JP3141612B2 - Organ cannula - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an organ cannula for medical or animal experiments, and more particularly to an organ cannula suitable for an organ deeply located in a body cavity such as the stomach, liver, and pancreas of a ruminant. .

[0002]

2. Description of the Related Art A cannula is a part of an animal body, a digestive tract,
This instrument is inserted into an incision, a blood vessel, an organ, or the like, and is used for injecting a drug solution or discharging secretions and contents.

[0003] The constituent materials of such a cannula include a metal (for example, US Pat. No. 4,096,860) and a plastic (for example, Japanese Patent Application Laid-Open No. 54-142888).
Harlan A. Thyfault, J.M. Dairy
Science, 58 (12) 1899, (197)
5)), polyvinyl chloride or silicone rubber (for example, JP-A-63-150066), polyethylene terephthalate or polyethylene fluoride, and a metal cannula coated with a synthetic substance (JP-A-55-4).
No. 7867), a tube in which polyurethane is fixed to a tube woven of polyester fibers (JP-A-62-53).
No. 54), a product obtained by dipping and curing an epoxy resin in polyurethane (RJ Komark, J. Ani).
mal Science, 53 (3) 790 (198
1)) or silicon resin (RW Douger)
ty, et al. , Canadian J .; Anim
alScience, 68 , 561 (1988)) and the like.

[0004] However, cannulas made of these materials do not simultaneously satisfy vascular adaptability, moldability, ease of insertion into a living body, or retention after insertion. For example, if a hard substance such as metal is used as a constituent material of the cannula, it is suitable for temporary puncture insertion,
Prolonged retention in the body requires the patient or animal to be shut off, causing extra pain.
Furthermore, when inserting a cannula made of a hard substance into the body, there is a problem that it is necessary to make a large incision by surgery, and that it is necessary to pay sufficient attention to suturing after insertion and postoperative management. .

On the other hand, when a soft substance such as silicone rubber is used as a constituent material of the cannula, the cutout for mounting the cannula can be inserted sufficiently even if it is small, and it expands and contracts to some extent in accordance with the movement of the body. Less pain to the animal. However, they have the disadvantage that they are easily detached when an external force is applied, and that the liquid is apt to leak.

[0006] As a cannula that solves such a drawback, a digestive tract cannula in which a cylindrical portion made of a soft material is provided with a collar portion on the outside and inside of the body has been proposed (for example,
JP-A-3-85177 and JP-A-4-300536.

[0007]

However, in order to analyze the tertiary function or digestive process of food or feed, a cannula to be attached to organs such as the rumen, liver, and pancreas of a ruminant animal is required. Since the conventional gastrointestinal cannula is configured to be mounted on a portion near the outer skin tissue in the body cavity, it cannot be mounted on the organ located deep in the body cavity.

In addition, since the above-mentioned conventional gastrointestinal cannula is opened at the inner brim portion inside the body, the purpose cannot be achieved even when the cannula is attached to the above-mentioned organ having a complicated structure. For example, in the case of the rumen of the ruminant, folds of different heights, large lobe, middle lobe, and small lobe, are formed on the inner wall, so even if the cannula is open at the inner collar, the large lobe covers the opening. As a result, the contents inside the third stomach cannot be effectively removed. In the liver, pancreas, etc.
Problems such as the inability to collect fluid inside the organ from the opening of the inner collar attached near the surface of the organ, because the conduit for secretion fluid such as bile and pancreatic fluid is open deep in the organ There is a point.

[0009] An object of the present invention is to solve the above-mentioned problems without damaging the tissue, causing no pain to the living body even when worn for a long time, and without detachment even when an external force is applied. An object of the present invention is to provide an organ cannula that can be easily inserted from a small fistula, can easily and efficiently extract secretion fluid and contents from a deep part of an organ, or inject a drug or the like, and can be easily manufactured.

[0010] Another object of the present invention is to provide an organ cannula that can be easily attached to organs located deep within a body cavity.

[0011]

The present invention is the following organ cannula. (1) A body made of a soft tubular body inserted into a fistula formed from the skin to the inner wall of the organ through the body tissue, and integrally formed on the outside of the body so as to be in contact with the skin The outer collar portion, an inner collar portion integrally formed inside the body of the body portion so as to be in contact with the inner wall of the organ, and projecting from the inner collar portion to a predetermined opening position inside the inner wall of the organ. A protruding tube portion extending integrally with the protruding tube portion, an inner plug removably mounted in the protruding tube portion, and a hook portion extending from the inner plug into the body portion, and having rigidity and flexibility. Organ cannula having a member. (2) The organ cannula according to the above (1), wherein the body is formed of a cylindrical body. (3) The organ cannula according to the above (1) or (2), wherein a mesh member for securing an organ is attached to the body.

In the present invention, the body, the outer collar, the inner collar, and the protruding tube are preferably integrally formed of a soft material. As the soft material, silicone resin, silicone rubber, and the like are preferable. The mesh member attached to the body may be fixed to the cylindrical body by bonding or the like, but is preferably embedded in a molded product. As the mesh member, a polyester mesh used as a prosthetic material for septal defect in a surgical operation or the like can be used.

The inner plug may be any one which can be detachably mounted in the protruding tube and can be hermetically sealed, but is preferably a soft one having a certain degree of rigidity and flexibility, such as silicone resin or silicone rubber. The holding member is preferably a long material having a certain degree of rigidity and flexibility, such as a stainless steel spring, and one end thereof is preferably embedded in the inner plug.

The length of the body is the length from the skin to the inner wall of the target organ, and the length of the protruding tube is the length from the inner wall of each organ to the target opening position. Although these vary depending on the individual, those having an average length can be used.

[0015]

The organ cannula of the present invention is attached by inserting a body, an inner brim and a protruding tube into a fistula formed by incising the skin and organs. At this time, the protruding tube portion and the inner collar portion are inserted into the organ in a folded state, the inner collar portion is expanded inside the organ, and the protruding tube portion is protruded to open at a target opening position.

If there is a net-like member, the net-like member is spread and wound around the organ in this state, and the ends are sewn and secured. In this state, the inner plug is mounted in the protruding tube. The installation of the inner stopper
Using an applicator or the like, the body is pushed from the outside of the body into the protruding tube part through the inside of the body part to be sealed.

In the mounted state, the inner collar is in close contact with the inner wall of the organ to prevent leakage of exudate and contents. Although the cannula is secured without the reticulation, the reticulation secures the entire body to the organ and prevents it from being removed from the body. The outer collar fits tightly against the skin and prevents the cannula from being pulled into the body. The inner stopper is sealed so that the exudate and contents do not leak through the cannula.

Removal of secretions, contents and the like from organs and injection of drugs and the like are performed by attaching and detaching an inner stopper. At this time, since the holding member has a certain degree of rigidity and flexibility, even if the body part is deformed due to internal pressure, it is held in a stretched state inside the body and easily operated from the outside of the body, Drawer to
Or you can push it.

[0019]

Embodiments of the present invention will be described below. FIG. 1 is a cross-sectional view showing a mounted state of an organ cannula of an embodiment;
FIG. 2 is a development view of the mesh member, and FIG. 3 is a front view of the applicator.

In FIG. 1, reference numeral 1 denotes a cannula main body having a long cylindrical body 2, a donut plate-shaped outer brim 3, a bowl-shaped inner brim 4, and a short cylindrical protruding tube 5 formed of silicone resin. , Etc., and are integrally formed. The body 2 has a length to be attached to a fistula 14 formed from the skin 11 through the body tissue 12 to the inner wall of the organ 13, and a circumferential rib 6 is formed at a peripheral portion.

The outer brim portion 3 is formed integrally with the outside of the body portion 2 and the inner brim portion 4 is formed integrally with the inside of the body. The protruding tube portion 5 integrally extends from the inner collar portion 4 into the organ 13 so that the body portion 2 extends. Organ 1 in FIG.
Reference numeral 3 denotes the case of the third stomach of a sheep, and since a fold 15 such as a large leaf, a middle lobe, or a small leaf is formed on the inner wall, the protruding tube portion 5 is opened at a predetermined opening position 16 inside the fold 15. .

A groove-like engaging recess 7 is formed on the inner wall near the inner flange 4 of the body 2, and a mesh member 8 such as polyester mesh having a certain degree of rigidity and flexibility is formed on the outer periphery thereof. The opening peripheral portion 9 is fixed by embedding. As shown in FIG. 2, the mesh member 8 has an opening 17 at the center, and an opening peripheral portion 9 located around the opening 17 is embedded in the body 2. The mesh member 8 is sized to be wound around the organ 13 and sewn at the end 18 with a sewing material 19.

Reference numeral 21 denotes an inner plug formed of a soft material such as silicone resin into a cylindrical shape with a bottom, and is attached to the inner flange side of the body 2 of the cannula main body 1 and to the protruding tube 5. At the tip (bottom) of the inner plug 21, a protruding tube 5
A fin 22 is formed to cover the tip of the rim, and a rib-shaped engaging convex portion 23 that engages with the engaging concave portion 7 is formed in an intermediate portion. A solid portion 24 is formed by filling resin between the fin 22 on the distal end side of the inner plug 21 and the engaging convex portion 23, and has a structure having a certain degree of rigidity and flexibility. It comes into close contact. Engagement protrusion 2 of inner plug 21
The outside of the body from 3 is a cylindrical portion 25.

Reference numeral 26 denotes a holding member, which is composed of a stainless steel coil spring having a certain degree of rigidity and flexibility, and one end 27 of which is embedded in the solid portion 24 through the cylindrical portion 25 of the inner plug 21. . A hook 29 is formed on the protruding end 28 of the holding member 26.

Reference numeral 31 denotes an applicator, which is made of a stainless steel wire, has a hook 32 formed at one end thereof for engaging with the hook 29 of the holding member 26, and a holder 33 for holding by hand at the other end. I have.

The above-mentioned cannula is inserted through a fistula 14 formed by incising the skin 11 and the organ 13 into the body 2, the inner collar 4 and the protruding tube 5 of the cannula main body 1, and the outer collar 3 is cut into the skin. 11 and attached. At this time, if there are other organs as the body tissue 12, they are attached so as to avoid them. Then, with the protruding tube portion 5 and the inner collar portion 4 folded into the body portion 2, insert the distal end portion of the body portion 2 into the organ 13, expand the inner collar portion 4 inside the organ 13, and The pipe portion 5 is made to protrude, and a predetermined opening position 16 is set.
To open.

As a result, the inner brim portion 4 is in a bowl shape, so that it fits the inner wall of the organ 13. In this state, the mesh member 8
Is spread and wound around the organ 13, the end 18 is sewn with a sewing material 19 and secured, and the inner plug 21 is attached to the inner flange 4 side of the body 2 and the protruding tube 5.

The inner plug 21 is attached by holding the inner plug 21 by hand and pushing the inner plug 21 into the body 2 from the side of the outer collar 3 to a certain extent. Then, the hook 32 of the applicator 31 is connected to the solid portion 2 of the inner plug 21.
4, or by pushing against the hooking portion 29 of the holding member 26. At this time, after the inner plug 21 is pushed into the protruding tube 5 to such an extent that it protrudes slightly, the hook of the applicator 31 is
9, the engaging projection 23 engages with the engaging recess 7, the fin 22 covers the distal end of the protruding tube 5, and the inner plug 21 and the holding member 26 correspond to the chain lines 21a, 26a in FIG. It is mounted in the position shown in and keeps hermetically sealed.

In this state, the wound is sutured, and after a lapse of time, the wound is closed, and a protective tissue 35 such as fat or connective tissue is deposited around the body 2 to form a complete fistula 14 and the attachment is completed. .

In the mounted state, the inner collar portion 4 is in close contact with the inner wall of the organ 13 to prevent leakage of exudate and contents, and the mesh member 8 secures the entire cannula to the organ 13 and detaches it from the body. To prevent The outer brim portion 3 is in close contact with the skin 11 to prevent the cannula main body 1 from being pulled into the body.

The inner plug 21 is sealed so that the exudate and the contents in the organ 13 do not leak through the body 2. At this time, the solid portion 24 of the inner plug 21 is tightly supported on the inner wall of the body portion 2 and the protruding tube portion 5 in the vicinity of the inner flange portion 4 where the organ 13 is to be mounted, thereby preventing liquid leakage due to these deformations.

Since the cannula main body 1 and the inner plug 21 are formed of a soft material, the skin 11, body tissue 1
2. Does not damage the organ 13 and does not cause any pain to the living body. The body 2 is bent or compressed and deformed due to the activity of the body tissue 12 or the organ 13. However, a holding member 26 having a certain degree of rigidity and flexibility is inserted into the body 2 in a core shape. Therefore, attachment / detachment of the inner stopper 21 is easily performed.

The inner plug 21 is removed by inserting the applicator 31 from the outer collar 3 into the body 2 and hooking the hook 32 on the hook 29 of the holding member 26 and pulling the hook 32 out of the body.
1 is drawn through the inside of the body 2.

In this state, secretions, contents, etc. in the organ 13 are taken out through the body 2 and the protruding tube 5, or a drug solution or the like is injected into the organ 13. In this case, the projecting tube portion 5
Since the tip of is opened at the opening position 16 suitable for these purposes, the above-mentioned removal and injection can be performed efficiently.

In the embodiment, a cannula body having an inner diameter of 14 mm, a length of the body portion 2 of 70 mm, and a length of the protruding tube portion 15 of 15 mm is integrally formed with a silicone resin KE1600 (trade name, manufactured by Shin-Etsu Chemical Co., Ltd.). A prosthetic material for septal defect (328 mesh) made of polyester mesh was embedded. On the other hand, the length of the solid part 24 is 18 mm,
An inner plug 21 having a length of 5 mm and a length of 17 mm was integrally formed of the same resin, and a holding member 26 made of a stainless steel spring having a length of 70 mm and an outer diameter of 8 mm was embedded in the solid portion 24.

The cannula main body 1 was attached to a fistula formed from the abdomen of the sheep to the third stomach. 30 wearing surgeries
In less than 3 minutes, the exudate from the surgical site stops within 3 days, there is no inflammation or leakage, the living body recovers to a normal state, and the inner plug 21 can be easily attached and detached without the cannula main body 1 falling off. Then, the contents could be taken out.

In the embodiment shown in FIG. 1, the organ 13 is the stomach of the sheep, and the protruding tube portion 5 protrudes from the fold 15 to the flow path of the digested matter inside. Can be taken out. When the organ 13 is a liver-easy organ, opening the protruding tube portion 5 near a conduit for secretion fluid such as bile-prone fluid allows for efficient extraction of these exudates.

In the above description, the ruminal stomach, liver, and pancreas of a ruminant animal are described as the organ 13, but other organs can be mounted. In this case, these organs need not necessarily be deep within the body cavity. Further, the cannula of the present invention can be applied not only to ruminants but also to other animals. Further, in the present invention, the cannula main body 1, the inner stopper 2
1. The structure, material, and the like of the applicator 31 and the like are not limited to those in the above-described embodiment, and can be changed.

[0039]

The organ cannula of the present invention has a body, an outer brim, an inner brim, and a protruding tube. An inner plug is attached to the protruding tube, and the inner plug can be taken in and out by the holding portion. Therefore, it does not harm the living body even if worn for a long time without damaging the tissue, it does not detach even if external force is applied, and the inner plug can be easily attached and detached even if the trunk is deformed, and exudate from the deep part of the organ Thus, an organ cannula can be obtained which can easily and efficiently take out the contents or take out the medicine or inject the medicine and can be easily manufactured.

[Brief description of the drawings]

FIG. 1 is a sectional view showing an attached state of an organ cannula.

FIG. 2 is a development view of a mesh member.

FIG. 3 is a front view of the applicator.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Cannula main body 2 Body part 3 Outer brim part 4 Inner brim part 5 Projection pipe part 6 Rib 7 Engaging concave part 8 Net-like member 9 Peripheral part of opening 11 Skin 12 Body tissue 13 Organ 14 Fistula 15 Fold 16 Opening position 17 Opening 18 End Part 19 Sewing material 21 Inner plug 22 Fin 23 Engagement convex part 24 Solid part 25 Cylindrical part 26 Holding member 27 One end part 28 Protruding end part 29 Hook part 31 Applicator 32 Hook 33 Holder

────────────────────────────────────────────────── ─── Continuation of the front page (56) References JP-A-4-300536 (JP, A) JP-A-3-85177 (JP, A) JP-A-57-20272 (JP, A) (58) Investigation Field (Int. Cl. ⁷ , DB name) A61M 25/00 420 A61M 37/00

Claims (3)

(57) [Claims] 1. From the skin to the inner wall of an organ through body tissues
A body portion made of a soft tubular body inserted into a fistula formed so as to reach, an outer brim portion integrally formed outside the body of the body portion so as to be in contact with the skin, and an inner wall of the organ. An inner collar formed integrally with the inside of the body so as to be in contact with the body, and a predetermined opening inside the inner wall of the organ from the inner collar
A projecting tube portion extending integrally so as to protrude to a position , an inner plug detachably mounted in the projecting tube portion, and a hook portion extending from the inner plug into the body portion to form a rigid portion, An organ cannula having a flexible retaining member. 2. A body according to claim 1, wherein said body comprises a cylindrical body.
The described organ cannula. 3. An organ cannula according to claim 1, wherein a mesh member for securing an organ is attached to the body.