JP4178109B2 - Dialysis container - Google Patents

Description

  The present invention relates to a dialysis container as described in the first stage of claim 1.

  Conventionally, in dialysis systems, it is customary to prepare a dialysis solution necessary for the dialysis process immediately before dialysis treatment. For this purpose, a solid dialysis concentrate is contained in the container, and this solid dialysate is usually in the form of a powder, a fine granule or a tablet, that is, a powder obtained by crushing a tablet.

  In order to make a dialysate, the solid dialysis concentrate must be dissolved in water. For this purpose, the container containing the solid dialysis concentrate is fixed to a dialysis machine, and the dialysis concentrate solution is usually introduced into the container on one side and drained again on the other side. As a result, there arises a problem that the discharged solution is not saturated and the composition of the dialysate changes.

  It is an object of the present invention to provide a container that reliably saturates a solution prepared for dialysis treatment even when extremely low solubility components are used.

According to the present invention, the above object is achieved by disposing both the inlet and the outlet at the bottom of the container in a suspended state, assuming a known container. In addition, the container has one or more partition walls, thereby forming different individual regions communicating with the inlet and the outlet, and the partition includes at least a fluid between the individual regions. Is available for distribution. In such a configuration, the fluid flows from the inlet, flows through the solid dialysis concentrate at the bottom of the container, partially dissolves the dialysis concentrate, and then reaches the outlet before the fluid reaches the outlet. It passes through an intricate path in the container and dissolves it again through the dialysis concentrate at the bottom of the container. Here, it is essential to place both the inlet and the outlet in the vicinity of the solid dialysis concentrate. This ensures that fresh water flows around the solid dialysis concentrate particles and contributes to the fastest possible dissolution by the resulting turbulence and vortex generation. Positioning the outlet on the same side as the inlet ensures that the liquid has the maximum possible residence time in the undissolved dialysis concentrate, even in continuous operation, resulting in a low solubility salt. In this case, saturation of the solution can be realized. With such a configuration, it is possible to compensate for the density difference.

  US Pat. No. 5,385,564 describes a solution that introduces water through a connection into a container containing granular dialysis concentrate. However, it is first necessary to completely introduce this water into the container, and after the concentrate has been properly dissolved in the water, the completed dialysate must be drained again through the same opening in the container. Such a solution makes continuous operation impossible.

  Preferred embodiments of the invention are derived from subordinate claims following the main claim.

  Therefore, the container of the present invention has an inlet and an outlet formed at the bottom thereof, and is advantageously configured in the form of a bag formed by two films welded together. The inlet and outlet are preferably configured in the form of a connection that can be connected to a dialysis machine.

  It is particularly advantageous to provide filters with holes of 50 μm to 500 μm at both the inlet and the outlet.

In the present container, when the container is formed of a bag in which the side walls of the bag are welded to each other at an appropriate position where the partition is formed, the partition can be formed particularly easily.

  When the dialysis concentrate contains sodium bicarbonate or sodium chloride among various components, the container can be used particularly advantageously.

  Hereinafter, the details and advantages of the present invention will be described in more detail based on the embodiments shown in the drawings.

In the reference form shown in FIG. 1, the container 10 is constituted by a bag made of two plastic films welded to each other on both sides. An inlet 12 and an outlet 14 are provided at the bottom of the bag 10. In the reference form shown here, these inlet 12 and outlet 14 are configured as tubular connections, and the corresponding tube ends 16, 18 (see FIG. 2a) are connected to these connections. Each can be attached by pressing. The lower part of the bag contains a dialysis concentrate 20 made of powder, fine granules, tablets and / or combinations thereof. The bag 10 has two container openings 22 at the upper end thereof, and the bag can be suspended by these. The inlet 12 and the outlet 14 have holes of 50 μm to 500 μm, and can each be provided with a filter 24 that can be inserted into the tube. These filters 24 are also shown in the cross-sectional view of FIG. 2a.

  FIG. 2 shows how water flows in through the inlet 12. In particular, the arrows in the figure show how the fluid flows through the dialysis concentrate along a relatively wide path and is disturbed due to this flow and the concentration difference between the highly concentrated and low concentrated solutions. The flow is shown. This water must flow again through the entire layer of dialysis concentrate from the top of the bag and then be discharged from the outlet 14 in a saturated state. Filter 24 prevents any undissolved dialysis concentrate from flowing into tubing 16 and / or 18.

  Various embodiments of the container 10 of the present invention configured in the form of a bag will be described with reference to FIGS. The shape of the bag is simple, but the shape is not necessarily defined in the present invention.

FIG. 3 is a cross-sectional view corresponding to the reference embodiment shown in FIGS. 1 and 2. The most simplified reference embodiment is different from the embodiment shown in FIGS. 4 to 8 in that the partition wall 26 is provided inside the bag and forms different individual areas in the bag. is there. As a result, a complex path of fresh water flowing through the dialysis concentrate layer is formed.

  FIG. 4 shows a septum 26 between the inlet 12 and the outlet 14 that substantially serves to prevent the formation of a short circuit path between the inlet and the outlet. In the embodiment shown in FIG. 5, the inlet and the outlet are also shown at the lower end of the bag, but two partial regions having greatly different dimensions are formed in the bag. However, basically, these partial areas can also be rotated 180 °. Also in this case, the injection port is located in a narrower region corresponding to the injection port. Such a septum configuration ensures that fresh water is introduced into the area of the dialysis concentrate containing solids and passes through the concentrate before the saturated solution is discharged from the outlet 14. To do.

  FIG. 6 shows two symmetrical chambers 28, 30 formed by the partition wall 26.

  FIG. 7 basically corresponds to FIG. 5 and shows a bag that can be used similarly to the bag of FIG. Here, the long chamber is simply formed by another partition 27 in the bag, and an inlet corresponding to the outlet 14 is formed. This chamber is formed even longer in the embodiment shown in FIG. In the embodiment shown in FIGS. 5 to 8, each bag is formed in a triangular shape toward one side. Such a shape is particularly suitable when the bag is rotated 180 ° compared to the drawings shown here. The reason for this is that undissolved dialysis concentrate accumulates in the tip region of the triangular portion, i.e. in the lower region of the bag, but the corresponding chamber configuration formed by the septum ensures that liquid also flows into this region of the bag. Because it flows.

  Finally, FIG. 9 is a graph showing that a constant saturation concentration can be achieved when the temperature is kept constant during the preparation of dialysate. Here, the saturation state of the solution is calculated by measuring the conductivity. Here, a constant conductivity of about 60 mS / cm at a constant temperature slightly above 28 ° C. under the condition that the dialysate is measured over an appropriate period at the outlet 14 configured as shown in FIG. Has been measured.

It is the schematic which shows the reference form of this invention. It is a figure which shows a mode that water is introduce | transduced in the bag of FIG. FIG. 3 is a partially enlarged view of FIG. 2. It is sectional drawing which simplifies and shows another reference form of this invention. It is sectional drawing which simplifies and shows embodiment of this invention. It is sectional drawing which simplifies and shows another embodiment of this invention. It is sectional drawing which simplifies and shows another embodiment of this invention. It is sectional drawing which simplifies and shows another embodiment of this invention. It is sectional drawing which simplifies and shows another embodiment of this invention. FIG. 6 is a graph showing the temperature of the liquid as a function of time.

Claims (5)

Dialysis that has a water inlet and a discharge port that can be connected to a dialysis machine, and has a hanging part consisting of an opening, and contains a certain amount of dialysis concentrate in the form of powder, fine granules, tablets, or a combination thereof. A container for
Both the inlet and the outlet are arranged on the bottom side of the container where the dialysis concentrate is collected by its own weight when the container is suspended by the suspension part , and in the vicinity of the solid dialysis concentrate. It is located,
The container has one or more partition walls in its interior, thereby forming different individual areas communicating with the inlet and outlet in the container,
The partition wall at least allows fluid to flow between the individual regions,
Before the fluid that has flowed in from the inlet flows through the dialysis concentrate at the bottom of the container and partially dissolves the dialysis concentrate between the individual regions by the partition wall, before reaching the discharge port A dialysis container characterized in that a fluid flow is formed so as to pass through the dialysis concentrate at the bottom of the container again and further dissolve the dialysis concentrate . The dialysis container according to claim 1,
It consists of a bag formed by two films that are welded together,
The aforementioned bottom, dialysis container, wherein a connection portion forming the inlet and the outlet is located. In the dialysis container according to claim 1 or 2,
A dialysis container, wherein a filter having a hole of 50 μm to 500 μm is arranged at each of the inlet and / or the outlet. The dialysis container according to claim 1 ,
When the said container is comprised with the bag, the said partition is formed by welding the plastic membrane which forms the side wall of the said bag mutually, The dialysis container characterized by the above-mentioned. In the dialysis container according to any one of claims 1 to 4 ,
A dialysis container containing bicarbonate or sodium chloride.

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