JP3814395B2 - Sample collection device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a sample collection device that can easily perform sample collection, separation storage, test identification, and the like in clinical tests, medical biological research fields, agricultural and forestry aquatic product research fields, and tests. It is.
[0002]
[Prior art]
Conventionally, as a sample collection device, a cotton swab, a wooden ladle, a matchstick, a toothpick, a glass rod, a synthetic resin molded product, a brush, a brush, and the like are used depending on the sample.
[0003]
In a synthetic resin molded product that collects a small amount and a very small amount of specimen, grooves, holes, or irregularities are formed, or a small diameter cylindrical shape is formed, and the specimen is placed in the irregularities or small diameter holes.
[0004]
In addition, in cotton swabs, brushes, brushes, etc., a specimen is placed between the fibers.
[0005]
[Problems to be solved by the invention]
The above-described conventional instrument has a drawback that the specimen is not easily separated from the instrument when the collected specimen is dissolved in the lysis solution. Although it is separated naturally, this does not provide sufficient lysis, and even if a small amount of sample is collected accurately, the original purpose may not be achieved.
[0006]
Moreover, when taking out the solution from the instrument, a filter medium may be passed to separate insoluble matters, but there is a problem of clogging due to the limited area of the filter medium. Therefore, it was impossible to take out the device, and the device itself had to be discarded, and it had to be collected again. Re-collecting was not only inefficient, but also remarkably impaired reproducibility when collecting samples.
[0007]
Furthermore, since the conventional collection device collects the specimen itself in the form of fractionation, it has a disadvantage that is unsuitable for collecting a small amount of specimen.
Therefore, the conventional sampling device has not been fully satisfactory.
[0008]
The present invention has been made paying attention to such points, and provides a sample collection device that can easily dissolve a sample in a lysis solution, increase a filtration area, and prevent clogging. Objective.
[0009]
[Means for Solving the Problems]
The configuration of the present invention in accordance with the above object comprises a sample collecting part formed of a material having air permeability and a pump part connected to the collecting part directly or via a connecting pipe, and has been collected and adhered. It is characterized in that the specimen can be peeled and dissolved in the solution by the air compressed by the pump unit.
[0010]
The solution in which the sample is dissolved passes through the sample collection unit having a filtration function, and is aspirated and indwelled in the pump unit, and the discharge unit formed in the pump unit is opened to take out the filtered solution. Forming.
[0011]
DETAILED DESCRIPTION OF THE INVENTION
Next, embodiments of the present invention will be described with reference to the drawings.
The embodiment shown in the figure is an example of a stool collection container used for mass screening for colorectal cancer.
[0012]
As shown in FIG. 1, the sample collector 5 includes a pump unit 1 formed in a cylindrical shape from an elastic material, a small-diameter cylindrical body 2 connected to the pump unit 1, and a tip of the cylindrical body 2. The mounted specimen collecting unit 3 and the container unit 4 that fits tightly into the tightly fitting part (screw part or convex shape) formed in the cylindrical body 2 are configured.
[0013]
The pump unit 1 is made of rubber or soft plastic that can be squeezed to discharge air and inflated to suck air.
[0014]
In the above embodiment, the small-diameter cylindrical body (connecting tube) 2 is tightly fitted and welded to the pump unit 1, but it may of course be formed integrally. In the above-described embodiment, the large-diameter cylindrical body 10 is connected to the rear end of the small-diameter cylindrical body, and the pump unit 1 is tightly fitted to the cylindrical body 10.
[0015]
The material of the specimen collection unit 3 may be any material as long as it has air permeability, water insolubility and sufficient strength, such as open-cell foam, sintered plastic, sintered ceramic, and the like.
[0016]
As a material of the sample collection unit 3, a material having a sorting and filtering function is particularly preferable. For example, it is preferable to select a porosity, rigidity, chemical treatment, and the like of the above-mentioned open-celled foam to give a selective filtering function according to the purpose of use.
[0017]
The shape of the collection unit 3 may be formed in various appropriate shapes according to the properties of the sample to be collected.
Since the collection unit 3 of the present invention is breathable, it can suck and entangle a liquid sample, and can select the inside and outside of the solidified sample by selecting the hardness and shape of the collection unit 3. .
[0018]
The specimen collector 5 is in a tightly plugged (tightly fitted) state by fitting or screwing the container part (cap) 6. By forming in this way, the solution can be indwelled by tightly fitting the container portion 6 after sucking a predetermined amount of the solution into the pump portion 1.
[0019]
In the above embodiment, the container portion 6 is formed so as to be tightly fitted to the threaded portion or the ridge 8 formed on the connecting pipe 5, but this need not be the case as long as the container can be sealed.
[0020]
As shown in FIG. 2, the container 6 is preferably filled with a dissolving solution in advance. However, as shown in FIG. 1, the container 6 is simply used as a cap for hygiene protection of the sample collection unit 3 and dissolved when used. You may make it fill with a liquid.
[0021]
The sample collection unit 3 is integrally connected to the connection unit 2 by press fitting. The connection means is not particularly limited as long as it can withstand pressure increase / decrease by the pump unit 1.
[0022]
A small-diameter pipe-shaped dripping portion 9 is formed at the other end of the pump portion 1. The tip of the dropping unit 9 is cut or perforated, and the solution placed in the pump unit 1 is dropped.
[0023]
Needless to say, the dripping portion 9 may be simply formed in a thin portion and perforated to open.
[0024]
Next, a method of using the sample collecting device of the present invention configured as described above will be described. First, as shown in FIG. 3, holding the pump unit 1 by hand, the sample collecting unit 3 is stabbed into a sample (feces in this embodiment) or the sample surface is rubbed. In the case of liquid stool, it is absorbed on the surface.
[0025]
Next, as shown in FIG. A sample adheres to the sample collection unit, but the excess sample is wiped off with paper or the like.
[0026]
Then, the lid body 6 is pulled out from the mouth portion 7 of the container portion 4 in which the lysis solution is accommodated as shown in FIG. 2, and the sample collector 5 is inserted from the mouth portion 7 of the container portion 4 as shown in FIG.
[0027]
As shown in FIGS. 6 and 7, the pump unit 1 is repeatedly squeezed and opened while the sample collection unit 3 is immersed in the solution. The sample peeled off together with the air by squeezing is dissolved in the dissolving solution, and the liquid in which the sample is dissolved is released by being opened and filtered by the sample collecting unit 3 and sucked into the pump unit 1.
[0028]
When a sufficient amount of sample is inhaled into the pump unit 1, the container unit 4 is tightly fitted or screwed into the sealing plug (screw or convex) 8 of the sample collector 5 as shown in FIG. Seal. Usually, as a stool collection container, it is not necessary to reopen the sealed part, so the sealing means is not particularly limited as long as it can be sealed.
[0029]
Next, the tip of the dropping unit 9 is cut and opened, and is inverted as shown in FIG. 9, and a required amount of solution is dropped onto the reaction paper.
[0030]
According to the present invention, the specimen adhering to the collection unit is peeled into the solution together with the air compressed by the pump unit, so that the pressurized air is discharged as bubbles in the solution, and the sample is removed. Since the sample is stirred, it is easy to dissolve the sample and is suitable for collecting a small amount.
[0031]
Further, according to the present invention, since the sample collection part also serves as a filtering material, it is possible to increase the filtration area and to prevent clogging.
Furthermore, even in the case of a sample that is easily clogged, peeling and suction are repeated by repeatedly pressing and releasing the pump part, so that a sufficient amount of solution can be placed in the pump part.
[0032]
The sample collection device of the present invention can be used not only as a sample collection device but also as a storage container, a culture container, a transport container, or the like provided with the sample collection device.
[0033]
【The invention's effect】
As described above, according to the present invention, the specimen can be very easily dissolved in the lysis solution, and there is a remarkable effect that is not found in this kind of conventional collection instrument that clogging does not occur during filtration. .
[0034]
[Brief description of the drawings]
FIG. 1 is a partial cross-sectional view showing an embodiment of the present invention.
FIG. 2 is a cross-sectional view of the container portion of the present invention.
FIG. 3 is a cross-sectional view showing a state in which a sample is collected using the collection instrument of the present invention.
FIG. 4 is a cross-sectional view showing a state in which the collection instrument of the present invention is pulled up from a specimen.
FIG. 5 is a cross-sectional view showing a state in which the collection part of the present invention is immersed in a solution.
FIG. 6 is a cross-sectional view illustrating a state in which a specimen is peeled by squeezing a pump unit.
FIG. 7 is a cross-sectional view showing a state in which a pump is opened and a sample is inhaled.
FIG. 8 is a cross-sectional view showing a state in which a solution is sucked and placed in the pump unit.
FIG. 9 is a cross-sectional view showing a state where a dropping part is opened and a solution is dropped.
[Explanation of symbols]
1 Pump part 2 Connection part (connection pipe)
3 Sample collection part 4 Container part (cap)
5 Sample collector

Claims (6)

An air sample comprising a sample collection part formed of a material having air permeability and a pump part connected to the collection part directly or via a connecting pipe, and the sample collected and adhered is compressed by the pump part Thus, the specimen collecting device is configured so that it can be peeled and dissolved in the solution. The instrument according to claim 1, wherein the sample collection unit is formed to have a sorting and filtering function. The solution in which the sample is dissolved is sucked and placed in the pump unit through the sample collection unit having a filtration function, and the discharge unit formed in the pump unit is opened to take out the filtered solution. The device according to claim 2, wherein the device is formed as follows. The solution is stored in a cylindrical container closed at one end, and the cylindrical container is formed so that a predetermined amount of the solution is sucked into the pump part and then tightly fitted to the connecting pipe or the pump part. The instrument of claim 3. The pump part is formed in a cylindrical body whose one end is closed, and is formed so as to inhale air by pressing and deforming the cylindrical body to push out air and releasing the pressure to return to the original shape. The instrument of claim 4 comprising: A storage container, a culture container, or a transport container provided with the sample collection device according to any one of claims 1 to 5.

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