JP4242544B2 - Syringe pump - Google Patents

Syringe pump Download PDF

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Publication number
JP4242544B2
JP4242544B2 JP2000200687A JP2000200687A JP4242544B2 JP 4242544 B2 JP4242544 B2 JP 4242544B2 JP 2000200687 A JP2000200687 A JP 2000200687A JP 2000200687 A JP2000200687 A JP 2000200687A JP 4242544 B2 JP4242544 B2 JP 4242544B2
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Prior art keywords
plunger head
plunger
syringe pump
force
holding device
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JP2000200687A
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JP2001029462A (en
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ジョン フォード アンドリュー
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Smiths Group PLC
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Smiths Group PLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Syringe pump has plunger head retainer (10) with two retainer arms (111 and 112) mounted on shafts (113 and 114) extending parallel to the syringe axis. Each shaft carries gear (121 and 122), which is engaged by common gear wheel (142) mounted on threaded shaft (146). After the syringe (3) has been loaded in the pump, the plunger head retainer (10) is driven forwards until a pad (107) coupled with a force sensor (108) detects contact with the head (36). This causes the retainer arms to be swung in across the forward side of the plunger head (36) and to be pulled rearwardly against the plunger head. The pump then reduces the force applied by the retainer arms to ensure that the force sensor (108) can respond to force on the plunger (35) during expulsion of liquid from the syringe. <IMAGE>

Description

【０００１】
【発明の属する技術分野】
本発明はバレルに沿って移動できるプランジャを有する注射器を収容する注射器ポンプであって、このプランジャのプランジャヘッドの後面に掛合して、このプランジャに前方に指向する力を加えるようにした前方に向く面を有するプランジャヘッド保持装置を具える注射器ポンプに関するものであり、またその注射器ポンプの操作方法に関するものである。
【０００２】
【従来の技術】
注射器ポンプは予め医薬を充填した注射器から、注入管を通じて、患者に医薬を供給するために使用される。注射器ポンプは注射器のプランジャに力を加え、制御された流速で、医薬を注入管内に駆動する。注射器のバレルからのサイフォン作用の結果として、プランジャが自分自身で動いてしまうのを防止し、プランジャが押し込まれるように、プランジャヘッドを保持する。プランジャヘッドは楔状アームによって、通常、保持されており、これ等アームはプランジャヘッドの前面を横切って移動し、プランジャヘッドの後面をプランジャヘッド保持装置の前方に向く表面に強制的に押し付けて、プランジャヘッドをこの表面に堅くクランプする。種々の注射器によって、プランジャヘッドの寸法、及び太さが変化するから、プランジャヘッド保持装置は全ての異なるプランジャヘッドを受け入れることはできず、そのため、注射器ポンプを使用し得る注射器の範囲は制約を受ける。プランジャヘッド保持装置が確実にプランジャヘッドを保持していないと、プランジャは動いてしまい、注射器から流体をサイフォン作用で排出してしまう。
【０００３】
ポンプ駆動装置によって、プランジャヘッドに作用する力を測定するのが普通であり、これは閉塞によって生ずるような超過圧力を検出するためである。誤った警報を発することなく、超過圧力が低レベルのうちに対応し得ることができれば有利である。しかし、力センサはプランジャヘッドから比較的遠方に設置されているのが普通であり、従って、駆動系に作用する摩擦力や、その他の力をも含めた測定値にならざるを得ない。
【０００４】
【発明が解決しようとする課題】
本発明の目的は先行技術の注射器ポンプの欠点を除去し、広範囲に寸法、形状の異なる注射器に的確に使用することができ、異常な圧力上昇に安全に対処できる注射器ポンプ、及びその操作方法を得るにある。
【０００５】
【課題を解決するための手段】
この目的を達成するため、本発明注射器ポンプは、頭書に記載した注射器ポンプにおいて、プランジャの移動中、このプランジャヘッド保持装置によってプランジャヘッドに作用する力に応動する力センサをプランジャヘッド保持装置に設けたことを特徴とする。
【０００６】
また本発明注射器ポンプの操作方法はプランジャヘッド保持装置が後方位置になるようポンプに注射器を設置し、このプランジャヘッド保持装置がプランジャヘッドの後面に接触するまで、このプランジャヘッド保持装置を前方に移動させ、プランジャヘッドがプランジャヘッド保持装置に対し相対的に前方に移動するのを防止するよう、プランジャヘッド保持装置によってプランジャヘッドを保持するが、このプランジャヘッドと、プランジャヘッド保持装置との間に加わる力を継続して監視し、プランジャヘッド保持装置と、プランジャヘッドとの間の上記力を監視しながら、プランジャヘッド保持装置を前進させて、プランジャを前方に動かし、注射器の内容物を分配する工程から成ることを特徴とする。
【０００７】
【発明の実施の形態】
上記力センサを介して、保持装置に連結されたパッドをこの保持装置に設け、このパッドを介して、プランジャに前方に指向する力を加えるよう構成するのが好適である。このパッドを前方に押圧するように配置されたばねを保持装置に設けることができる。最初、保持装置に対し後方にプランジャヘッドを引っ張って、センサに加わる力を増大すると共に、次にこのセンサに加わる力を釈放するよう保持装置を配置するのが好適である。
【０００８】
また、他の態様における本発明注射器ポンプはプランジャヘッドの前面を横切って横方向に移動することができると共に、プランジャヘッドの上記前面に向け軸線方向に後方に移動することができ、横方向、及び軸線方向の両方向に移動できる少なくとも１個の保持部材をプランジャヘッド保持装置に設けたことを特徴とする。
【０００９】
プランジャヘッドの後面と、前方に向く面との間に力を加えるよう、最初に保持部材の一方、又はおのおのを保持装置に対し軸線方向に、後方に移動させると共に、次に上記力を減少させるよう、保持部材の一方、又はおのおのを軸線方向前方に移動させるように保持装置を作動させ得るよう構成するのが好適である。上記軸から延びるアームを保持部材の一方、又はおのおのに設け、注射器の軸線に平行にこの軸を延在させ、上記アームをこの軸の周りに回転させることによって、このアームを横方向に移動し得るよう構成することができ、この軸の一方、又はおのおのをその軸線に沿って動かすことによって、アームの一方、又はおのおのを軸線方向に移動させるよう構成することもできる。また、回転可能なねじ軸と、このねじ軸上に螺着された歯車とを有する歯車組立体によって、この軸の一方、又はおのおのを駆動し、上記ねじ軸を回転することによって、最初、上記歯車をこのねじ軸に沿って、このねじ軸の端部まで動かし、その後、このねじ軸の回転を継続することによって、この歯車を回転させるよう構成するのが好適である。
【００１０】
【実施例】
まず、図１において、このポンプは外側ハウジング１を有し、このハウジング１はその前面に、通常の種類の注射器３を収容する形状の凹所２を有する。この注射器３は円筒バレル３０を有し、その前端に送出口、即ちノーズ３１を有し、後端にフランジ、即ち耳片３２を有する。ノーズ３１を注入管５に連結し、注射器のプランジャ３５を押圧することによって、注入管５を通じて、注射器内の医薬液体を患者の身体内に分配することができる。このポンプは親ねじ８を有する通常の駆動機構７を具え、この親ねじ８をモータ９によって駆動すると共に、プランジャ３５のヘッド３６に、この親ねじ８を掛合させるための新規な保持機構、即ち保持装置１０に親ねじ８を連結する。モータ９は制御ユニット１１によって駆動し、制御ユニット１１はキーパッド１２、又はその他のユーザ入力手段、及び種々のセンサから入力信号を受ける。また、制御ユニット１１はディスプレイ１３に出力を供給する。
【００１１】
図２、及び図３において、プランジャヘッド保持機構、即ち保持装置１０は前部１００、後部１０１から成る外側ケーシングを有する。前部１００はその外面１０３に、その端縁に向く円形孔１０２を有し、注射器３に平行に延びる管状スリーブ１０４（図１参照）をこの円形孔１０２に収容する。スリーブ１０４を親ねじ８の周りに、軸線方向に取り付け、親ねじの回転によって、スリーブ、及び保持機構１０を軸線方向に前後に移動させる。
【００１２】
また、ケーシングの前面１０３には一層大きな浅い円形凹所１０５を設け、この円形凹所１０５に中心孔１０６を設ける。円形パッド１０７を凹所１０５内に設置する。ケーシングの内側にあって、孔１０６から突出するストレインビーム、又はストレインゲージ１０８の形状の後方に延びる力センサをこのパット１０７に設ける。簡明のため、図２、及び図３では機構１０の内部構成部分上にパッド１０７を取り付けて示しているが、実際上、パッド１０７は外側ケーシングの前部１００の外面上に設置されている。パッド１０７はストレインビーム１０８の周りのコイルばね１０９によって軸線方向外方に弾性的に押圧されている。ストレインビーム１０８、又はストレインゲージはパッド１０７上の軸線方向の圧力を表す出力信号を制御ユニット１１に送る。
【００１３】
２個のアーム１１１、１１２を前面１０３に平行に延在し、前方に、この前面１０３に対し僅かな距離離間する。これ等のアーム１１１、１１２は休止位置において、パッド１０７とほぼ同軸であるアーク状曲線に沿い、これ等アームの全長に沿って湾曲している。アーム１１１、１１２はそれぞれの軸１１３、１１４に取り付けられており、これ等軸１１３、１１４は注射器３の軸線に平行に延在しており、ケーシングの前面１０３のブッシュ１１５、１１６を貫通して、端縁に向け突出している。軸１１３、１１４の後端は保持機構１０内に側方に延在するベース板１２０に支承されている。軸１１３、１１４はその長さ方向に沿って軸線方向に移動することができると共に、その軸線の周りに回転することができる。各軸１１３、１１４は扇形歯車１２１、１２２を支持するが、この扇形歯車に形成した蝶形溝孔１２３、１２４を有する孔によって、この扇形歯車１２１、１２２は軸１１３、１１４に取り付けられている。
【００１４】
溝孔１２３、１２４内にそれぞれ設置された２個の半径方向に突出するピン１２５、１２６を各軸１１３、１１４によって支持し、これ等溝孔の両側にこれ等ピンが掛合することによって限定される小さな角度にわたり、扇形歯車１２１、１２２は軸１１３、１１４に対し回転することができる。扇形歯車の一側に、各軸にクリップ１２７を取り付け、扇形歯車が軸に沿って軸線方向に移動するのを防止する。扇形歯車の反対方向への移動はピン１２５、１２６によって防止されている。ばね（図示せず）を各軸１１３、１１４上のクリップ１２７に取り付け、一方の軸１１３をケーシングの前面１０３に対し相対的に時計方向に回転させる弾性押圧力を軸１１３に加え、他方の軸１１４を反時計方向に回転させる弾性押圧力を軸１１４に加える。従って、これ等ばねはアーム１１１、１１２を相互に接近するよう内方に揺動させるように押圧する。
【００１５】
各扇形歯車１２１、１２２は歯車の歯の端縁の周りに溝１３０を有し、各扇形歯車を２個の平行な離間した扇形歯車に分割する。一方の扇形歯車１２１を直接、中心歯車副組立体１４０に噛合させると共に、この中心歯車副組立体に駆動される遊転歯車１４１に他方の扇形歯車１２２を噛合させる。中心歯車副組立体１４０を図４に最も明瞭に示す。この中心歯車副組立体は円形の歯車１４２を有し、その軸線方向の長さに沿う中央部に半径方向に突出するフランジ１４３を設ける。このフランジ１４３は扇形歯車１２１の溝１３０内に嵌着できる形状である。歯車１４２をボス１４４に固着するが、このボス１４４の内面には角ねじの輪郭の螺旋ねじ、即ちねじ１４５を有する。また、中心歯車副組立体１４０は中空軸１４６を有し、この中空軸１４６はその外面に螺旋ねじ、即ちねじを有する。このねじはボス１４４の内面のねじ１４５に整合し、螺合する。
【００１６】
軸１４６の後端に平歯車１４７を設ける。平歯車１４７と軸１４６とは前端にフランジ１４９を有する内部スピンドル１４８上で、自由に回転することができる。中心歯車副組立体１４０をベース板１２０に取り付け、軸１４６を注射器の軸線に平行に延在させる。プランジャヘッド保持機構１０内の電動機１５０に連結された歯車列に平歯車１４７を噛合させる。歯車１４２の回転を防止した状態で、平歯車１４７を回転させると、歯車１４２はねじ軸、即ち中空軸１４６に沿って移動する。この移動は中空軸１４６の長さによって制限を受ける。アーム１１１、１１２、又は軸１１３、１１４の角度位置に応動するセンサ（図示せず）をもこの保持機構１０は具える。アームがその極限外側位置に動き終わった時、それを検知するようにこのセンサを設置する。
【００１７】
最初、モータ１５０を正規方向に回転させ、平歯車１４７、及びねじ軸、即ち中空軸１４６を時計方向に回転させ、これにより、中空軸１４６に沿って、歯車１４２を前方に動かす。また、この歯車１４２の前進運動により、（歯車１４２のフランジ１４３が扇形歯車の溝１３０に入っているため）扇形歯車１２３、１２４をも前方に動かし、従って、アーム１１１、１１２を前方に動かす。中空軸１４６に沿って移動する歯車１４２が、フランジ１４９との掛合によって制限される最大移動限界位置に達した時、中空軸１４６の回転を継続すれば、歯車１４２は、もはや、中空軸に沿って移動できず、中空軸と共に回転せざるを得ないため、歯車１４２は時計方向に回転する。これにより、遊転歯車１４１を反時計方向に回転させる。従って、中心歯車副組立体１４０に直接、噛合する扇形歯車１２１を反時計方向に回転させ、中心歯車副組立体１４０に遊転歯車１４１を介して噛合する扇形歯車１２２を時計方向に回転させる。これにより、アーム１１１、１１２を互いに開くように、即ち離れるように揺動させる。アーム１１１、１１２が最大に開いたことを上記のアーム位置センサが検出するまで、アーム１１１、１１２は開くように揺動し、アーム１１１、１１２が最大に開いたのを検出した時、制御ユニット１１はモータ１５０が正規方向に回転するのを停止させる。
【００１８】
この時、保持機構１０は注射器のプランジャヘッド３６を収容する用意ができた状態にある。注射器３をこのポンプ内に装着し、モータ９を付勢して、親ねじ８を比較的早く回転し、パッド１０７がプランジャヘッド３６の後面に接触するまで、プランジャヘッド保持機構１０を前方に駆動する。パッド１０７の最初の接触は光検出器（図示せず）によって検知され、検知すると、この検出器はストレインビーム、即ちストレインゲージ１０８が僅かなひずみを計量するまで、保持機構１０の前方への運動を遅くする。僅かなひずみが検出されると、親ねじ８が更に回転するのを制御ユニット１１によって停止させ、プランジャヘッド保持機構１０内のモータ１５０を反対方向に付勢する。これにより、ねじ軸、即ち中空軸１４６を反時計方向に回転し、歯車１４２も反時計方向に回転し、これにより遊転歯車１４１を時計方向に回転する。
【００１９】
歯車１４２の反時計方向の回転と、遊転歯車１４１の時計方向の回転とによって、扇形歯車１２１と１２２とをそれぞれ時計方向と、反時計方向とに回転させる。上記のばねの力によってアーム１１１、１１２を閉位置に集合するように揺動させる。アーム１１１、１１２はプランジャ３５の軸に接触するまで集合するように揺動し、プランジャ３５の軸に接触すれば、アームが更に回転するのを防止する。歯車の一部がケーシングの前部１００の止めに接触するまで、扇形歯車１２１、１２２の溝孔１２３、１２４は、これ等扇形歯車１２１、１２２の更に数度だけの回転を許容するが、歯車の一部がケーシングの前部１００の止めに接触することによって、中心歯車組立体が更に回転するのを防止する。扇形歯車の溝孔１２３、１２４が存在することによって、（プランジャ軸との掛合によって限定された）一部閉じた位置に、アーム１１１、１１２を停止させることができると共に、モータの回転方向を反転した時、アーム１１１、１１２を完全開放位置に確実に戻して揺動させることができる。
【００２０】
モータ１５０によって、ねじ軸、即ち中空軸１４６を継続して回転することによって、中空軸１４６に沿って、歯車１４２を引張り、アーム１１１、１１２も引張る。これは扇形歯車１２１、１２２の溝１３０内に、フランジ１４３が掛合しているからである。従って、アーム１１１、１１２がプランジャヘッド３６の前面に掛合するまで、アーム１１１、１１２は後方に引張られる。アームがプランジャヘッドに掛合した時、保持機構１０に対し相対的に、パッド１０７の前面に向け、プランジャヘッド３６を後方に引張り、ストレインビーム、又はストレインゲージ１０８に加わる圧力を増大させる。圧力のこの増大を検知した時、ポンプ制御ユニット１１はモータ１５０を停止させ、そしてこのモータを数ステップ逆回転し、パッド１０７の後面と、凹所１０５の床との間に所定の間隙を生ぜしめる。次に親ねじ８を正規方向に回転して、保持機構１０を動かし、従って、プランジャ３５を前方に動かし、注射器３の内容物を必要な速度で分配する。
【００２１】
パッド１０７と、ストレインビーム１０８とを介して、プランジャヘッド３６を保持機構１０に連結すると共に、パッドの後面と、凹所１０５の床との間に間隙があるから、ストレインビームは保持機構によってプランジャ３５に作用する圧力に応動すると共に、実際に、プランジャを移動させて、注射器３から医薬を押し出す。注入管５内に障害物があって、閉塞していたり、注入管５が詰まっている場合には、ストレインゲージ１０８に加われる圧力は直ちに増大する。本発明の構成によって、プランジャに加わる圧力を直接、測定することができるから、本発明装置は圧力の僅かな増大に対しても敏感である。
【００２２】
このプランジャヘッド保持機構は広範囲のプランジャヘッドに対して使用することができる。これは保持アームを離間し、次にこれ等保持アームを戻して引張って、プランジャヘッドをクランプする作用により、ヘッドの寸法、形状の広範囲な変化に応じることができるからである。
【図面の簡単な説明】
【図１】 本発明ポンプの簡単化した全体の線図である。
【図２】 本発明ポンプのプランジャヘッド保持機構の下から見た分解斜視図である。
【図３】 本発明ポンプのプランジャヘッド保持機構の後側から見た分解斜視図である。
【図４】 本発明ポンプのプランジャヘッド保持機構内の副組立体の拡大斜視図である。
【符号の説明】
１ 外側ハウジング
３ 注射器
１０ プランジャヘッド保持装置、保持機構、プランジャ保持機構
３０ 円筒バレル
３５ プランジャ
３６ ヘッド
１０７ 円形パッド
１０８ ストレインビーム、ストレインゲージ、力センサ
１０９ コイルばね
１１１、１１２ アーム
１１３、１１４ 軸
１２１、１２２ 扇形歯車
１４０ 中心歯車副組立体
１４２ 歯車、共通歯車
１４６ 中空軸、ねじ軸[0001]
BACKGROUND OF THE INVENTION
The present invention is a syringe pump containing a syringe having a plunger that is movable along a barrel, and is directed to the rear surface of the plunger head of the plunger so as to apply a force directed forward to the plunger. The present invention relates to a syringe pump having a plunger head holding device having a surface, and to a method of operating the syringe pump.
[0002]
[Prior art]
Syringe pumps are used to deliver medication to a patient through an infusion tube from a pre-filled syringe. The syringe pump applies force to the syringe plunger and drives the medicament into the infusion tube at a controlled flow rate. As a result of siphoning from the barrel of the syringe, the plunger is prevented from moving by itself and the plunger head is held so that the plunger is pushed in. Plunger heads are usually held by wedge-shaped arms, which move across the front surface of the plunger head and force the rear surface of the plunger head against the front-facing surface of the plunger head holding device, Clamp the head firmly to this surface. Because the size and thickness of the plunger head varies with different syringes, the plunger head holding device cannot accept all different plunger heads, so the range of syringes that can use the syringe pump is limited. . If the plunger head holding device does not securely hold the plunger head, the plunger moves and discharges fluid from the syringe by siphon action.
[0003]
It is common to measure the force acting on the plunger head by means of a pump drive, in order to detect an overpressure as caused by a blockage. It would be advantageous if the overpressure could be accommodated at a low level without issuing a false alarm. However, the force sensor is usually installed relatively far from the plunger head. Therefore, the force sensor must be a measured value including a frictional force acting on the drive system and other forces.
[0004]
[Problems to be solved by the invention]
An object of the present invention is to eliminate the drawbacks of prior art syringe pumps, and to provide a syringe pump that can be accurately used in a wide range of sizes and shapes of syringes and can safely handle abnormal pressure rises, and a method of operating the same. To get.
[0005]
[Means for Solving the Problems]
In order to achieve this object, the syringe pump according to the present invention is provided with a force sensor that responds to a force acting on the plunger head by the plunger head holding device during movement of the plunger in the syringe pump described in the introduction. It is characterized by that.
[0006]
The operation method of the syringe pump of the present invention is such that the syringe is installed in the pump so that the plunger head holding device is in the rear position, and the plunger head holding device is moved forward until the plunger head holding device contacts the rear surface of the plunger head The plunger head is held by the plunger head holding device so as to prevent the plunger head from moving forward relative to the plunger head holding device, and is added between the plunger head and the plunger head holding device. Advancing the plunger head holding device to move the plunger forward and dispensing the contents of the syringe while continuously monitoring the force and monitoring the force between the plunger head holding device and the plunger head It is characterized by comprising.
[0007]
DETAILED DESCRIPTION OF THE INVENTION
It is preferable that the holding device is provided with a pad connected to the holding device via the force sensor, and a force directed forward is applied to the plunger through the pad. A spring arranged to press the pad forward can be provided on the holding device. It is preferred to initially place the holding device to pull the plunger head rearward relative to the holding device to increase the force applied to the sensor and then release the force applied to the sensor.
[0008]
In another aspect, the syringe pump of the present invention can move laterally across the front surface of the plunger head and can move rearward in the axial direction toward the front surface of the plunger head. The plunger head holding device is provided with at least one holding member that can move in both axial directions.
[0009]
First, one or each of the holding members is moved axially rearward with respect to the holding device, and then the force is reduced, so as to apply a force between the rear face of the plunger head and the face facing forward. Thus, it is preferable that one of the holding members or each of the holding members can be operated so as to move forward in the axial direction. An arm extending from the axis is provided on one or each of the holding members, the axis extends parallel to the axis of the syringe, and the arm is moved laterally by rotating the arm about the axis. It can also be configured to move one or each of the arms axially by moving one or each of the axes along its axis. In addition, by driving one or each of the shafts by a gear assembly having a rotatable screw shaft and a gear screwed onto the screw shaft, and rotating the screw shaft, It is preferred that the gear be rotated by moving the gear along the screw shaft to the end of the screw shaft and then continuing to rotate the screw shaft.
[0010]
【Example】
First, in FIG. 1, the pump has an outer housing 1, which has a recess 2 on its front face that is shaped to accommodate a conventional type of syringe 3. The syringe 3 has a cylindrical barrel 30 having a delivery port or nose 31 at its front end and a flange or ear piece 32 at its rear end. By connecting the nose 31 to the infusion tube 5 and pressing the plunger 35 of the syringe, the medicinal liquid in the syringe can be distributed into the patient's body through the infusion tube 5. This pump comprises a normal drive mechanism 7 having a lead screw 8, which is driven by a motor 9 and a new holding mechanism for engaging the lead screw 8 with the head 36 of the plunger 35, i.e. The lead screw 8 is connected to the holding device 10. The motor 9 is driven by a control unit 11, which receives input signals from a keypad 12, or other user input means, and various sensors. The control unit 11 also supplies an output to the display 13.
[0011]
2 and 3, the plunger head holding mechanism, that is, the holding device 10 has an outer casing having a front part 100 and a rear part 101. The front part 100 has a circular hole 102 on its outer surface 103 facing its edge, and a tubular sleeve 104 (see FIG. 1) extending parallel to the syringe 3 is accommodated in this circular hole 102. The sleeve 104 is attached around the lead screw 8 in the axial direction, and the sleeve and the holding mechanism 10 are moved back and forth in the axial direction by rotation of the lead screw.
[0012]
Further, a larger shallow circular recess 105 is provided on the front surface 103 of the casing, and a central hole 106 is provided in the circular recess 105. A circular pad 107 is placed in the recess 105. The pad 107 is provided with a force sensor which is located inside the casing and extends rearward in the shape of a strain beam or a strain gauge 108 protruding from the hole 106. For simplicity, FIGS. 2 and 3 show the pad 107 mounted on the internal components of the mechanism 10, but in practice the pad 107 is placed on the outer surface of the front portion 100 of the outer casing. The pad 107 is elastically pressed outward in the axial direction by a coil spring 109 around the strain beam 108. The strain beam 108 or strain gauge sends an output signal representing the axial pressure on the pad 107 to the control unit 11.
[0013]
The two arms 111 and 112 extend in parallel to the front surface 103 and are spaced forward from the front surface 103 by a small distance. These arms 111, 112 are curved along the full length of these arms in a rest position along an arcuate curve that is substantially coaxial with the pad 107. The arms 111, 112 are attached to respective shafts 113, 114, which extend parallel to the axis of the syringe 3 and pass through the bushes 115, 116 on the front face 103 of the casing. , Protruding towards the edge. The rear ends of the shafts 113 and 114 are supported by a base plate 120 that extends laterally into the holding mechanism 10. The shafts 113 and 114 can move axially along their length and can rotate about the axis. Each of the shafts 113 and 114 supports the sector gears 121 and 122, and the sector gears 121 and 122 are attached to the shafts 113 and 114 by holes having butterfly-shaped grooves 123 and 124 formed in the sector gears. .
[0014]
Two radially projecting pins 125 and 126 installed in the slots 123 and 124 are supported by the shafts 113 and 114, respectively, and these pins are engaged with both sides of the slots. Over a small angle, the sector gears 121, 122 can rotate relative to the shafts 113, 114. A clip 127 is attached to each shaft on one side of the sector gear to prevent the sector gear from moving in the axial direction along the axis. The movement of the sector gear in the opposite direction is prevented by pins 125, 126. A spring (not shown) is attached to the clip 127 on each of the shafts 113 and 114, and an elastic pressing force is applied to the shaft 113 to rotate one shaft 113 relative to the front surface 103 of the casing in a clockwise direction. An elastic pressing force that rotates the counterclockwise direction 114 is applied to the shaft 114. Accordingly, these springs press the arms 111 and 112 so as to swing inward so as to approach each other.
[0015]
Each sector gear 121, 122 has a groove 130 around the edge of the gear teeth and divides each sector gear into two parallel spaced apart sector gears. One sector gear 121 is directly meshed with the central gear subassembly 140, and the other sector gear 122 is meshed with the idler gear 141 driven by the central gear subassembly. The central gear subassembly 140 is most clearly shown in FIG. The central gear subassembly has a circular gear 142, and a flange 143 projecting in the radial direction is provided at the center along the axial length thereof. The flange 143 has a shape that can be fitted into the groove 130 of the sector gear 121. The gear 142 is fixed to the boss 144, and the inner surface of the boss 144 has a helical screw having a square screw profile, that is, a screw 145. The central gear subassembly 140 also has a hollow shaft 146 that has a helical screw or screw on its outer surface. This screw is aligned with and screwed into the screw 145 on the inner surface of the boss 144.
[0016]
A spur gear 147 is provided at the rear end of the shaft 146. Spur gear 147 and shaft 146 are free to rotate on an internal spindle 148 having a flange 149 at the front end. A central gear subassembly 140 is attached to the base plate 120 and the shaft 146 extends parallel to the syringe axis. A spur gear 147 is engaged with a gear train connected to the electric motor 150 in the plunger head holding mechanism 10. When the spur gear 147 is rotated in a state where the rotation of the gear 142 is prevented, the gear 142 moves along the screw shaft, that is, the hollow shaft 146. This movement is limited by the length of the hollow shaft 146. The holding mechanism 10 also includes a sensor (not shown) that responds to the angular positions of the arms 111 and 112 or the shafts 113 and 114. This sensor is installed to detect when the arm has moved to its extreme outer position.
[0017]
First, the motor 150 is rotated in the normal direction, and the spur gear 147 and the screw shaft, that is, the hollow shaft 146 are rotated clockwise, thereby moving the gear 142 forward along the hollow shaft 146. The forward movement of the gear 142 also moves the sector gears 123 and 124 forward (because the flange 143 of the gear 142 is in the groove 130 of the sector gear), thus moving the arms 111 and 112 forward. When the gear 142 moving along the hollow shaft 146 reaches the maximum travel limit position limited by engagement with the flange 149, if the rotation of the hollow shaft 146 is continued, the gear 142 is no longer along the hollow shaft. Therefore, the gear 142 rotates in the clockwise direction. Thereby, the idle gear 141 is rotated counterclockwise. Accordingly, the sector gear 121 that meshes directly with the central gear subassembly 140 is rotated counterclockwise, and the sector gear 122 that meshes with the central gear subassembly 140 via the idle gear 141 is rotated clockwise. Accordingly, the arms 111 and 112 are swung so as to open, that is, away from each other. Until the arm position sensor detects that the arms 111 and 112 are fully opened, the arms 111 and 112 swing so as to open, and when the arms 111 and 112 are detected to be fully opened, the control unit 11 stops the motor 150 from rotating in the normal direction.
[0018]
At this time, the holding mechanism 10 is ready to receive the plunger head 36 of the syringe. The syringe 3 is mounted in the pump, the motor 9 is energized, the lead screw 8 is rotated relatively quickly, and the plunger head holding mechanism 10 is driven forward until the pad 107 contacts the rear surface of the plunger head 36. To do. The initial contact of the pad 107 is detected by a light detector (not shown) which, when detected, moves the holding mechanism 10 forward until the strain beam or strain gauge 108 measures a slight strain. To slow down. When a slight strain is detected, the control unit 11 stops further rotation of the lead screw 8 and biases the motor 150 in the plunger head holding mechanism 10 in the opposite direction. Thereby, the screw shaft, that is, the hollow shaft 146 is rotated counterclockwise, and the gear 142 is also rotated counterclockwise, whereby the idle gear 141 is rotated clockwise.
[0019]
By rotating the gear 142 counterclockwise and rotating the idle gear 141 clockwise, the sector gears 121 and 122 are rotated clockwise and counterclockwise, respectively. The arms 111 and 112 are swung so as to gather at the closed position by the force of the spring. The arms 111 and 112 swing so as to gather until they come into contact with the axis of the plunger 35, and if they come into contact with the axis of the plunger 35, the arms are prevented from further rotating. The slots 123, 124 in the sector gears 121, 122 allow the fan gears 121, 122 to rotate only a few degrees until part of the gears come into contact with the stop on the front part 100 of the casing. A portion of which contacts the stop on the front 100 of the casing to prevent further rotation of the central gear assembly. The presence of the fan gear slots 123 and 124 allows the arms 111 and 112 to stop at a partially closed position (limited by engagement with the plunger shaft) and reverses the direction of rotation of the motor. In this case, the arms 111 and 112 can be reliably returned to the fully opened position and swung.
[0020]
By continuously rotating the screw shaft, that is, the hollow shaft 146 by the motor 150, the gear 142 is pulled along the hollow shaft 146, and the arms 111 and 112 are also pulled. This is because the flange 143 is engaged in the groove 130 of the sector gears 121 and 122. Accordingly, the arms 111 and 112 are pulled backward until the arms 111 and 112 are engaged with the front surface of the plunger head 36. When the arm is engaged with the plunger head, the plunger head 36 is pulled rearward relative to the holding mechanism 10 toward the front surface of the pad 107, and the pressure applied to the strain beam or the strain gauge 108 is increased. Upon detecting this increase in pressure, the pump control unit 11 stops the motor 150 and reverses the motor several steps backwards, creating a predetermined gap between the rear surface of the pad 107 and the floor of the recess 105. Close. The lead screw 8 is then rotated in the normal direction to move the holding mechanism 10 and thus move the plunger 35 forward to dispense the contents of the syringe 3 at the required speed.
[0021]
The plunger head 36 is connected to the holding mechanism 10 via the pad 107 and the strain beam 108, and there is a gap between the rear surface of the pad and the floor of the recess 105. In response to the pressure acting on 35, the plunger is actually moved to push the medicine out of the syringe 3. If there is an obstacle in the injection tube 5 that is blocked or the injection tube 5 is clogged, the pressure applied to the strain gauge 108 immediately increases. Since the pressure applied to the plunger can be directly measured by the configuration of the present invention, the device of the present invention is sensitive to a slight increase in pressure.
[0022]
This plunger head holding mechanism can be used for a wide range of plunger heads. This is because the holding arms are separated, and then the holding arms are pulled back and pulled to clamp the plunger head, so that a wide range of head size and shape changes can be accommodated.
[Brief description of the drawings]
FIG. 1 is a simplified overall diagram of a pump of the present invention.
FIG. 2 is an exploded perspective view of the pump of the present invention as viewed from below the plunger head holding mechanism.
FIG. 3 is an exploded perspective view seen from the rear side of the plunger head holding mechanism of the pump of the present invention.
FIG. 4 is an enlarged perspective view of a subassembly in a plunger head holding mechanism of the pump of the present invention.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 Outer housing 3 Syringe 10 Plunger head holding device, holding mechanism, plunger holding mechanism 30 Cylindrical barrel 35 Plunger 36 Head 107 Circular pad 108 Strain beam, Strain gauge, Force sensor 109 Coil spring 111, 112 Arm 113, 114 Shaft 121, 122 Fan gear 140 Central gear subassembly 142 Gear, common gear 146 Hollow shaft, screw shaft

Claims (8)

バレル（３０）に沿って移動できるプランジャ（３５）を有する注射器（３）を収容する注射器ポンプであって、前記プランジャのプランジャヘッド（３６）の後面に掛合して、このプランジャに前方に指向する力を加えるようにした前方に向く面（１０７）を有するプランジャヘッド保持装置（１０）を具える注射器ポンプにおいて、前記プランジャヘッド保持装置（１０）には、前記プランジャ（３５）の移動中、初期的に前記プランジャヘッド（３６）を軸線方向後方に引っ張って移動させ、その後この引っ張り力を減少するよう作動する少なくとも１個の保持部材（１１１、１１２）を設け、また前記プランジャヘッド（３６）に作用する力に応動する力センサ（１０８）を前記プランジャヘッド保持装置（１０）に設け、前記力センサ（１０８）には、前記少なくとも１個の保持部材（１１１、１１２）により生ずる引っ張り力で初期的に力が増大し、次にこの力が釈放されるようにしたことを特徴とする注射器ポンプ。  A syringe pump containing a syringe (3) having a plunger (35) movable along a barrel (30), which engages the rear surface of the plunger head (36) of the plunger and is directed forward to the plunger In a syringe pump comprising a plunger head holding device (10) having a forward facing surface (107) adapted to apply force, the plunger head holding device (10) includes an initial position during movement of the plunger (35). In particular, the plunger head (36) is pulled and moved rearward in the axial direction, and thereafter, at least one holding member (111, 112) that operates to reduce the pulling force is provided, and the plunger head (36) is provided. A force sensor (108) that responds to the acting force is provided in the plunger head holding device (10), and the force sensor is provided. The syringe pump is characterized in that the force is initially increased by the tensile force generated by the at least one holding member (111, 112) and then the force is released. . 前記力センサ（１０８）を介して、前記保持装置に連結されたパッド（１０７）をこの保持装置（１０）に設け、前記パッドを介して前記プランジャ（３５）に前記前方に指向する力を加えるよう構成したことを特徴とする請求項１に記載の注射器ポンプ。  A pad (107) connected to the holding device is provided in the holding device (10) through the force sensor (108), and a force directed to the front is applied to the plunger (35) through the pad. The syringe pump according to claim 1, which is configured as described above. 前記パッド（１０７）を前方に押圧するように配置されたばね（１０９）を前記保持装置（１０）に設けたことを特徴とする請求項２に記載の注射器ポンプ。  The syringe pump according to claim 2, characterized in that the holding device (10) is provided with a spring (109) arranged to press the pad (107) forward. 請求項１〜３のうちいずれか一項に記載の注射器ポンプにおいて、前記プランジャヘッド（３６）の前面を横切って横方向に移動することができると共に、前記プランジャヘッドの前記前面に向け軸線方向に後方に移動することができ、横方向、及び軸線方向の両方向に移動できる少なくとも１個の保持部材（１１１、１１２）を前記プランジャヘッド保持装置（１０）に設けた注射器ポンプ。 The syringe pump according to any one of the preceding claims , wherein the syringe pump can move laterally across the front surface of the plunger head (36) and is axially directed toward the front surface of the plunger head. A syringe pump in which the plunger head holding device (10) is provided with at least one holding member (111, 112) that can move rearward and move in both a lateral direction and an axial direction. 前記プランジャヘッド（３６）の前記後面と、前記前方に向く面（１０７）との間に力を加えるよう最初に前記保持部材（１１１、１１２）の一方、又はおのおのを前記保持装置（１０）に対し軸線方向後方に移動させると共に、次に前記力を減少させるよう前記保持部材（１１１、１１２）の一方、又はおのおのを軸線方向前方に移動させるように前記保持装置（１０）を作動させ得るよう構成したことを特徴とする請求項４に記載の注射器ポンプ。  First, one or each of the holding members (111, 112) is applied to the holding device (10) so as to apply a force between the rear surface of the plunger head (36) and the front surface (107). The holding device (10) may be actuated to move axially rearward and then move one or each of the holding members (111, 112) axially forward to reduce the force. The syringe pump according to claim 4, wherein the syringe pump is configured. 軸（１１３、１１４）から延びるアーム（１１１、１１２）を前記保持部材の一方、又はおのおのに設け、前記注射器（３）の軸線に平行に前記軸を延在させ、前記アームをこの軸の周りに回転させることによって前記アームを横方向に移動し得るよう構成したことを特徴とする請求項４、又は５に記載の注射器ポンプ。  Arms (111, 112) extending from the shafts (113, 114) are provided on one or each of the holding members, the shafts extend parallel to the axis of the syringe (3), and the arms are moved around the axes. The syringe pump according to claim 4 or 5, wherein the arm can be moved in a lateral direction by rotating the arm to the right. 前記軸（１１３、１１４）の一方、又はおのおのをその軸線に沿って動かすことによって、前記アーム（１１１、１１２）の一方、又はおのおのを軸線方向に移動させるよう構成したことを特徴とする請求項６に記載の注射器ポンプ。  The one or each of the arms (111, 112) is moved in the axial direction by moving one or each of the shafts (113, 114) along the axis thereof. 6. The syringe pump according to 6. 回転可能なねじ軸（１４６）と、このねじ軸上に螺着された歯車（１４２）とを有する歯車組立体（１４０）によって、前記軸（１１３、１１４）の一方、又はおのおのを駆動し、前記ねじ軸を回転することによって、最初、前記歯車をこのねじ軸に沿って、このねじ軸の端部まで動かし、その後、このねじ軸の回転を継続することによって前記歯車を回転させるよう構成した請求項６、又は７に記載の注射器ポンプ。  One or each of the shafts (113, 114) is driven by a gear assembly (140) having a rotatable screw shaft (146) and a gear (142) screwed onto the screw shaft; By rotating the screw shaft, the gear is first moved along the screw shaft to the end of the screw shaft, and then the gear is rotated by continuing the rotation of the screw shaft. The syringe pump according to claim 6 or 7.
JP2000200687A 1999-07-03 2000-07-03 Syringe pump Expired - Fee Related JP4242544B2 (en)

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CA2312586A1 (en) 2001-01-03
IL136902A (en) 2004-09-27
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