JP3583508B2 - Sample dispensing system by container and sample dispensing method by container - Google Patents

Description

[0001]
[Industrial applications]
The present invention relates to a container-specific sample dispensing system and a container-specific sample dispensing method for dispensing a sample from an original container into a dispensing container for testing components in the sample such as blood, plasma, and serum. Things.
[0002]
[Prior art]
Samples such as blood, plasma, and serum collected at each medical institution are placed in an original sample container (generally, a test tube container with a diameter of 10 mm to 16 mm), and a label indicating a sample number for identifying the sample is displayed. Is sent to the sample laboratory. On the other hand, a sample test request form in which test items and the like are entered is also sent to the sample laboratory, and the entered test instruction information is input to the host computer.
[0003]
The host computer sets the test number of the sample according to the test instruction information of the sample, and outputs a test number label including the sample number and the test number. Further, after calculating and storing the position information of each sample on the sample container rack on which the sample is set, a test instruction for each sample including the sample position information and the test number is output.
[0004]
The above-described test number label is attached by an operator to a sample container to which the sample number displayed on the label is attached. Thereafter, the sample containers are arranged on a sample container rack in accordance with the sample position information in the order of the test numbers assigned to the sample containers.
[0005]
The sample container rack in which the samples are sorted and arranged is set in a precision dispenser by an operator. The precision dispenser performs a sample dispensing operation based on a test number and sample position information received from a host computer or the like, and performs a test using an automatic analyzer or the like that stores the sample position information.
[0006]
The test result of the sample thus obtained is sent to the host computer, output as a report, and sent to the test orderer.
[0007]
[Problems to be solved by the invention]
However, when the operator sets the sample container rack in which the samples are sorted and aligned in the precision dispenser, at the same time, the dispensing amount and the like determined in advance corresponding to the type of the sample container and the test item are determined. Had to be keyed. Therefore, when setting the sample container rack, the operator identifies the type of the sample container rack, and furthermore, tests items to be performed on the samples stored in the sample container rack, It is necessary to recognize the order and the amount of the sample to be dispensed necessary for performing this test and to make a key input, thereby complicating the operation. In addition, although the above-mentioned operation is performed with the utmost care, the type of the sample container rack may be erroneously recognized, and an error may occur when keying data. .
[0008]
An object of the present invention is to provide a container-specific sample dispensing system and a container-specific sample dispensing method for dispensing a sample into a dispensing container of a type determined according to a test item by a predetermined amount. That is.
[0009]
[Means for Solving the Problems]
The container-specific sample dispensing system according to claim 1, A parent sample rack having a plurality of sample holding units and having a storage medium for storing, for each parent sample, a test item to be performed on each parent sample held by these sample holding units; and storage of the parent sample rack. Inspection items read from the medium Test item storage means for storing each parent sample in association with the sample number, and type and dispensing container for dispensing the parent sample for performing each test item in accordance with each test item Container information storage means for storing dispensing container information for each type, test item reading means for reading out test items to be performed on parent specimens to be dispensed from test item storage means, and container information storage means. Dispensing container information reading means for reading dispensing container information corresponding to the type of dispensing container stored corresponding to the inspection item read by the inspection item reading means; A dispensing hole position calculating means for calculating a dispensing hole position of the dispensing container based on the read dispensing container information, and a dispensing hole at the dispensing hole position calculated by the dispensing hole position calculating means. Parent sample to be injected Characterized in that it comprises a dispensing Note means.
[0011]
Claims 2 The sample dispensing system for each container described in the claim 1 The container-specific sample dispensing system described above is further characterized by further comprising a dispensing result storing means for storing a dispensing result of the parent sample by the dispensing means in association with a sample number for each parent sample.
[0012]
Claims 3 The sample dispensing system for each container described in the claim 1 The container-specific sample dispensing system described above further includes a dispensing result writing unit that writes a dispensing result of the parent sample by the dispensing unit to a storage medium of the parent sample rack.
[0013]
Claims 4 The sample dispensing system for each container described in the claim 2 Or claims 3 The described dispensing result of the container-specific sample dispensing system includes position information of a hole in the dispensing container that holds the dispensed child sample.
[0015]
Claims 5 The container-specific sample dispensing method described above is directed to a parent sample having a plurality of sample holding units, and a storage medium for storing, for each parent sample, a test item performed on each parent sample held by the sample holding unit. A first step of reading test items to be performed for each parent sample from the storage medium of the rack; and a test item to be performed for each parent sample read in the first step. A second step of storing in the test item storage means in association with the number, a type of a dispensing container for dispensing a parent sample for performing each test item corresponding to each test item, and a type of the dispensing container A third step of storing dispensing container information for each container in the container information storage means, and a third step of reading out the test items stored in the second step, which are to be performed on the parent sample to be dispensed, from the test item storage means. Step 4 and Step 4 To flop Than A fifth step of reading the dispensing container information of the type of the dispensing container stored corresponding to the read inspection item from the container information storage means, and a dispensing container read by the fifth step A sixth step of calculating the dispensing hole position of the dispensing container based on the information, and a seventh step of dispensing a parent sample to be dispensed into the dispensing hole at the dispensing hole position calculated by the sixth step. And the step of:
[0016]
[Action]
According to the container-specific sample dispensing system of the first aspect, the test item reading means reads out the test item to be performed for the parent sample to be dispensed from the test item storage means, and the test container information reading means. Then, the dispensing container information of the type of the dispensing container stored corresponding to the inspection item read by the inspection item reading unit is read from the container information storage unit. The dispensing hole position calculating means calculates the dispensing hole position of the dispensing container based on the dispensing container information read by the dispensing container information reading means. The dispensing means dispenses the parent sample to be dispensed to the dispensing hole at the dispensing hole position calculated by the dispensing hole position calculating means.
[0017]
Therefore, the parent sample can be dispensed to a dispensing container of a type determined corresponding to the test item to be performed on the parent sample, that is, a dispensing container having a different size or shape.
[0018]
Claims 1 According to the container-specific sample dispensing system described above, the test items to be performed for each parent sample are read from the storage medium of the parent sample rack and stored in the test item storage means, so that the test items are executed for each parent sample. Inspection items can be stored without error.
[0019]
Claims 2 According to the container-specific sample dispensing system described in the above, since the dispensing result of the parent sample by the dispensing means is stored in association with the sample number for each parent sample, the dispensing result can be used for the sample test. it can.
[0020]
Claims 3 According to the container-specific sample dispensing system described above, the dispensing result of the parent sample by the dispensing means is written to the storage medium of the parent sample rack, so that the dispensing result is obtained only from the storage medium of the parent sample rack without accessing the host system. Note You can know the result.
[0021]
Claims 4 According to the described container-specific sample dispensing system, since the dispensing result includes the position information of the hole in the dispensing container holding the dispensed child sample, the sample is inspected based on the hole position information. be able to.
[0023]
Claims 5 According to the container-specific sample dispensing method described above, the test items to be performed for each parent sample are read from the storage medium of the parent sample rack, and the test items are stored in association with the sample numbers for each parent sample. In addition, the test items performed on each parent sample can be stored without error.
[0024]
【Example】
Hereinafter, embodiments of the present invention will be described with reference to the drawings.
[0025]
FIG. 1 is a diagram for explaining a layout of a sample dispensing system installation room 1 in which a sample dispensing system is installed. The sample dispensing system installation room 1 is provided with a sample loading / unloading port 2 through which a parent sample 25 is loaded on a wagon and loaded or unloaded.
[0026]
Further, the sample dispensing system installation room 1 is provided with a carry-in specimen waiting area 3 where the carry-in parent specimen 25 is put on the specimen carry-in wagon 3a and waits until the carry-in parent specimen 25 is put into the pre-dispensing step. Further, there is provided a pre-dispensing processing area 4 in which pre-dispensing processing steps such as thawing and stirring are performed on the parent sample 25. In the pre-dispensing process area 4, a thawing machine 4a and a stirrer 4b are installed, and a pre-dispensing work table 4c is installed.
[0027]
Further, a rack assembling process area 5 in which a rack assembling process is performed is provided adjacent to the pre-dispensing process area 4. The rack assembling area 5 is provided with a rack assembling apparatus 5a in which a worker performs a rack assembling step.
[0028]
Note that, between the pre-dispensing process area 4 and the rack assembling process area 5, an automatic transport vehicle for transporting the parent specimen 25, for which the pre-dispensing process has been completed, to the rack assembling process is running. A carrier traveling path 6 is provided. In addition, a rack transport conveyor 5b for transporting the parent sample 25, for which the rack assembly process has been completed, to the dispensing area 7 for dispensing is provided in front of the rack assembling apparatus 5a.
[0029]
FIG. 2 is a diagram for explaining the details of the dispensing area 7. In the dispensing area 7, a rack insertion device 7a is installed in contact with the rack transport conveyor 5b. Downstream of the rack transport conveyor 5b in the dispensing area 7, a section dispensing unit F in which the quantity determination dispensing unit 7b and the section dispensing unit 7c are installed and a pre-dispensing unit in which the pre-dispensing unit 7d is installed. G is provided.
[0030]
Here, section dispensing is dispensing that does not require quantitative accuracy (coarse dispensing), and pre-dispensing is dispensing that requires quantitative accuracy (precision dispensing).
[0031]
The parent sample 25 to be dispensed in each section dispensing unit 7c and the pre-dispensing unit 7d is determined in advance based on the test items performed on the parent sample 25.
[0032]
In addition, the section dispensing section F is provided with a rack retraction device 7e for retracting a rack transport conveyor 5b of the section dispensing section F and a parent sample rack with bar code (hereinafter, parent sample rack with BC) 26, At the end of the rack transport conveyor 5b of the section dispensing section F and the pre-dispensing section G, a rack discharge device 7f is provided.
[0033]
Further, in the sample dispensing system installation room 1, a parent sample temporary storage area 8 for temporarily storing a parent sample 25, a holding process area 10 for performing a holding process, and a parent sample 25 for which dispensing has been completed are stored in a sample. In order to carry out the sample from the dispensing system installation room 1, there is provided an unloading sample waiting area 11 which is placed on a sample unloading wagon 11 a and waits.
[0034]
FIG. 3 is a block diagram for explaining the configuration of a computer system that controls the dispensing system.
[0035]
In the figure, a reference numeral 15 denotes a basic host computer, which controls the dispensing system and a receiving system for receiving a parent sample 25 dispensed by the dispensing system. In the figure, the reference numeral 16 denotes a dispensing host computer, which controls the entire dispensing system.
[0036]
The dispensing host computer 16 is connected via a connection cable 30 to the main host computer 15 which is a host computer. In addition, the dispensing host computer 16 is connected to the dispensing pre-processing management computer 17, the rack assembly device management computer 18, the rack input device management computer 19, the rack pull-in device management computer 20, and the Note: The unit management computer 21 and the rack ejection device management computer 22 are connected.
[0037]
Here, the pre-dispensing processing management computer 17 is used for the work of the pre-dispensing processing step, and is installed on each pre-dispensing processing worktable 4c. The rack assembly apparatus management computer 18 controls the rack assembly apparatus 5a, and is installed near each rack assembly apparatus 5a. The rack input device management computer 19 controls writing of data to a data carrier (hereinafter, referred to as DC) 28 by the rack input device 7a, and is installed close to the rack input device 7a. The rack retraction device management computer 20 controls a rack retraction device 7e that pulls the parent sample rack with BC 26 transported by the transport conveyor 5b into the transport conveyor 5c in which the section dispensing unit 7c is installed. .
[0038]
Further, the dispensing unit management computer 21 controls the quantity determining dispensing unit 7b, the section dispensing unit 7c, and the pre-dispensing unit 7d, and is installed close to each dispensing unit 7b, 7c, 7d. I have. The rack discharge device management computer 22 controls the discharge of the rack by the rack discharge device 7f, and is installed near the rack discharge device 7f.
[0039]
The dispensing host computer 16 can also input data from the wireless terminal 23.
[0040]
Next, with reference to FIGS. 4 to 9, a pre-dispensing process management computer 17, a rack assembly device management computer 18, a rack input device management computer 19, a rack pull-in device management computer 20, a dispensing unit management computer 21, and a rack discharge. Each configuration of the device management computer 22 will be described.
[0041]
FIG. 4 is a block diagram showing a configuration of the pre-dispensing process management computer 17. The pre-dispensing process management computer 17 includes a CPU 17a for controlling the entire pre-dispensing process management computer 17. The CPU 17a is connected to a key input unit 17b, a storage unit 17c, a barcode reader (hereinafter, referred to as BCR) 17d, and a label issuing unit 17e. The key input unit 17b is provided with a numeric keypad (not shown) for inputting a sample number. Further, the storage unit 17c stores character data and the like for issuing a sample number. Further, the BCR 17d reads a barcode attached to the parent sample 25, and the label issuing unit 17e issues a label displaying the same sample number as the sample number read by the BCR 17d. It is.
[0042]
FIG. 5 is a block diagram showing a configuration of the rack assembly apparatus management computer 18. The rack assembly device management computer 18 includes a CPU 18a for controlling the entire rack assembly device management computer 18. A key input unit 18b, a storage unit 18c, a self-propelled BCR 18d, a beam sensor 18e, and a buzzer 18f are connected to the CPU 18a. The key input section 18b includes a bar code reading start key (START key of the key input section 18b in FIG. 17) attached to the parent sample 25, and the like. The storage unit 18c stores a sample number, dispensing information for each sample, and the like. Further, the self-propelled BCR 18d reads a bar code attached to the parent sample 25, and the beam sensor 18e detects a position of the parent sample 25 from which the bar code is read. The buzzer 18f generates an alarm sound when the beam sensor 18e detects an error in the position of the parent sample 25.
[0043]
FIG. 6 is a block diagram showing a configuration of the rack input device management computer 19. The rack input device management computer 19 includes a CPU 19a for controlling the entire rack input device management computer 19. A data carrier reader / writer (hereinafter, referred to as DCRW) 19b, a BCR 19c, and a storage unit 19d are connected to the CPU 19a. The DCRW 19b writes the sample number and the dispensing information for each sample in the DC. The storage unit 19d stores the sample number written into the DC 28 by the DCRW 19b, dispensing information for each sample, and the like.
[0044]
FIG. 7 is a block diagram showing a configuration of the rack pull-in device management computer 20. The rack retraction device management computer 20 includes a CPU 20a for controlling the entire rack retraction device management computer 20. A data carrier reader (hereinafter, referred to as DCR) 20b is connected to the CPU 20a, and a parent sample rack with BC is provided based on a sample number and dispensing information for each sample stored in the DC 28 read by the DCR 20b. It is determined whether 26 is drawn into the transport line 5b in which the section dispenser 7c is installed.
[0045]
FIG. 8 is a block diagram showing a configuration of the dispensing processing unit management computer 21. The dispensing processing unit management computer 21 includes a CPU 21a for controlling the entire dispensing processing unit management computer 21. The DCRW 21b, the storage unit 21c, and the BCR 21d are connected to the CPU 21a. The DCRW 21b reads the dispensing information stored in the DC 28 and writes the result of the dispensing to the DC 28. The storage unit 21c stores dispensing information read from the DC 28.
[0046]
FIG. 9 is a block diagram showing a configuration of the rack discharge device management computer 22. The rack discharge device management computer 22 is provided with a CPU 22a for controlling the entire rack discharge device management computer 22. The BCR 22b, the DCRW 22c, and the storage unit 22d are connected to the CPU 22a. The BCR 22b reads a rack number assigned to a sample rack, and the DCRW 22c reads dispensing information stored in the DC. In addition, the dispensing information read from the DC 28 is stored in the storage unit 22d.
[0047]
Next, processing steps of the dispensing system will be described with reference to the drawings.
[0048]
FIG. 10 is a flowchart for explaining the outline of the dispensing process. The parent sample 25 is loaded on the sample loading wagon 3a and is loaded into the sample dispensing system installation room 1 from the sample loading / unloading port 2 (S1). In addition, the parent sample 25 requested to be retested from each test room is also carried into the sample dispensing system installation room 1 (S2). The carried-in parent sample 25 is made to wait in the carried-in sample waiting area 3 until it is put into the pre-dispensing process. The parent sample 25 taken out of the carry-in sample waiting area 3 is subjected to pre-dispensing processing in the pre-dispensing processing area 4 (S3). The parent sample 25 for which the pre-dispensing process has been completed is transported to the rack assembly process area 5 by the automatic transport vehicle. In the rack assembling process area 5, a rack assembling process for transferring 50 parent samples 25 to the parent sample rack 26 with BC is performed (S4).
[0049]
The parent sample 25 placed on the BC-added parent sample rack 26 is transported to the dispensing area 7 by the transport conveyor 5b and subjected to dispensing line processing (S5). In this dispensing line process, a process of attaching the DC 28 to the parent sample rack 26 with BC and writing dispensing information is performed, and an empty rack supply process of supplying the dispensing child sample rack 27 to the dispensing units 7c and 7d. (S5a), the parent sample rack 26 with BC is drawn into the dispensing units 7c and 7d based on the storage information of the DC 28 mounted on the parent sample rack with BC transported by the transport conveyor 5b, and the parent sample 25 is dispensed. The dispensing process to be performed (S5b) is performed. In addition, the parent sample 25 with the error at the time of dispensing is extracted from the parent sample rack with BC 26, and the abnormal parent sample withdrawal process (S5c) is transferred to the holding process (S6). A parent specimen storage process (S5d) of storing the storage sample in the storage wagon 55 to generate storage information is also performed.
[0050]
The parent sample 25 extracted by the above-described abnormal parent sample extraction process (S5c) is carried to the suspension process area 10 and the suspension process (S6) is performed. When the error is released by the suspension processing, the rack assembly processing (S4) is performed, and the rack assembly processing (S5) is performed again.
[0051]
The dispensed child sample rack 27 is stored in the sample unloading wagon 11a in the unloading sample waiting area 11, and the unloading process is performed (S7).
[0052]
Next, a configuration of the parent sample rack with BC 26 (sample rack) used in the dispensing system of this embodiment will be described with reference to FIGS.
[0053]
The parent sample rack with BC 26 has a rectangular bottom plate 70, a side wall 71 extending in the transport direction is provided on the bottom plate 70, a front wall 72 is provided at a front end of the bottom plate 70, and a rear wall 72 is provided at a rear end thereof. A rear wall 73 is provided. Nine partition walls 74 are provided at equal intervals between the front wall 72 and the rear wall 73, and one end of the partition wall 74 is in contact with the side wall 71. Five recesses are formed in the inner wall surfaces 72a, 73a of the front wall 72 and the rear wall 73, and both wall surfaces 74a of the partition wall 74, and are provided to face the recesses of the front wall 72 and the recesses. The concave portion of the partition wall 74, the concave portion of the partition wall 74, the concave portion of the adjacent partition wall 74 provided opposite to the concave portion, the concave portion of the partition wall 74, and the rear wall 73 provided opposite to the concave portion. The concave portions form fifty sample holders 75 (five rows, ten rows in the transport direction).
[0054]
Further, on the upper surfaces of the front wall 72, the rear wall 73, and the partition wall 74 forming each of the sample holding sections 75, a resin piece 76 for positioning the parent sample 25 held by the sample holding section 75 is provided with a metal plate 77. Is screwed through. The resin piece 76 allows the parent sample 25 to be held at the center of the sample holding unit 75 even when the thickness of the sample held by the sample holding unit 75 is different.
[0055]
In addition, a storage medium holding unit 80 is provided on the outer wall surface of the side wall 71 described above. The storage medium holding section 80 has L-shaped grooves 80a on the left and right and on the bottom, and holds both ends and the bottom of the DC 28 by the grooves 80a. The DC 28 can be removed from the storage medium holding unit 80 by sliding the DC 28 upward.
[0056]
Therefore, when the DC 28 is defective, the DC 28 can be easily replaced. Further, since the storage medium holding section 80 is provided on the side wall 71, the dispensing information can be easily read and written to the DC 28 of the parent sample rack with BC 26 transported by the transport conveyor 5b.
[0057]
Further, a bar code 81 is displayed on the outer wall surface of the side wall 71. This bar code 81 indicates the rack number of the parent sample rack 26 with BC.
[0058]
The above-mentioned DC has a rectangular shape with a predetermined thickness, and has a built-in SRAM and a battery for holding data. Writing and reading of data to and from the DC 28 can be performed by DCRW in a non-contact manner.
[0059]
Next, each processing of the above-mentioned dispensing process will be described in detail with reference to FIGS.
[0060]
First, the pre-dispensing process (S3 in FIG. 10) will be described with reference to FIG. The parent sample 25 subjected to the dispensing process is carried into the sample dispensing system installation room 1 (S10). For the loaded parent sample 25, the number of the loaded sample racks and the loading slip are checked (S11).
[0061]
Next, when the parent specimen 25 is a defrosted specimen that requires cryopreservation of the specimen due to the characteristics of the examination item, the thawing start time for each examination item is displayed as to whether it is time to thaw. A check is made on the timetable, and if it cannot be thawed, it is returned to a predetermined position (S12). If the parent sample 25 can be thawed, it is immersed in the water bath of the thawing machine 4a and thawed for every 50 racks carried in (S13). The thawed parent sample 25 is stirred by the stirrer 4b (S14). Note that, in the case of a normally stored sample that does not require cryopreservation of the sample due to the characteristics of the test items, thawing is not necessary, and thus only stirring (S14) is performed.
[0062]
Next, the sample amount is checked by visual inspection, and it is determined whether or not the container is the eighth minute or more of the parent sample 25 (S15). If it is determined that the sample volume is equal to or less than the eighth minute of the container of the parent sample 25, the presence or absence of fibrin is checked (S16), and if there is fibrin, it is removed (S17). Next, it is checked whether or not the parent sample 25 is not hemolyzed or not milky (S18). If the parent sample 25 is hemolyzed or milky, the information is stored in the pre-dispensing management computer. By operating the keys of the 17 key input unit 17b, an input is made to the dispensing pre-processing management computer 17 (S19). Thereafter, the parent sample 25 is transferred to the wire mesh rack 29 (S31).
[0063]
On the other hand, when the sample amount is determined to be equal to or longer than the eighth minute of the container of the parent sample 25 in the processing of S15, the sample number of the parent sample 25 is read by the BCR 17d of the pre-dispensing processing management computer 17, and the label is read. The issuing unit 17e issues a label displaying the same sample number (S20). The issued label is attached to another sample container (S21).
[0064]
Next, the cap of the sample container of the parent sample 25 is cut off (S22), the presence or absence of fibrin is checked (S23), and if there is fibrin, it is removed (S24). Next, it is checked whether the parent sample 25 is not hemolyzed or not milky (S25). If the parent sample 25 is hemolyzed or milky, the information is stored in the pre-dispensing management computer. 17 (S26).
[0065]
Thereafter, the sample of the parent sample 25 is subdivided into the sample container to which the label displaying the same sample number is attached so that the sample container remains for about 8 minutes (S27).
[0066]
After this processing, the parent sample 25 is transferred to the wire mesh rack 29 (S31). The divided sample containers are stored together with the parent sample 25 after the dispensing process of the parent sample 25 is completed (S29, S30).
[0067]
Next, the rack assembly process (S4 in FIG. 10) will be described with reference to FIGS. At the time when the rack assembly process is started, the sample information for each sample stored in the basic host computer 15 (see FIG. 14), that is, the basic information (the test item, the test item stored corresponding to the sample number, The basic information of the information such as materials) and the patient information (information such as the patient name, gender, and age stored in correspondence with the sample number (number unique to the sample)) is stored in the dispensing host computer 16 as dispensing information. It is input and stored (see FIG. 15).
[0068]
First, the configuration of the rack assembly device 5a will be described with reference to FIG. The rack assembly apparatus 5a is provided with a rack mounting table 90 for mounting the parent sample rack with BC 26. The rack mounting table 90 is provided with four sets of beam sensors 18e. That is, when the parent sample rack with BC 26 is mounted, one set of beam sensors is provided at both ends of each of the sample holding unit rows in the B row, the C row, the D row, and the E row of the parent sample rack with BC 26. 18e. The rack assembly device 5a includes a self-propelled BCR 18d that reciprocates along a guide rail 91 installed along a side piece of the rack mounting table 90. The self-propelled BCR 18d reciprocates along a guide rail 91 by a stepping motor (not shown) and a belt (not shown).
[0069]
Further, the rack assembling apparatus 5a is provided with a key input section 18b having a START key, an END key, and the like.
[0070]
Next, the rack assembly processing shown in FIG. 16 will be described. First, the parent sample 25 placed on the wire mesh rack 29 and conveyed from the pre-dispensing process is picked up (S400). Next, the parent samples 25 are aligned in units of ten on the parent sample rack with BC 26 set on the rack mounting table 90 of the rack assembly apparatus 5a (S401). That is, first, ten parent samples 25 are aligned in row A of the parent sample rack with BC 26 shown in FIG.
[0071]
Thereafter, when an instruction to read the barcode 81 is given by operating the START key of the key input unit 18b (S402), it is determined whether or not the ten parent samples 25 are correctly set in the row A of the parent sample rack with BC 26. Is detected (S403). That is, since the position of the parent sample 25 set in the parent sample rack with BC 26 is monitored by the beam sensor 18e, when the parent sample 25 is not detected by the beam sensor 18e, the position of the parent sample rack 26 with BC is determined. It is determined that the parent sample 25 is correctly set in the row A, and the process proceeds to S405.
[0072]
On the other hand, when the parent sample 25 is detected by the beam sensor 18e, it is determined that the parent sample 25 is erroneously set in a row other than the row A of the BC-added parent sample rack 26, and the buzzer 18f emits a buzzer sound. When it is generated, an alarm is issued to the worker (S404). In this case, the operator correctly sets the parent sample 25 in the row A of the parent sample rack with BC 26, and again gives an instruction to read the barcode 81 by operating the START key of the key input unit 18b. .
[0073]
If it is determined that the parent sample 25 is correctly set in the row A of the parent sample rack with BC 26 in the process of S403 described above, the self-propelled BCR attaches the parent sample 25 to the side wall of the parent sample rack with BC 18d. The rack number of the parent sample rack with BC 26 is read by reading the bar code 81 (S405). Here, when the rack number cannot be read, the parent sample rack with BC 26 is replaced (S406, S407).
[0074]
Next, the sample numbers of the 10 parent samples 25 arranged in row A of the parent sample rack with BC 26 are read by the self-propelled BCR 18d (S408). Thereby, the position on the BC-added parent sample rack 26 where the sample is set is detected. That is, the position of the sample on the parent sample rack with BC 26 depending on which of the sample holding unit rows in the rows A to E holds the sample whose sample number is read, and the number of the sample in the sample holding unit row. Is detected. The detected position of the sample (rack number and hole number) is stored in the storage unit 18c in association with the sample number (S409).
[0075]
Next, it is determined whether or not the reading of the BCs of the parent sample 25 has been completed for the sample holding unit rows of the B, C, D, and E columns of the parent sample rack 26 with BC (S410). If the processing has not been completed, the parent samples 25 are arranged in the order of row B, row C, row D, and row E in the parent sample rack 26 with BC, and the same processing is performed. That is, ten parent samples 25 are aligned in the B row of the parent sample rack with BC 26 (S411). Thereafter, when a reading instruction of the bar code 81 is given by operating the START key of the key input unit 18b (S412), it is determined whether the ten parent samples 25 are correctly set in the row B of the parent sample rack 26 with BC. Is detected (S413).
[0076]
That is, since the position of the parent sample 25 set in the parent sample rack with BC 26 is detected by the beam sensor 18e, the parent sample 25 is detected by the beam sensor 18e at a position corresponding to the row B of the parent sample rack with BC 26. If not detected, it is determined that the parent sample 25 is not correctly set in the row B of the parent sample rack with BC 26, and a buzzer 18f generates a buzzer sound to warn the operator (S414). . In this case, the operator correctly sets the parent sample 25 in the row B of the parent sample rack 26 with BC, and again gives an instruction to read the barcode 81 by operating the START key of the key input unit 18b. .
[0077]
Note that the parent samples 25 are also aligned in rows C, D, and E of the parent sample rack 26 with BC, and the same processing is performed (S408 to S414). When the reading of the sample numbers of all the parent samples 25 set in the parent sample rack 26 with BC is completed (S410), the rack number and the hole number corresponding to the sample numbers stored in the storage unit 18c are dispensed. Sent to host computer 16. As a result, the dispensing information stored in the dispensing host computer 16 is such that the sample number is associated with the parent rack number, the parent rack hole number, and the inspection item / dispensing amount (see FIG. 18).
[0078]
Next, the dispensing line processing (S5 in FIG. 10) will be described with reference to FIG.
[0079]
First, the dispensing information is written in the DC 28 of the parent sample rack 26 with BC (S50). That is, as shown in FIGS. 20 and 21, when the parent sample rack with BC 26 transported by the transport conveyor 5b from the rack assembling process arrives at the rack insertion device 7a, the rack number of the parent sample rack with BC 26 is obtained by the BCR 19c. Is read (S65, S65). Next, the dispensing information (see FIG. 18) of the sample contained in the parent sample rack with BC 26 of this rack number is transferred from the dispensing host computer 16 to the rack loading device management computer 19, and is transferred to the DC 28 by the DCRW 19b. It is written (S67). After the writing of the dispensing information in the DC 28 is completed, the parent sample rack with BC 26 is transported to the dispensing unit groups 7b, 7c, 7d by the transport conveyor 5b.
[0080]
Next, the transport route of the parent sample rack with BC 26 in the dispensing area 7 will be described with reference to FIGS.
[0081]
When the parent sample rack with BC 26 in which the writing of the dispensing information has been completed in the DC 28 in the rack input device 7a is transported to the rack retraction device 7e by the transport conveyor 5b, the DCR 20b (see FIG. 7) is used. The order information is read and the section dispensing (coarse dispensing) section F determines whether or not the parent sample 25 for section dispensing exists in the parent sample rack with BC 26. If it is determined that the parent sample 25 for section dispensing exists in the parent sample rack with BC 26, a branch instruction is issued by the CPU 20a, and the parent sample rack with BC 26 is drawn into the section dispensing unit F. .
[0082]
When the parent sample rack with BC 26 to which the section dispensing has been performed in each section dispensing unit 7c of the section dispensing unit F has been transported to the rack discharge device 7f, it is stored in the DC 28 by the DCR 22c. When the dispensing information is read and the dispensing for all parent samples 25 has been completed, a discharge instruction is issued by the CPU 22a, and the parent sample rack with BC 26 is discharged from the section dispensing unit F.
[0083]
On the other hand, if there is a parent sample 25 for which dispensing processing has not yet been completed, the parent sample 25 is transported to the downstream dispensing unit 7c by the transport conveyor 5b. After the section dispensing, the parent sample rack with BC 26 is transported to the pre-dispensing (precision dispensing) section G. When the parent sample rack with BC 26 pre-dispensed in each pre-dispensing unit 7d of the pre-dispensing unit G is transported to the rack discharge device 7f, the amount stored in the DC 28 by the DCR 22c. When the note information is read and the dispensing for all the parent samples 25 has been completed, a discharge instruction is issued by the CPU 22a and the parent sample rack with BC 26 is discharged from the pre-dispensing unit G.
[0084]
Next, the amount determination dispensing, section dispensing and pre-dispensing performed in the section dispensing unit F and the pre-dispensing unit G will be described. When the parent sample rack with BC 26 is transported by the transport conveyor 5b to the position of the volume determination / dispensing unit 7b, it is determined whether or not to perform the volume determination (S51 in FIG. 19). That is, as shown in FIGS. 24 and 26, the dispensing information stored in the DC 28 of the parent sample rack with BC 26 is read into the CPU 21a (see FIG. 8) by the DCRW 21b (S70). Based on the dispensing information read in here, it is determined whether or not the parent sample 25 for which the volume determination needs to be performed exists in the parent sample rack with BC 26 (S71). If it is determined that there is a parent sample 25 that needs to be determined, it is determined whether or not two BC-added parent sample racks 26 exist in the rack buffer 50 of the dispensing unit 7b. This is performed (S72), when it is determined that the two parent sample racks with BC 26 do not exist, a branch command is output by the CPU 21a (S73), and the parent sample rack with BC 26 is dispensed from the dispensing unit 7b. Drawn into.
[0085]
The determination of the amount of the parent sample 25 stored in the parent sample rack with BC 26 drawn into the dispensing unit 7b is performed based on the control of the dispensing unit management computer 21. That is, it is determined whether or not each of the parent samples 25 needs to be subjected to the amount determination (S74). If it is determined that the sample needs to be determined, the sample is drawn by the dispensing nozzle 51a of the dispenser 51 to determine whether the sample amount is normal (S75, S76), and again. Discharge the sample to the original sample container. If it is determined that the sample amount is not normal by the determination of the sample amount, the information is stored in the storage unit 21c. This process is performed for all 50 samples (S78). After the process is completed, information about the sample whose sample volume is determined to be abnormal is written to the DC 28 by the DCRW 21b, and the parent sample rack with BC 26 is unloaded to the transport conveyor 5b. (S79).
[0086]
The parent sample 25 of the parent sample rack with BC 26 after the volume determination dispensing process is subjected to section dispensing (S54) or pre-dispensing (S55) in the corresponding dispensing units 7c and 7d (see FIG. 19). ).
[0087]
Here, section dispensing (coarse dispensing) will be described with reference to FIGS. When the parent sample rack with BC 26 is transported by the transport conveyor 5b to the position of the section dispensing unit 7c, it is determined whether or not section dispensing is performed by the section dispensing unit 7c. That is, as shown in FIGS. 27 and 29, the dispensing information stored in the DC 28 of the parent sample rack with BC 26 is read into the CPU 21a (see FIG. 8) by the DCRW 21b (S85). Based on the dispensing information read in here, it is determined whether or not there is a parent sample 25 that needs to be section-dispensed by the section dispensing unit 7c in the parent sample rack with BC 26 (see FIG. 4). S86).
[0088]
If it is determined that there is a parent sample 25 that needs to be dispensed, it is determined whether or not two BC-added parent sample racks 26 exist in the rack buffer 50 of the dispensing unit 7c. (S87), when it is determined that the two parent sample racks with BC 26 do not exist, the amount determination dispensing has already been performed on the parent sample 25 of the parent sample rack with BC 26. It is determined whether it has been performed (S88). Here, if it is determined that the quantity determination dispensing has already been performed, a branch command is output by the CPU 21a (S89), and the parent sample rack with BC 26 is drawn into the section dispensing unit 7c.
[0089]
On the other hand, when it is determined that these conditions (S86, S87, S88) are not satisfied, the parent sample rack with BC 26 is transported to the downstream dispenser by the transport conveyor 5b.
[0090]
The section dispensing of the parent sample 25 stored in the BC-added parent sample rack 26 drawn into the section dispensing unit 7c is performed under the control of the dispensing unit management computer 21. That is, it is determined whether or not each of the parent samples 25 requires a section dispensing (S90). Here, if it is determined that the sample needs section dispensing, it is determined whether or not the volume is determined to be normal (S91). If the sample is determined to be empty or the sample amount is not sufficient by the amount determination, the sample is transferred to the holding step (S6 in FIG. 10).
[0091]
On the other hand, in the case of the sample whose volume determination is determined to be normal, the sample is sucked up by the dispensing nozzle 51a of the dispenser 51 (S93), and an appropriate amount of the sample is discharged into the child sample container 32 of the child sample rack 27. (S94). At this point, an examination number (ID-1) is assigned to this sample (S95). Here, the inspection number (ID-1) is a number that is composed of characters and numerals and represents an inspection room, an inspection item, and the like.
[0092]
Next, it is determined whether or not the sample has been dispensed to all the child sample containers 32 of the child sample rack 27 (S96). The sample rack 27 is discharged (S97), and a new child sample rack 27 is supplied (S98). This process is performed on all parent samples 25 for which section dispensing is performed by the section dispenser 7c in the parent sample 25 of the parent sample rack 26 with BC (S99), and the results of dispensing are written to the DC 28. At the same time (S100), the result of the dispensing is transmitted to the dispensing host computer 16 (S101), and the parent sample rack with BC 26 is discharged to the transport conveyor 5b. The discharged parent sample rack with BC 26 is transported by the transport conveyor 5b to the downstream section dispenser 7c.
[0093]
By transmitting the results of dispensing to the dispensing host computer 16 described above, the dispensing host computer 16 stores the test number (ID-1) corresponding to the sample number (ID-0) attached to the sample, and the parent rack. The number, parent rack hole number, child rack number, child rack hole number, and the like are stored (see FIG. 30).
[0094]
The supply of the child sample rack 27 will be described with reference to FIGS. 31 and 32. That is, when it is determined that the sample has been dispensed to all the child sample containers 32 of the child sample rack 27 (S96 in FIG. 28), the CPU 21a of the dispensing unit management computer 21 supplies the child sample rack 27. An instruction is given (S125). Accordingly, the child sample rack 27 is transported from the empty rack stocker 52 by the transport conveyor 53. The rack number (barcode) of the transported child sample rack 27 is read by the BCR 21d (S126) and stored in the storage unit 21c of the dispensing unit management computer 21 (S127).
[0095]
Next, pre-dispensing (precision dispensing) will be described with reference to FIGS. When the parent sample rack with BC 26 is transported by the transport conveyor 5b to the position of the pre-dispensing unit 7d, it is determined whether or not the pre-dispensing unit 7d performs dispensing. That is, as shown in FIGS. 33 and 37, the dispensing information stored in the DC 28 of the parent sample rack with BC 26 by the DCRW 21b is read by the CPU 21a (see FIG. 8) (S105), and stored in the storage unit 21c. You. Based on the read dispensing information, it is determined whether or not there is a parent sample 25 that needs to be dispensed by the pre-dispensing unit 7d in the parent sample rack with BC 26 (S106). . For example, when it is predetermined that the pre-dispensing unit 7d dispense the parent specimen 25 on which the test item X is to be performed (the test item X is performed by the pre-dispensing unit 7d in the following description as well). It is assumed that dispensing is performed for the parent sample 25 in advance.) If the dispensing information read from the DC 28 is as shown in FIG. Since there is a parent sample 25 that performs X, it is determined that there is a parent sample 25 that needs to be dispensed by this pre-dispensing unit 7d.
[0096]
Here, when it is determined that there is a parent sample 25 that needs to be pre-dispensed, it is determined whether or not two BC-added parent sample racks 26 exist in the rack buffer 50 of the dispensing unit 7d. If a determination is made (S107) that it is determined that the two parent sample racks with BC 26 do not exist, a branch command is output by the CPU 21a (S108), and the parent sample rack 26 with BC is placed in this pre-sample rack. It is drawn into the dispensing unit 7d.
[0097]
On the other hand, the parent sample rack with BC 26, which is determined not to satisfy these conditions (S106, S107), is transported to the downstream pre-dispensing unit 7d by the transport conveyor 5b.
[0098]
The pre-dispensing of the parent sample 25 stored in the parent sample rack with BC drawn into the pre-dispensing unit 7d is performed under the control of the dispensing unit management computer 21. That is, the parent sample 25 performs the test item X in order from the hole number 1 of the parent sample rack with BC 26 by referring to the dispensing information (FIG. 38) read from the DC 28 and stored in the storage unit 21c. It is determined whether or not there is (S110).
[0099]
Here, when it is determined that the sample to perform the test item X (in this case, first, the sample of the sample number 10000 is determined to be the sample to perform the test item X), it is determined whether the amount is determined to be normal by the amount determination. Is determined (S111). In the case where the sample is determined to be empty or the sample volume is determined to be insufficient by the volume determination, the sample is transferred to the suspension step (S6 in FIG. 10) (S112).
[0100]
On the other hand, in the case of the sample whose volume determination is determined to be normal, precise dispensing is performed (S113). Here, the precise dispensing will be described with reference to FIG. First, by referring to the dispensing information (FIG. 38) stored in the storage unit 21c, the test item performed on the parent specimen 25 and the predetermined dispensing amount for the test item X can be determined. Read identification (S201). Here, the dispensed amount predetermined for the test item X is the amount of the sample necessary for performing the test item X, that is, χ in this case.
[0101]
Next, by referring to the container / reagent information table 300 (FIG. 39) previously received from the dispensing host computer 16 and stored in the storage unit 21c, the amount stored in correspondence with the test item X is obtained. The type of the injection container is identified (S202). That is, in this case, since the type I of the dispensing container is stored corresponding to the inspection item X, it is identified that the type of the dispensing container is I. In the container / reagent information table 300, for each test item, the type of container used for the test of the test item, the container information (the number of holes for each type of container, the interval between holes on the container, and the dispensing is completed. Information on the hole position and the position of the container on the dispensing unit, etc.) and information on the reagents used in the inspection of the test item (reagent type, reagent dispensing amount, reagent position on the dispensing unit, etc.) are stored. I have.
[0102]
In the description of the section dispensing, the parent specimen 25 is dispensed into the child specimen container 32 of the child specimen rack 27. However, in the pre-dispensing, the parent specimen 25 is placed on a microplate or the like having a plurality of dispensing holes. Are sometimes dispensed, the description will be made as a child sample rack (or dispensing container) 27 and a child sample container (or dispensing hole) 32.
[0103]
Next, the container information is read from the container / reagent information table 300 into the CPU 21a (S203), and the position of the child sample container (or dispensing hole) 32 for dispensing is calculated based on the container information (S204). The CPU 21a outputs a control signal for moving the dispensing nozzle 51a of the dispensing machine 51 to the calculated position of the child sample container (or dispensing hole) 32, and the child for which the dispensing nozzle 51a has been calculated. The sample is moved to the position of the sample container (or dispensing hole) 32, and the amount stored as the dispensed amount of the test item X, that is, the sample of χ is dispensed (S205). Thereafter, the hole number (or the dispensing hole number of the dispensing container) of the child sample rack 27 holding the dispensed child sample container is stored in association with the sample number (S206). Also, by storing the position of the dispensed child sample container (or dispensing hole) 32 in the container information (S207), the position of the dispensed child specimen container (or dispensing hole) 32 is stored. Update information for.
[0104]
When the precise dispensing is completed, the test number (ID-1) and the test item number (ID-3) are numbered (number setting) for this sample (S114). Here, the inspection number (ID-3) is a number composed of numbers indicating the measurement order and the like for each inspection item.
[0105]
Next, it is determined whether or not the sample has been dispensed into all the child sample containers (or dispensing holes) 32 of the child sample rack (or dispensing container) 27 (S115), and all the child sample containers ( If the sample has not been dispensed into the dispensing hole 32, the next parent sample 25 (in this case, the sample with the sample number 10004) for performing the test item X is searched by referring to the dispensing information. Then, the processing such as the above-described precise dispensing is repeated (S110 to S115). Therefore, in the pre-dispensing unit 7d, the samples of the sample numbers 10000, 10004, 10005,... Are precisely dispensed.
[0106]
On the other hand, when dispensing is performed to all the child sample containers (or dispensing holes) 32 of the child sample rack (or dispensing container) 27, reagent dispensing is performed on the child sample rack (or dispensing container) 27. Is performed (S116).
[0107]
That is, as shown in FIG. 36, first, in the processing of S115, the child specimens determined to have finished dispensing all the child specimen containers (or dispensing holes) 32 of the child specimen rack (or dispensing container) 27. The type of the rack (or dispensing container) 27 is identified (S210). The type of the child sample rack (or dispensing container) 27 is identified because the position on the pre-dispensing unit 7d is stored for each type of the child sample rack (or dispensing container) 27. Is performed depending on which sub-sample rack (or dispensing container) 27 is located at the dispensing hole where dispensing has been performed.
[0108]
Next, by referring to the dispensing information and the information stored in the container / reagent table 300, a test item to be performed on the sample in the child sample rack (or dispensing container) 27 is identified (S211). ).
[0109]
Next, the reagent information stored in the container / reagent table 300 corresponding to the test item is read (S212). That is, the type of the reagent to be dispensed, the amount of the reagent, and positional information on the dispensing unit where the reagent is installed are read.
[0110]
Further, the container information stored in correspondence with the type of the child sample rack (or dispensing container) 27 identified in the process of S210 from the container / reagent table 300, that is, the hole position on the container and the container information The position on the note unit is read (S213). The position of the child sample container (or dispensing hole) 32 for dispensing the reagent is calculated based on the container information (S214). The CPU 21a outputs a control signal for moving the dispensing nozzle 51a of the dispenser 51 to the position where the reagent is installed, moves the dispensing nozzle 51a to the position of the reagent, and stores the dispensed amount as the dispensed amount. Aspirate a certain amount of reagent. In addition, a control signal for moving the dispensing nozzle 51a of the dispenser 51 is output to the calculated position of the child sample container (or dispensing hole) 32, the dispensing nozzle 51a is moved, and Is dispensed (S215). Thereafter, the information on the position of the dispensed child specimen container (or dispensing hole) 32 is updated by storing the dispensed hole position in the reagent information (S216). This process is performed for all the child sample containers (or dispensing holes) 32 of the child sample rack (or dispensing container) 27 (S217).
[0111]
After the reagent dispensing is completed, the child sample rack (or dispensing container) 27 is discharged (S117), and a new child sample rack (or dispensing container) 27 is supplied by the above-described processing (FIGS. 31 and 32). (S118).
[0112]
This process is performed on all parent samples 25 to be pre-dispensed by the pre-dispensing machine 7d in the parent sample 25 of the parent sample rack 26 with BC (S119), and the results of dispensing are written to the DC 28. At the same time (S120), the result of dispensing is transmitted to the dispensing host computer 16 (S121), and the parent sample rack with BC 26 is discharged to the transport line 5b. The discharged parent sample rack with BC 26 is transported to the downstream pre-dispensing unit 7d by the transport conveyor 5b.
[0113]
The transmission of the dispensing results to the dispensing host computer 16 described above causes the dispensing host computer 16 to provide the examination number (ID-1) and the examination item number (ID-) corresponding to the sample number (ID-0). 3) The parent rack number, parent rack hole number, child rack number, child rack hole number, and the like are stored (see FIG. 40).
[0114]
The parent sample storage process (S5c in FIG. 10 and S57 in FIG. 19) is performed on the parent sample rack with BC 26 (S56 in FIG. 19) for which section dispensing and pre-dispensing have been completed. That is, as shown in FIGS. 41 and 42, the parent sample rack with BC 26 discharged from the rack discharge device 7f is transferred to the storage wagon 55 (S130). When the parent sample rack with BC 26 has been transferred to all shelves of the storage wagon 55 (S131), the wagon number is read by the wireless terminal 23 and transmitted to the dispensing host computer 16 (S132). Also, all the shelf numbers and rack numbers are transmitted from the wireless terminal 23 to the dispensing host computer 16 (S133, S134). After this process is completed, the storage wagon 55 is stored in the refrigerator.
[0115]
On the other hand, the child sample racks 27 (see FIGS. 29 and 37) discharged from the section dispensing section F and the pre-dispensing section G are carried out from the sample dispensing system installation room 1 and carried into each examination room.
[0116]
【The invention's effect】
According to the container-specific sample dispensing system of the present invention, the dispensing container information calculating means calculates the dispensing hole position of the dispensing container based on the dispensing container information stored for each type of dispensing container, For a dispensing container of a type determined corresponding to the test item to be performed on the parent sample for dispensing to the calculated hole position by the dispensing means, that is, for dispensing containers having different sizes and shapes. The parent sample can be dispensed. In addition, even when a single dispensing unit dispenses a specimen for performing different types of test items, the dispensing operation can be performed efficiently.
[0117]
According to the container-specific sample dispensing method of the present invention, the dispensing hole position of the dispensing container is calculated based on the dispensing container information of the dispensing container type stored for each test item, and the parent sample is dispensed. Is performed, the parent sample can be dispensed to a dispensing container of a type determined in accordance with the test item to be performed on the parent sample.
[Brief description of the drawings]
FIG. 1 is a diagram for explaining a layout of an installation room in which a sample dispensing system is installed.
FIG. 2 is a diagram illustrating details of a dispensing area.
FIG. 3 is a block diagram illustrating a configuration of a computer system that controls the sample dispensing system.
FIG. 4 is a block diagram showing a configuration of a pre-dispensing process management computer.
FIG. 5 is a block diagram illustrating a configuration of a rack assembly apparatus management computer.
FIG. 6 is a block diagram illustrating a configuration of a rack input device management computer.
FIG. 7 is a block diagram illustrating a configuration of a rack retraction device management computer.
FIG. 8 is a block diagram illustrating a configuration of a dispensing processing unit management computer.
FIG. 9 is a block diagram illustrating a configuration of a rack ejection device management computer.
FIG. 10 is a flowchart illustrating an outline of a dispensing process.
FIG. 11 is a perspective view of a parent sample rack with BC.
FIG. 12 is a perspective view of a parent sample rack with BC.
FIG. 13 is a flowchart illustrating a pre-dispensing process.
FIG. 14 is a diagram for explaining sample information for each sample stored in the core host computer.
FIG. 15 is a diagram for explaining dispensing information stored in the dispensing host computer at the start of the rack assembly process.
FIG. 16 is a flowchart illustrating a rack assembling process.
FIG. 17 is a schematic diagram for explaining rack assembling processing.
FIG. 18 is a diagram for explaining dispensing information stored in the dispensing host computer at the end of the rack assembly process.
FIG. 19 is a flowchart illustrating a dispensing line process.
FIG. 20 is a flowchart illustrating DC writing.
FIG. 21 is a schematic diagram for explaining DC writing.
FIG. 22 is a diagram for explaining a transport path of a parent sample rack with BC in a dispensing area.
FIG. 23 is a diagram for explaining a transport path of a parent sample rack with BC in a dispensing area.
FIG. 24 is a flowchart for explaining how a parent sample rack with BC is pulled into a volume determination / dispensing unit.
FIG. 25 is a flowchart for explaining the amount determination / dispensing in the amount determination / dispensing unit.
FIG. 26 is a view for explaining the amount determination / dispensing in the amount determination / dispensing unit.
FIG. 27 is a flowchart for explaining how a parent sample rack with BC is pulled into a section dispensing unit.
FIG. 28 is a flowchart for explaining section dispensing in the section dispensing unit.
FIG. 29 is a diagram for explaining section dispensing in the section dispensing unit.
FIG. 30 is a diagram for explaining information stored in the dispensing host computer corresponding to the sample number after section dispensing.
FIG. 31 is a flowchart illustrating the supply of a child sample rack.
FIG. 32 is a diagram illustrating supply of a child sample rack.
FIG. 33 is a flowchart for explaining how a parent sample rack with BC is pulled into a pre-dispensing unit.
FIG. 34 is a flowchart for explaining pre-dispensing in the pre-dispensing unit.
FIG. 35 is a flowchart for explaining precise dispensing.
FIG. 36 is a flowchart for explaining precise dispensing.
FIG. 37 is a view for explaining pre-dispensing in the pre-dispensing unit.
FIG. 38 is a diagram illustrating a specific example of dispensing information.
FIG. 39 is a diagram for explaining a container / reagent table.
FIG. 40 is a diagram for explaining information stored in the dispensing host computer corresponding to the sample number after pre-dispensing.
FIG. 41 is a flowchart illustrating a storage process of a parent sample.
FIG. 42 is a view for explaining a parent sample storage process;
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 ... Sample dispensing system installation room, 3 ... Loading sample waiting area, 4 ... Pre-dispensing process area, 4c ... Pre-dispensing work table, 5 ... Rack assembly process area, 5a ... Rack assembly apparatus, 5b ... Transport Conveyor, 7: dispensing area, 7a: rack input device, 7b: quantity dispensing unit, 7c: section dispensing unit, 7d: pre-dispensing unit, 7e: rack retraction device, 7f: rack discharge device, 15 ... Main host computer, 16: dispensing host computer, 17: dispensing pre-processing management computer, 18: rack assembly device management computer, 19: rack loading device management computer, 20: rack pull-in device management computer, 21: dispensing unit management Computer, 22: Rack ejection device management computer, 25: Parent sample, 26: Parent sample rack with BC (sample H), 27: child sample rack (or dispensing container), 28: data carrier (DC), 31: child sample, 32: child sample container (or dispensing hole), 50: rack buffer, 51: dispenser , 71 ... side wall, 75 ... sample holding part, 80 ... storage medium holding part.

Claims (5)

A parent sample rack having a plurality of sample holding units and having a storage medium for storing, for each parent sample, a test item to be performed on each parent sample held by these sample holding units;
Test item storage means for storing the test items read from the storage medium of the parent sample rack in association with a sample number for each parent sample;
Corresponding to each test item, a container information storage means for storing a type of a dispensing container for dispensing a parent sample and a dispensing container information for each type of the dispensing container for performing each test item,
Test item reading means for reading test items to be performed on a parent sample to be dispensed from the test item storage means;
Dispensing container information reading means for reading dispensing container information corresponding to the type of dispensing container stored corresponding to the test item read by the test item reading means from the container information storage means;
Dispensing hole position calculating means for calculating a dispensing hole position of the dispensing container based on the dispensing container information read by the dispensing container information reading means,
A dispensing means for dispensing a parent specimen to be dispensed in a dispensing hole at a dispensing hole position calculated by the dispensing hole position calculating means. 2. The sample dispensing system according to claim 1, further comprising: a dispensing result storage unit configured to store a dispensing result of the parent sample by the dispensing unit in association with a sample number for each parent sample. . 2. The sample dispensing system according to claim 1, further comprising: a dispensing result writing unit that writes a dispensing result of the parent sample by the dispensing unit to the storage medium of the parent sample rack. 4. The sample dispensing system according to claim 2, wherein the dispensing result includes position information of a hole in the dispensing container holding the dispensed child sample. Each of the parent samples is stored in a parent sample rack having a plurality of sample holding units and having a storage medium for storing, for each parent sample, a test item to be performed on each parent sample held by the sample holding units. A first step of reading the inspection items performed on
A second step of storing, in the test item storage means, a test item to be performed on each parent sample read in the first step in association with a sample number for each parent sample;
A third type of storing the dispensing container type for dispensing the parent sample and dispensing container information for each dispensing container type in the container information storage means in correspondence with each test item. Steps and
A fourth step of reading, from the test item storage means, a test item stored in the second step, which is performed on a parent sample to be dispensed;
A fifth step of reading, from the container information storage means, the dispensing container information of the type of the dispensing container stored corresponding to the inspection item read in the fourth step;
A sixth step of calculating a dispensing hole position of the dispensing container based on the dispensing container information read in the fifth step;
A seventh step of dispensing the parent sample to be dispensed into the dispensing hole at the dispensing hole position calculated in the sixth step.

Images