JP3144812B2 - Infusion bag - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION The present invention is made of a thermoplastic resin film, and does not leak-mix before use.
The present invention relates to an infusion bag that can be easily and aseptically mixed when used.

[0002]

2. Description of the Related Art In a field where hygiene is required when a chemical solution is used, when two or more types of chemical solutions are mixed and used, if the chemical solutions are mixed and filled into a container from the beginning, there is a risk of reaction or deterioration. Often it has to be mixed just before use.

[0003] At this time, in general, drug solutions are collected and mixed with a syringe, containers filled with the respective drug solutions are communicated with an adapter or the like, or a drug solution contained in each container at the time of use is used as one container. And the like. Therefore, there is a demand for a container that requires a lot of trouble when used, and that can easily and hygienically mix a chemical solution and use it.

As a solution to this problem, a known infusion bag is known which is divided into a plurality of chambers by a partition jig.

As shown in FIG. 5, an infusion bag 1 has a bag portion 3 made by applying a heat seal 2 to a tubular film made of a thermoplastic resin, and a liquid solution filling or taking out portion attached to the bag portion 3. And the mouth member 4 of the above.

When the bag portion 3 of the infusion bag 1 is partitioned liquid-tightly into a plurality of chambers and different chambers are filled with different medicines, for example, as shown in FIGS. Is disposed on one surface of the partitioning portion of the bag portion 3 and the rod 6 is attached to the clamp 5 from the other surface side.
Into a liquid-tight partition by pushing it into the opening 5a.

[0007]

However, the bag 3
Is formed of a cylindrical film, and when this is liquid-tightly partitioned by a partition jig 7 composed of a clamp 5 and a rod 6, annular portions 8 are formed on both side edges as shown in FIG. The annular portion 8 is liable to cause liquid leakage between the chambers even when pressed, and the engaging force of the partition jig 7 must be increased to completely separate the annular portions.

[0008] Since the partition jig 7 is mounted when a chemical solution is filled at a factory, the partition jig 7 can be easily mounted. However, the partition jig 7 is sent to a hospital or the like.
When used, the rod 6 fitted to the clamp 5 cannot be easily removed, which is time-consuming, and is a troublesome task of busy nursing.

Further, in order to prevent the occurrence of liquid leakage between the chambers from both side edges of the bag portion 3, narrow heat seals 9 are applied to both side edges as shown in FIGS. Although the locking force of the jig 7 can be reduced so as not to be performed, even in this case, the locking force of the partitioning jig 7 is considerable in order to prevent leakage between the chambers during transportation. It must be strong, and it takes time to remove the partition jig 7 on site.

The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an infusion bag in which a partition jig can be easily removed, and in which there is little leakage between rooms during transportation.

[0011]

In the infusion bag of the present invention, the width of the bag portion from one side edge to the other side edge in the width direction is changed.
In a straight line, the inner surfaces of the resin films are liquid-tightly divided into a plurality of chambers by a partition band in which the inner surfaces of the resin films are weakly bonded to each other .
Applying an internal pressure of 10 to 100 g / cm ² to one chamber to obtain an adhesive strength for peeling was used as a means for solving the problem.

Since the infusion bag of the present invention is divided into a plurality of parts by a weakly bonded partition band, if no force is applied from the outside, liquid leakage between the chambers does not occur. Since the tool does not need a function of partitioning liquid-tightly, it is only necessary to prevent separation of the partition band, so that leakage between chambers is prevented by the partition jig having a weak engaging force.

The method of weakly adhering the partition band is not limited at all, but for example, a heat and pressure treatment such as a heat seal bar can be used.

[0014] Further, a method of causing blocking in the partition band in high-pressure steam sterilization may be used.

Hereinafter, the present invention will be described in detail with reference to the drawings.

In FIG. 1, reference numeral 11 denotes a partition band which is weakly adhered.
0 g / cm ^2, preferably peeled by adding the internal pressure of 20~60g / cm ^2,, it is desirable that the chamber 12 is communicated.

In the partition strip 11 which peels off when the internal pressure is less than 10 g / cm ² , even if a partition jig is attached, it may peel off during transportation and liquid leakage between chambers may occur. When the internal pressure is 100
In the partition strip 11 which does not peel off unless it exceeds g / cm ² , considerable effort is required to peel it off and connect the chambers 12 with each other. there occurs, there is that liquid leakage to the outside occurs.

The width of the partition 11 is 2 mm or more, especially 3 to
10 mm is preferred. If the width of the partition band is less than 2 mm, even if a weakly engaging partition jig is attached to this portion, a slight peeling will occur, and liquid leakage between the chambers 12 will occur. Further, even if the width exceeds 10 mm, the effect is not changed and the accommodation amount of the chemical solution is reduced, which is uneconomical.

The partition band 11 is formed by heating and pressing the bag portion 3, and its peeling strength is
The type of the resin, the thickness, the width of the partition to be formed, the heating temperature, the pressing force, and the pressing time vary, but only the heating temperature is changed and the other conditions are kept constant to form the partition 11 and shown in FIG. The infusion bag in which the water 14 is filled in the chamber 12 in which the internal pressure gauge 13 is mounted as described above is prepared, and the partition strip 11 is peeled off by a pressurizing device 15 which pressurizes and measures the internal pressure as shown in FIG. When measuring the internal pressure at the time of
The peeling temperature is set at 100 g / cm ² . The partition band 11 formed in this temperature range has good reproducibility and peels off in the range of the internal pressure.

An infusion bag having a heat seal 9 as shown in FIG. 4 also has an internal pressure of 10 to 100 g / cm.
^The partition strip 11 to be peeled at ² can be formed.

[0021]

【Example】

Examples 1 to 3 and Comparative Examples 1 to 5 Using an infusion bag shown in FIG. 1 made of a 250 μm polyethylene cylindrical film, using a heat seal bar, pressing force 4 kg / cm ² , time 1 second, width 5 mm Was formed by changing the temperature, and pressure was applied by a pressurizing device 15 as shown in FIG. 3 to measure the internal pressure at which the partition strip 11 peeled off. Table 1 shows the results. In the table, operability is indicated by ○ when the partition strip is peeled off by lightly pressing the bag portion with one hand, and x when the bag is not easily peeled off by pushing with both hands.

[0022]

[Table 1]

Further, the partition strips of the infusion bags provided with the partition strips of Examples 1 to 3 and Comparative Examples 1 to 5 were clamped by aluminum clamps having an inner diameter of 5.7 mm and fitted with Teflon rods having different diameters. Fixed and pressurized by 2.0
The pressure was increased to kg / cm ² , and the liquid leakage in the chamber 12 was examined. The results are shown in Table 2.

[0024]

[Table 2]

[0025]

As described above, the infusion bag of the present invention is provided with a partition strip which is peeled off at an internal pressure of 10 to 100 g / cm ² and a partition jig is attached to this part. It is not necessary to provide a sealing function, and it suffices to prevent separation of the partition band, and a weak engaging force that can be easily removed is sufficient.

Furthermore, during transportation and the like, there is no liquid leakage due to the interaction between the divider band and the jig. In a use site such as a hospital, the divider band between the rooms can be removed by removing the jig and pressing it lightly by hand. Since they are easily separated and communicated with each other, the drug solution is hygienically mixed without invasion of various bacteria and the like. Therefore, there is an advantage that the labor of busy nurses at the hospital site can be reduced and a large number of patients can be handled.

[Brief description of the drawings]

FIG. 1 is a front view showing one embodiment of an infusion bag according to the present invention.

FIG. 2 is an infusion bag to which an internal pressure gauge for measuring internal pressure is attached.

FIG. 3 is an explanatory diagram of a method of measuring an internal pressure at which a partition strip separates.

FIG. 4 is a front view showing another example of an infusion bag.

FIG. 5 is a front view showing an example of a conventional infusion bag.

6 is a sectional view taken along line VI-VI of FIG. 5;

FIG. 7 is a perspective view showing an example of a conventional partition jig.

FIG. 8 is a side view showing a state where the bag portion is partitioned by a partition jig.

FIG. 9 is a front view showing another example of the conventional infusion bag.

FIG. 10 is a sectional view taken along line XX of FIG. 9;

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Infusion bag 2 Heat seal 3 Bag part 4 Port member 5 Clamp 5a Opening 6 Rod 7 Partition jig 8 Annular part 9 Narrow width heat seal 11 Partition band 12 Partitioned room (room) 13 Internal pressure gauge 14 Water 15 Addition Pressure device

──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-63-309263 (JP, A) JP-A-1-240469 (JP, A) JP-A-2-255148 (JP, A) JP-A-58-1983 183469 (JP, A) Japanese Utility Model Showa 57-105272 (JP, U) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61J 1/05

Claims (3)

(57) [Claims] 1. An infusion bag in which a bag portion formed of a tubular film made of a thermoplastic resin is provided with a mouth member for filling or taking out a chemical solution, wherein the bag portion has one side in the width direction.
Liquid-tightly partitioned into a plurality chambers from the side edge in a straight line to the other side edge of the partition zones inner surfaces is weak adhesion of the resin film, the partition zone, one chamber to 10 to 100 g / cm
^2. An infusion bag characterized by an adhesive strength that is peeled off when an internal pressure is applied. 2. The transfusion bag according to claim 1, wherein both side edges of the bag are heat-sealed to a narrow width. 3. The infusion bag according to claim 1, wherein the weakly bonded partition band is a partition band formed by heating and pressing two resin films in the bag portion.