JP2965864B2 - Chemical liquid container and method of manufacturing the same - Google Patents

Abstract

PURPOSE:To obtain a medical fluid vessel which is completely free from a liquid leak, by a method wherein a lower part end face of a mouth part and an upper part end face of a vessel main body are heated, melted, pressed and welded respectively, the inside of the mouth part is sucked under a decompressed state, an upper wall face of the vessel main body is made to stretch and welded to an inner wall face of the mouth part. CONSTITUTION:A medical fluid vessel is constituted by welding a lower part end face 4 of a cylindrical mouth part 2 made of synthetic resin to an upper part wall face 5 of a baggy vessel main body 3 made of flexible synthetic resin. That is, the lower part end face 4 of the mouth part 2, inner wall face 4a and an upper part wall face 5 of the vessel main body 3 into which a medical liquid is filled are heated and melted respectively and the lower part end face 4 and upper part wall face 5 are welded together by pressing them. Then an opening part 6 within the mouth part 2 is fitted, for example, with an adapter 8 with which a suction device 10 is connected through a tube 9 and a space S within the mouth part 2 is sucked under a decompressed state. The upper part wall face 5a in contact with a space S of the vessel main body 3 is sucked in the direction of the space S, stretched and welded to the inner wall face 4a of the mouth part 2.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a chemical liquid container made of synthetic resin and a method of manufacturing the same. It relates to a manufacturing method.

[0002]

2. Description of the Related Art Chemical liquid containers are usually manufactured by heating and welding a hard mouth formed by injection molding between two flexible synthetic resin sheets. Have been. When the mouth is sealed between the sheets because the shape of the mouth is cylindrical,
In some cases, liquid leaked from the periphery of the welded portion of the mouth to the sheet. In order to prevent liquid leakage, a boat-shaped welded portion of the mouth is also proposed. However, the hardness of the material of the mouth and the sheet is different, and even if it is boat-shaped, the sheet is completely welded. However, it was impossible to completely eliminate the leakage of the liquid because it was difficult.

[0003]

Means for Solving the Problems [1] The present invention provides a method for manufacturing a chemical solution container comprising the following steps. (1) a step of heating and melting the lower end surface of the mouth and the upper wall surface of the container body, (2) a step of pressing and welding the lower end surface of the mouth and the upper wall surface of the container body, and (3) an opening of the mouth. A step of sucking the inside of the mouth under reduced pressure by a suction device attached to the container, extending the upper wall surface of the container body, and welding the inner wall surface of the container, (4) attaching a rubber stopper to the opening, and capping the rubber stopper. The process of capping,

[2] The present invention provides a method for manufacturing a chemical solution container comprising the following steps. (1) a step of extruding a heat-melting tube from an extrusion die, (2) a step of welding a mouth having a lower end face heated and melted to the heat-melting tube, and (3) a suction device attached to the opening of the mouth. Sucking the tube under reduced pressure, extending the upper wall surface of the container body, and welding the inner wall surface of the mouth, (4) sealing the tube to a predetermined length, and then fusing (or fusing simultaneously with the sealing) (5) attaching a rubber stopper to the mouth and covering the rubber stopper with a cap;

[3] The present invention provides a method for manufacturing a chemical solution container comprising the following steps. (1) a step of heating and melting the lower end surface of the mouth and the upper wall surface of the container body, (2) a step of pressing and welding the lower end surface of the mouth and the upper wall surface of the container body, and (3) from the inside of the container body. A step of pressing the upper wall surface of the container body by a pressing jig to stretch and weld it to the inner wall surface of the mouth; (4) attaching a rubber stopper to the mouth and covering the rubber stopper with a cap; 5) a step of sealing after filling the medicinal solution from the bottom of the container body;

[4] The present invention provides a method for manufacturing a chemical solution container comprising the following steps. (1) a step of extruding a heat-melted tube from an extrusion die; (2) a step of welding a mouth having a lower end face heated and melted to the heat-melted tube; (3) an upper wall surface of the tube by a pressing jig from inside the tube. Pressing and stretching to weld to the inner wall surface of the mouth, (4) sealing the tube to a predetermined length, and then fusing (or fusing at the same time as sealing); (5) rubber stopper at the mouth Attaching a cap to the rubber stopper,

[5] The present invention provides a method for manufacturing a chemical solution container comprising the following steps. (1) a step of extruding a heat-melting tube from an extrusion die; (2) a step of cooling and folding the heat-melting tube; (3) a step of heating and melting the lower end surface of the mouth and the upper wall surface of the container body; ) A step of pressing and welding the lower end surface of the mouth and the upper wall surface of the container body; (5) suctioning the inside of the mouth to a reduced pressure by a suction device attached to the opening of the mouth portion, and extending the upper wall surface of the container body. Welding the inner wall surface of the mouth, (6) attaching a rubber stopper to the mouth, and covering the rubber stopper with a cap, (7) filling the tube with a chemical solution, (8) attaching the tube to the tube. After sealing to a predetermined length, fusing (or fusing at the same time as sealing),

[6] In the present invention, the upper wall 5 of the container body 3 is provided.
, The lower end face 4 of the mouth 2 on which the inner projection 7 is formed is welded.
And the upper wall of the container body 3 in contact with the space S inside the mouth 2
The surface 5a is extended into the space S to form the diaphragm 11,
The outer peripheral side surface of the upper wall surface 5a is larger than the inner surface protruding portion 7.
The lower portion is welded to the inner peripheral side surface of the mouth portion 2 and the upper portion of the mouth portion 2 is welded.
A rubber stopper 12 is attached to the opening 6 of the
The top surface of the upper wall surface 5a and the rubber
Chemical volume in which the space S is formed between the bottom surfaces of the stoppers 12
Provide a container.

[0009]

FIG. 1 is a schematic view of a chemical solution container 1 (FIG.
The liquid medicine container 1 is constructed by welding a lower end surface 4 of a rigid or semi-rigid synthetic resin cylindrical mouth portion 2 to an upper wall surface 5 of a flexible synthetic resin bag-shaped container main body 3 (arrow view). Is done.
Next, an example of a method for manufacturing the chemical solution container 1 will be described. As shown in FIG. 3, the lower end face 4 and the inner wall face 4a of the mouth 2 and the upper wall face 5 of the container body 3 filled with the chemical are heated and melted, respectively, and the lower end face 4 and the upper wall face 5 are pressed and welded. As shown in FIG. 4, for example, an adapter 8 is attached to the opening 6 of the mouth 2, a suction device 10 is connected to the adapter 8 via a tube 9, and the space S in the mouth 2 is sucked to a reduced pressure. The upper wall surface 5a of the container body 3 which is in contact with the space S is sucked in the direction of the space S, extends and fuses with the inner wall surface 4a of the mouth portion 2. Mouth 2
An inner surface projection 7 is formed on the inner surface of the surface S to prevent the end surface 5a in contact with the space S from being sucked into the space S more than necessary and extended.

Since the upper wall surface 5a in contact with the space S functions as the diaphragm 11, it is necessary to reduce the puncture resistance of the needle and to have a strength to maintain liquid tightness as a container. The extension area of the upper wall surface 5a in contact with the space S is 2 to 6
It is preferable that the thickness after stretching is 100 to 200 μm. If the thickness of the container main body 3 before stretching (300 to 600 μm) is too thick, it is difficult to break through with a needle, and if the thickness is 100 μm or less due to excessive stretching, it is easily broken and plays a role as the diaphragm 11. Is not possible. The inner diameter of the mouth 2 is 10 to 50 m
m. If it is 10 mm or less, the volume of the space S is small, and it is difficult to generate a negative pressure enough to extend the upper wall surface 5a in contact with the space S. If it is 50 mm or more, the stretching ratio of the upper wall surface 5a in contact with the space S becomes large and the wall thickness becomes thin, so that the strength as the diaphragm 11 cannot be maintained. Finally, the adapter 8 and the suction device 1 from the mouth 2
The rubber plug 12 is attached to the opening 6 as shown in FIG. 5, and the rubber stopper 12 is covered with a cap 13 as shown in FIG.

FIG. 6 is a schematic view showing an embodiment of another manufacturing method of the chemical liquid container 1. As shown in FIG. The manufacturing method of FIG.
This is a method of welding the mouth portion 2 where the lower end face 4 is heated and melted while extruding the heat melting tube 23 constituting the container body 3 from zero. Further, similarly to Japanese Patent Publication No. Hei 4-10825, a chemical liquid injection line 24 is disposed so as to penetrate the extrusion die 20 and is filled with a chemical liquid.

The mouth 2 is attached to the distal end of the vacuum tube 22 of the suction device 10, and the heated and melted lower end surface 4 of the mouth 2 is pressed against the heated and melted tube 23 so that the inside of the outlet of the extrusion mold 20 is heated and melted. The lower end face 4 of the mouth portion 2 is welded from both the pressure plate 21 provided and the vacuum tube 22 of the suction device 10 so that the heat melting tube 2
3 can be welded. Subsequently, the inside of the mouth 2 is suctioned by the suction device 10 to reduce the pressure, and the upper wall surface 25a of the tube 23 that comes into contact with the space S of the mouth 2 is stretched.
Is welded to the inner wall surface 24a. Subsequently, as shown in FIG. 7, the tube 23 is sealed in a predetermined shape by a seal mold 25, and then melted (or melted at the same time as the seal) by a melting mold 26 to obtain the shape of the container body 3. Finally, a rubber stopper 12 is attached to the opening 6 of the mouth 2 and a cap 13 is attached to the rubber stopper 12 as in FIG.

FIGS. 8 and 9 are schematic views showing another embodiment of the method for manufacturing the chemical solution container 1. FIG. 3 to 5, instead of depressurizing and suctioning the space S of the mouth 2, the pressing jig 27 presses the upper wall surface 5 a of the container body 3 from inside the container body 3 and extends the inner wall surface in the mouth 2. 4a and upper wall 5a
Is a method of welding. After the rubber stopper 12 and the cap 13 are covered as shown in FIG. 5, a chemical is filled and sealed from the bottom of the container body 3 (the other details are substantially the same as FIGS. Omitted). FIG. 10 is a schematic view showing an embodiment of another manufacturing method of the chemical solution container.
6 and 7, instead of welding from both the crimping plate 21 and the vacuum tube 22 of the suction device 10 provided inside the outlet of the heating and melting tube 23 of the extrusion mold 20, the inside of the heating and melting tube 23 of the extrusion mold 20 is inside. The provided pressing jig 28 (attached to the jig fixing tool 29,
Direction)) and the jig 22a which clamps the mouth portion 2 are pressed, and the upper wall surface 25a of the tube 23 is stretched by pressing the upper wall surface 25a of the tube 23 from the inside of the tube 23 from the inside of the tube 23. 2 inner wall surface 24a and upper wall surface 25
8 and 9, and the mouth portion 2 is welded to the heat-melting tube 23 (the other portions are substantially the same as those in FIGS. 6 and 7, and therefore detailed description is omitted. Further, in the present invention, after the heat-melting tube 23 extruded from the extrusion die 20 is once cooled and folded, the mouth portion 2 can be welded by the means shown in FIGS. After the tube 23 is filled with the chemical solution, the container 23 can be sealed in a predetermined shape and melted (or melted at the same time as the seal) as in FIG.

[0014]

Effects of the Invention

(1) Since the upper wall surface 5a of the container body 3 is welded to the lower end surface 4 and the inner wall surface 4a of the mouth 2, liquid tightness is enhanced. (2) Since the diaphragm 11 can be formed to be thin, the puncture resistance of the needle of the infusion set can be reduced (from 50 to 150).
g / cm ² ). (3) The welding of the mouth portion 2 to the container body 3 is easy, and expensive sealing equipment as in the related art is unnecessary. (4) It is not necessary to provide a liquid contact cap in the space of the mouth 2 communicating with the rubber stopper 12 and the container body 3, and the rubber stopper 12 does not need to be laminated, so that the number of parts can be reduced. The cost can be significantly reduced by the synergistic effect with the above (3).

[Brief description of the drawings]

FIG. 1 is a schematic diagram of a chemical solution container.

FIG. 2 is a view taken in the direction of arrow A in FIG. 1;

FIG. 3 is a schematic diagram of a mouth connecting process.

FIG. 4 is a schematic diagram of a mouth connecting process.

FIG. 5 is a schematic diagram of a mouth connecting process.

FIG. 6 is a schematic view showing another embodiment of the mouth connecting step.

FIG. 7 is a schematic view showing another embodiment of the mouth connecting step.

FIG. 8 is a schematic view showing another embodiment of the mouth connecting step.

FIG. 9 is a schematic view showing another embodiment of the mouth connecting step.

FIG. 10 is a schematic view showing another embodiment of the mouth connecting step.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 Chemical container 2 Mouth 3 Container main body 4 Lower end face of mouth 4a, 24a Internal wall surface of mouth 5 Upper wall surface of container body 5a Upper wall surface of container body in contact with space S of mouth 25a Contact with space S of mouth Upper wall surface of tube 6 Opening of mouth 7 Inner surface projection 8 Adapter 9 Tube 10 Suction device 11 Diaphragm 12 Rubber stopper 13 Cap 20 Extrusion mold 21 Crimping plate 22 Vacuum tube 22a Jig 23 Heat-melting tube 24 Chemical liquid injection line 25 Sealing die 26 Fusing die 27, 28 Pressing jig 29 Jig fixture

Claims (6)

(57) [Claims] 1. A method for producing a chemical solution container, comprising the following steps. (1) a step of heating and melting the lower end face of the mouth and the upper wall face of the container body, (2) a step of pressing and welding the lower end face of the mouth and the upper wall face of the container body, and (3) an opening of the mouth. Suctioning the inside of the mouth to a reduced pressure by a suction device attached to the container, extending the upper wall surface of the container body, and welding the inner wall surface of the container, and (4) attaching a rubber stopper to the opening and capping the rubber stopper. The process of capping, 2. A method for producing a chemical solution container, comprising the following steps. (1) a step of extruding a heat-melting tube from an extrusion die;
(2) a step of welding a lower end surface of the container to a heat-melting tube by welding; (3) a suction device attached to the opening of the opening sucks the inside of the opening at a reduced pressure to stretch the upper wall surface of the container body. (4) a step of sealing the tube to a predetermined length and then fusing (or fusing at the same time as the sealing); (5) attaching a rubber stopper to the opening, A process of capping the stopper with a cap, 3. A method for manufacturing a chemical solution container, comprising the following steps. (1) a step of heating and melting the lower end surface of the mouth and the upper wall surface of the container body, (2) a step of pressing and welding the lower end surface of the mouth and the upper wall surface of the container body, and (3) from the inside of the container body. A step of pressing the upper wall surface of the container body by a pressing jig to stretch and weld it to the inner wall surface of the mouth, (4) attaching a rubber stopper to the mouth, and covering the rubber stopper with a cap, 5) a step of sealing after filling the medicinal solution from the bottom of the container body; 4. A method for producing a chemical liquid container, comprising the following steps: (1) a step of extruding a heat-melting tube from an extrusion die;
(2) A step of welding the lower end surface of the tube to the heat-melted tube by welding, and (3) Pressing and stretching the upper wall surface of the tube from the inside of the tube with a pressing jig, and welding the inner wall surface of the mouth. (4) a step of fusing (or fusing at the same time as sealing) after sealing the tube to a predetermined length, (5) a step of attaching a rubber stopper to the mouth and covering the rubber stopper with a cap, 5. A method for producing a chemical solution container, comprising the following steps: (1) a step of extruding a heat-melting tube from an extrusion die;
(2) a step of cooling and folding the heat-melting tube;
(3) a step of heating and melting the lower end surface of the mouth and the upper wall surface of the container body, (4) a step of pressing and welding the lower end surface of the mouth and the upper wall surface of the container body, and (5) an opening of the mouth. A step of sucking the inside of the mouth at a reduced pressure by a suction device attached to the container, extending the upper wall surface of the container body, and welding the inner wall surface of the container, (6) attaching a rubber stopper to the mouth, and capping the rubber stopper. (7) filling the tube with a drug solution, (8) sealing the tube to a predetermined length,
A process of fusing (or fusing simultaneously with the seal), 6. An inner projection 7 on the upper wall 5 of the container body 3.
Weld the lower end face 4 of the mouth 2 formed with
The upper wall surface 5a of the container body 3 in contact with the space S
S to form a diaphragm 11, and the upper wall surface 5a
The outer peripheral side surface of the opening 2 is lower than the inner surface protruding portion 7.
Is welded to the inner peripheral side surface of the
The stopper 12 is attached, and the cap 13 is covered with the rubber stopper 12.
The top surface of the upper wall surface 5a and the bottom surface of the rubber stopper 12
A medicine characterized in that the space S is formed therebetween.
Liquid container.