JP3994048B2 - Composition kit for replica creation - Google Patents

Description

【００１７】
＜実施例２＞
実施例１のレプリカ作成用のキットを用いて、素人の人がレプリカ作成するのにどの程度困難があるかを調べた。即ち、レプリカ作成経験のない人を無作為に２０名選んで、レプリカ作成用のキットを渡し、自分の頬部の皮膚のレプリカを作成してもらった。同時に従来のレプリカ剤でも同様に作成してもらった。回収したレプリカを顕微鏡観察して、実施例１の基準で判定した。結果を表２に出現例数として示す。これより、本発明のキットを用いることにより、素人でも確度高く、品質の高いレプリカが作成できることがわかる。
【００１８】
【表２】

【００１９】
＜実施例３〜６＞
組成物（Ａ）の油脂の量を変えて、レプリカの出来具合を観察した。評価項目は、実施例１同様固化時間と転写のし具合とした。又、収縮の有無も同時に観察した。結果を表３に示す。これより、１気圧２５℃で液体の油脂成分を５〜２０重量％含有することが好ましいことがわかる。（Ｂ）の組成物、（Ａ）の製法、レプリカの製法は実施例１に同じ。
（Ａ）
イ
流動パラフィン ＊ 重量部
水添パーム油 ４ 重量部
ＰＯＥ（４０）フィトステロール ２ 重量部
ソルビタンモノオレート １．５ 重量部
ＰＯＥ（２０）ソルビタンジオレート ６ 重量部
ロ
１，３−ブタンジオール ７ 重量部
二酸化チタン ２．３ 重量部
アルギン酸ナトリウム ２ 重量部
水 ７７．２−＊ 重量部
＊表３に記す。
【００２０】
【表３】

【００２１】
【発明の効果】
本発明によれば、塗布時は液状乃至は軟ペースト状であって、硬化時間が短いレプリカ剤を提供することができる。
【図面の簡単な説明】
【図１】 実施例１の本発明のキット１を用いて作成したレプリカを示す図である。（図面代用写真）
【図２】 実施例１の従来の方法で作成したレプリカを示す図である。（図面代用写真）[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a kit of a composition for making a replica that captures the shape of the surface of the skin.
[0002]
[Prior art]
An important matter when selecting cosmetics is to accurately grasp the properties of the skin. As such means for analyzing skin properties, it is already known that analysis of sebum secretion amount, skin surface shape, keratinocyte shape, etc. is an effective method. Among these, the surface shape of the skin reflects the degree of influence of an aging state and ultraviolet rays, and is known to contain very important information. (JP 2002-165777, JP 2000-342556, JP 2000-315257) Usually, the so-called replica method is used to measure the surface shape of such skin. Originally, the replica method was to partially dissolve the surface of a transparent resin plate such as vinyl chloride with a solvent such as ethyl acetate, and press this onto the skin to copy the irregularities on the surface of the skin. Since the dissolution time is extremely short and the level of dissolution is uneven, various improvements have been made. Examples of such improvements include, for example, a technique for eliminating unevenness using a solution of a water-soluble polymer (Japanese Patent Laid-Open Nos. 01-250223, 01-250334, 04-22340, 05-317292, 10 -101518), a technique using curable silicone (JP-A-11-169453), a technique using a polymer emulsion such as alkyl acrylate (JP-A-11-314416), and the like. Among these, the technique described in JP-A No. 05-317292 is particularly excellent in that the undulating structure of the skin can be faithfully transferred. However, these all made great progress in terms of improving unevenness, but it took 10 to 20 minutes to harden, and during this time, sometimes contact with the skin could occur during this period. If nobody did it, the problem could be over 10%, and there was room for improvement. In other words, it has been desired to develop a replica agent that is liquid or soft paste at the time of application and has a short curing time.
[0003]
On the other hand, with regard to calcium alginate, the so-called “Algepack” technology is known, in which calcium alginate is deposited at the time of use to form a film and used as a pack material. However, there is no example in which this film-forming property is applied to a replica agent (JP 2002-255579, JP 2002-241220, JP 2002-327554). Therefore, it has not been known at all that such a film formation technique is useful for replica production.
[0004]
[Problems to be solved by the invention]
The present invention has been made under such circumstances, and an object of the present invention is to provide a replica agent which is liquid or soft paste at the time of application and has a short curing time.
[0005]
[Means for solving problems]
In view of such circumstances, the present inventors have sought for a replica agent that is liquid or soft paste at the time of application and has a short curing time, and as a result of earnest research efforts, the shape of the surface of the skin A composition kit for making a replica for copying at least two compositions: 1) a composition comprising alginic acid and / or a water-soluble salt thereof; and 2) a composition comprising a water-soluble salt of an alkaline earth metal. Such a characteristic is found in a replica agent kit having a composition as a constituent element, and wherein the at least two compositions are held without being mixed with each other in a state before use and mixed at the time of use. The present invention has been completed. That is, the present invention relates to the following technique.
(1) A kit of a composition for making a replica that captures the shape of the skin surface, comprising 1) a composition containing alginic acid and / or a water-soluble salt thereof, and 2) a water-soluble salt of an alkaline earth metal. It is characterized in that at least two compositions of the containing composition are used as constituents, and the at least two compositions are held without being mixed with each other in a state before use and mixed and used at the time of use. A composition kit for replicating skin.
(2) The composition kit for replicating a skin according to (1), wherein the water-soluble salt of the alkaline earth metal is calcium chloride.
(3) The content of alginic acid and its water-soluble salt is 0.5 to 5% by weight of the total amount in the form immediately before use in which the at least two compositions are mixed, and the water-soluble salt of alkaline earth metal The composition kit according to (1) or (2), characterized in that the content of is 0.2 to 5% by weight of the total amount .
(4) The oil or fat component that is liquid at 1 atm. 25 ° C. is further contained in either or both of the at least two compositions in a total amount of 5 to 20% by weight based on the total amount of the composition after mixing. The composition kit according to any one of (1) to (3).
[0006]
DETAILED DESCRIPTION OF THE INVENTION
(1) Composition containing alginic acid and / or water-soluble salt which is a component of the replica preparation kit of the present invention The replica preparation kit of the present invention comprises a composition containing alginic acid and / or its water-soluble salt. It is a component. Examples of the water-soluble salts of alginic acid, as long as it dissolves in water exhibits liquid particular limitation is not, for example, sodium salts, alkali metal salts, ammonium salts such as potassium salt, triethylamine salt, triethanolamine Examples include organic amine salts such as amine salts, and basic amino acid salts such as arginine salts and lysine salts, but it is particularly preferable to use alkali metal salts of alginic acid, especially sodium salts, in terms of water solubility and stability. . Alginic acid and a salt thereof can be used in combination of two or more. In such a case, a combination with a sodium salt is preferable, and a sodium salt is particularly preferably used alone. In the kit for producing a replica of the present invention, such alginic acid and / or a water-soluble salt thereof has a function of forming a pair with an alkaline earth metal salt to form a water-insoluble film. Such a coating captures the surface shape of the skin. In order to exert such action, it is preferable that alginic acid and its water-soluble salt are contained in a mixed form in an amount of 0.5 to 5% by weight, more preferably 0.7 to 3% by weight of the total amount. . This is because if the amount is too small, the coating may be weak, and if it is too large, the coating may become brittle. None of these are preferred as replica agents.
[0007]
In the composition containing alginic acid and / or a water-soluble salt that is a component of the replica making kit of the present invention, in addition to the above essential components, optional components usually used in replica agents, or pack cosmetics, etc. Optional components used in the film-forming composition can be contained within a range not impairing the effects of the present invention. Examples of such optional components include hydrocarbons such as squalane, liquid paraffin, light liquid isoparaffin, heavy liquid isoparaffin, microcrystalline wax, and solid paraffin, dimethicone, femethicone, cyclomethicone, amodimethicone, polyether-modified silicone, and the like. Silicones, jojoba oil, carnauba wax, mole, beeswax, geiwa, octyldodecyl oleate, isopropyl myristate, neopentyl glycol diisostearate, malate diisostearate, stearic acid, lauric acid, Fatty acids such as myristic acid, palmitic acid, isostearic acid, isopalmitic acid, behenic acid, oleic acid, behenyl alcohol, cetanol, oleyl alcohol, octadecyl alcohol High alcohols such as coal, castor oil, coconut oil, hydrogenated coconut oil, coconut oil, wheat germ oil, triglycerides such as isostearic acid triglyceride, isooctanoic acid triglyceride, olive oil, 1,3-butanediol, glycerin, diglycerin , Dipropylene glycol, polyethylene glycol, 1,2-pentanediol, 1,2-hexylene glycol, isoprene glycol and other polyhydric alcohols, sorbitan sesquioleate, sorbitan monooleate, sorbitan trioleate, sorbitan sesquistearate, sorbitan mono Stearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene stearate, polyoxyethylene oleate, polio Shi ethylene glyceryl fatty esters, polio alkoxy polyoxyethylene alkyl ether, nonionic surfactants such as polyoxyethylene hydrogenated castor oil, sodium lauryl stearate, polyoxyethylene alkyl sulfates, anionic surfactants such as sulfosuccinic acid ester salt Cationic surfactants such as quaternary alkyl ammonium salts, amphoteric surfactants such as alkyl betaines, organic powders such as crystalline cellulose, cross-linked methylpolysiloxane, polyethylene powder, acrylic resin powder, talc, mica , Sericite, magnesium carbonate, calcium carbonate, titanium dioxide, iron oxide, bitumen, ultramarine, titanium mica, titanium sericite, silica and other surface-treated powders, acrylic acid / alkyl methacrylate copolymers and / or Or its salt, carboxybi Nyl polymers and / or salts thereof, thickeners such as xanthan gum and hydroxypropyl cellulose, vitamins such as retinol, retinoic acid, tocopherol, riboflavin, pyridoxine, ascorbic acid, ascorbic acid phosphate ester, glycyrrhizinate, glycyrrhetin, ursolic acid , Terpenes such as oleanolic acid, active ingredients such as steroids such as estradiol, ethinyl estradiol, estriol, preservatives such as phenoxyethanol, parabens, hibiten gluconate, benzalkonium chloride, dimethylaminobenzoic acid esters, cinnamon Preferred examples include ultraviolet absorbers such as acid esters and benzophenones. In the replica kit of the present invention, the composition (A) is preferably in the form of a liquid or a soft paste at the time of application in order to produce a high-quality replica with high accuracy. Such properties can be adjusted by the amount of water added.
[0008]
(2) Composition containing water-soluble salt of alkaline earth metal that is a component of the replica preparation kit of the present invention The replica preparation kit of the present invention comprises a composition containing a water-soluble salt of alkaline earth metal It is contained as an element. Preferred examples of the alkaline earth metal include calcium, barium and magnesium, and preferred salts thereof include chlorides and nitrates, and chlorides are preferred from the viewpoint of versatility. Such an alkaline earth metal salt may contain only one species, or may contain two or more species in combination. In the kit for making a replica of the present invention, the content of the water-soluble salt of alkaline earth metal is 0.2 to 5% by weight, more preferably 0, in the form immediately before use after mixing. It is preferable to contain 4 to 3% by weight. This is because if the amount is too small, the coating may be weak, and if it is too large, the coating may become brittle. None of these are preferred as replica agents. Furthermore, the alginic acid and / or its water-soluble salt and the water-soluble salt of the alkali metal must be kept in contact with each other before mixing.
[0009]
In the composition containing the water-soluble salt of alkaline earth metal that is a constituent element of the replica preparation kit of the present invention, as with the composition containing alginic acid and / or water-soluble salt, in addition to the above essential components, usually a replica agent In the range which does not impair the effect of this invention, the arbitrary components used by film-forming compositions, such as pack cosmetics, or the arbitrary components used by 1 can be contained. Specific examples of such optional components include those similar to the optional components in the composition containing a water-soluble salt of an alkaline earth metal.
[0010]
(3) Replica Creation Kit of the Present Invention The replica creation kit of the present invention is characterized by containing the above-described two essential components as components. As a preferable form in the replica making kit of the present invention, in the form of the final replica making stage, 5 to 20 % by weight, more preferably 10 to 18% by weight of a liquid fat component at 1 atm and 25 ° C. %. In order to make such a form, the oil component is contained in the composition of the essential constituents described in (1) or (2), or is an independent composition as a third constituent, In the replica creation stage, mixing at the time of use is mentioned, and any of these forms may be used. Particularly preferred is a form that is contained in the composition (1) together with a surfactant. As the surfactant used in such a case, in consideration of safety and dispersibility of the oil component, a nonionic surfactant such as POE alkyl ether type, POE sorbitan fatty acid ester type or sorbitan fatty acid ester type should be used. Is preferred. The preferable content of such a nonionic surfactant is 2 to 15% by weight, and more preferably 4 to 10% by weight in the final form. By containing such a fat and a surfactant, it is possible to suppress the destruction of the replica during peeling and to suppress the shrinkage of the replica over time.
[0011]
In order to create a replica using the replica creation kit of the present invention, it is preferable to follow the following procedure. That is,
1) If desired, a composition comprising other optional components is added to the composition of (1), mixed uniformly, and this is applied to the skin on which a replica is to be made. At the time of application, it is applied so as to be uniform with a thickness of about 0.05 to 0.3 mm.
2) The composition of (2) is uniformly applied from above to the application surface of 1). For such application, it is preferable to preliminarily fill the spray container with the composition (2).
3) Let stand for 1 to 3 minutes, confirm solidification, and peel off slowly from the edge.
In this operation, it should be noted that the solidification time is as extremely short as 1 to 3 minutes, and that an observable replica can be obtained without any trouble even when operated by an inexperienced amateur.
[0012]
【Example】
Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.
[0013]
<Example 1>
The compositions (A) and (B) shown below were prepared, (A) was filled in a tube, (B) was filled in a spray bottle, and the kit 1 for making replicas of the present invention was obtained. At the same time, a replica agent using a water-soluble polymer, which is a conventional technique as shown in the following formula, was prepared, and the preparation of the replica was compared. The replica was prepared using a specialized paneler, and the time required for replica creation and the degree of transfer of the replica replica skin structure (ease of confirming the detailed structure) were measured or determined. Judgment of the degree of transfer of the skin structure of the replica (ease of confirming the detailed structure) is made by observing the replica with an optical microscope, ◎: very fine part can be observed, ◯: almost fine structure can be observed, Δ: A large structure can be observed, but a fine portion cannot be observed. The results are shown in Table 1. It can be seen that by using the kit of the present invention, a highly accurate replica specimen can be produced in a short time. FIG. 1 shows a photomicrograph of a replica specimen prepared using the replica preparation kit of the present invention, and FIG. 2 shows a conventional example.
[0014]
<Kit for replica creation of the present invention>
(A)
A liquid paraffin 18 parts by weight hydrogenated palm oil 4 parts by weight POE (40) phytosterol 2 parts by weight sorbitan monooleate 1.5 parts by weight POE (20) sorbitandiolate 6 parts by weight ro 1,3-butanediol 7 parts by weight dioxide Titanium 2.3 parts by weight Sodium alginate 2 parts by weight Water 59.2 parts by weight Manufacturing method)
B) Heat to 80 ° C and mix well to be uniform. A creamy composition was obtained by slowly adding to the mixture with stirring and cooling with stirring. This was packed in a tube and used as the component (A) of the kit.
(B)
Calcium chloride 2 parts by weight citric acid 0.01 parts by weight sodium citrate 0.1 parts by weight water 97.89 parts by weight)
The formulation components were mixed well at room temperature and solubilized to obtain a liquid composition. This was packed in a spray bottle and used as the component (B) of the kit.
Create replica)
1 g of the composition of (A) was applied, and then 0.5 ml of the composition of (B) was sprayed, waited until the surface solidified, this time was measured and peeled to obtain a replica.
[0015]
<Conventional replica agent>
Ibengara 0.01 parts by weight Titanium dioxide 7 parts by weight 1,3-butanediol 2 parts by weight Water 26.685 parts by weight Polyvinyl alcohol 4 parts by weight Ha POE (20) sorbitan monostearate 0.8 parts by weight sorbitan monooleate 0 0.2 parts by weight stearic acid 0.2 parts by weight liquid paraffin 7 parts by weight d-δ-tocopherol 0.005 parts by weight Nipolyvinyl acetate solution 5 parts by weight foethanol 5 parts by weight POE (8) POP (55) 1 part by weight hekaolin 38 parts by weight manufacturing method)
Each component of A, B, and C is separately adjusted to 80 ° C, mixed with components of A and B, cooled to 40 ° C, and then added with components D, E, and F. A replica agent was used.
Create replica)
A replica agent (1.5 g) was applied, waited until the whole solidified, this time was measured, and peeled to obtain a replica.
[0016]
[Table 1]

[0017]
<Example 2>
Using the replica creation kit of Example 1, it was examined how difficult it is for an amateur person to create a replica. In other words, 20 people who had no replica creation experience were randomly selected, and a replica creation kit was handed over to create a skin replica of their own cheeks. At the same time, a conventional replica agent was prepared in the same manner. The recovered replica was observed with a microscope and judged according to the criteria of Example 1. The results are shown in Table 2 as the number of appearance examples. From this, it can be seen that by using the kit of the present invention, even an amateur can make a replica with high accuracy and high quality.
[0018]
[Table 2]

[0019]
<Examples 3 to 6 >
The amount of oil in the composition (A) was changed and the quality of the replica was observed. The evaluation items were solidification time and transfer condition as in Example 1. The presence or absence of shrinkage was also observed at the same time. The results are shown in Table 3. From this, it can be seen that it is preferable to contain 5 to 20 % by weight of a liquid fat component at 1 atm. The composition of (B), the production method of (A), and the production method of the replica are the same as in Example 1.
(A)
A liquid paraffin * parts by weight hydrogenated palm oil 4 parts by weight POE (40) phytosterol 2 parts by weight sorbitan monooleate 1.5 parts by weight POE (20) sorbitan diolate 6 parts by weight ro 1,3-butanediol 7 parts by weight dioxide Titanium 2.3 parts by weight Sodium alginate 2 parts by weight Water 77.2- * parts by weight * Indicated in Table 3.
[0020]
[Table 3]

[0021]
【The invention's effect】
According to the present invention, it is possible to provide a replica agent which is liquid or soft paste at the time of application and has a short curing time.
[Brief description of the drawings]
FIG. 1 is a view showing a replica produced using a kit 1 of the present invention of Example 1. FIG. (Drawing substitute photo)
2 is a view showing a replica created by a conventional method of Example 1. FIG. (Drawing substitute photo)

Claims (4)

A kit of a composition for making a replica that captures the shape of the surface of the skin, comprising 1) a composition containing alginic acid and / or a water-soluble salt thereof, and 2) a composition containing a water-soluble salt of an alkaline earth metal A skin component, characterized in that at least two compositions are used as constituents, and the at least two compositions are used without being mixed with each other in a state before use, and mixed and used at the time of use. A composition kit for making replicas. The composition kit for replicating skin according to claim 1, wherein the water-soluble salt of the alkaline earth metal is calcium chloride. The content of alginic acid and its water-soluble salt is 0.5 to 5% by weight of the total amount in the form immediately before use in which the at least two compositions are mixed, and the content of the water-soluble salt of alkaline earth metal The composition kit according to claim 1 or 2, characterized in that is 0.2 to 5% by weight of the total amount . The oil or fat component that is liquid at 1 atm. 25 ° C. is further contained in either or both of the at least two compositions in a total amount of 5 to 20% by weight with respect to the total amount of the composition after mixing . The composition kit according to any one of claims 1 to 3.

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