JP4943728B2 - Blood glucose meter - Google Patents

Description

  The present invention relates to a blood glucose meter.

  Treatment of diabetes using insulin is often carried out by patients on a daily basis, such as using different preparations depending on the symptoms. However, if a wrong drug is used, life may be threatened.

  In patients with insulin deficiency, called type 1 diabetes, or severe type 2 diabetes, where insulin is unstable, the patient administers an appropriate insulin preparation according to the blood glucose level while self-measuring the blood glucose level Treatment is recommended. These patients self-inject intermediate or continuous insulin preparations that correspond to basal secretions once or twice a day, or self-measure blood glucose levels before each meal and then inject rapid-acting preparations. . Alternatively, mixed insulin in which intermediate type and fast acting type are mixed at a constant ratio may be used. However, if the type and dose of an insulin preparation are wrong, insulin will be excessive even though the blood glucose level is low, and if it is severe, seizures and coma will occur.

  In order to prevent such administration mistakes, a label with electrically readable information is affixed to the outer surface of the cartridge containing insulin, and the type, amount, expiration date, etc. of the drug are displayed as this information. (See Patent Document 1). However, the information displayed on such a label has problems such as being unreadable when the surface becomes dirty or damaged, and the amount of information is limited.

  In addition, in order to completely control the blood glucose of the patient, a device for predicting the blood glucose level of the patient after a certain time based on the blood glucose level detected by the blood glucose meter, determining the insulin dosage, and administering insulin is proposed. (See Patent Document 2).

This device is disclosed from a 24-hour human body connection device that performs blood glucose measurement and insulin administration to a device that uses separate measuring devices and injectors. It is not intended to prevent the mixing of chemicals in devices that can be used in the future.
JP-T-2004-505701 JP 2003-79723 A

  Thus, conventionally, based on the blood glucose level at the time of administration, the type and dosage of the drug to be administered are determined based on the prescription data, and it is determined whether or not the drug loaded in the injector is an appropriate type. And could not issue warnings when inappropriate.

  The present invention determines the type and dosage of a drug to be administered based on prescription data based on the blood glucose level at the time of administration so that safe treatment can be performed according to the patient's situation, and is loaded into an injector. An object of the present invention is to provide a blood glucose meter capable of determining whether or not a given medicine is an appropriate type and issuing a warning when it is inappropriate.

In order to solve the above problems, the present invention provides a blood glucose level measuring means for measuring a blood glucose level in blood collected from a patient, and the type and dose of insulin to be administered to the patient. Storage means for storing the blood glucose level in association with the time zone when the blood glucose level was obtained, and the storage means in association with the blood glucose level obtained by the measurement in the time zone measured by the blood glucose level measurement means. A determination means for determining a stored insulin type and dosage; an output means for outputting the determined insulin type and dosage by at least one of a screen display and a voice; and the patient uses A communication means provided in an insulin cartridge loaded in the insulin injector and communicating with an IC tag for holding information relating to the insulin cartridge; From the information about the insulin cartridge acquired from the group, it is determined whether the specifying means for specifying the type of insulin in the insulin cartridge matches the specified type of insulin and the determined type of insulin. A determination means that, when the specified insulin type and the determined insulin type do not match, the output means warns that the insulin cartridge loaded in the insulin injector is not appropriate. Is output by at least one of screen display and sound , and the insulin cartridge is packaged with a conductive film in an unused state .

  In addition, the present invention for solving the above-described problems further includes an insulin loaded in the insulin injector when the output means matches the identified insulin type with the determined insulin type. The fact that the cartridge is appropriate is output by at least one of screen display and sound.

According to the present invention, based on the blood glucose level at the time of administration, the type and dose of the drug to be administered are determined based on the prescription data, and it is determined whether or not the drug loaded in the injector is an appropriate type Thus, it is possible to provide a blood glucose meter capable of issuing a warning when inappropriate. Further, since the unused insulin cartridge is packaged with a conductive film, it is possible to avoid interference with the IC tag attached to the unused cartridge.

  Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.

  FIG. 1 is a diagram showing a configuration example of a system including an insulin syringe and a blood glucose meter corresponding to the present invention. The system configuration shown in FIG. 1 is simply shown as an example to the last, and the system configuration is not limited to this. For example, the blood glucose meter can be connected to an external server and can communicate. Moreover, it is good also as a system which integrated the insulin syringe and the blood glucose meter.

  In FIG. 1, the insulin injector 100 can be loaded with an insulin cartridge 101. The insulin injector 100 injects insulin contained in the insulin cartridge 101 into the patient's body from the injection needle 105 by the number of units set by the unit setting unit 103 based on the operation of the operation unit 104. The insulin cartridge refers to an insulin-filled cartridge that is used by being mounted on the insulin syringe 100, as well as an integrated syringe prefilled with a syringe vial and insulin.

  An IC tag 102 is attached to the insulin cartridge 101. In the IC tag 102, information related to insulin contained in the insulin cartridge 101 is registered.

  In general, there are five types of insulin, a super fast-acting type, a fast-acting type (R), an intermediate type (N), a continuous type, and a mixed type thereof (such as 10R). The super fast-acting type shows an effect 10 to 20 minutes after subcutaneous injection and has a short action duration of 3 to 5 hours. The fast-acting type shows an effect about 30 minutes after subcutaneous injection, and the duration of action is about 8 hours. The intermediate type or continuous type has a duration of action of 12 to 24 hours and is used to compensate for basal insulin secretion. The mixed type is a mixture of fast-acting (or super-fast-acting) and intermediate-type insulin, which has both effects. For example, 10R, 20R, 30R, 40R, and 50R depending on the ratio of fast-acting and intermediate-type. Etc.

  That is, the IC tag 102 holds at least the above insulin type, and includes the serial number of the insulin cartridge 101, the manufacturer name, and the like. The IC tag 102 also communicates with the blood glucose meter 110 to notify the insulin type contained in the insulin cartridge 101.

  Next, the blood glucose meter 110 includes a control unit 111 that controls the overall operation of the apparatus. Control in the control unit is performed according to a control program stored in the memory 112. The control unit 111 has an internal clock, and can manage a time period during which the blood sugar level is measured based on the internal clock. The memory 112 stores a processing program corresponding to the present embodiment. The communication unit 113 can communicate with the IC tag 102 to acquire information on the insulin type of the insulin cartridge 101.

  The display unit 114 is configured by a liquid crystal display, for example. The display 114 can display an appropriate insulin type and the number of units on the screen based on the blood glucose level measured by the blood glucose level measurement unit 116. Further, based on the insulin type acquired by the communication unit 113, the patient can be notified by displaying whether or not the insulin cartridge 101 loaded in the insulin injector 100 is an appropriate cartridge.

  The voice output unit 115 can notify the appropriate insulin type and the number of units by voice based on the blood sugar level measured by the blood sugar level measuring unit 116. Further, based on the insulin type acquired by the communication unit 113, it can be notified by voice whether or not the insulin cartridge 101 loaded in the insulin injector 100 is appropriate.

  The blood sugar level measuring unit 116 measures the blood sugar level in the blood of the patient. Blood glucose levels can be measured either continuously by collecting a blood sample and reacting with a reagent to measure blood glucose levels, or by measuring non-invasively from bodily fluids by continuously inserting a biosensor into the body. It can be either a formula.

  The prescription data table 117 is a table for managing patient prescription data of the blood glucose meter 110, and is used to determine an appropriate insulin type and the number of units based on the measured blood glucose level and the measurement time zone. The operation unit 117 includes buttons and the like for the patient to operate the blood glucose meter 110.

  Next, the configuration of the IC tag 102 corresponding to this embodiment will be described with reference to FIG. The configuration of the IC tag 102 shown in FIG. 2 is simply shown as an example only, and the chip configuration of the IC chip in the present invention is not limited to that shown in FIG.

  In FIG. 2, the IC tag 102 is largely composed of an antenna 201 and an IC chip 202. The IC chip 202 includes an RF unit 203, a control unit 204, and a storage unit 205.

The IC tag 102 is preferably an electromagnetic induction method that is not affected by water and is a small passive type. Although it may be attached directly to the insulin cartridge 101, it is more preferable that it is incorporated in a label. In order to avoid interference with an IC tag attached to an unused cartridge, the unused cartridge is packaged with a conductive film . Similarly, in order to avoid interference from the used cartridge, it is preferable to prepare a waste bag made of a conductive film, or to easily peel and discard the label.

  The RF unit 203 is for controlling wireless communication, and includes a transmitter and a receiver. The transmitter and receiver need only be those normally used in IC tags. In brief, the transmitter includes a modulator, a filter, and an amplifier, modulates the digital signal, removes unnecessary components by the filter, amplifies the amplified signal, and radiates from the antenna 201. The receiver includes an amplifier, a demodulator, and a filter. The antenna 201 receives a signal propagated through space, and extracts a necessary band by the filter. Further, the receiver amplifies this with an amplifier and performs frequency conversion with the decoder to decode the signal.

  As a frequency used for communication, for example, any of 13.56 MHz, 2.45 GHz, and 860 to 960 MHz can be used. The communicable distance is, for example, about 50 cm or less at 13.56 MHz and about 100 cm or less at 2.45 GHz. The frequency to be used can be appropriately selected according to the situation when the blood glucose meter 110 and the insulin injector 100 are used.

  The control unit 204 reads out information related to the insulin cartridge 101 stored in the storage unit 205 based on an instruction from the blood glucose meter 110 of the IC tag 102 and transfers the information to the RF unit 203.

  The storage unit 205 stores information regarding the insulin cartridge 101. Specifically, the type of insulin contained in the insulin cartridge 101 (insulin type), the serial number of the cartridge, the manufacturer name, the expiration date, etc. are stored.

  Next, an example of the configuration of the IC tag 102 corresponding to the present embodiment is shown with reference to FIG. The configuration of the IC tag 102 illustrated in FIG. 3 is simply illustrated as an example, and the tag configuration is not limited thereto.

  In FIG. 3, an IC chip 202 including an RF unit 203, a control unit 204, and a storage unit 205 of the IC tag 102 is disposed on a flexible sheet 302. The sheet 302 may be any material that can withstand heat during sterilization of the insulin cartridge 101, and various olefin resins such as polypropylene, nylon, polyester, polyimide, and the like are suitable.

  On the sheet 302, an antenna pattern 303 that functions as the antenna 201 is printed. The antenna pattern 303 is formed of a metal foil such as copper, metal deposition or printing, or a thin coil having a thickness of several tens of microns.

  As described above, the IC tag 102 is preferably configured as an inlet 300 having a hybrid structure in which the chip 202 on which the semiconductor circuit is formed is mounted on the sheet 302 on which the antenna pattern 303 is formed.

  Next, an example of the data structure of the prescription data table 117 will be described with reference to FIG. Note that the data structure of the prescription data table shown in FIG. 4 is simply shown as an example, and the contents of the prescription data in the present invention are not limited to those shown in FIG. The prescription data table is different for each patient who uses the insulin injector 100 and the blood glucose meter 110, and even for the same patient, the prescription data table is appropriately changed according to the symptoms. Accordingly, a prescription data table is appropriately configured according to such changes or according to patients, and processing corresponding to the present invention is performed.

  Usually, insulin is divided into four times before morning, noon, evening and before going to bed. Therefore, in the prescription data table 117, prescription data is managed by separating one day into four time zones as “morning”, “noon”, “night”, and “before going to bed” as the time zone 401. Here, “morning” refers to, for example, a time zone from 6 am to immediately before 12:00 pm, and “daytime” refers to, for example, a time zone from 12:00 pm to immediately before 5 pm, "" Refers to, for example, a time period from 5:00 pm to immediately before 9:00 pm, and "before going to bed" can be considered to indicate, for example, a time period from 9:00 pm to 2:00 am. About the setting of the time slot | zone 401, it can set suitably according to a patient's life pattern.

  Next, the blood sugar level range 402 defines a range in which the blood sugar level measured by the blood sugar level measuring unit 116 is included. In the present embodiment, the range of blood glucose levels is roughly divided into four categories: “less than 100”, “100 or more and less than 150”, “150 or more and less than 200”, and “200 or more”. The unit of blood glucose level is usually expressed as “mg / dl”, but the unit is omitted in FIG. 4 for simplicity.

  Insulin type 403 registers the type of insulin to be used based on time zone 401. For example, if “morning”, “daytime”, and “night” before each meal, “R”, that is, a fast-acting type is selected as the insulin type 403. If it is “before going to bed”, “N”, that is, an intermediate type is selected as the insulin type 403.

  In the unit number 404, the number of units to be administered for the selected insulin type 403 is registered. The dose of insulin is generally expressed using “unit”. For example, when the blood glucose level is “less than 100” in “morning”, “R”, that is, fast-acting insulin is administered as “6 units”. Will be.

  Next, the process performed between the insulin injector 100 and the blood glucose meter 110 corresponding to this embodiment will be described. First, FIG. 5 is an example of a flowchart of processing corresponding to the present embodiment. 5 is performed by the control unit 111 executing the processing program stored in the memory 112 and controlling the operation of the blood glucose meter 110.

  In FIG. 5, in step S <b> 501, for example, blood is collected on a test paper based on the operation of the operation unit 118, and the blood glucose level measurement unit 116 performs blood glucose level measurement. Note that the time period during which the measurement is performed is determined based on the internal clock of the control unit 111. Next, in step S502, the prescription data table 117 is searched based on the blood glucose level and time zone obtained in step S501, and the insulin type 403 and the number of units 404 to be used are determined as prescription data.

  Next, in step S <b> 503, the insulin type 403 and the unit number 404 determined as prescription data are displayed on the display unit 114 and also output from the audio output unit 115. A display example on the display unit 114 at this time is shown in FIG. As shown in FIG. 6, the blood sugar level and time zone measured in step S501 are displayed. Further, the insulin type and the number of units determined in step S502 are respectively displayed. By outputting the same content by voice output by the voice output unit 115, it is possible to notify the insulin type and the number of units to be accurately used to a patient whose display content is difficult to visually confirm.

  If the measured blood glucose level deviates significantly compared to the prescription data, for example, in the case of hypoglycemia, warning information such as “Danger, take urgent sugar” is displayed and notified by voice. May be.

  In the present embodiment, communication is performed when the IC tag 102 enters a communication area with the communication unit 113 of the blood glucose meter 110. Therefore, in step S504, it is determined whether communication with the IC tag 102 attached to the insulin cartridge 101 loaded in the insulin injector 100 has been established. If communication is established (“YES” in step S504), the process proceeds to step S505, and the IC tag 102 is requested to transmit information related to the insulin cartridge 101. Thereafter, in step S509, it is monitored whether or not information related to the request is received from the IC tag 102.

  On the other hand, on the IC tag 102 side, in step S506, it is determined whether or not communication with the blood glucose meter 110 has been established. If communication is established (“YES” in step S506), the process proceeds to step S507. In step S507, it is determined whether a request for information regarding the insulin cartridge 101 has been received from the blood glucose meter 110. If there is an information request (“YES” in step S507), the process proceeds to step S508. In step S508, the control unit 204 reads information including the insulin type from the storage unit 205, and transmits the information to the blood glucose meter 110 via the RF unit 203.

  The blood glucose meter 110 that has monitored the reception of information in step S509 proceeds to step S510 when the information is received (“YES” in step S509). In step S510, it is determined whether or not the insulin type included in the received information matches the insulin type determined in step S502.

  If the insulin types do not match (“NO” in step S510), the process proceeds to step S511. On the other hand, if the insulin types match (“YES” in step S510), the process proceeds to step S512.

  In step S511, the patient is notified that the type of insulin to be used is different by screen display on the display unit 114 and voice output by the voice output unit 115. A display example at this time is as shown in FIG. Here, a warning message “Insulin type to be used is different!” Is displayed, and the insulin type to be originally used and the number of units are displayed. The same content is output as audio by the audio output unit 115, so that the insulin cartridge 101 currently loaded in the insulin injector 100 is inappropriate for a patient whose display content is difficult to visually confirm. Can be notified.

  After the error display is performed in step S511, the insulin cartridge 101 is replaced. Therefore, the process returns to step S504 and attempts to establish communication with the IC tag 102 of the newly loaded insulin cartridge 101.

  In step S512, the patient is notified that the insulin cartridge 101 currently loaded in the insulin infusion device 100 is appropriate by screen display on the display unit 114 and audio output by the audio output unit 115. A display example at this time is as shown in FIG. Here, the message “Insulin type is appropriate. Use 14 units” is displayed, and the number of units to be administered is notified again. By outputting the same content by the voice output unit 115, it is possible to notify a patient who is difficult to visually confirm the display content.

  As described above, according to this embodiment, prescription data for each patient who uses the blood glucose meter 110 and the insulin injector 100 is managed in the blood glucose meter, and the insulin to be applied based on the measured blood glucose level The patient can be notified of type and dose (number of units). Further, it is determined whether or not the type of the insulin cartridge 101 loaded in the insulin injector 100 matches the prescription data, and if it is an inappropriate insulin type, an error is notified and a correct insulin type is notified. be able to.

  If an IC tag 102 is attached to each insulin cartridge 101, an appropriate cartridge can be found by communication with the blood glucose meter 110 without visually checking the contents of the insulin cartridge 101. Therefore, even a patient with visual impairment can select an appropriate insulin type and administer insulin.

  As described above, according to the present invention, it is possible to provide an information system in which a diabetic patient who self-treats with an insulin injector does not mistake the type and dose of insulin to be administered. In particular, it is possible to prevent medication errors due to misreading of drug labels of patients who are blind due to diabetic retinopathy.

It is a figure which shows the structural example of the system which consists of an insulin syringe and a blood glucose meter corresponding to embodiment of this invention. It is a figure which shows an example of a structure of the IC tag corresponding to embodiment of this invention. It is a figure which shows an example of a structure of the inlet type IC tag corresponding to embodiment of this invention. It is a figure which shows an example of the data structure of the prescription data table corresponding to embodiment of this invention. It is a flowchart which shows an example of the process corresponding to embodiment of this invention. It is a figure which shows an example of the display screen corresponding to embodiment of this invention. It is a figure which shows another example of the display screen corresponding to embodiment of this invention. It is a figure which shows another example of the display screen corresponding to embodiment of this invention.

Claims (2)

Blood glucose level measuring means for measuring blood glucose level in blood collected from a patient;
Storage means for storing the type and dose of insulin to be administered to the patient in association with the blood glucose level of the patient and the time zone when the blood glucose level was obtained;
Determining means for determining the type and dose of insulin stored in the storage means in association with the blood glucose level obtained by the measurement in the time zone when the blood glucose level measuring means was measured;
Output means for outputting the determined type and dose of insulin by at least one of screen display and sound;
A communication means provided in an insulin cartridge loaded in an insulin infuser used by the patient and communicating with an IC tag that holds information about the insulin cartridge;
Identification means for identifying the type of insulin in the insulin cartridge from the information about the insulin cartridge acquired from the IC tag;
Determination means for determining whether or not the specified type of insulin and the determined type of insulin match,
The output means displays a warning that the insulin cartridge loaded in the insulin injector is not appropriate when the specified insulin type does not match the determined insulin type, on a screen display and a voice. Output by at least one of the following:
The blood glucose meter, wherein the insulin cartridge is packaged with a conductive film in an unused state .   When the specified insulin type matches the determined insulin type, the output means indicates that the insulin cartridge loaded in the insulin injector is appropriate, at least on screen display and audio. The blood glucose meter according to claim 1, wherein the blood glucose meter is output by any one of them.

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