JP4967183B2 - Blood collection device for arterial or venous line blood collection system, and arterial or venous line blood collection system using the blood collection device. - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a blood collection device for an arterial or venous line blood collection system, and an arterial or venous line blood collection system using the blood collection device.
[0002]
[Prior art]
Currently, blood collection using a three-way stopcock is the mainstream in the blood collection line. For example, in an operating room or an intensive care unit, an arterial measurement pressure line is not only used as a pressure monitor but also frequently used as an arterial line blood collection system using a three-way stopcock.
[0003]
[Problems to be solved by the invention]
However, although the blood collection system using the three-way stopcock has a high cost advantage, it has to be improved in terms of operability, safety and hygiene. First, regarding operability and safety, the blood collection system equipped with a three-way stopcock must switch the flow path by operating a plurality of three-way stopcock cocks during reverse blood flow, which is very complicated. There was also a great risk of misoperation. Also, as described below, there were many problems from the aspect of maintaining cleanliness. That is, when the fitting such as a syringe is removed from the three-way stopcock, blood (chemical solution) or the like remains in the recessed fitting portion of the three-way stopcock, and it is difficult to remove the residual blood or the like with alcohol cotton or the like. Moreover, since the fitting part of the three-way stopcock is open to the outside, if there is residual blood, it tends to be a hotbed for bacterial propagation.
[0004]
[Means for Solving the Problems]
In order to solve the above-mentioned problems, the present inventors have developed a new arterial line blood collection system and blood collection device, and have been able to solve the problems.
According to a first aspect of the present invention, there is provided a blood collection device for an arterial or venous line blood collection system characterized by comprising at least a pair of co-infusion ports having a structure that does not require switching of blood flow paths.
That is, the present invention is not a three-way stopcock that is normally used as a co-infusion member at present, but has at least a pair of co-infusion ports having a structure that does not require switching of the blood flow path. By using a blood collection device for a line blood collection system, the above problem could be solved.
[0005]
According to a second aspect of the present invention, the blood collection device for the first arterial or venous line blood collection system is characterized in that the mixed injection port has a structure satisfying at least the following constituents (1) to (3): It is in.
(1) A structure in which the blood conducting body and the flow path of the mixed injection portion (port) can be communicated / blocked without switching the flow path by inserting / removing the blood conducting body into / from the mixed injection port fitting portion,
(2) A structure capable of holding the blood conducting body (tip portion) of the tip portion having a non-sharp shape in the mixed injection port fitting portion in an inserted state.
(3) A structure in which the inside of the mixed injection portion is blocked from the outside world when the blood conducting body is removed.
The “non-sharp shape” means that the blood conducting body does not use a needle at its tip, and the tip of the blood conducting body has a shape that does not hurt the living body, for example, a rounded shape. It refers to things. A typical example of such a shape is a male luer taper defined by ISO 594-1.
As a structure that satisfies the requirements of (1), (2), and (3), for example, a luer part such as a tip of a needleless syringe is inserted, and the insert can be held by the fitting part, Further, there is a structure in which a disc valve that can be opened and closed by inserting / removing a blood conducting body is installed at the boundary between the inside and outside of the co-injection portion.
[0006]
According to a third aspect of the present invention, the mixed artery port satisfies the following configuration requirement (4) in addition to the requirements (1), (2) and (3): Or in a blood collection device for a venous line blood collection system.
(4) A structure that can easily remove the liquid adhering to the outer surface of the mixed injection port fitting portion.
[0007]
A fourth aspect of the present invention resides in the blood collection device for an arterial or venous line blood collection system according to the second or third aspect, wherein the structure of (3) is a disc valve in which an insertion hole is formed.
[0008]
As an example of a specific structure of a mixed injection port that satisfies the above-described requirements, a disc-shaped valve having an insertion hole formed in the central portion, and at least the upper peripheral edge of the valve leaving the central portion of the front side surface of the valve And a cover for holding the valve that covers the valve, and the cover has a locking means for locking the insert to the mixed injection port.
That is,
According to a fifth aspect of the present invention, the co-injection port holds the disc-shaped valve having an insertion hole formed in the central portion and the valve that covers at least the upper peripheral edge of the valve while leaving the central portion of the front surface of the valve. The blood collection device for the first to fourth arterial or venous line blood collection systems is characterized in that the cover is provided with a locking means for locking the insert to the mixed injection port.
As an example of the mixed injection port having such a structure, there is a mixed injection port (Japanese Patent Laid-Open No. 11-197254) previously developed by the present applicant.
[0009]
A sixth aspect of the present invention is the blood collection device for the arterial or venous line blood collection system according to any one of the first to fifth aspects, wherein the mixed injection ports are arranged in series via a conduit.
In the co-infusion port, by connecting a pair of co-infusion ports in series via a conduit, it is possible to collect blood that is less affected by dilution with a chemical solution and to improve operability. That is, a pair of co-infusion ports are arranged at an appropriate distance to facilitate treatment, and a clamp is attached to a conduit between the co-infusion ports to use the method as in Embodiment 2 described later. You can also.
[0010]
A seventh aspect of the present invention is the blood collection device for the sixth arterial or venous line blood collection system, wherein the distance of the conduit between the co-infusion ports is 20 to 50 mm. That is, the distance of the conduit | pipe between two mixed injection ports is 20-50 mm, More preferably, it is 30-40 mm. If it is shorter than the above range, it becomes impossible to attach the clamp to the conduit, the operability is lowered, and it is difficult to manufacture.
[0011]
The eighth of the present invention lies in the blood collection device for the first to seventh arterial or venous line blood collection systems configured by connecting a non-sharp syringe to the mixed injection port.
The “non-sharp” means the same thing as defined in the second.
[0012]
A ninth aspect of the present invention is the eighth arterial or venous line blood collection system, wherein the syringe is a needleless syringe.
[0013]
A tenth aspect of the present invention is an arterial or venous line blood collection system, wherein a blood collection device is the first to ninth blood collection devices.
[0014]
An eleventh aspect of the present invention is the tenth arterial or venous line blood collection system, wherein a predetermined amount is reversely blood (blood inhaled) from the upstream mixed injection port and blood is collected from the downstream mixed injection port.
The predetermined amount of reverse blood (blood inhalation) is influenced by the liquid filling amount of the flow path from the patient puncture portion to the downstream side co-infusion port, and is about 200 to 250% of the filling amount. In Embodiment 3 to be described later, a preferable reverse blood volume is about 0.8 ml in Embodiment 3 to be described later.
[0015]
In the arterial or venous line blood collection system of the present invention, the drug solution contained in the infusion / transfusion line from the puncture portion to the downstream co-infusion port or the blood diluted in the medicinal solution is sucked from the upstream side co-infusion port, diluted, etc. To eliminate the affected blood. After that, blood is aspirated and collected from the downstream side co-infusion port, so that blood in the same state as that in the patient's body can be simply converted from the infusion / transfusion line connected to the patient, in other words, diluted by the infusion / transfusion line. It is possible to collect blood with less influence.
[0016]
According to a twelfth aspect of the present invention, in the tenth or eleventh arterial line blood collecting system, the blood collecting device is incorporated in an arterial pressure line or a venous pressure line.
An example of the arterial pressure line is a Baxter monitor kit TC2601SC.
[0017]
The mixed injection port used as a blood collection device in the present invention is known from Japanese Patent Application Laid-Open No. 11-197254 as described above, and includes a disk-shaped valve having an insertion hole formed in the central portion, and the center of the front surface of the valve. The medical co-infusion port is characterized in that the cover includes a cover for holding the valve that covers at least the peripheral upper portion of the valve while leaving a portion, and has a locking means for locking the insert to the co-infusion port. .
An example of the medical co-infusion port is a cross-sectional structure as shown in FIG. However, the mixed injection port that can be used in the present invention is not limited to the one shown in FIG. 2, and the mixed injection port disclosed in the above-mentioned publication is limited within a range in which the object of the present invention can be achieved. Can be used without
[0018]
The pair of co-infusion ports constituting the blood collection device of the present invention can also be used for pumping of the infusion / transfusion line as shown in FIG.
That is, an infusion line (system) was configured using the pair of mixed injection ports on the patient side of the filter of the quantitative tube with filter.
The infusion line (system) is connected to the upstream mixed injection port by connecting a chemical supply line having a chemical container containing a chemical solution for infusion, and the downstream mixed injection port by inserting the end of a needleless syringe. Configured.
In the pumping of the system, after closing the gap between the filter of the metered cylinder with a filter and the upstream side co-injection port with an existing clamp or the like, the drug solution in the drug solution container is sucked into the syringe by the suction operation of the syringe. The drug solution is injected into a vein, for example, by a syringe.
In the system, it is necessary to provide one-way valves between the upstream and downstream mixed injection ports and downstream of the mixed injection ports.
[0019]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, the arterial and venous line blood sampling system of the present invention and the operation procedure thereof will be described in detail with reference to the drawings, taking as an example the case of using a monitor kit which is a commercially available arterial pressure line.
[0020]
Embodiment 1
This embodiment is an embodiment in which the reverse blood is not discarded by using the arterial line blood sampling kit of the present invention.
As shown in FIG. 3A, a monitor kit (Baxter monitor kit TC2601SC), which is a commercially available pressure line for measuring arteries, is a remaining portion (X portion) from which the patient side portion (Z portion) is removed from the extension tube. The blood collection device Y of the present invention shown in FIG.
As shown in FIG. 1, the blood collection device Y has two co-infusion ports, a co-infusion port A on the side opposite to the patient side (hereinafter also referred to as an upstream side) and a co-infusion port B on the patient side in series via a conduit. The conduit connected to the upstream side of the mixed injection port A has a connecting member C connected to the X portion, and the indwelling needle D is connected to the conduit connected to the downstream side of the mixed injection port B. Composed.
[0021]
Hereinafter, the operation procedure of this embodiment will be described with reference to FIG.
Step 1
The lure part at the tip of a needleless syringe for reverse blood is inserted into the insertion hole (E in FIG. 1) of the upstream mixed injection port A shown in FIG. It is appropriate to use 1 ml to 2.5 ml of the syringe at this time. Insert the co-injection port and the syringe all the way in and fit them securely. When strongly connected as described above, the mixed injection port has a structure that does not easily fall off with the syringe connected. With normal blood pressure, suction is possible simply by connecting a syringe. If the volume of the syringe is sucked, no further suction is performed by the stopper of the syringe. When the suction is sufficiently performed, the syringe is removed from the mixed injection port A. The amount of suction is adjusted according to the syringe size.
[0022]
Step 2
Next, as shown in FIG. 4 (b), the lure part at the tip of the needleless syringe for blood collection is similarly connected to the insertion hole (E in FIG. 1) of the patient side mixed injection port B, and blood pressure is used. Collect the necessary amount of blood. Although it is preferable if the suction that depends on the blood pressure can be performed, if the suction that depends on the blood pressure cannot be performed, the suction is slowly performed. Here, it is possible to perform the above operation without removing the reverse blood syringe, but if rapid blood collection is performed, physiological saline is drawn from the reverse blood syringe.
[0023]
Step 3
When the blood collection is completed, the blood collection syringe is removed from the mixed injection port B, and then the blood in the circuit is washed away using a flash device attached to the transducer.
When the reverse blood syringe is attached until this time, the blood in the syringe may be returned to the line as necessary. Finally, the used mixed injection port fitting portion is wiped with alcohol cotton or the like to remove the liquid adhering to the fitting portion and disinfect.
[0024]
Furthermore, an embodiment of a blood collection operation according to another operation procedure will be described with reference to FIG.
Embodiment 2
This embodiment is an embodiment of a method that does not discard the reverse blood.
As in the first embodiment, the mixed injection ports A and B are sufficiently disinfected before the blood collection operation.
In the same manner as in Embodiment 1, as shown in FIG. 5 (a), a needleless empty syringe for reverse blood is connected to the upstream side co-injection port A by inserting the luer portion at the end thereof, Aspirate. The size of the syringe at this time is preferably 1 ml to 2.5 ml as in the first embodiment.
The co-injection port A and the syringe can be strongly connected, and when they are strongly connected, the syringe is kept connected and does not easily fall off. And suction is possible only by connecting a syringe to the mixed injection port A with normal blood pressure.
If the volume of the syringe is sucked, no further suction is performed by the stopper of the syringe. Remove after sufficient suction. The amount of suction is adjusted according to the syringe size.
[0025]
Step 2
Next, clamp the tube between the co-infusion ports A and B, and connect the empty syringe without needle to the co-infusion port B by inserting the luer part at the end in the same way as in the procedure 1 above, and using the blood pressure, the necessary amount Collect blood. At this time, it is preferable that the blood pressure can be aspirated, but if not, it may be slowly aspirated.
Step 3
After the blood collection is completed and the syringe connected to the co-infusion port B is removed, the clamp that has been closed is opened, and the blood sucked into the syringe fitted in the co-infusion port A is returned to the line. Thereafter, the blood in the circuit is washed away using a flash device attached to the transducer.
Lastly, use the alcohol mixture to disinfect the joint port and syringe that were used last.
Although the operation procedure for the arterial line blood collection system has been described in the first and second embodiments, the same operation as that employed in the first and second embodiments using the blood collection system as shown in FIGS. Venous blood can be collected by the procedure.
[0026]
This embodiment is an embodiment of an example of the blood collection device of the present invention. In FIG. 1, mixed injection ports A and B are mixed injection ports composed of a disk-like valve having an insertion hole E which is a syringe connecting portion as shown in FIG. B is connected by a conduit made of vinyl chloride resin. The mixed injection port B is connected to the indwelling needle and the conduit, and the mixed injection port A is connected to the connecting member C and the conduit. A needleless type syringe is inserted into the insertion hole E of the mixed injection port A and B and connected. As described above, since the syringe is a needleless type syringe, there is no danger of needle stick in operation, and handling is easy.
[0027]
【effect】
(1) Blood can be collected by simply inserting a syringe without a needle into a co-infusion portion of an infusion / transfusion line connected to a patient. Thereby, it is not necessary to puncture the patient with the injection needle each time for the purpose of blood collection, and since the injection needle is not used when blood is collected from the co-injection portion, there is no danger of needle sticking and it is safe. In addition, since there is no flow path switching operation that is necessary with the conventional blood collection means, the blood collection procedure is simple and the risk of erroneous operation is reduced.
(2) There is little residual blood in the fitting portion of the mixed injection port, and even when residual blood is left, it is hygienic because it is easy to remove blood. A closed system is formed, which is excellent as a countermeasure against infection.
(3) The amount of reverse blood required for blood collection is small, and even if it is used for newborns, the influence on circulatory dynamics is minimal. Furthermore, if the reverse blood is returned to the line, there is no blood loss that occurs every time blood is collected.
(4) By using the blood collection system of the present invention and performing a predetermined amount of reverse blood, dilution of the blood is hardly observed, which is useful for clinical use. Further, by using the mixed injection port having the above-described structure, the amount of reverse blood can be reduced, which is more useful.
(5) The frequency characteristic of the line itself was kept good, and the cleanliness was also kept sufficiently.
(6) By using the mixed injection port, blood does not stay in the connecting portion as compared with the three-way stopcock.
[Brief description of the drawings]
FIG. 1 is a diagram showing an example of a blood collection device of the present invention.
FIG. 2 is a cross-sectional view of an example of a mixed injection port used in the present invention.
FIG. 3 is a diagram showing a monitor kit that is an arterial pressure line used in the embodiment, and an arterial line blood collection system in which the blood collection device of the present invention is incorporated in the monitor kit.
(A) Monitor kit that is an arterial measurement pressure line (b) Arterial line blood collection system incorporating a blood collection device FIG. 4 is a diagram showing an arterial line blood collection system according to Embodiment 1 of the present invention.
(A) It is a figure explaining operation of procedure 1.
(B) It is a figure explaining operation of procedure 2. FIG.
FIG. 5 is a diagram showing an arterial line blood collection system according to a second embodiment of the present invention.
(A) It is a figure explaining operation of procedure 1.
(B) It is a figure explaining operation of procedure 2. FIG.
FIG. 6 is a diagram in which a pair of co-infusion ports constituting the blood collection device of the present invention is used for an infusion line.
[Explanation of symbols]
1 Valve (disc valve)
2 Cover 6 Mating hole 7 Pedestal L1 Valve thickness L2 Mating hole thickness L3 Pedestal thickness L4 Pedestal hole diameter H Mixed injection port height X Z is a commercially available pressure line for measuring arteries. Remaining part Y of the monitor kit Blood collection device Z Part A which is removed from the monitor kit which is a pressure line for arterial measurement and connected to Y A Mixed injection port B Mixed injection port C Connecting member D Indwelling needle (connection part)
E Disc-shaped valve insertion hole of the mixed injection port (syringe connection part)
F Infusion container
G needleless syringe
H One-way valve

Claims (6)

In a blood collection device for an arterial line blood collection system in which a mixed injection port having a structure satisfying the following requirements (1) to (4) is arranged, a pair of mixed injection ports connected in series by a conduit and the pair of mixed injection ports The clamp has a clamp disposed in the conduit between the mixed injection ports, and the upstream mixed injection port of the pair of mixed injection ports is used for reverse blood (blood inhalation) using a non-sharp blood conductor. The blood collection device for an arterial line blood collection system is characterized in that a downstream mixed injection port of the pair of mixed injection ports is used for blood collection using a non-sharp blood conducting body.
(1) It has a flow passage and a non-sharp blood conducting body fitting portion.
(2) The distal end portion of the blood conducting body can be held in an inserted state in the fitting portion.
(3) The blood conducting body and the flow path can be communicated and blocked by insertion / removal of the blood conducting body from the fitting portion.
(4) The inside of the mixed injection port can be blocked from the outside when the blood conducting body is removed. The mixed injection port includes a disc-like valve having an insertion hole formed in the center portion, and a cover that holds the valve covering at least the upper peripheral edge of the valve while leaving the center portion of the front surface of the valve. The blood collection device for an arterial line blood collection system according to claim 1 , wherein the cover has a locking means for locking to a mixed injection port. The blood collection device for an arterial line blood collection system according to claim 1 or 2, wherein the distance of the conduit between the adjacent mixed injection ports is 20 to 50 mm. The blood collection device for an arterial line blood collection system according to any one of claims 1 to 3, wherein the blood conducting body having a non-sharp tip is a syringe having a non-sharp tip. The blood collection device for an arterial line blood collection system according to claim 4, wherein the syringe is a needleless syringe. An arterial pressure measurement pressure line, wherein the arterial line blood collection system blood collection device according to any one of claims 1 to 5 is incorporated.

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