which shows one example from which a reinforcement rib differs. It is a figure which shows a mode that a syringe is mounted | worn with an automatic injection apparatus. It is a figure which shows the state which mounted | wore the automatic injection apparatus with the syringe. It is an enlarged view which shows the adapter (cylinder holder) which hold | maintains a syringe outer cylinder. It is a figure which shows a mode that a syringe is mounted | worn with an automatic injection apparatus. It is a figure which shows the state which mounted | wore the automatic injection apparatus with the syringe. It is a figure which shows typically a mode that the syringe outer cylinder (there is shape distortion in a cage | basket) is hold | maintained by the groove | channel. It is a figure which shows typically a mode that the syringe outer cylinder (what provided the reinforcement rib in the rear surface of the collar) is hold | maintained by the groove | channel.

FIG. 1 is an example of a syringe outer cylinder in which a reinforcing rib is provided on the rear surface of the bag. FIG. 1 (a) is a side view of the syringe outer cylinder viewed from the rear side, and FIG. It is the side view which looked at the syringe outer cylinder near. In addition, before and after the outer cylinder of the syringe, the syringe tip side is the front as defined in FIG. The reinforcing rib 10 includes concentric reinforcing portions 11 and radial reinforcing portions 12. In the example of this figure, the concentric reinforcing portion 11 has an inner peripheral surface that forms part of the inner wall of the syringe outer cylinder, and the thickness d is substantially equal to the thickness D of the syringe outer cylinder. The thickness d may be, for example, about 0.5 to 3 times the wall thickness D of the syringe outer cylinder, preferably about 0.5 to 2 times, and more preferably about 0.7 to 1.5 times. Further, the height h ₁ of the concentric reinforcing portion 11 can be set as appropriate depending on the necessary reinforcing strength. For example, the height H ₁ of the flange 9 is 0.2 to 3 times, preferably 0.4 to 2 times. Can be set to a degree.

Also, the radial reinforcing portion 12, the length p ₁ in the example of this figure is provided with about 1/2 of the width L of the flange 9, 1 / 4-1 / 1 in the width L of the flange, preferably It can select suitably from the range of 1/4-2/3. The width and number of the radial reinforcing portions 12 can also be appropriately set in consideration of necessary strength. In addition, as shown in this figure, if the tapered shape has a height that decreases toward the outside, it is preferable in terms of handling because it is difficult to get caught, but there is a problem from the viewpoint of reinforcement even if it is not tapered. Absent.

  FIG. 7 shows a different example of the reinforcing rib. In this example, a part of the radial reinforcing portion 12 similar to FIG. 1 is a double rib 13 for other reasons such as alignment. All the radial reinforcing portions may be doubled in this way, or the number of the radial reinforcing portions in a portion where a force is particularly easily applied may be increased or the width may be increased.

  FIG. 2 is an example of a syringe outer cylinder having a double fold, FIG. 2 (a) is a side view of the syringe outer cylinder seen from the rear side, and FIG. 2 (b) is a syringe near the buttock. It is the side view which looked at the outer cylinder from the side.

  The double kite consists of two kites 20a and 20b, and a reinforcing rib 21 is provided between them. In the example of this figure, the structure of the reinforcing rib 21 is composed of a concentric circular part and a radial part, and the structure is the same as the reinforcing rib of the example shown in FIG. 1 except that the radial part is not tapered. can do. However, the reinforcing rib in this embodiment is not limited to the structure of such an example, as long as it has a structure that connects and reinforces the double ribs.

  FIG. 3 is an example of a syringe outer cylinder provided with a thick portion at the base portion of the front surface of the heel, and FIG. 3A is a side view of the syringe outer cylinder as viewed from the rear side, and FIG. ) Is a side view of the syringe outer cylinder in the vicinity of the buttocks as seen from the side.

The thick portion 31 of the base portion is provided concentrically at the base of the heel 30. Radial length p ₃ of the thick portion is in this example provided at about 1/2 of the width L of the collar 30, for example, 1 / 4-3 / 4 of the width L of the flange, preferably 1 / It can select suitably from the range of 4-2 / 3. The thickness h ₃ of the thick portion 31 can be set as appropriate depending on the required reinforcing strength, but is, for example, about 0.2 to 2 times the thickness H of the flange 30, preferably 0.3 to 1. It can be set to about 0 times, more preferably about 0.3 to 0.8 times. Moreover, it is preferable that the corner | angular part of the thick part is cut like the example of this figure.

  FIG. 4 is an example of a syringe outer cylinder in which a tapered reinforcing portion is provided on the front surface of the heel, and FIG. 4 (a) is a side view of the syringe outer cylinder viewed from the rear side, and FIG. ) Is a side view of the syringe outer cylinder in the vicinity of the buttocks as viewed from the side (however, the left half is a sectional view).

In this example, the front surface portion of the flange 40 is a tapered reinforcing portion 41, and the end of the taper and the end of the flange coincide. In this example, a notch 42 that is not partially tapered is provided for alignment and other reasons, but this is not an essential part of the present invention. Further, the height h ₄ of the taper-shaped reinforcing portion 41 can be appropriately set depending on the necessary reinforcing strength, but for example, about 0.2 to 2 times the thickness H of the flange 40, preferably 0.3 to 1. About 0.0 times, more preferably about 0.3 to 0.8 times can be set.

  As the material of the syringe outer cylinder shown in the above examples, those that are normally distributed are used, and from the viewpoint of the strength of the wrinkles, for example, those made of resin such as polypropylene resin are preferable, and known methods such as injection molding methods are known. It can be easily manufactured by the method.

  Comparing the structure of the present invention with a structure in which the thickness of the ridge is simply increased, simply increasing the thickness of the ridge makes it possible to retain internal distortion during injection molding or to cause distortion in shape. . When the internal strain remains, the strength sufficient for the thickness is not developed. Further, when the shape distortion occurs, as schematically shown in FIG. 13, when the syringe piston is pushed, the position of the heel is not stabilized and the position shift occurs, and the pressure is concentrated only on a part of the heel. The situation where it breaks easily occurs. On the other hand, each reinforcing structure in the present invention can be configured with a thickness equivalent to the thickness of the conventional bag or the thickness of the syringe outer cylinder, and in that case, sufficient strength can be obtained without residual distortion. Also, the shape is stable.

  The manner in which the syringe outer cylinder of the present invention is held by a groove such as a syringe holder can be appropriately selected depending on its shape. For example, when the reinforcing member is a reinforcing rib as shown in FIG. 1, especially when a radial reinforcing portion (not necessarily tapered) is provided up to the peripheral portion, the reinforcing member is also a groove together. Can be fixed. FIG. 14 schematically shows how the groove is held. Such reinforcing ribs have improved shape accuracy compared to thick ridges, and as shown in this figure, they contact the rear surface of the groove in a relatively small area, so that the adhesion is better. Improved and can be mounted in the correct position. On the other hand, in the case of a cocoon that is simply thickened, the distortion of the rear plane is also greatly distorted.

  The syringe outer cylinder of the present invention can be used for various purposes such as liquid injection in combination with an ordinary piston. For example, it is preferably used for injection of medical chemicals, particularly for injection. It is preferably used for injecting a drug solution having a high viscosity such as a contrast agent requiring high pressure.

  Moreover, it is also preferable to use the syringe outer cylinder of the present invention for a prefilled syringe prefilled with a chemical solution such as a contrast medium.

DESCRIPTION OF SYMBOLS 1 Automatic injection apparatus main body 1b Automatic injection apparatus 2 Piston holder 3 Syringe outer cylinder 4 Cylinder holder 4a Adapter (cylinder holder)
4b Clamp mechanism (cylinder holder)
5 Groove 9 鍔 10 Reinforcement rib 11 Concentric reinforcement 12 Radial reinforcement 13 Double ribs 20a, 20b Double ridge 21 Reinforcement rib 30 鍔 31 Thick part 40 鍔 41 Tapered reinforcement

Claims (9)

A syringe having a syringe outer cylinder and a syringe piston slidably inserted into the syringe outer cylinder;
An auto-injector to which the syringe is attached, and an auto-injector having a cylinder holder with a groove for inserting a flange of the syringe outer cylinder in order to hold the syringe outer cylinder;
A chemical injection system comprising:
The outer cylinder of the syringe has a flange and a reinforcing rib provided on the rear surface of the flange and having a concentric reinforcing portion and a radial reinforcing portion , wherein the height of the concentric reinforcing portion of the reinforcing rib is the height of the flange. 0.2 to 3 times the thickness of
The chemical solution injection system, wherein the flange and the reinforcing rib are fixed together by being fitted into a groove of the cylinder holder.   The chemical injection system according to claim 1, wherein the radial reinforcing portion is provided around the concentric reinforcing portion.   The chemical solution injection system according to claim 1, wherein the radial reinforcing portion has a tapered shape whose height decreases toward the outside. A syringe having a syringe outer cylinder and a syringe piston slidably inserted into the syringe outer cylinder;
An auto-injector to which the syringe is attached, and an auto-injector having a cylinder holder with a groove for inserting a flange of the syringe outer cylinder in order to hold the syringe outer cylinder;
A chemical injection system comprising:
The outer cylinder of the syringe has a first tub, a second tub, and a double tub having a reinforcing rib provided between the first tub and the second tub. system.   The chemical solution injection system according to claim 4, wherein the reinforcing rib includes a concentric part and a radial part.   The chemical injection system according to claim 4 or 5, wherein the double rod is fitted and fixed in a groove of the cylinder holder.   The chemical solution injection system according to any one of claims 1 to 6, which is used for injection of a contrast agent.   The said syringe is a prefilled syringe with which the chemical | medical solution was filled, The chemical | medical solution injection system in any one of Claims 1-6 characterized by the above-mentioned.   9. The chemical solution injection system according to claim 8, wherein the chemical solution is a contrast agent.

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