JP3055890B2 - Valves used for human body aerosol products - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a human-body Eyazoru products
It relates to the valve used . More particularly, the present invention relates to a valve for use in an aerosol product for a human body which is excellent in safety, particularly, for example, an aerosol product for a human body which can be suitably used as, for example, an aerosol antiperspirant having an excellent usability.

[0002]

2. Description of the Related Art In recent years, the amount of use of an aerosol product for a human body, particularly an aerosol antiperspirant, has been increasing. Antiperspirants include roll-on type and stick type in addition to the eazole type. However, since all of them are inferior in use feeling as compared with the aerosol type, the aerosol type is becoming mainstream. Further, among the eazole type, there are a type in which powder is compounded and a type in which powder obtained by dissolving the main agent in a solvent such as alcohol is not mixed. The type of an aerosol antiperspirant containing a powder has the advantage that the powder can be attached to the skin, so that the stickiness of the skin can be reduced.

[0003] However, the currently available commercially available type of eyazole antiperspirant containing a powder has the following disadvantages.

(1) The mist is too fine and the powder scatters.

(2) The powder comes off the skin.

(3) The antiperspirant effect is difficult to maintain.

Further, currently used propellants are mixtures of Freon-11, Freon-12, Freon-114, LPG, etc.
Its use is prohibited except for essential products such as pharmaceuticals.

[0008] Accordingly, the present applicant has solved the above drawbacks, and has restricted the use of Freon-11, Freon-12 and Freon-114 in the United States as described above.
Has developed a safe aerosol antiperspirant that meets current Japanese legal regulations without the use of
No. 63).

[0009]

However, although the above-mentioned aerosol antiperspirant is safe enough to be used, it can substantially satisfy safety standards in a flame length test for those used on the human body. As a result of intensive studies conducted by the present inventors to develop a safer human body aerosol product, the inventors have found a valve capable of manufacturing such a safer human body aerosol product. <br> Thus, the present invention has been completed.

[0010]

That is, according to the present invention , a stem hole diameter is 0.4 to 1.0 mm, a housing lower hole diameter is 0.6 to 2.0 mm, and a vapor tap hole diameter is 0.6 to 2.0 mm.
A 2.0 mm, about the bar <br/> Le Bed housing under pore diameter is used for human body Eyazoru product is under vapor tap hole diameter or less.

[0011]

Operation and Examples Although there is no legal regulation on the current safety standards for eazol products, the flame length in a flame length test must be less than 25 cm for those that are practically used on the human body. For the human body-use aerosol product of the present invention
The valve to be inserted has a stem hole diameter of 0.4 to 1.0 mm,
Lower housing pore size 0.6～2.0Mm, a vapor tap hole diameter 0.6～2.0Mm, since the housing under pore size of under vapor tap hole diameter or less, safety for human body Eyazoru products using the valve The criteria are satisfied.

When the stem hole diameter is less than 0.4 mm, the powder cannot be sprayed due to clogging, and when it exceeds 1.0 mm, the flame length in a flame length test is less than 25 cm. 0.4 to 1.0 mm, especially 0.5 to 1.0.
0 mm.

The diameter of the housing pilot hole is 0.6 m.
If it is less than m, it will not be possible to spray due to clogging of the powder, or it will not be possible to obtain an appropriate spray state. If it exceeds 2.0 mm, a large amount of contents will be sprayed when used. Therefore, it is difficult to reduce the flame length to less than 25 cm, so that it is 0.6 to 2.0 mm, especially 1.0 to 1.75 mm.

The vapor tap hole diameter is 0.6
If it is less than mm, the contents will be jetted vigorously at the time of use, so as to cause pain on the skin,
It is difficult to make the flame length less than 25 cm, and if it exceeds 2.0 mm, it becomes difficult to spray the whole amount, so that 0.6 to 2.0 mm, especially 1.0 to 1.0 mm
2.0 mm.

Further, in order to prevent the flame length from exceeding 25 cm and to prevent the contents from being vigorously jetted during use, it is necessary that the diameter of the lower housing hole be smaller than the diameter of the vapor tap hole.

The present invention is not limited by the shape and the like as long as each of the various hole diameters indicates a diameter and has substantially the same sectional area.

[0017] For the human body-based aerosol product using the valve of the present invention, for example, a drug having an antiperspirant effect, powder, and these auxiliaries are used as active ingredients, and a combustible liquefied gas is used as a propellant. Can be

[0018] agent having the antiperspirant effect, in addition to aluminum chlorohydrate, for example, aluminum phenol sulphonate and the like.

[0019] The powder, in addition to talc, such as kaolin, bentonite and the like.

Incidentally, aluminum chlorohydrate also functions as a powder.

[0021] As the auxiliary agent, such as active agents and powder dispersing agents.

Each of the above-mentioned components does not function by itself, but performs a complex function related to each other.
Although classified as described above, it is rather difficult to simply classify each component. Therefore, it is considered that it is preferable to collectively treat the active ingredients as active ingredients in the Eyazole product.

[0023] The amount of active ingredient 3-15% (wt%, hereinafter the same) are preferred, particularly preferably 5 to 12
%. When the amount of the active ingredient is less than 3%, the antiperspirant effect decreases, and when the amount is more than 15%,
Too much powder, too much activator or powder dispersant, which is likely to cause stickiness, and it can be very powdery or wet due to the excess of both. Further, an extreme antiperspirant effect is exerted too much, and neither is preferable.

[0024] can be used as the propellant for example inflammable liquefied gas, Examples of the inflammable liquefied gas, such as dimethyl ether, the like liquefied petroleum gas and the like, can be particularly blended dimethyl ether, the valve of the present invention Is one of the major factors in the use of EAZOLE products for human body . One of the reasons is that when dimethyl ether is used, the redispersibility of the active ingredient in the Eyazole product is remarkably improved. Methylene chloride is not preferable because it has a peculiar smell and irritates the skin. Pentane is also good in terms of the evaporation rate and latent heat of evaporation, but is not preferred because of its high flammability.

[0025] The amount of the dimethyl ether is preferably from 5-50% in the propellant, particularly preferably 10 to 45%
It is. When the amount of dimethyl ether is less than 5%, redispersibility tends not to be sufficiently exhibited. When the amount is more than 50%, not only an appropriate injection state cannot be obtained, but also The feeling of use tends to be poor.

[0026] The propellant is a gauge pressure at 25 ° C. is blended so that 1~2.5kg / cm ^2. Thus, the gauge pressure at 25 ° C. is 1 to 2.5 kg /
cm ² means that the gauge pressure at 25 ° C. is 1 kg
For a gas smaller than / cm ² , the gas amount needs to be relatively increased, and a gauge pressure at 25 ° C. of 2.5
This is because if the gas is larger than kg / cm ² , it is difficult to handle or an appropriate spray state cannot be obtained, which is not preferable.

[0027] The gauge pressure in the 25 ℃ 1~2.
Examples of the combustible liquefied gas used for controlling the pressure to 5 kg / cm ² include liquefied petroleum gas (LPG). The amount of such combustible liquefied gas is 50-95%
, And particularly preferably 55 to 95%. When the amount of the flammable liquefied gas is less than 50%, the state of the mist becomes coarse and the feeling of use is inferior.
The attachment of the active ingredient tends to be very poor.

As described above, according to the aerosol product for human body using the valve of the present invention, the above-mentioned drawbacks of the conventional aerosol product are improved, and the safety standards in the flame length test for those used for human body are satisfied. In addition to excellent safety, when a relatively dry solvent and a propellant with a moderately high pressure are used, a suitable mist state is created to prevent powder scattering and It is possible to prevent the powder from peeling off the skin, to maintain the antiperspirant effect and the like, and to remarkably improve the redispersibility during use.

[0029] As for human body Eyazoru product using the valve of the present invention has been described with the type blended powder, in a type that does not blended powder in which Kiku of immediate applications.

Next, the present invention is applied to the aerosol product for human body of the present invention .
The valve to be used will be described in detail with reference to examples and comparative examples.

Examples 1 to 5 Each composition was prepared as shown in Table 1 and each test was carried out on an aerosol product for human body using a valve shown in Table 1. Table 1 shows the results.

[0032] are prepared in the composition of the components shown in Comparative Example 1 in Table 1, were subjected to the test for a commercially available for human body Eyazoru product had use the valve shown in Table 1. Table 1 shows the results.

Here, Examples 1 to 5 and Comparative Example 1 are of a type in which powder is blended.

From Table 1, it can be seen that the aerosol product for human body using the valve of the present invention has a small flame length in the flame length test, is excellent in safety, and shows good results in all tests. You can see that there is. On the other hand, commercially available for human body Eyazoru products of the type blended powder, it can be seen that does not pass the test of all.

The evaluation of the test results in Table 1 was based on the following criteria.

：: good good Δ: slightly poor ×: bad

[0037]

[Table 1]

[0038]

For human body Eyazoru products using a valve of the present invention, according to the present invention is, Ru der that has excellent especially safety. Therefore, an aerosol product for human body using the valve of the present invention can be suitably used, for example, as an aerosol antiperspirant.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification code FI A61K 9/12 C09K 3/30 C09K 3/30 B65D 83/14 B (56) References JP-A-61-165320 (JP, A JP-A-1-272518 (JP, A) JP-A-57-75912 (JP, A) JP-A-3-109316 (JP, A) JP-A-63-68686 (JP, A) JP-A-61-68686 161164 (JP, A) JP-A-59-93001 (JP, A) JP-A-59-84801 (JP, A) Patent 2898316 (JP, B2) JOHNSEN "THE AEROSOL HAND BOOK 2nd EDITION" (1982) WAYNE DORLAND COMPANY p. 165 (58) Field surveyed (Int. Cl. ⁷ , DB name) B05B 9/04 B65D 83/44 A61K ⁷ /00-7/48 A61K 9/12 C09K 3/30

Claims (2)

(57) [Claims] 1. A stem hole diameter of 0.4 to 1.0 mm, a housing pilot hole diameter of 0.6 to 2.0 mm, a vapor tap hole diameter of 0.6 to 2.0 mm, and a housing pilot hole diameter of a vapor tap hole diameter. For human body eazazole products that are below
Valves that are needed. 2. A drug having an antiperspirant effect as an active ingredient,
Powders and their auxiliaries are used, the valve of claim 1, wherein the combustible liquefied gas used et be as propellant.