JP4730804B2 - 方法 - Google Patents

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Publication number
JP4730804B2
JP4730804B2 JP2001558013A JP2001558013A JP4730804B2 JP 4730804 B2 JP4730804 B2 JP 4730804B2 JP 2001558013 A JP2001558013 A JP 2001558013A JP 2001558013 A JP2001558013 A JP 2001558013A JP 4730804 B2 JP4730804 B2 JP 4730804B2
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JP
Japan
Prior art keywords
protein
array
proteins
antibody
tag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2001558013A
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English (en)
Japanese (ja)
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JP2003521922A5 (enExample
JP2003521922A (ja
Inventor
ブラックバーン、ジョナサン・マイケル
サザーランド、ジョン・デビッド
サマダー、ミタリ
マルダー、ミッチェル・アンネ
コズロースキー、ローランド・ゼット
Original Assignee
センス・プロテオミック・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0002215A external-priority patent/GB0002215D0/en
Priority claimed from GB0019888A external-priority patent/GB0019888D0/en
Application filed by センス・プロテオミック・リミテッド filed Critical センス・プロテオミック・リミテッド
Priority claimed from PCT/GB2001/000395 external-priority patent/WO2001057198A2/en
Publication of JP2003521922A publication Critical patent/JP2003521922A/ja
Publication of JP2003521922A5 publication Critical patent/JP2003521922A5/ja
Application granted granted Critical
Publication of JP4730804B2 publication Critical patent/JP4730804B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2001558013A 2000-01-31 2001-01-31 方法 Expired - Lifetime JP4730804B2 (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB0002215.2 2000-01-31
GB0002215A GB0002215D0 (en) 2000-01-31 2000-01-31 Method
GB0002515.2 2000-01-31
US19649000P 2000-04-12 2000-04-12
US60/196,490 2000-04-12
GB0019888A GB0019888D0 (en) 2000-08-11 2000-08-11 Method
GB0019888.7 2000-08-11
PCT/GB2001/000395 WO2001057198A2 (en) 2000-01-31 2001-01-31 Methods of generating protein expression arrays and the use thereof in rapid screening

Publications (3)

Publication Number Publication Date
JP2003521922A JP2003521922A (ja) 2003-07-22
JP2003521922A5 JP2003521922A5 (enExample) 2008-03-21
JP4730804B2 true JP4730804B2 (ja) 2011-07-20

Family

ID=26243526

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001558013A Expired - Lifetime JP4730804B2 (ja) 2000-01-31 2001-01-31 方法

Country Status (3)

Country Link
JP (1) JP4730804B2 (enExample)
DE (1) DE60142765D1 (enExample)
GB (1) GB2361698B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1742062A3 (en) 2001-12-05 2008-09-10 Sense Proteomic Limited Protein arrays for allelic variants and uses thereof
EP4448757A1 (en) * 2021-12-17 2024-10-23 ABSCI Corporation Solid-phase screening for high-performing bacterial strains

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999039210A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
WO2000004382A1 (en) * 1998-07-14 2000-01-27 Zyomyx, Inc. Arrays of proteins and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652128A (en) * 1993-01-05 1997-07-29 Jarvik; Jonathan Wallace Method for producing tagged genes, transcripts, and proteins
EP1003853B1 (en) * 1997-09-03 2005-11-30 Biovation Limited Methods for protein screening
CA2323638A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays
AU778194B2 (en) * 1999-07-12 2004-11-18 Bristol-Myers Squibb Company C-terminal protein tagging

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999039210A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
WO2000004382A1 (en) * 1998-07-14 2000-01-27 Zyomyx, Inc. Arrays of proteins and methods of use thereof

Also Published As

Publication number Publication date
GB0102454D0 (en) 2001-03-14
JP2003521922A (ja) 2003-07-22
GB2361698A (en) 2001-10-31
DE60142765D1 (de) 2010-09-23
GB2361698B (en) 2003-06-25

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