JP4515037B2 - Chemical solution injection method and chemical solution injection device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a chemical solution injection method and a chemical solution injection device for injecting a chemical solution into a subject, and particularly to a chemical solution injection method and a chemical solution injection device for injecting a contrast medium and physiological saline as a chemical solution.
[0002]
[Prior art]
Conventionally, as a fluoroscopic imaging apparatus that captures a tomographic image that is a fluoroscopic image of a subject, there are a CT (Computed Tomography) scanner, an MRI (Magnetic Resonance Imaging) apparatus, a PET (Positron Emission Tomography) apparatus, and the like. As medical devices for capturing a blood vessel image, an angio device, an MRA (MR Angio) device, and the like are known.
[0003]
When using this type of device, a chemical solution such as a contrast medium or physiological saline may be injected into a subject, and a chemical solution injection device that automatically executes this injection operation has been put into practical use. As such a chemical solution injection device, for example, a device having a drive motor and a slider mechanism to which a chemical solution syringe is detachably mounted is disclosed (for example, see Patent Documents 1 and 2).
[0004]
By the way, in PET examination, for example, fluorodeoxyglucose (FDG), which is a positron nuclide that emits a very small amount of radiation, is used as a contrast agent. For this reason, in the PET examination, radiation of about 2 to 3 mSv (milli-sievert) equivalent to radiation received from the natural world in one year in daily life is received.
[0005]
[Patent Document 1]
Japanese Unexamined Patent Publication No. 2002-11096 (2nd to 3rd pages, FIGS. 11 to 14)
[Patent Document 2]
JP 2002-102343 A (2nd page-3rd item, FIG. 8)
[0006]
[Problems to be solved by the invention]
In the above-described conventional PET examination, a doctor often manually operates a drug solution syringe and intravenously injects a contrast medium into a subject, and the contrast medium is contained in the drug solution syringe or a tube connected to the drug solution syringe. There is a problem that it remains.
[0007]
For this reason, doctors are exposed in the same manner as the subject when handling chemical syringes and tubes, and it is required to minimize the amount of exposure by doctors.
[0008]
In addition, the conventional chemical solution injection method has a disadvantage that the entire amount of the relatively expensive contrast agent is not injected.
[0009]
Therefore, the present invention reliably prevents the first chemical solution from remaining in the first chemical solution syringe or the tube, reliably injects the entire amount of the first chemical solution into the subject, and suppresses the radiation exposure of the doctor. It is an object of the present invention to provide a chemical solution injection method and a chemical solution injection device that can perform the same.
[0010]
[Means for Solving the Problems]
In order to achieve the above-described object, a chemical liquid injection device according to the present invention includes a first chemical liquid syringe filled with a first chemical liquid, a second chemical liquid syringe filled with a second chemical liquid, A tube for injecting the second drug solution into the subject, a first state in which the first drug solution syringe is communicated to the subject side through the tube, and a second state in which the second drug solution syringe is communicated to the subject side A switching means for switching to a third state in which the first chemical liquid syringe and the second chemical liquid syringe are communicated with each other, and switching the switching means to the first state to transfer the chemical liquid in the first chemical liquid syringe to the subject. The first operation for injecting the liquid into the first state, the switching means to the third state, the second operation for transferring the second chemical liquid from the second chemical liquid syringe to the first chemical liquid syringe, and the switching means to the first state Switch to the first chemical solution In the mode having the third operation for injecting the chemical liquid in the range into the subject, and the fourth operation for switching the switching means to the second state and injecting the chemical liquid in the second chemical syringe to the subject in this order. Control means for controlling the injection operation .
[0011]
According to the liquid injector according to the present invention described above, in the second operation, that the second chemical liquid is transferred to the first chemical solution in the syringe, the first chemical liquid remaining in the first chemical solution in the syringe Is mixed into the second chemical solution and then injected into the subject in a third action . Then, in the third operation, the second chemical liquid is injected from the second chemical liquid syringe into the subject, whereby the first chemical liquid remaining in the tube is injected into the subject. Therefore, according to the liquid injector of the present invention, without leaving the first chemical solution to the first chemical solution in the syringe and the tube, the total amount of the first chemical solution filled in the first chemical solution in the syringe is subject Injected into.
[0012]
Moreover, in the chemical injection device according to the present invention, the control unit may selectively control the above-described mode and another mode in which the fourth operation is performed after the first operation.
[0014]
Moreover, the imaging device according to the present invention includes the above-described chemical liquid injector of the present invention and captures a fluoroscopic image of a subject.
[0015]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, specific embodiments of the present invention will be described with reference to the drawings.
[0016]
The chemical injection device of the present embodiment is used to inject a contrast medium and physiological saline into a subject when performing a PET (Positron Emission Tomography) examination. As a contrast agent, fluorodeoxyglucose (FDG) is used.
[0017]
As shown in FIG. 1 and FIG. 2, the chemical liquid injector 1 includes a first head 6 for injecting a contrast agent, a second head 7 for injecting physiological saline, And an infusion part 8 constituting each infusion path for injecting a contrast medium and physiological saline into the subject from the second head parts 6 and 7.
[0018]
Further, as shown in FIG. 3, the chemical injection device 1 includes a control circuit unit 9 that controls the first and second head units 6 and 7, and an operation unit 10 for performing various operations. .
[0019]
As shown in FIGS. 1 and 3, the first head unit 6 includes a first syringe 11 filled with a contrast agent, and a first operation mechanism 13 for automatically operating the first syringe 11. And a syringe holder 15 for holding the first syringe 11.
[0020]
The first operating mechanism 13 includes a drive shaft 16a that drives the piston 11a of the first syringe 11, a motor 17a that rotationally drives the drive shaft 16a, and an encoder 18a that encodes the rotation of the motor 17a. is doing. The drive shaft 16a is provided in parallel with the moving direction of the piston 11a, and a pressing plate 19a that presses the piston 11a is engaged therewith.
[0021]
As shown in FIGS. 4 and 5, the syringe holder 15 is formed in a substantially cylindrical shape with tungsten or the like, for example, and the first syringe 11 is held on the inner peripheral portion. A handle 15 a for gripping is integrally provided on the outer peripheral portion of the syringe holder 15.
[0022]
A front cover member 26 and a rear cover member 27 that cover the front end side and the rear end side of the first syringe 11 are detachably attached to the syringe holder 15. The front cover member 26 and the rear cover member 27 are formed in a bottomed cylindrical shape with tungsten or the like, for example, and block radiation from the contrast agent filled in the first syringe 11. In addition, the first head portion 6 is provided with a holder mounting portion 20 to which the syringe holder 15 is detachably mounted.
[0023]
Therefore, the doctor or the like removes the front cover member 26 and the rear cover member 27 from the syringe holder 15 holding the first syringe 11 preliminarily filled with the contrast agent, and attaches the syringe holder 15 to the holder mounting portion 20. As a result, the first syringe 11 is connected to the three-way cock 21. For this reason, since a doctor etc. are hardly exposed to the contrast agent in the 1st syringe 11, exposure by a contrast agent is suppressed. In addition, as needed, it is also possible to inject a contrast medium into a subject by gripping the handle 15a of the syringe holder 15 and manually operating the first syringe 11.
[0024]
The second head unit 7 includes a second syringe 12 filled with physiological saline and a second operation mechanism 14 for automatically operating the second syringe 12. The second operation mechanism 14 includes a drive shaft 16b that drives the piston 12a of the second syringe 12, a motor 17b that rotationally drives the drive shaft 16b, and an encoder 18b that encodes the rotation of the motor 17b. is doing. The drive shaft 16b is provided in parallel with the moving direction of the piston 12a, and a pressing plate 19b that presses the piston 12a is engaged therewith.
[0025]
As shown in FIGS. 1 and 3, the infusion part 8 includes a three-way cock 21 for switching the infusion path, and an infusion tube 22 for injecting a contrast medium and physiological saline into the subject via the three-way cock 21. The connecting tube 23 for connecting the second syringe 12 to the three-way stopcock 21 and the stopcock switching mechanism 24 for switching the state of the three-way stopcock 21 are provided.
[0026]
The three-way cock 21 is connected to the first syringe 11, and one end of the infusion tube 22 is connected to the three-way cock 21. An injection needle 25 is attached to the other end of the infusion tube 22 . In addition, one end of a connection tube 23 is connected to the three-way cock 21, and the other end of the connection tube 23 is connected to the second syringe 12.
[0027]
The three-way stopcock 21 has a first state in which the first syringe 11 communicates with the subject via the infusion tube 22, and a second syringe 12 on the subject side via the infusion tube 22 and the connecting tube 23. There are respectively switched to a second state in which the first syringe 11 and the second syringe 12 are communicated with each other through a connecting tube 23 .
[0028]
The stopcock switching mechanism 24 is electrically connected to the control circuit unit 9, and based on the control signal from the control circuit unit 9, the three-way stopcock 21 is in the first state, the second state, and the third state described above. Switch to and respectively.
[0029]
Although not shown, the control circuit unit 9 includes a drive circuit that rotates and drives the motors 17a and 17b of the first and second head units 6 and 7, a detection circuit that detects signals from the encoders 18a and 18b, and the like. is doing. Further, as shown in FIG. 3, the control circuit unit 9 is electrically connected to a power supply circuit 28 to which external power is supplied. The control circuit unit 9 drives and controls the stopcock switching mechanism 24 in accordance with each A mode and B mode described later.
[0030]
The operation unit 10 includes a plurality of operation buttons 10a for performing various operations and a plurality of display boards 10b for displaying various states. As will be described later, a display indicating the selected A mode or B mode, a set amount of physiological saline filled in the second syringe 12, and the like are displayed on the display board 10b.
[0031]
About the chemical | medical solution injection device 1 comprised as mentioned above, the operation | movement which inject | pours a contrast agent and physiological saline is demonstrated.
[0032]
First, the syringe holder 15 holding the first syringe 11 preliminarily filled with a set amount of contrast agent is mounted in the holder mounting portion 20. Subsequently, the three-way stopcock 21 is switched to the second state, a trace amount of physiological saline is ejected by the second syringe 12, and the air in the infusion tube 22 and the connecting tube 23 is vented. Thereafter, the second head unit 7 is in a standby state by the pressing plate 19b being brought into contact with the piston 12a of the second syringe 12 by the second operation mechanism 14.
[0033]
And the chemical injection device 1 is selectively used between the A mode and the B mode. The case of performing the injection operation in the A mode will be described with reference to the drawings.
[0034]
As shown in FIG. 6 and FIG. 7A, starting from step 31, the stopcock switching mechanism 24 switches the three-way stopcock 21 to the first state based on the control signal from the control circuit unit 9, and the first The contrast medium is injected from the syringe 11 into the subject (step 32).
[0035]
Subsequently, as shown in FIGS. 6 and 7B, the stopcock switching mechanism 24 switches the three-way stopcock 21 to the second state based on the control signal from the control circuit unit 9, and the second syringe 12. Then, a set amount of physiological saline is injected into the subject (step 33), and in step 34, the injection operation in the A mode is completed.
[0036]
In addition, the control circuit unit 9 determines the amount of the physiological saline filled in the second syringe 12 according to the position of the pressing plate 19b in contact with the piston 12b of the second syringe 12 during the above-described standby. To detect. The control circuit unit 9 performs drive control so that the injection operation is disabled when the second syringe 12 is not filled with a physiological saline of a set amount or more.
[0037]
Next, the case of performing the injection operation in the B mode will be described with reference to the drawings.
[0038]
As shown in FIGS. 8 and 9A, starting from step 41, based on the control signal from the control circuit unit 9, the stopcock switching mechanism 24 switches the three-way stopcock 21 to the first state, A contrast medium is injected from the syringe 11 into the subject through the infusion tube 22 (step 42).
[0039]
As shown in FIG. 9B, based on a control signal from the control circuit unit 9, the stopcock switching mechanism 24 switches the three-way stopcock 21 to the third state, and the piston 11a of the first syringe 11 is set to a predetermined amount. For example, about 5 mL is retracted (step 43). Subsequently, as shown in FIG. 9C, a predetermined amount, for example, about 5 mL of physiological saline is transferred from the second syringe 12 into the first syringe 11 with the three-way cock 21 in the third state ( Step 44). As a result, the contrast agent remaining in the first syringe 11 is well mixed into the physiological saline.
[0040]
As shown in FIG. 9 (d), the stopcock switching mechanism 24 switches the three-way stopcock 21 to the first state on the basis of the control signal from the control circuit unit 9, and the physiological saline transferred to the first syringe 11. Water is injected into the subject along with the contrast agent remaining in the first syringe (step 45).
[0041]
Finally, as shown in FIG. 9 (e), the stopcock switching mechanism 24 switches the three-way stopcock 21 to the second state based on the control signal from the control circuit unit 9, and the second syringe 12 sends the test subject to the subject. A set amount of physiological saline is injected (step 46), and in step 47, the injection operation in the B mode ends. Therefore, according to this B mode, the contrast agent remaining in the first syringe 11 and the contrast agent remaining in the infusion tube 22 can be injected into the subject.
[0042]
In addition, the control circuit unit 9 determines the amount of physiological saline filled in the second syringe 12 according to the position of the pressing plate 19b that is in contact with the piston 12b of the second syringe 12 during the above-described standby. To detect. When the second syringe 12 is not filled with, for example, (set amount + 5 mL) or more of physiological saline, the control circuit unit 9 performs drive control so that the injection operation is disabled.
[0043]
As described above, the chemical injection device 1 includes the first state in which the first syringe 11 communicates with the subject, the second state in which the second syringe 12 communicates with the subject, the first syringe 11 and the first syringe 11. The stopcock switching mechanism 24 for switching the three-way stopcock 21 to the third state where the two syringes 12 are communicated, and the stopcock switching mechanism 24 in the first state, the third state, the first state, and the second state. By including the control circuit unit 9 that performs drive control in the B mode that switches in order, the entire amount of the contrast agent filled in the first syringe 11 can be reliably injected into the subject.
[0044]
Moreover, according to this chemical | medical solution injection device 1, since a series of operation | movement which inject | pours a contrast agent and a physiological saline is reliably performed by the automatic control by the control circuit part 9, it depends on the contrast agent etc. which remain | survived in the infusion tube 22 Doctors are prevented from receiving radiation exposure.
[0045]
In addition, although the infusion part 8 mentioned above was comprised so that each infusion path could be switched by the three-way cock 21, you may be comprised so that each infusion path may be opened and closed independently, for example.
[0046]
As shown in FIG. 10, the other infusion part 50 includes injection tubes 51 and 52 connected to the first syringe 11 and the second syringe 12, respectively, and injects contrast medium and physiological saline into the subject. An infusion tube 53, a connecting member 54 that connects the tubes 51, 52, and 53, and an infusion path opening / closing mechanism 56 that opens and closes the infusion channels of the tubes 51, 52, and 53 independently.
[0047]
As each tube 51, 52, 53, for example, a pressure-resistant tube provided with a metal mesh is used.
[0048]
Each infusion path opening / closing mechanism 56 is disposed at a position corresponding to each tube 51, 52, 53, and as shown in FIGS. 11 and 12, a set of sandwiching each tube 51, 52, 53. The holding members 61 and 62, a moving mechanism 63 for moving the other holding member 62 relative to the one holding member 61, and a support member 64 for supporting the holding members 61 and 62 and the moving mechanism 63. ing.
[0049]
The clamping member 61 is fixed to the support piece 64 a of the support member 64. The clamping member 62 is guided so as to be movable in a guide hole provided in the support piece 64 b of the support member 64. Each tube 51, 52, 53 is inserted between the clamping members 61, 62.
[0050]
The moving mechanism 63 includes a cam 66 that moves the clamping member 62, a rotary shaft 67 that rotatably supports the cam 66, a gear 68 that rotationally drives the cam 66, and a motor 69 that rotationally drives the gear 68. Have.
[0051]
The cam 66 is provided at a position facing the lower end of the clamping member 62. The rotary shaft 67 is rotatably supported by the support member 64, and a cam 66 is fixed to one end side. The gear 68 is fixed to the other end side of the rotating shaft 67. The motor 69 is fixed to the support member 64 and has a pinion gear (not shown) that rotationally drives the gear 68. The motor 69 is electrically connected to the control circuit unit 9 and is driven to rotate based on a control signal from the control circuit unit 9.
[0052]
In the infusion channel opening / closing mechanism 56 configured as described above, the cam 66 is rotationally driven via the gear 68 when the motor 69 is rotationally driven by the control circuit unit 9. When the cam 66 is rotationally driven, the clamping member 62 is moved upward, and the tubes 51, 52, 53 are sandwiched between the clamping members 61, 62 and are crushed, so that the infusion path is closed. Similarly, in the infusion path opening / closing mechanism 56, when the cam 66 is rotated, the clamping member 62 is moved downward by its own weight to open the infusion path.
[0053]
In addition, the above-described infusion path opening / closing mechanism 56 is configured to open and close the infusion path by crushing the tubes 51, 52, and 53. Good.
[0054]
Finally, a fluoroscopic image device to which the above-described chemical liquid injector 1 is applied will be briefly described. As shown in FIG. 13, the fluoroscopic image device 2 which is a PET device includes the above-described chemical liquid injector 1, an imaging unit 3 for imaging a subject into which a contrast agent has been injected, and a control for controlling the imaging unit 3. And a unit 4. The chemical solution injector 1 is disposed in the vicinity of the examination table of the imaging unit 3 and injects a contrast medium and physiological saline to a subject lying on the examination table.
[0055]
The chemical injection device according to the present invention is applied to a PET device, but may be used for other fluoroscopic image devices such as a CT (Computed Tomography) scanner and an MRI (Magnetic Resonance Imaging) device. is there.
[0056]
【The invention's effect】
According to the liquid injector according to the present invention as described above, the first to the operation switching means for injecting a liquid medicine in the first chemical liquid in the syringe in a first state in a subject, switching means in the third state a second operation for transferring the second chemical liquid from the second liquid syringe into a first liquid syringe, the third operation switch means for injecting a liquid medicine in the first chemical solution in the syringe to a subject in a first state And the switching means is filled in the first drug solution syringe by performing the drug solution injection operation in a mode having a fourth operation for injecting the drug solution in the second drug solution syringe to the subject in the second state. The entire amount of the first drug solution can be reliably injected into the subject without leaving the contrast medium remaining in the first drug solution syringe or tube.
[Brief description of the drawings]
FIG. 1 is a perspective view showing a chemical liquid injector according to the present invention.
FIG. 2 is a perspective view showing a state where a syringe holder is removed from the chemical liquid injector.
FIG. 3 is a schematic view showing the chemical liquid injector.
FIG. 4 is a perspective view showing a state where a front cover member and a rear cover member are attached to the syringe holder.
FIG. 5 is a perspective view showing a state where a front cover member and a rear cover member are removed from the syringe holder.
FIG. 6 is a flowchart showing an A mode.
FIG. 7 is a schematic diagram showing the operation of the first and second syringes in the A mode.
FIG. 8 is a flowchart showing a B mode.
FIG. 9 is a schematic diagram showing the operation of the first and second syringes in the B mode.
FIG. 10 is a schematic view showing another infusion part.
FIG. 11 is a perspective view showing an infusion opening / closing mechanism.
FIG. 12 is a schematic view showing an infusion opening / closing mechanism.
FIG. 13 is a perspective view showing an imaging apparatus according to the present invention.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Chemical injection device 6 1st head part 7 2nd head part 8 Infusion part 9 Control circuit part 10 Operation part 11 1st syringe 12 2nd syringe 13 1st operation mechanism 14 2nd operation mechanism 15 Syringe Holder 20 Holder mounting portion 21 Three-way stopcock 22 Infusion tube 23 Connection tube 24 Stopcock switching mechanism 28 Power supply circuit portion

Claims (10)

A first chemical syringe filled with the first chemical,
A second chemical syringe filled with the second chemical,
A tube for injecting the first and second chemicals into the subject;
A first state in which the first chemical syringe is communicated with the subject via the tube, a second state in which the second chemical syringe is communicated with the subject, the first chemical syringe and the second Switching means for switching to a third state in which the chemical syringe is communicated,
A first operation of switching the switching means to the first state and injecting a chemical in the first chemical syringe into the subject, and switching the switching means to the third state from the second chemical syringe. A second operation for transferring the second chemical liquid to the first chemical liquid syringe; a third operation for switching the switching means to the first state and injecting the chemical liquid in the first chemical liquid syringe into the subject ; A liquid medicine comprising: a control means for controlling the liquid medicine injection operation in a mode having a fourth action in this order for switching the switching means to the second state and injecting the liquid medicine in the second liquid medicine syringe into the subject. Injection device. The control means selectively selects the mode and another mode in which the switching means is switched in the order of the first state and the second state and the fourth operation is performed after the first operation. The chemical | medical solution injection device of Claim 1 to control. The chemical solution injection device according to claim 1 or 2 , further comprising operation means for automatically operating each of the first chemical solution syringe and the second chemical solution syringe. The chemical switching device according to any one of claims 1 to 3 , wherein the switching means includes a three-way cock. It said switching means, liquid injector according to any one of claims 1 to 3 having an infusion passage opening and closing mechanism for opening and closing the infusion line by pressing the tube. The chemical solution injection device according to any one of claims 1 to 5 , further comprising a holder member that holds the first chemical solution syringe and a holder mounting portion on which the holder member is detachably mounted. The chemical | medical solution injection apparatus of Claim 6 to which the cover member which covers the said 1st chemical | medical solution syringe is attached to the said holder member. The chemical solution injection device according to any one of claims 1 to 7 , wherein the first chemical solution is a contrast medium, and the second chemical solution is a physiological saline. The chemical solution injection device according to claim 8 , wherein the first chemical solution contains a positron nuclide. It includes a liquid injector according to any one of claims 1 to 9, an imaging device for capturing a perspective image of the subject.

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