JP3068265U - Continuous chemical injector - Google Patents

Abstract

(57) [Summary] [Problem] A continuous injection of a chemical solution that can easily perform operation preparation with a small force, is easy to handle, and can inject a chemical solution over a long period of time at a constant injection speed and volume. Provision of equipment. The liquid pump includes a liquid syringe, and a drive pump mounted on the liquid syringe, and slides a pressing arm of the drive pump toward an upper end to form a piston in the negative pressure chamber. Using the force that the piston returns by sliding in the axial direction to generate a negative pressure in the negative pressure chamber, the chemical liquid cylinder is pushed through the locking member engaged with the piston and the upper edge of the pushing member. The chemical liquid in the chemical liquid syringe is extruded from the chemical liquid injection port by the urging push member, and the chemical liquid continuous injector is provided.

Description

[Detailed description of the invention]

[0001]

[Technical field to which the invention belongs]

 The present invention relates to a continuous drug solution injector, in particular, which can easily be prepared for operation with a small force, is easy to handle, and injects a drug solution at a constant injection rate and volume over a long period of time. The present invention relates to a continuous drug solution injector.

[0002]

[Prior art]

 When injecting a therapeutic drug into a human or animal body, a drug solution may be continuously injected at a constant flow rate for a long time. For example, transfusions such as nutrient solutions, anticoagulants, anticancer drugs, analgesics, local anesthetics, and blood sugar regulators in the form of a solution over a long period of time in the form of a solution in the patient's body, such as veins, arteries, or subcutaneously. In some cases, it is necessary to inject at a constant flow rate from the epidural or the like.

[0003] In such a case, conventionally, an injector using an electric syringe pump, an injector (balloon infuser) for injecting by using the contraction force of a balloon having elasticity, and the elasticity of the spring have been improved. Injectors and the like that have been used have been used. However, an injector using an electric syringe pump is heavy, inconvenient to carry as the patient moves, and the structure is complicated and expensive. In addition, in the balloon infuser, the contraction force of the balloon is not constant, the discharge force of the drug solution is not constant, it is difficult to continuously inject the drug solution at a constant flow rate, and the drug solution remains in the balloon. Sometimes. . Furthermore, the conventional liquid injectors driven by these balloons, springs, and the like have difficulty in maintaining the accuracy and accuracy of the liquid injection speed and volume over a long period of time.

[0004] Therefore, a second cylinder whose internal pressure is made negative by the operation of a piston or the like is mounted on the first cylinder filled with the chemical solution, and the first cylinder is driven by the negative pressure in the second cylinder. There has been proposed a drug solution injector for extruding a drug solution from the inside (Japanese Utility Model Application Laid-Open No. 5-20751, Japanese Patent Application Laid-Open No. 5-176997, International Publication WO95 / 28977).

[0005]

[Problems to be solved by the invention]

 However, these conventional injectors using negative pressure require a large force to operate a piston or the like to generate negative pressure, and are not easy to handle. For example, since a piston is slidably fitted on a center shaft inserted in the center of the second cylinder, the piston is attached to the center shaft when a chemical solution is injected and a negative pressure is formed in the second cylinder at the same time. The seal resistance is high due to the O-ring or other air-tightness holding member disposed between the center shaft and the piston in order to fit airtightly, or the piston is pushed up to prevent air leakage etc. Requires a great deal of power. In addition, since it has a unique structure such as a center shaft provided in the second cylinder, care must be taken in handling and the manufacturing cost is high. Furthermore, it was difficult to maintain the negative pressure, which is the driving force source for injection, constant over a long period of time, and there was a problem in the accuracy of the injection speed and amount of the drug solution.

[0006] Therefore, an object of the present invention is to allow a chemical solution to be introduced into a chemical solution syringe with a smaller force than a conventional solution injector using a negative pressure, and to reduce a small force by a small drive pump unit. And preparation for operation is easy, and it is easy to inject arteries requiring a pressure of 300 mmHg or more. The simple structure allows easy handling, the liquid syringe section and the drive pump section can be separated, which is advantageous in terms of cost, and there is no excessive air leakage or excessive sliding resistance. Another object of the present invention is to provide a continuous drug solution injector that can perform injection while keeping the injection speed and amount of the drug solution constant, and is excellent in durability.

[0007]

[Means for Solving the Problems]

 In order to solve the above-mentioned problem, the present invention has a drug solution syringe portion and a drive pump portion mounted on the drug solution syringe portion, and the drug solution syringe portion has a drug solution inlet at one end and a drug solution inlet at the other end. It has an opening connected to the bottom end of the drive pump section, has a liquid filling chamber communicating with the liquid inlet, and has a peripheral edge slidably in contact with the inner peripheral wall of the liquid filling chamber. An extruding member slidably and reciprocally slidable in the axial direction of the liquid syringe portion in a gas-tight and liquid-tight manner is provided, and the drive pump portion has a bottom end portion in contact with an upper edge end of the extruding member, and a bottom end portion. A liquid medicine cylinder having at least two pressing arms connected and fitted along the inner peripheral wall of the liquid medicine filling chamber; a negative pressure chamber fitted inside the liquid medicine cylinder and having a negative pressure chamber therein; A negative pressure cylinder fitted with a piston that generates a negative pressure by sliding hermetically in the chamber in the axial direction. By sliding the pressing arm of the drive pump toward the upper end, the piston in the negative pressure chamber is slid in the axial direction and pushed up to generate a negative pressure in the negative pressure chamber, Utilizing the force of the piston returning by the negative pressure, the liquid medicine cylinder is urged toward the upper edge end of the push-out member via the locking member engaged with the piston, and the pushed-out member is urged by the urged push-out member. Another object of the present invention is to provide a continuous drug injector in which a drug solution in a drug syringe is extruded from a drug solution inlet.

[0008] According to another aspect of the present invention, there is provided a continuous drug injector, wherein the drug syringe unit and the drive pump unit are configured to be separable.

Further, according to another aspect of the present invention, the liquid medicine syringe section is constituted by a plurality of sub-syringe sections, and the pressurization corresponding to each of the pushing members fitted into the plurality of sub-syringe sections. There is provided a continuous drug solution injector having an arm portion and a bottom end portion.

Hereinafter, the continuous drug injector according to the present invention (hereinafter referred to as “the injector of the present invention”) will be described in detail. The injector of the present invention has a liquid syringe and a drive pump mounted on the liquid syringe. The liquid syringe and the drive pump may be fitted together to suck the liquid into the liquid syringe, or the drive pump may be separated from the liquid syringe, and after preparation for operation, the liquid syringe filled with the liquid. It may be configured to be attached to a part.

[0011] In the injector of the present invention, the drug solution syringe section has a drug solution chamber for sucking a drug solution or filling with a drug solution. Provided. The liquid medicine inlet may form an opening to which a liquid medicine tube or the like from which the liquid medicine flows out is connected, or is closed by a closing member such as rubber pierced from the outside by a liquid outflow member such as an injection needle. You may. In addition, the chemical solution inlet and the chemical solution outlet are located at different points in the chemical solution syringe, and are connected to dedicated chemical tubes for injecting the chemical solution into and out of the chemical solution, respectively. May be. At the other end of the liquid syringe, an opening is provided to which the bottom end of the drive pump is connected. Further, inside the chemical liquid filling chamber, an extruded member having a peripheral edge which is formed so as to correspond to a cross section in a direction perpendicular to the axial direction of the chemical liquid filling chamber and is in sliding contact with the inner peripheral wall of the chemical liquid filling chamber is provided therein. I have. The pushing member is reciprocally slidably and reciprocally slidably and airtightly and liquid-tightly by the peripheral edge in the axial direction of the chemical liquid filling chamber. The extruded member and the peripheral edge are made of a material having flexibility and elasticity such as rubber so as to be in air-tight and liquid-tight sliding contact with the inner peripheral surface or the inner bottom surface of the liquid syringe.

[0012] In the injector of the present invention, the drug solution syringe section may be composed of a plurality of sub-syringe sections. This injector having a plurality of sub-syringes can be made compact, avoiding the increase in the size of the instrument, especially the increase in thickness, and is equipped with an injector to inject the drug solution. It is effective in that it is convenient to move and carry the user. For example, there is a form having two sub-syringes and combining two sub-syringes having a circular cross-section to form an elliptical cross-section as a whole. The liquid syringe having an elliptical cross section is effective in that it does not hinder the user from carrying or putting on the body. As a specific example of the injector having the drug solution syringe section including the plurality of sub-syringe sections, an injector having two sub-syringe sections having a structure shown in FIG. 13 described later is given.

[0013] In the case where the liquid syringe is formed by arranging a plurality of sub-syringes in parallel, the thickness in one direction of the injector can be reduced. Further, the drive pump section may be arranged in parallel according to the chemical syringe section.

[0014] In the injector of the present invention, the drive pump section has a drug solution cylinder section and a negative pressure cylinder fitted in the drug solution cylinder. The chemical liquid cylinder section has a bottom end that contacts the upper edge of the pushing member, a pressing arm connected to the bottom end, and an upper end disposed above the pressing arm. . A stopper for the piston of the negative pressure cylinder may be provided at the upper end, and the stopper may be inserted into this stopper and locked.

The pressing arm portion is fitted and inserted along the inner peripheral wall of the drug solution filling chamber of the drug solution syringe portion, and at least two pressing arms are formed. Each of the pressing arms has a substantially arcuate cross section along the inner peripheral surface of the chemical liquid filling chamber, and a notch between the pressing arms opens from the bottom end to the upper end. Alternatively, the pressing arm may be closed near the upper end, and the pressing arm may converge to form an annular cross section.

A negative pressure cylinder having a negative pressure chamber therein is fitted in the chemical liquid cylinder portion. In the negative pressure chamber, a piston that generates air in the negative pressure chamber by sliding axially in the negative pressure chamber in an airtight manner is fitted. The piston has an airtight holding member, such as a rubber plunger or an O-ring, provided on the outer peripheral surface and made of an elastic material such as rubber. The negative pressure chamber is kept airtight. Further, a stopper that engages with the locking member inserted from the upper end of the chemical liquid cylinder may be provided at the upper part.

In the injector of the present invention, in the case of a separate type injector, the axial driving distance of the pressing arm driven by the negative pressure generated in the negative pressure chamber of the negative pressure cylinder is equal to the driving distance. The length of the negative pressure chamber in the axial direction, the length of the pressing arm, and the like are configured to be larger than the length of the pump section in the axial direction of the chemical liquid cylinder section. For example, in the case of an injector having a 60 ml capacity liquid medicine syringe part, the axial driving distance of the pressing arm part by the length corresponding to 10 ml in terms of the amount of liquid medicine in the liquid medicine syringe part is equal to the liquid medicine cylinder. It is formed to be extra large than the length of the part. Further, in the case of an integrated injector, a preliminary negative pressure is formed in the negative pressure cylinder before the liquid chemical is introduced into the liquid syringe. As a result, during the operation of extruding and injecting the liquid medicine filled in the liquid medicine filling chamber of the liquid medicine syringe section from the liquid medicine injection port, the liquid medicine is injected at a constant injection pressure and speed. At the end of injection, the pushing member is pressed with a constant driving force by the bottom end of the pressing arm, so that no chemical liquid remains in the chemical filling chamber, and no expensive chemical liquid is wasted until the last drop. It is extruded with a constant force and can be used effectively.

In the injector of the present invention, when the liquid syringe and the drive pump are of a separable type, the drive pump is operated to push up the piston in the liquid cylinder in the axial direction. When a negative pressure is formed in the negative pressure chamber and the stopper of the piston engages with the locking member inserted from the upper end of the chemical liquid cylinder, the axial position of the bottom end of the chemical liquid cylinder portion is the position of the chemical liquid filling chamber. Is formed so that a gap of about 1 to 2 mm is usually formed between the pushing member and the axial position of the upper end of the pushing member when the pushing member is at the highest position. By forming this gap, the initial movement of the chemical liquid cylinder part of the drive pump unit at the time of chemical liquid injection can be made smooth, which is effective.

The liquid syringe and the drive pump that constitute the injector of the present invention, and the members that constitute each part can be made of various materials used for this type of instrument, and are not particularly limited. The liquid syringe is formed of a transparent or translucent material so that the amount of liquid stored in the liquid syringe can be visually recognized from the outside. When handling a chemical solution that changes due to light or the like, it may be colored translucent or a color that cuts off the corresponding light component. In the case of a transparent or translucent material, a scale may be provided on the outside as a measure of the amount of the chemical solution.

The injection of the chemical solution by the injector according to the present invention is performed by first sliding the pressing arm of the drive pump toward the upper end, thereby sliding the piston in the negative pressure chamber in the axial direction to push up the negative pressure. A negative pressure is generated in the pressurized chamber, and the chemical liquid cylinder is urged toward the upper edge end of the push-out member through a locking member engaged with the piston by using a force of returning the piston by the negative pressure, This can be performed by extruding the drug solution in the drug solution syringe from the drug solution inlet with the urged pushing member.

Hereinafter, the present invention will be described based on an embodiment shown in FIGS. 1 to 11 of the injector of the present invention. 1 to 6 show an example of a separate type injector as an embodiment of the injector of the present invention. The injector shown in FIGS. 1 to 4 has a drug solution syringe section 2 and a drive pump section 3. As shown in FIG. 1, the drug solution syringe section 2 has a drug solution filling chamber 4 into which a drug solution is filled, and a drug solution inlet 5 through which the drug solution passes during injection or suction of the drug solution is provided at one end. A chemical tube or the like is attached to the tip of the chemical solution inlet 5 at the time of chemical solution injection. The other end of the chemical syringe 2 is provided with an opening 6 to which the bottom end of the drive pump 3 is connected. The inside of the chemical filling chamber 4 has a cross-sectional shape corresponding to a cross section perpendicular to the axial direction of the chemical filling chamber 4, and has a peripheral edge 8 slidably in contact with the inner peripheral wall 7 of the chemical filling chamber 4. The extruding member 9 provided with is provided. The push-out member 9 is reciprocally slidably and reciprocally slidably and airtightly and liquid-tightly by the peripheral edge 8 in the axial direction of the chemical liquid filling chamber 4. A press receiving member 10 is fitted into the pushing member 9 on the opening 6 side. The liquid syringe 2 is formed of a transparent or translucent material so that the liquid filled therein can be checked. The liquid syringe filled in the liquid filling chamber 4 is formed on the outer peripheral surface of the liquid syringe 2. A scale for confirming the amount may be engraved.

As shown in FIG. 1, the drive pump section 3 has a plunger cylinder 12 and a vacuum pump cylinder 13 fitted in the plunger cylinder 12. The plunger cylinder 12 has a bottom end portion 15 which is in contact with the upper edge end 14 of the pushing member 9 as shown in a partially cutaway plan view in FIG. 5 (A) and a bottom view in FIG. 5 (B). It has a substantially cylindrical base 31 having the pressing arm 16 and two locking stoppers 23a and 23b formed on the outer periphery of the base 31. The locking stopper 23a or 23b is formed in a tongue shape by engraving a substantially U-shaped groove 32 in a part of the outer periphery of the base 31, and has the engaging claw 22 on the outer periphery. The locking stoppers 23a and 23b form an elastic member by the groove 32. When a force is applied from above the locking claw 22, the locking stoppers 23a and 23b are bent inward and disengaged from the member abutting the tip 33. It operates at

As shown in FIG. 6A and FIG. 6B, the vacuum pump cylinder 13 has a cylindrical peripheral groove through which the pressing arm 16 of the plunger cylinder 12 is inserted. A negative pressure cylinder 17 which is slidably inserted into the liquid filling chamber 4 along the inner peripheral wall of the liquid filling chamber 4 concentrically with the peripheral groove 18 interposed therebetween; An outer cylinder portion 24 is provided outside the pressing arm portion 16 of the cylinder 12 and annularly externally provided. At the end of the negative pressure cylinder 17, there is formed a tip sliding portion 19 slidably in contact with an inner wall of a peripheral groove 18 provided in the plunger cylinder 12.

Further, as shown in FIG. 1, a piston member 20 that is in airtight sliding contact with the inner peripheral wall of the negative pressure cylinder 17 is fitted in the negative pressure cylinder 17. The piston member 20 is connected to a piston holding member 27 attached to the inner bottom end 34 of the base 31 of the plunger cylinder 12.

In the injector shown in FIG. 1, first, as shown in FIG. 1, an extruding member 9 is inserted into the chemical liquid filling chamber 4 of the chemical liquid syringe part 2 from the opening 6 side, and the chemical liquid inlet 5 is formed. The pressing receiving member 10 is further fitted to the pushing member 9. In the drive pump unit 3, a piston member 20 is fitted to a piston holding member 27 attached to the inner bottom end 34 of the base 31 of the plunger cylinder 12, and the piston member 20 is attached to the vacuum pump cylinder 13. The two pressure arms 16 are inserted into the peripheral groove 18 of the vacuum pump cylinder 13 to assemble the drive pump 3. At this time, the inner surface of the distal end sliding portion 19 of the negative pressure cylinder 17 is in sliding contact with the inner surface of the peripheral groove portion 18 of the plunger cylinder 12.

Next, as shown in FIG. 2, the liquid medicine is injected from the liquid inlet 5 of the liquid syringe section 2 and the extruded member 9 is pushed up in the axial direction, so that the liquid filling chamber 4 is filled with the liquid medicine. In the drive pump unit 3, for example, after the drive pump unit 3 is set up with the plunger tube 12 up, the outer tube unit 24 of the vacuum pump tube 13 is connected to the bottom end of the pressing arm 16. 15, the negative pressure cylinder 17 is pushed down in the axial direction of the drive pump section 3. Thus, a negative pressure chamber 26 is formed in the negative pressure cylinder 17. At this time, the locking claw 22 at the tip of the outer arm of the plunger cylinder 12 is brought into contact with the end 25 of the pressing arm 16 so that the piston member 20 is locked and fixed. The inside of the negative pressure cylinder 17 slides, and a negative pressure chamber is formed in the negative pressure cylinder 17.

In the injector 1, the drive pump 3 can be operated with a small force enough to push down the outer cylinder 24, and a necessary and sufficient negative pressure can be generated in the negative pressure chamber 26. Therefore, it is effective.

Next, as shown in FIG. 3, the pressure arm 16 side of the drive pump unit 3 is connected to the opening 6 of the drug solution syringe 2 in which the drug solution is filled in the drug solution filling chamber 4, and Complete operation preparation. After the preparation of the injection of the drug solution is completed by connecting a drug solution tube or the like to the drug solution inlet 5 of the injector, two locking stoppers 23a and 23b formed on the outer periphery of the base 31 of the plunger cylinder 12 are connected. When a force is applied from above the locking claw 22, it bends inward and disengages from the outer cylindrical portion 24 which abuts on the tip 33, and the tips of the two locking stoppers 23a and 23b are connected to the negative pressure cylinder. As shown in FIG. 4, the piston member 20 is inserted into the negative pressure chamber 26 so that the negative pressure generated in the negative pressure chamber 26 is released. Of the plunger cylinder 12 connected to the piston member 20 is urged toward the upper edge end of the pushing member 9 by the force returning toward the bottom end of the negative pressure cylinder 17. The extruded member 9 allows the medicine in the medicinal solution syringe 2 to be removed. Extrusion, injection of the drug solution is performed from the chemical inlet 5.

In the injector shown in FIGS. 1 to 6, the chemical syringe unit 2 and the drive pump unit 3 are of a separated type constituted separately, so that there are few disposable members, and other Since parts can be used repeatedly, it is effective in reducing pollution caused by waste. Further, in the case of the separation type, as shown in FIGS. 7A and 7B, a chemical liquid cartridge 41 which can be filled with a chemical liquid in advance and sealed can be used. As shown in FIG. 7 (A), the drug solution cartridge 41 is filled with a drug solution in advance in the drug solution filling chamber 4 of the drug solution syringe unit 2 in the injector shown in FIGS. A removable lid member 43 is screwed into the provided screw portion 42. The chemical liquid inlet 5 is closed by an elastic closing member 44 made of rubber or the like, and an extruding member 9 and a pressure receiving member 10 fitted into the extruding member 9 are loaded in the chemical liquid filling chamber 4. When injecting a drug solution using the drug solution cartridge 41, after removing the lid member 43 from the opening 6 of the drug solution syringe section 2, similar to the drug solution syringe section in the injector shown in FIGS. A drive pump unit having a negative pressure chamber can be attached to inject a chemical solution. When the chemical liquid cartridge shown in FIGS. 7 (A) and 7 (B) is used, it can be used in a form in which the chemical liquid is filled in advance and sealed, thereby saving labor and safety in filling the chemical liquid. There are advantages that can be.

8 to 13 show another embodiment of the injector 51 of the present invention. FIGS. 8A and 8B are diagrams for explaining the overall configuration and operating mechanism of the injector 51. FIG. The injector 51 has a liquid syringe 52 and a drive pump 53. The chemical syringe 52 has a chemical syringe 55 having a chemical filling chamber 54 into which the chemical shown in FIG. 9B is filled, and one end of the chemical syringe 55 is used to inject the chemical into the chemical filling chamber 54. A chemical solution inlet 56 through which a chemical solution passes during suction or the like is provided. An elastic closing member 57 shown in FIG. 9A is fitted into the chemical liquid inlet 56. An injection needle or the like connected with a drug solution tube or the like is inserted into the elastic closing member 57 from the outside, and the drug solution flows out by the operation of the drive pump unit 53.

The other end of the chemical syringe 55 is provided with an opening 58 to which the bottom end of the drive pump unit 53 is connected. Further, inside the chemical liquid filling chamber 54, a peripheral edge 60 having a cross-sectional shape corresponding to a cross section perpendicular to the axial direction of the chemical liquid filling chamber 54 and slidingly contacting the inner peripheral wall 59 of the chemical liquid filling chamber 54 is provided. A push member 61 shown in FIG. 9C is provided. The pushing member 61 is reciprocally slidably and reciprocally slidably and airtightly and liquid-tightly in the axial direction of the chemical liquid filling chamber 54 by the peripheral edge 60. A pressure receiving member 62 shown in FIG. 9D is fitted into the pushing member 61. The convex portion 64 protruding from the conical mountain portion 63 of the pressure receiving member 62 is fitted into a concave portion 65 provided inside the mountain portion of the pushing member 61. The liquid syringe 55 is formed of a transparent or translucent material so that the liquid filled in the liquid syringe can be checked, and the amount of the liquid filled in the liquid filling chamber 54 is formed on the outer peripheral surface of the liquid syringe 55. There is a graduation on the scale to confirm.

The drive pump unit 53 is composed of the members shown in FIGS. The drive pump unit 53 includes a chemical liquid cylinder 66 whose bottom view is shown in FIG. 10A, its cross-sectional view is shown in FIG. 10B, and its top view is shown in FIG. 10C, the bottom view is shown in FIG. 12) includes a negative pressure cylinder 67 whose cross section is shown and a negative pressure cylinder member 68 whose components are shown in FIGS. 12 (A) to 12 (E).

As shown in FIGS. 10A to 10C, the chemical liquid cylinder 66 contacts a receiving portion 70 provided on an upper edge peripheral portion 69 of the pressing receiving member 62 fitted to the pushing member 61. The outer arm portions 71a, 71b, 71c, and 71d are in contact with each other and have an approximately arc-shaped cross section, and the upper lid portion 72 has an opening at the center at the upper end of the outer arm portions 71a, 71b, 71c, and 71d. The outer arm portions 71 a, 71 b, 71 c and 71 d pass through an arc-shaped insertion hole 75 formed in the lower part of the chemical liquid cylinder 66 along the inner peripheral wall of the chemical liquid filling chamber 54, and are formed inside the chemical liquid filling chamber 54. And the ends 73a, 73b, 73c and 73d come into contact with the receiving portion 70.

Further, the negative pressure cylinder 67 has a negative pressure chamber 74 inside as shown in FIG. 11B, and as shown in FIG. 11A, the outer peripheral arm portions 71a, 71b, 71c and An insertion port 75 through which 71 d penetrates is formed, and a piston member 76 shown in FIG. 12A fitted to the bottom end of the negative pressure cylinder member 68 shown in FIG. Negative pressure is generated by sliding airtightly in the axial direction. At the top of the piston member 76, a concave portion 78 into which a convex portion 77 projecting from the bottom end of the negative pressure cylinder member 68 is fitted is provided. The upper end of the negative pressure cylinder member 68 is screwed with a tightening member 79 shown in FIG. 12C, a fixing member 80 shown in FIG. 12D, and a screwing member 81 shown in FIG. The pressure cylinder member 68 is fastened and fixed to the upper lid 72 of the chemical liquid cylinder 66.

The piston member 76 has a function of keeping the inside of the negative pressure chamber 74 airtight by the side edge portion 82 being in close contact with the inner wall of the negative pressure chamber 74. This piston member 76 can be made of an elastic material such as rubber.

In the injector 51 shown in FIGS. 8 to 12, first, as shown in FIG. 13A, the extruding member 61 and the press receiving member 622 are put into the liquid filling chamber 54 of the liquid syringe 52, It is placed on the inner bottom. In the drive pump section 53, the negative pressure cylinder member 68 with the piston member 76 mounted at the tip is inserted into the negative pressure chamber 74, and the bottom port 83 of the negative pressure cylinder 67 is closed with an inner plug.

Next, as shown in FIG. 13B, the liquid syringe 52 is attached to the opening 57 of the liquid syringe 52, and the liquid syringe 52 and the drive pump 53 are connected. Thereafter, as shown in FIG. 13 (C), the outer peripheral arms 71a, 71b, 71c and 71d of the chemical liquid cylinder 66 are inserted through the circular arc-shaped insertion opening 75 into the chemical liquid filling chamber 54, and are pressed. Each end abuts on a receiving portion 70 provided on the upper edge peripheral portion 69 of the member 62. Further, a fastening member 79, a fixing member 80, and a screw fitting member 81 are screwed from the upper end side of the chemical liquid cylinder 66, and the negative pressure cylinder member 68 is attached to the chemical liquid cylinder 66 as shown in FIG. It is fastened and fixed to the upper lid 72. This creates a preliminary vacuum in the negative pressure cylinder.

From the assembled state shown in FIG. 8A, the injector 51 assembled as described above is moved from the liquid inlet 55 to the liquid filling chamber 54 from the liquid filling device inserted into the liquid inlet 55. A chemical solution is introduced into the inside. The extruding member 61 of the chemical liquid cylinder 66 is pressed in the axial direction of the chemical liquid syringe part 52 by the injection pressure of the chemical when introducing the chemical. When the pushing member 61 is pressed, the outer peripheral arm portions 71a, 71b, 71c and 71d are pushed up in the axial direction, and the piston member 76 disposed inside the outer peripheral arm portions 71a, 71b, 71c and 71d becomes negative pressure. A negative pressure is generated by sliding the inside of the chamber 74 in an airtight manner in the axial direction. At this time, by closing the chemical filling device inserted into the chemical inlet 55 or the chemical tube connected thereto, the negative pressure in the negative pressure chamber is maintained until the injection of the chemical starts. As shown in FIG. 8 (B), preparation for the injection operation of the chemical solution is completed.

Next, by opening a drug solution tube or the like communicating with the drug solution injection port 55, the pushing member 61 uses the force of the piston member 76 to return due to the negative pressure in the negative pressure chamber 74, so that the extruded member 61 is turned into the drug solution. The liquid medicine in the liquid medicine filling chamber 54 is pushed out from the liquid medicine inlet 55 by being urged to the inner bottom of the syringe part 52, and the liquid medicine is injected.

The injectors shown in FIGS. 8 to 13 can be made compact as a whole, and have the advantage that the operation of filling and injecting the drug solution is simplified.

Further, FIGS. 14A and 14B show a liquid injector 91 for explaining the structure and operation of the liquid injector 91. The liquid injector 91 includes two sub-syringes 92a and 92b, and two sub-syringes 92a and 92b. It has a triple-type liquid syringe 94 having a pump cylinder 93 disposed therebetween. Further, a triple-type plan in which extruding cylinders 95a and 95b fitted into the two sub-syringes 92a and 92b of the chemical syringe part 94 and a negative pressure cylinder 96 fitted into the pump cylinder 93 are connected in parallel. And a jar 97. The two sub-syringes 92a and 92b are connected to each other via communication paths 100a and 100b that branch off from a liquid inlet 99 in which a check valve 98 is provided.

Further, in the triple-type plunger 97, extruding members 101a and 101b are respectively attached to the distal ends of the extruding cylinders 95a and 95b so that the sub-syringes 92a and 92b slide in a liquid-tight manner. It is configured. A piston member 102 is attached to the tip of the negative pressure cylinder 96 so as to slide in the pump cylinder 93 in an airtight manner. The pushing members 101a and 101b and the piston member 102 may be the same as the pushing member or the piston member in the injector shown in FIGS.

In the injector shown in FIG. 14, when the triple plunger 97 is attached to the chemical syringe 94 as shown in FIG. 14 (A), the extruding cylinder is inserted into the sub-syringes 92 a and 92 b. 95a and 95b are inserted, and a negative pressure cylinder 96 is inserted into the pump cylinder 93. Next, the medicinal solution is injected and filled into the sub-syringes 92a and 92b from the medicinal solution inlet 99 through the check valve 98 and the communication paths 100a and 100b, and the pushing members 101a and 101b are urged to push the pushing cylinder 95. a and 95b are pressed and retracted. At this time, the negative pressure cylinder 96 connected to the extrusion cylinders 95a and 95b also retreats together with the piston member 102, and a negative pressure chamber 103 is formed in the pump cylinder 93. When the injection of the chemical solution is stopped, the negative pressure chamber is maintained, and the operation preparation of the injector is completed. Next, when a drug solution tube or the like is connected to the drug solution inlet 99 of the drug solution injector 91 and the check valve is opened, the negative pressure in the negative pressure chamber 103 causes the negative pressure cylinder 96 to return, and the pushing cylinder 95a And 95b are urged toward the chemical solution outlets 104a and 104b and slid, and the extruding member extrudes the chemical solution and discharges the chemical solution. The chemical solution passes through the communication paths 100a and 100b, and the chemical solution inlet port. Poured from 99.

The injector shown in FIG. 14 can be made into a compact shape while avoiding an increase in the size of the device, particularly, an increase in thickness, and is equipped with an injector for injecting a drug solution. It is effective in that it is convenient to move and carry the user.

[0045]

[Effect of the invention]

 The continuous drug injector according to the present invention is capable of introducing a drug solution into a drug syringe with a smaller force than a conventional drug injector using negative pressure. It is ready for operation and can be easily injected into arteries requiring a pressure of 300 mmHg or more. In addition, since the structure is simple, it is easy to handle, the syringe section and the drive pump section can be separated, which is advantageous in terms of cost, and further, air leakage and sliding resistance are too large. In addition, it is possible to perform the injection while keeping the injection speed and volume of the chemical solution constant, and it is also excellent in durability. In addition, when the liquid syringe and the drive pump are separated, only the liquid syringe is disposable, and the drive pump can be reused many times, which is cost-effective and It is effective in reducing pollution by goods.

[Brief description of the drawings]

FIG. 1 is a schematic cross-sectional view showing an example of a continuous drug solution injector according to the present invention.

FIG. 2 is a schematic cross-sectional view illustrating the preparation for operation of the continuous drug injector of the present invention shown in FIG. 1;

FIG. 3 is a schematic cross-sectional view illustrating an assembled state of the continuous drug injector of the present invention shown in FIG. 1;

FIG. 4 is a schematic cross-sectional view illustrating an operation of dispensing a drug solution by the continuous drug solution injector of the present invention shown in FIG. 1;

FIGS. 5A and 5B illustrate the structure of the plunger cylinder in the continuous liquid injector of the present invention shown in FIG. 1, wherein FIG. 5A is a partially cutaway plan view and FIG.

FIGS. 6A and 6B illustrate the structure of the vacuum pump cylinder in the continuous drug solution injector according to the present invention, wherein FIG. 6A is a cross-sectional view and FIG.

7A and 7B illustrate a drug solution cartridge used in a drug solution syringe part of the drug solution continuous infusion device of the present invention shown in FIG.
1 is a schematic cross-sectional view showing the configuration, and FIG. 1B is a schematic cross-sectional view showing an assembled state.

FIGS. 8A and 8B are schematic cross-sectional views illustrating a configuration and an operation mechanism of a continuous drug solution injector according to another embodiment of the present invention.

FIG. 9 is a schematic cross-sectional view illustrating the structure of a liquid syringe part of the continuous liquid injector of the present invention shown in FIG. 8;

FIG. 10 illustrates the structure of the pressing arm of the drive pump of the continuous drug injector of the present invention shown in FIG. 8, (A) is a bottom view,
(B) is a cross-sectional view, and (C) is a top view.

FIGS. 11A and 11B illustrate the structure of the liquid medicine cylinder of the drive pump unit of the continuous liquid medicine injector of the present invention shown in FIG. 8, wherein FIG. 11A is a bottom view and FIG.

FIGS. 12A and 12B illustrate the components of the negative pressure cylinder of the drive pump unit of the continuous drug injector of the present invention shown in FIG. 8, wherein FIG. 12A is a piston member, FIG. A fastening member, (D) is a fixing member, and (E) is a screw fitting member.

13 (A) to 13 (D) are views for explaining the assembling of the continuous drug injector of the present invention shown in FIG. 8 in order.

14A and 14B are schematic cross-sectional views illustrating a configuration and an operating mechanism of a continuous drug injector according to another embodiment of the invented continuous drug injector.

[Explanation of symbols]

 2 Chemical liquid syringe part 3 Drive pump part 4 Chemical liquid filling chamber 5 Chemical liquid inlet 6 Opening 7 Inner peripheral wall 8 Peripheral edge 9 Push member 10 Press receiving member 12 Plunger cylinder 13 Vacuum pump cylinder 14 Upper edge 15 Bottom end 16 Press Arm part 17 Negative pressure cylinder 18 Peripheral groove part 19 Tip sliding part 20 Piston member 22 Locking claw 23a, 23b Locking stopper 24 Outer cylinder part 25 End part 26 Negative pressure chamber 27 Piston holding member 31 Base 32 Groove 33 Tip 34 Inside Bottom end 41 Chemical liquid cartridge 42 Screw part 43 Cover member 44 Elastic closing member 51 Injector 52 Chemical liquid syringe part 53 Drive pump part 54 Chemical liquid filling chamber 55 Chemical liquid syringe part 56 Chemical liquid inlet 57 Elastic closing member 58 Opening 59 Inner peripheral wall 60 Peripheral edge End 61 Extrusion member 62 Press receiving member 63 Mountain part 64 Convex part 65 Recess 66 Chemical liquid syringe 67 Negative pressure cylinder 68 Negative pressure cylinder member 69 Upper edge peripheral part 70 Receiving part 71a, 71b, 71c, 71d Outer arm part 72 Upper lid part 73a, 73b, 73c, 73d End part 74 Negative pressure chamber 75 Insertion port 76 Piston member 77 Convex portion 78 Concave portion 79 Fastening member 80 Fixing member 81 Screw member 82 Side edge 83 Bottom opening 91 Chemical liquid injector 92a, 92b Sub-syringe part 93 Pump cylinder 94 Triple type chemical liquid syringe part 95a, 95b Push cylinder 96 Negative pressure Cylinder 97 Triple plunger 98 Check valve 99 Chemical inlet 100a, 100b Communication path 101a, 101b Push member 102 Piston member 103 Negative pressure chamber 104a, 104b Chemical outlet

Claims (3)

[Utility model registration claims] 1. A liquid syringe having a liquid syringe and a drive pump mounted on the liquid syringe, wherein the liquid syringe has a liquid inlet at one end and a bottom end of the drive pump at the other end. A liquid filling chamber communicating with the liquid inlet, and having a peripheral edge slidably in contact with an inner peripheral wall of the liquid filling chamber, the liquid peripheral portion being hermetically and liquid-tight by the peripheral end. An extruding member slidably reciprocally slidable in the axial direction of the extruding member is provided. A liquid medicine cylinder having at least two pressing arms inserted along the liquid medicine cylinder, a negative pressure chamber fitted inside the liquid medicine cylinder, and sliding in the negative pressure chamber airtightly in the axial direction. A negative pressure cylinder fitted with a piston for generating a negative pressure; By sliding the pressing arm toward the upper end, the piston in the negative pressure chamber is slid in the axial direction and pushed up to generate a negative pressure in the negative pressure chamber, and the negative pressure is used to return the piston. Then, the liquid medicine cylinder is urged toward the upper edge end of the push-out member via the locking member engaged with the piston, and the liquid medicine in the liquid medicine syringe is pushed out from the liquid inlet through the urged push-out member. A continuous drug solution injector characterized in that: 2. The continuous chemical injector according to claim 1, wherein the liquid syringe and the drive pump are configured to be separable. 3. The liquid syringe according to claim 1, wherein the liquid syringe comprises a plurality of sub-syringes, and has a pressing arm and a bottom end corresponding to each of the extruding members fitted into the plurality of sub-syringes. The continuous drug solution injector according to claim 1 or 2, wherein: