JP2944358B2 - Autonomic nervous activity evaluation device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an autonomic nervous activity evaluation apparatus for evaluating an autonomic nervous system activity related to maintenance of homeostasis of a living body. The activity of the autonomic nervous system changes every moment depending on the living environment, work environment, work load and the like. This change is a response to adapt to environmental stimuli and mental stress. However, if the stimulation or load is strong or persistent, the adaptive function of the living body is modulated, and adverse effects on the mind and body such as stress-related diseases appear. INDUSTRIAL APPLICATION This invention can be used for evaluation of the influence which a work environment, a living environment, and a work load exert on a human, and the state of the mental and physical fatigue and stress of a worker. The evaluation results serve as effective guidelines for improving the work environment and living environment from the viewpoint of maintaining physical and mental health, work plans, and the like. That is, effective guidelines can be provided in public health, architecture, and the like.

Further, since the present invention enables real-time evaluation of autonomic nervous system activity, it can also be used in a manner of evaluating changes in physical and mental states during work and issuing a break instruction or warning to the worker. Becomes For example, it is possible to evaluate the autonomic nervous system activity during VDT work or driving a car in real time, instruct a break or issue a warning when falling asleep, and provide a human interface or safety device that adapts to the state of the living body. Available. In addition, since the recorded autonomic nerve index values can be evaluated, the autonomic nerve index value data over a long period of time can be evaluated and analyzed after recording, and the autonomic nerve index value data obtained by a portable data collection device can be evaluated. It can also be used for evaluation and analysis of This allows
When evaluating mental and physical fatigue and stress in everyday situations,
The burden on the measurement target is reduced.

[0003]

2. Description of the Related Art As a conventional technique for evaluating autonomic nervous activity, there is an autonomic nervous function test method used in the medical field. Autonomic nervous function tests are roughly divided into physiological tests, pharmacological tests, biochemical tests, pathological tests,
There is an image inspection. Physiological tests obtain physical measurements such as bioelectric phenomena and blood pressure. In pharmacological tests, the reaction of a living body when a drug is injected is evaluated.
In a biochemical test, blood is collected to evaluate the hormone concentration and the like in the blood, and in a pathological test, the tissue of a living body is collected to check for the presence or absence of a lesion. The image inspection includes MRI (nuclear magnetic resonance imaging), X-ray CT (X-ray cross-sectional image), and the like. The living tissue is visualized using magnetism or X-rays to check for the presence of a tissue lesion.

[0004] In fields such as psychology and ergonomics, attempts have been made to quantify fatigue and work stress using autonomic nerve indices. For example, a method of measuring a mental load using an electrocardiogram (for example, “An attempt to evaluate a mental workload when creating a document by a computer (2)”, Akashi et al.
Proceedings of the 6th Human Interface Symposium, pp357-362. ) Etc. have been proposed.

[0005]

Among the conventional methods for evaluating autonomic nervous activity, the autonomic nervous function test method is a test method for medical sites and is used to determine whether the autonomic nervous function is normal or abnormal. Therefore, evaluation of autonomic nerves in everyday situations,
In particular, it is difficult to use it as it is for evaluating autonomic nervous activity within the normal range. In addition, the normal value or normal range of the autonomic nervous index value differs for each healthy individual,
The level of the autonomic nervous index value at a certain time must be determined based on the normal value or normal range of one individual.

[0006] There is no example of a method that has been tried in the fields of psychology, ergonomics, and the like in consideration of the above-described method of coping with individual differences.

[0007] In any field, evaluation of autonomic nervous activity in real time has not been realized, and the burden on the subject and the examiner is not small.

It is an object of the present invention to provide a device which can evaluate autonomic nervous activity according to individual differences, which has not existed in the past.

Another object of the present invention is to provide an apparatus for realizing daily autonomic nervous activity evaluation for healthy individuals.

Still another object of the present invention is to provide an apparatus for evaluating autonomic nervous activity which realizes evaluation of autonomic nervous activity in real time, thereby reducing the burden on the subject and the examiner.

Still another object of the present invention is to provide an autonomic nervous activity evaluation apparatus which can be used for a human interface which presents information while adapting to the activity state of the autonomic nervous system of an individual.

[0012]

According to a first aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein time series data of an autonomic nervous index value is used as input data, and autonomic nervous index value data is output as it is. A reference value calculation unit that obtains the latest maximum value and minimum value of the autonomic nerve index value and outputs them as an autonomic nerve activity reference value, and an autonomic nerve index value data and an autonomic nerve activity reference value output by the reference value calculation unit And an autonomic nervous activity evaluator that evaluates the activity of the autonomic nervous system in real time and outputs an autonomic nervous activity evaluation value.

According to a second aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein time-series data of an autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and A maximum value and a minimum value are obtained for the index values, and an intra-section reference value calculation unit that outputs them as an autonomic nerve activity reference value; an autonomic nerve index value data and an autonomic nerve activity reference value output by the intra-section reference value calculation unit And an autonomic nervous activity evaluator that evaluates the activity of the autonomic nervous system in real time and outputs an autonomic nervous activity evaluation value.

According to a third aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein a data recording / reproducing section for recording all the time-series data of the input autonomic nervous index value, reproducing and outputting the data at the time of evaluation, The time series data of the autonomic nervous index value output by the data recording / reproducing unit is used as input data, the autonomic nervous index value data is output as it is, and the maximum and minimum values of the autonomic nervous index value are obtained. A reference value calculation unit that outputs a value, and an autonomic nervous activity that evaluates the autonomic nervous system activity from the autonomic nervous index value data and the autonomic nervous activity reference value output by the reference value calculation unit and outputs an autonomic nervous activity evaluation value. And an evaluation unit.

According to a fourth aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein a data recording / reproducing unit which records all time-series data of the input autonomic nervous index values, reproduces and outputs the data at the time of evaluation, The time series data of the autonomic nervous index value output by the data recording / reproducing unit is used as input data, and the autonomic nervous index value data is output as it is, and the maximum value and the minimum value of the autonomic nervous index value within a predetermined time are obtained. An intra-segment reference value calculation unit that outputs as an autonomic nerve activity reference value, and evaluates the autonomic nervous system activity based on the autonomic nerve index value data and the autonomic nerve activity reference value output by the intra-segment reference value calculation unit. An autonomic nervous activity evaluation unit that outputs an activity evaluation value.

According to a fifth aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein time-series data of an autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and the autonomic nervous index value within a predetermined time is output. An average value is calculated for the index value, and the average value calculating section within the section outputs the average value as the autonomic nerve activity reference value. The autonomous nerve index value data and the autonomic nerve activity reference value output from the average value calculating section within the section are autonomously calculated. An autonomic nervous activity evaluation unit that evaluates the activity of the nervous system in real time and outputs an autonomic nervous activity evaluation value.

According to a sixth aspect of the present invention, in the device for evaluating autonomic nervous activity of a living body, a data recording / reproducing section which records all the time series data of the input autonomic nervous index values, reproduces and outputs the data at the time of evaluation, The time series data of the autonomic nervous index value output from the data recording / reproducing unit is used as input data, the autonomic nervous index value data is output as it is, an average value is obtained for the autonomic nervous index value within a predetermined time, and the average value is obtained. An intra-section average value calculating section that outputs as a reference value, and an autonomic nervous activity evaluation value that evaluates the degree of activity of the autonomic nervous system from the autonomic nerve index value data and the autonomic nerve activity reference value output by the intra-section average value calculating section. An autonomic nervous activity evaluation unit that outputs
It is characterized by having.

According to a seventh aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein time series data of an autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and An evaluation criterion value calculating unit that obtains a frequency distribution for the index value and outputs a boundary value that divides the frequency into predetermined steps as an autonomic nervous activity standard; an autonomic nervous index value data and an autonomic nervous activity output by the evaluation criterion value calculating unit An autonomic nervous activity evaluation unit that evaluates the autonomic nervous system activity in real time from a reference and outputs an autonomic nervous activity evaluation value.

According to an eighth aspect of the present invention, in the device for evaluating autonomic nervous activity of a living body, a data recording / reproducing section for recording all the time series data of the input autonomic nervous index value, reproducing and outputting the data at the time of evaluation, The time series data of the autonomic nervous index value output by the data recording / reproducing unit is used as input data, and the autonomic nervous index value data is output as it is, and a frequency distribution is obtained for the autonomic nervous index value within a predetermined time, and the frequency is set to a predetermined level. An evaluation criterion value calculating unit that outputs a boundary value to be divided as an autonomic nervous activity standard, and an autonomic nervous activity standard based on the autonomic nervous index value data and the autonomic nervous activity standard output by the evaluation criterion value calculating unit, An autonomic nervous activity evaluation unit that outputs an autonomic nervous activity evaluation value.

A ninth aspect of the present invention is a device for evaluating autonomic nervous activity of a living body, wherein time series data of an autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and the latest autonomic nervous index value is used. A maximum value or a minimum value, and a reference value calculation unit that outputs them as an autonomic nervous activity reference value, and an activity of the autonomic nervous system from the autonomic nervous index value data and the autonomic nervous activity reference value output by the reference value calculation unit. An autonomic nervous activity evaluation unit that evaluates the degree in real time and outputs an autonomic nervous activity evaluation value.

According to a tenth aspect, in a device for evaluating autonomic nervous activity of a living body, a reference value storage section for storing a range of an autonomic nervous index value as an evaluation criterion of the autonomic nervous activity as a reference value, Autonomic nervous activity that takes time series data of index values as input data, evaluates the activity of the autonomic nervous system in real time by comparing it with a reference value stored in a reference value storage unit, and outputs an autonomic nervous activity evaluation value And an evaluation unit.

According to an eleventh aspect of the present invention, there is provided an apparatus for evaluating autonomic nervous activity of a living body, wherein a test stimulus presenting section for presenting a test stimulus and outputting a stimulus presentation signal before and after the stimulus presentation is provided. With the data as input data, the autonomic nervous index value data is output as it is, and the stimulus presentation signal output by the test stimulus presentation unit is received, and the autonomic nervous system reaction amount is calculated from the autonomic nervous index value when the stimulus presentation signal is received. And an autonomic nervous activity evaluation unit that outputs an autonomic nervous activity evaluation value from the autonomic nervous index value data and the autonomic nervous system reaction amount output by the reaction amount calculation unit. .

[0023]

Since the autonomic nervous activity evaluation apparatus according to the first aspect of the present invention has the reference value calculation unit, it is possible to obtain the latest maximum value and minimum value of the time series data of the input autonomic nerve index value. Can be output together with the time series data of the autonomic nerve index value. This makes it possible to calculate a reference value for evaluating autonomic nervous activity according to individual differences. In addition, by having an autonomic nervous activity evaluation unit,
It is possible to evaluate, in real time, where the autonomic nerve index value at the current time is located within the range of the autonomic nerve index values that the individual can take, according to the individual difference.

Since the autonomic nervous activity evaluation apparatus according to the second invention has an intra-section reference value calculation unit, it obtains the maximum value and the minimum value of the input autonomic nerve index value in a predetermined section of the time-series data. And output them together with the time series data of the autonomic nerve index value. Thereby, it is possible to calculate a reference value for evaluating the autonomic nervous activity at the current time based on the autonomic nervous activity within a certain time, while responding to individual differences. Further, by having the autonomic nervous activity evaluation unit, based on the autonomic nervous activity within a predetermined time, the autonomic nervous index value at the current time is set to any position within the range of the autonomic nervous index value that can be taken by the individual, according to the individual difference. Can be evaluated in real time.

Since the autonomic nervous activity evaluation device of the third invention has the data recording / reproducing unit, it can record and reproduce the autonomic nervous index value. Furthermore, since it has a reference value calculation unit, the maximum value and the minimum value of the time series data of the recorded autonomic nerve index value can be obtained, and these are output together with the recorded time series data of the autonomic nerve index value. be able to. Further, by having the autonomic nervous activity evaluation unit, it is possible to evaluate where the autonomic nervous index value is located in the range of the autonomic nervous index value that can be taken by the individual with respect to the recorded autonomic nervous activity according to individual differences. it can.

Since the autonomic nervous activity evaluation device of the fourth invention has a data recording / reproducing section, it can record and reproduce an autonomic nervous index value. Furthermore, since it has the reference value calculation part in a section, the maximum value and the minimum value in the predetermined section of the time-series data of the recorded autonomic nerve index value can be obtained, and those of the recorded autonomic nerve index value can be obtained. It can be output together with time series data. Thereby, the reference value for evaluating the autonomic nervous activity based on the activity within a certain time of the recorded autonomic nervous index value can be calculated according to the individual difference. Further, by having an autonomic nervous activity evaluation unit, based on autonomic nervous activity within a predetermined time in the recorded data, the autonomic nervous index value is within the range of the autonomic nervous index value that the individual can take while responding to individual differences. You can evaluate where it is located.

Since the autonomic nervous activity evaluation apparatus according to the fifth aspect of the present invention includes the average value calculating section within the section, the average value of the time series data of the input autonomic nerve index value in a predetermined section can be obtained. It can be output together with the time series data of the autonomic nerve index value. Thereby, it is possible to calculate a reference value for evaluating the autonomic nervous activity at the current time based on the autonomic nervous activity within a predetermined time while referring to individual differences. Furthermore, by having an autonomic nervous activity evaluation unit, it is possible to evaluate how much the autonomic nervous index value at the current time is different from the average value based on the autonomic nervous activity within a predetermined time, according to individual differences. it can.

Since the autonomic nervous activity evaluation device of the sixth invention has a data recording / reproducing unit, it can record and reproduce an autonomic nervous index value. Furthermore, since it has an average value calculating section within a section, it is possible to obtain the average value of the recorded autonomic nerve index value time series data in a predetermined section, and to record the average value of the recorded autonomic nerve index value time series data. And can be output. Thereby, the reference value for evaluating the autonomic nervous activity based on the activity within a certain time can be calculated for the recorded autonomic nervous index value, according to the individual difference.

Further, by providing the autonomic nervous activity evaluation unit, the recorded autonomic nervous index value is compared with the average value of the recorded autonomic nervous index value based on the autonomic nervous activity within a predetermined time in the recorded data according to individual differences. You can evaluate whether you are away.

The autonomic nervous activity evaluation apparatus according to a seventh aspect of the present invention includes an evaluation criterion calculation unit, which calculates a reference value based on a frequency distribution in a predetermined section of the time series data of the input autonomic nervous index value. Can be output together with the time series data of the autonomic nerve index value. Thereby, it is possible to calculate a reference value for evaluating the autonomic nervous activity at the current time based on the autonomic nervous activity within a predetermined time while referring to individual differences. Furthermore, by having the autonomic nervous activity evaluation unit, it is possible to evaluate how easily the autonomic nervous index value at the current time appears with reference to the autonomic nervous activity within a predetermined time while responding to individual differences. it can.

Since the autonomic nervous activity evaluation device according to the eighth aspect of the present invention has a data recording / reproducing unit, it can record and reproduce the autonomic nervous index value. Furthermore, by having the evaluation criterion calculating unit, it is possible to calculate a reference value based on the frequency distribution in a predetermined section of the time-series data of the recorded autonomic nerve index value, and to calculate the reference value of the recorded autonomic nerve index value. It can be output together with time series data. Thereby, it is possible to calculate a reference value for evaluating the autonomic nervous activity recorded based on the autonomic nervous activity within a predetermined time while referring to individual differences. Furthermore, by having an autonomic nervous activity evaluation unit, based on the frequency distribution of the autonomic nervous index values within a predetermined time, it is possible to evaluate how easily the recorded autonomic nervous index values are likely to appear while responding to individual differences. can do.

Since the autonomic nervous activity evaluation apparatus according to the ninth aspect has the reference value calculation unit, the latest maximum value or minimum value of the time series data of the input autonomic nerve index value can be obtained. Can be output together with the time series data of the autonomic nerve index value. This makes it possible to calculate a reference value for evaluating autonomic nervous activity according to individual differences. Further, by having an autonomic nervous activity evaluation unit, it is possible to evaluate in real time how far the autonomic nervous index value at the current time is from an upper limit or a lower limit of an autonomic nervous index value that can be taken by an individual according to individual differences. be able to.

An autonomic nervous activity evaluation apparatus according to a tenth aspect of the present invention comprises:
By having a reference value storage unit, an autonomic nerve index value or a range of values serving as an evaluation standard for autonomic nerve activity can be stored as a reference value. By using the time-series data as input data and comparing with the reference value stored in the reference value storage unit, the activity of the autonomic nervous system can be evaluated in real time, and the autonomic nervous activity evaluation value can be output. Thereby, for example, it is possible to evaluate whether the autonomic nervous index value of one individual is larger or smaller than a general autonomic nervous index value, whether or not it is within a normal range, whether or not it is within the range of the value normally shown for one individual, etc. . This is an effective evaluation value for daily health management and the like.

An autonomic nervous activity evaluation apparatus according to an eleventh aspect of the present invention comprises:
Since it has a test stimulus presentation unit, it presents test stimuli,
A stimulus presentation signal can be output before and after stimulus presentation,
Since the reaction amount calculation unit is provided, the time series data of the autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and a stimulus presentation signal output by the test stimulus presentation unit is received. The autonomic nervous system reaction amount can be calculated from the autonomic nervous index value at the time of reception, and since it has an autonomic nervous activity evaluation unit, the autonomic nervous index value data and the autonomic nervous system response output by the reaction amount calculation unit are output. An autonomic nervous activity evaluation value can be output from the quantity.

Thus, the response of the autonomic nerve to the stimulus can be automatically evaluated. In a persistent state such as fatigue, the activity of the autonomic nervous system is easily reflected in the response to the stimulus, so an effective evaluation value is obtained when it is difficult to evaluate the autonomic nervous activity from the autonomic index value or its change alone. It becomes possible.

In addition, an autonomic nervous function test can be performed in real time, so that labor in a clinical autonomic nervous function test can be reduced and the test can be speeded up. This reduces the burden on patients as well as doctors, lab technicians and nurses.

[0037]

Embodiments of the present invention will be described with reference to the drawings.

FIG. 1 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the first invention. This autonomic nervous activity evaluation device takes time series data of the autonomic nervous index value as input data, and outputs the autonomic nervous index value data as it is,
A reference value calculation unit 1 that obtains the latest maximum value and minimum value of the autonomic nerve index value and outputs them as an autonomic nerve activity reference value.
And an autonomic nervous activity evaluation unit 2 that evaluates the autonomic nervous system activity in real time from the autonomic nervous index value data and the autonomic nervous activity reference value output by the reference value calculation unit 1 and outputs an autonomic nervous activity evaluation value. Have.

The time series data 900 of the autonomic nervous index value is input to the reference value calculation unit 1. FIG. 2 shows the internal configuration of the reference value calculation unit 1 and the flow of signals. The input signal 900 is branched into two systems, one of which is sent to the autonomic nervous activity evaluation unit 2 as it is. The other input signal is connected to the maximum / minimum value detection unit 11. The maximum / minimum value detection unit 11 calculates an autonomic nerve index value from the start of the operation of the device to the current time.
The maximum value Xmax (T) and the minimum value Xmin (T) are detected. They are,

[0040]

(Equation 1)

Is defined as follows. Here, X (t) is the autonomic nerve index value at time t, and T is the current time. The reference value calculation unit 1 sets Xmax (T) and Xmin (T) as a reference value 901, and sends the reference value 901 to the autonomic nervous activity evaluation unit 2.

FIG. 3 shows an example of calculation of the autonomic nerve activity evaluation value 902 in the autonomic nerve activity evaluation section 2. The autonomic nervous activity evaluator 2 includes an autonomic nervous index value 900 and a reference value calculator 1.
, The autonomic nervous index value X (T) at the current time T, the latest maximum value Xmax (T)
And the minimum value Xmin (T), for example,

[0043]

(Equation 2)

Then, Y (T) is output as the autonomic nerve activity evaluation value 902.

The evaluation value Y of the autonomic nerve activity in this example
(T) is a value indicating how much the autonomic nerve index value of one individual at the current time T is located within a possible range. Suppose Xmax (T) is 1.0 and Xmin (T)
Is 0.0, the autonomic nervous activity state of the individual at the current time T can be evaluated as a value between 0.0 and 1.0.

The input signal branching inside the reference value calculation unit 1 can also be realized by a method of splitting the signal into two systems before being input to the reference value calculation unit 1. In this case, FIG.
Is as shown in FIG.

Physiological indices that reflect the activity of the autonomic nervous system include pupil area, blood flow, heart sound chart, electrocardiogram, electrocardiogram, heart rate, heartbeat interval, heartbeat fluctuation, fingertip pulse wave amplitude, blood pressure, saliva secretion , Salivary secretion rate, respiratory flow rate, expiratory component, skin resistance value, gastric juice pH, body temperature, respiratory rate, sweating rate, sweating rate, electroencephalogram, magnetoencephalogram, blood sugar level, blood hormone concentration, and the like. Here, an actual use form including a measurement portion of an autonomic nerve index value and a display portion of an evaluation result will be described, taking as an example a case where the fingertip pulse wave amplitude is used as input data.

The fingertip pulse wave can be obtained as a voltage change by using a pulse pickup (for fingertips) 45261 manufactured by NEC Corporation and a bioelectricity amplifier such as a bioelectric amplification unit 1253A. it can. This voltage change is measured by an ADX manufactured by Canopus Electronics Co., Ltd. attached to a personal computer such as a PC-9801 manufactured by NEC Corporation.
-Measured via an A / D converter board such as -98E,
For example, by making the difference between the maximum value and the minimum value of the voltage of the pulse wave signal for 2 seconds as the pulse wave amplitude value, the fingertip pulse wave amplitude value which is an autonomic nerve index value can be obtained. This fingertip pulse wave amplitude value is connected to the reference value calculation unit 1 as an input signal, and the functions of the above-described reference value calculation unit 1 and autonomic nervous activity evaluation unit 2 are described and operated as a program. By displaying the evaluation value 902 on a CRT or the like, it becomes possible to observe the evaluation result of the autonomic nervous activity in real time.

Next, FIG. 5 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the second invention. The difference from the autonomic nervous activity evaluation device of the first invention is that the reference value calculation unit 1 is replaced by the intra-section reference value calculation unit 3. The intra-section reference value calculation unit 3 receives the time series data of the autonomic nerve index value as input data, outputs the autonomic nerve index value data as it is, and calculates the maximum value and the minimum value of the autonomic nerve index value within a predetermined time. , And output them as autonomic nervous activity reference values.

FIG. 6 shows the internal configuration of the intra-section reference value calculation unit 3.

The time series data 900 of the autonomic nerve index value input to the intra-section reference value calculation section 3 is first branched into two systems. One of the time series data of the branched autonomic nerve index values is sent to the autonomic nerve activity evaluation unit 2 as it is, and the other is connected to the section setting unit 31. The section setting unit 31 converts the input signal 900 into the maximum value minimum value detection unit 3 at the start of the reference value detection based on the reference value detection section setting procedure incorporated in advance.
2 and disconnects the input signal 900 and the maximum / minimum value detection unit 32 after a predetermined time has elapsed from the start of the reference value detection. FIG. 7A shows a state where the input signal 900 is connected to the maximum / minimum value detection unit 32, and FIG. 7B shows a state where the input signal 900 is disconnected. When the reference value detection time is determined to be W seconds, for example, (a) A seconds after the start of the operation of the device, (b) every B seconds during the operation of the device, c) The time is set in advance, or (d) W seconds before the latest time.

In the case of (a), the operation start time is set to t = 0,
The input signal 900 is connected to the maximum / minimum value detection unit 32 for W seconds from t = A, and when t = A + W, the input signal 900 is input.
A reference value detection section setting procedure for opening the 0 and maximum / minimum value detection sections 32 is built in. That is, the time-series data sent to the maximum value minimum value detection unit 32 is X (t) that satisfies A ≦ t ≦ A + W.

At this time, the maximum value Xmax and the minimum value Xmin detected by the maximum value / minimum value detection section 32 are

[0054]

(Equation 3)

Is as follows. Autonomous nerve activity evaluation using these as reference values is suitable when assessing fatigue after a certain period of time from the start of work, or when wanting to evaluate the state of autonomic nerve activity after a certain period of time after presentation of stimulus or medication. Conceivable.

In the case of (b), the operation start time is set to t = 0,
When t = B, the input signal 900 is converted to the maximum value / minimum value detection unit 32.
Connect to As soon as t = B + W, the input signal 90
0 and the maximum / minimum value detection unit 32 are released. Thereafter, when n is a natural number and nB ≦ t ≦ nB + W, the input signal 900 is used.
And the maximum value / minimum value detection unit 32 are connected, and at other times, the input signal 900 and the maximum value / minimum value detection unit 32 are repeatedly opened. The procedure for setting the reference value detection section as described above is built in. In this case, the time series data sent to the maximum value minimum value detection unit 32 is nB ≦ t ≦ nB + W (n is a non-negative integer)
X (t) that satisfies

At this time, the maximum value Xmax and the minimum value Xmin detected by the maximum value / minimum value detection section 32 are

[0058]

(Equation 4)

Is as follows. As a case where the evaluation of the autonomic nervous activity using these as reference values is suitable, a case where the autonomic nervous activity and fatigue are regularly evaluated during the work may be considered.

In the case (c), the operation start time is set to t = 0,
Assuming that the specified time for detecting the maximum value and the minimum value is t = Tp, t =
At the time of Tp, the input signal 900 is connected to the maximum / minimum value detection unit 32. As soon as t = Tp + W, the input signal 90
0 and the maximum / minimum value detection unit 32 are released. The procedure for setting the reference value detection section as described above is built in. In this case, the time series data sent to the maximum value minimum value detection unit 32 is Tp ≦
X (t) that satisfies t ≦ Tp + W. At this time, the maximum value Xmax and the minimum value X detected by the maximum value minimum value detection unit 32
min is

[0061]

(Equation 5)

Is obtained. Of course, the detection start designated time is set to T
It is also possible to prepare a plurality of such as p1 and Tp2. When evaluating autonomic nervous activity considering biological rhythm,
It is necessary to output a plurality of evaluation results at fixed times, such as before and after a meal and before going to bed, and such a setting at the time of detecting a reference value is effective.

In the case of (d), as shown in FIG.
Data storage type maximum / minimum value detection unit 3 capable of always storing time series data of autonomic nerve index values from TW to current time T
3, the stored time-series data, ie, T-
Maximum value Xmax for X (t) satisfying W ≦ t ≦ T
(T) and the minimum value Xmin (T) are detected. At this time, the maximum value X detected by the data storage type maximum value minimum value detection unit 33
max (T) and minimum value Xmin (T)

[0064]

(Equation 6)

Is obtained. As a case where the autonomic nervous activity evaluation using these as reference values is suitable, there is a case where the autonomic nervous activity state is constantly monitored during work.

Next, FIG. 9 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the third invention. The autonomic nervous activity evaluation device differs from the autonomic nervous activity evaluation device of the first invention in that the data recording / reproducing unit 4 is added and the data time is the recording time. The data recording / reproducing unit 4 records all the time series data of the input autonomic nerve index value, and reproduces and outputs the data at the time of evaluation.

The data recording / reproducing section 4 records the autonomic nervous index value 900 using a data recorder or a magneto-optical disk device manufactured by TEAC, or a magnetic recording device such as PC-HD300 manufactured by NEC Corporation, and the like. It can be realized by playing back at the time of activity evaluation.

The autonomic nerve index value 911 output from the data recording / reproducing section 4 at the time of reproducing is input to the reference value calculating section 1. The reference value calculation unit 1 and the autonomic nervous activity evaluation unit 2 evaluate the recorded autonomic nervous index value by performing the operation of replacing the time t in the embodiment of the first invention with the time t ′ on the record. It becomes possible. As described above, the autonomic nervous activity evaluation of the third invention is realized.

This device is effective when evaluating and analyzing autonomic nerve index value data over a long period of time after recording, and when evaluating mental and physical fatigue and stress in everyday situations using a portable data collection device. It is.

FIG. 10 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the fourth invention. This autonomic nervous activity evaluation device differs from the autonomic nervous activity evaluation device of the second invention in that the data recording / reproducing unit 4 is added and the data time is the recording time. Therefore, these different points will be described. The data recording / reproducing unit 4 according to the third invention can be used as the data recording / reproducing unit 4.
Are output to the intra-section reference value calculation unit 3. The in-section reference value calculation unit 3 and the autonomic nervous activity evaluation unit 2 perform the operation of replacing the time t in the embodiment of the second invention with the time t ′ on the record, thereby obtaining the recorded autonomic nerve index value. Evaluation becomes possible. As described above, the autonomic nervous activity evaluation of the fourth invention can be realized.

FIG. 11 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the fifth invention. This apparatus for evaluating autonomic nervous activity is different from the second invention in that the intra-section reference value calculation section 3 in the second invention is replaced with an intra-section average value calculation section 5. The intra-section average value calculation unit 5 takes the time-series data of the autonomic nerve index value as input data, outputs the autonomic nerve index value data as it is, obtains an average value for the autonomic nerve index value within a predetermined time, and calculates the average value. Output as autonomic nervous activity reference value.

The time series data 900 of the autonomic nerve index value is
It is input to the intra-section average value calculation unit 5. The input signal 900 is branched into two systems, one of which is sent to the autonomic nervous activity evaluation unit 2 as it is. The other input signal is a section setting unit 31
Connected to. As the section setting section 31, the section setting section 31 in the intra-section reference value calculation section 3 of the second invention can be used.

Section setting section 3 in the embodiment of the second invention
By the same operation as in 1, the input signal 900 is connected to the maximum / minimum value detection section 32 at the start of the reference value detection, and after a predetermined time has elapsed from the start of the reference value detection, the input signal 900 and the maximum / minimum value detection section 32 Release 32.

The average value V of the autonomic nerve index value for W seconds is

[0075]

(Equation 7)

Is defined as follows. Here, X (t) is the autonomic nerve index value at time t, and Ts is the reference value detection start time.

The intra-section average value calculator 5 calculates the average value V
Is set as the reference value 901, and the autonomic nerve index value 900 and the reference value 901 are output.

The autonomic nervous activity evaluator 2 calculates the autonomic nervous index value X (T) at the current time T and the reference value calculation from the autonomic nervous index value 900 and the reference value 901 output from the intra-section average value calculator 5. From the average value V of the autonomic nerve index value in the section, for example,

[0079]

(Equation 8)

Then, Y (T) is output as the autonomic nervous activity evaluation value 902.

As described above, the apparatus for evaluating autonomic nervous activity according to claim 5 is realized.

When the input data is analog data, the value of V can be obtained by an integrating circuit and a divider incorporating W as a constant. In the case of discrete time-series data Xi, V is

[0083]

(Equation 9)

Is defined as follows. Here, Xi is the i-th autonomic nervous index value after the start of the operation, Ns is i at the start of the reference value detection, and N is the number of autonomic nervous index values input in W seconds.

FIG. 12 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the sixth invention. This autonomic nervous activity evaluation device differs from the autonomic nervous activity evaluation device of the fifth invention in that the data recording / reproducing unit 4 is added and the data time is the recording time. Therefore, these different points will be described. The data recording / reproducing unit 4 according to the third invention can be used as the data recording / reproducing unit 4.
The autonomous nerve index value 911 output during playback is input to the intra-section average value calculation unit 5. The in-section average value calculation unit 5 and the autonomic nervous activity evaluation unit 2 perform the operation in which the time t in the embodiment of the fifth invention is replaced with the time t ′ on the record to obtain the recorded autonomic nerve index value. Evaluation becomes possible. As described above, the autonomic nervous activity evaluation device of the sixth invention can be realized.

FIG. 13 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the seventh aspect of the present invention. This autonomic nervous activity evaluation device is different from the second invention in that the intra-section reference value calculation unit 3 in the second invention is replaced with an evaluation criterion calculation unit 6. The evaluation criterion calculation unit 6 takes the time series data of the autonomic nerve index value as input data, outputs the autonomic nerve index value data as it is, obtains a frequency distribution for the autonomic nerve index value within a predetermined time, and determines the frequency in a predetermined step. Is output as the autonomic nerve activity criterion.

The time series data 900 of the autonomic nerve index value is input to the evaluation criterion calculation unit 6. The input signal 900 is branched into two systems, one of which is sent to the autonomic nervous activity evaluation unit 2 as it is. The other input signal is connected to the section setting unit 31. The setting of the evaluation section in the evaluation criterion calculation unit 6 is as follows.
This can be realized by using the section setting unit 31 in the intra-section reference value calculation unit 3 of the second invention. Autonomic nerve index value data Xi (i = 1, 2, 2) for W seconds passed through the section setting unit 31
, N) can be obtained as follows.

A section boundary value Bj (j = 1, 2,..., M−1) for dividing the autonomic nerve index value into m stages is set in advance. The autonomic nervous index data Xi is sequentially input, and Bk-1
If ≤ Xi ≤ Bk, the value of the frequency distribution value fk is increased by one. By performing the same procedure for all Xi (i = 1, 2,..., N), the frequency distribution fk (k = 1,
2,..., M).

When calculating the autonomic nerve evaluation value as it is from the obtained frequency distribution fk, Bj is used as the evaluation standard 903 and sent to the autonomic nerve evaluation unit 2.

When the autonomic nervous index values Xi in a specific range are to be evaluated in detail, f
k needs to be used as it is, and in a range of values other than the above, it is necessary to perform evaluation by setting m stages to h stages by grouping successive sections. For example, the median value of Xi is i = m
In the case of id, in order to evaluate in detail as far away from Xmid, the new frequency distribution is gu (u = 1, 2,...).
·, H), for example,

[0091]

(Equation 10)

As described above, the frequency distribution value is calculated. Here, R is a constant and a natural number. According to this example, as the distance from the section including the median Xmid increases, the section width of the frequency distribution becomes narrower.

In this way, the section boundary value Du (u = 1, 2,..., H−1) of the new frequency distribution gu is used as the evaluation criterion 903 and the autonomic nervous activity evaluation section 2 together with the autonomic nerve index value 900. Send to

The autonomic nervous activity evaluation section 2 receives the autonomic nervous index value Xi and the evaluation criterion Bj or Du output from the evaluation criterion calculation section 6 and calculates the autonomic nervous activity reference value. For example, Xi is compared with Du in order from u = 1, and Du ≦
The value of u when Xi ≦ Du + 1 is output as the autonomic nerve activity evaluation value 902.

As described above, the autonomic nervous activity evaluation apparatus according to the seventh aspect of the present invention is realized. This autonomic nervous activity evaluation device is limited to the case where the autonomic nervous index value is obtained as discretized data, but obtains an evaluation value in consideration of how easily the input autonomic nervous index value appears. Can be. Such an evaluation value is sensitive to the autonomic nervous index value of the individual deviating from the normal value or the normal range, and is given to the worker when the mental and physical condition during work deviates from the normal value or the normal range. By taking measures such as issuing a warning or temporarily stopping the operation of the system used for the work, it is possible to effectively use the system for self-prevention due to human error.

FIG. 14 shows a basic configuration of an embodiment of the autonomic nervous activity evaluating apparatus according to the eighth aspect of the present invention. This autonomic nervous activity evaluation device differs from the autonomic nervous activity evaluation device of the seventh invention in that the data recording / reproducing unit 4 is added and the data time is the recording time. Therefore, these different points will be described. The data recording / reproducing unit 4 according to the third invention can be used as the data recording / reproducing unit 4.
Is output to the evaluation criterion calculation unit 6 when the reproduction is performed. The evaluation criterion calculating unit 6 and the autonomic nervous activity evaluating unit 2 operate the i of the autonomic nervous index value data Xi in the embodiment of the seventh invention as indicating the order in the recording, thereby recording the recorded autonomic nervous index. The value can be evaluated based on the frequency distribution. As described above, the autonomic nervous activity evaluation device according to the eighth invention can be realized.

FIG. 15 shows a basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the ninth invention. This autonomic nervous activity evaluation device differs from the autonomic nervous activity evaluation device of the first invention in that the reference value calculation unit 1 is replaced with a one-sided reference value calculation unit 7. The one-sided reference value calculation unit 7 receives the time series data of the autonomic nerve index value as input data, outputs the autonomic nerve index value data as it is, obtains the latest maximum value or minimum value of the autonomic nerve index value, and calculates them. Output as autonomic nervous activity reference value.

FIG. 16 shows the internal configuration of the one-sided reference value calculation section 7.

The one-sided reference value calculation unit 7 takes the time series data 900 of the autonomic nerve index value as an input signal. Input signal 900
Is divided into two systems, one of which is sent to the autonomic nervous activity evaluation unit 2 as it is. The other input signal is connected to the limit value detector 12. The limit value detector 12 detects a maximum value Xmax (T) or a minimum value Xmin (T) for the autonomic nerve index value from the start of the operation of the apparatus to the current time.
They are,

[0100]

[Equation 11]

Is defined as follows. Here, X (t) is the autonomic nerve index value at time t, and T is the current time. The limit value calculation unit 1 sets Xmax (T) or Xmin (T) as the reference value 901 and sends it to the autonomic nervous activity evaluation unit 2.

The autonomic nervous activity evaluator 2 includes the autonomic nervous index value 900 and the reference value 90 received from the reference value calculator 1.
1, that is, the autonomic nerve index value X at the current time T
(T), latest maximum value Xmax (T) or minimum value Xmin
From (T), for example,

[0103]

(Equation 12)

Then, Y (T) is output as the autonomic nervous activity evaluation value 902.

The evaluation value Y of the autonomic nerve activity in these examples
(T) is a value indicating how far the autonomic nervous index value of one individual at the current time T is from the lower or upper limit of the obtained data. The larger Y (T) is, the farther from the lower limit or upper limit of the autonomic nervous index value of one individual, and it is desired to evaluate the autonomic nervous activity based on when the autonomic nervous system tension is very high or very low. In this case, the evaluation value is effective. The autonomic nervous activity evaluation device according to the ninth aspect of the present invention performs simpler processing than the autonomic nervous activity evaluation device of the first aspect of the present invention, and is effective when more simple and high-speed processing is desired.

FIG. 17 shows the basic configuration of an embodiment of the autonomic nervous activity evaluation apparatus according to the tenth aspect of the present invention. This autonomic nervous activity evaluation device includes an evaluation criterion storage unit 8 instead of the criterion value calculation unit 1.
And the method for calculating the autonomic nervous activity evaluation value 902 in the autonomic nervous activity evaluation unit 2 is different from the autonomic nervous activity evaluation device of the first invention. Therefore, a method of calculating the autonomic nervous activity evaluation value in the evaluation criterion storage unit 8 and the autonomic nervous activity evaluation unit 2 will be described below.

The evaluation criterion storage unit 8 stores an autonomic nerve index value or a range of values as a reference in advance. For example, [heart rate, 50, 8] as [item, lower limit, upper limit]
0] is stored in a memory, a magnetic storage medium, or the like for the required number of items.

The autonomic nervous activity evaluator 2 takes time series data of an autonomic nerve index value or recorded time series data of an autonomic nerve index value as an input signal. Also, the evaluation criterion storage unit 8
Sends a storage data read signal 200 to the storage data 2
01 is received.

From the input signal 900 and the stored data 201, for example,

[0110]

(Equation 13)

Is calculated. Where T is the current time and X
(T) is the autonomic nerve index value at the current time T, Vl and V
h is the lower limit and upper limit of the input autonomic nerve index described in the storage data 201 as [item, Vl, Vh].

When the calculated Y (T) is 1, X (T)
Is in the normal range, and 0 indicates out of the normal range. This Y (T) is output as the autonomic nerve activity evaluation value 902. Autonomic nerve activity evaluation value 902 obtained here
If a general normal value or a normal range is stored in the evaluation criterion storage unit 8, this indicates whether the autonomic nerve index value of the individual is normal. When the normal value or the normal range of the individual is stored in the evaluation criterion storage unit 8, it indicates whether or not the individual is the normal value for each individual. For example, it is possible to determine whether or not hypertension is determined by the former method, and to determine whether or not each individual is within their normal blood pressure range by the latter method.

FIG. 18 shows a basic configuration of one embodiment of the autonomic nervous activity evaluation apparatus according to the eleventh invention.

The autonomic nervous activity evaluation apparatus presents a test stimulus and outputs a stimulus presentation signal before and after the stimulus is presented. The autonomic nervous index value time series data is used as input data. A reaction amount calculation unit 10 that outputs the index value data as it is, receives a stimulus presentation signal output by the test stimulus presentation unit 9, and calculates a reaction amount of the autonomic nervous system from the autonomic nervous index value when the stimulus presentation signal is received; An autonomic nervous activity evaluation unit 2 outputs an autonomic nervous activity evaluation value from the autonomic nervous index value data output by the reaction amount calculation unit 10 and the autonomic nervous system reaction amount.

The test stimulus presentation section 9 presents sensory stimuli such as visual stimuli, auditory stimuli, and tactile stimuli. Not only a single stimulus but also a stimulus combining audio-visual and tactile sensations, presentation of a mental load such as a calculation task, and administration of a drug in a clinic. For example, a CRT monitor or a flash is used to present a visual stimulus, and a speaker or headphones are used to present an auditory stimulus. In the case of clinical drug administration, a prescribed amount of drug is administered by inserting an injection needle connected by a tube from a drug vial into a patient's vein and controlling the operation of a roller pump combined with the tube.

The test stimulus presenting section 9 outputs the stimulus presentation α
The stimulus presentation signal 202 is sent to the reaction amount calculation unit 10 later and two seconds later.

The reaction amount calculation unit 10 receives the time series data of the autonomic nerve index values before and after the test stimulus presentation by the test stimulus presentation unit 9 as input data, outputs the autonomic nerve index value data as it is, and outputs the autonomic nerve index value. Calculate the reaction that appeared in. As the autonomic nerve index value before the test stimulus is presented, a value when the stimulus presentation signal 202 output by the test stimulus presenting unit 9 is received is used.

When the stimulus presentation time is t = S, for example,

[0119]

[Equation 14]

Is calculated as the reaction amount. However, X (S
+ Α) and X (S−β) are t = S + after stimulus presentation, respectively.
α, an autonomic nerve index value at t = S−β before stimulus presentation, and a stimulus presentation signal 2 output from the test stimulus presentation unit 9
02 is the autonomic nervous index value when the response amount calculation unit 10 receives the value 02.

The autonomic nervous activity evaluator 2 receives R (S + α) and X (S + α) output from the response criterion calculator,
For example,

[0122]

(Equation 15)

Is output as an autonomic nervous activity evaluation value 902. Here, r1 and r2 are constants serving as boundaries for determination, and are incorporated in the autonomic nervous activity evaluation unit 2 in advance.

In this example, the autonomic nerve evaluation value Y (S +
α) is an evaluation of the activity of the autonomic nervous system in three stages from the amount of response of the autonomic nervous index to a stimulus. If 1, the response is too small, 2 is normal, 3 is overreaction, etc. For example, it is a value for evaluating the fatigue state of the autonomic nervous system. A persistent state such as fatigue tends to reflect the activity of the autonomic nervous system in response to a stimulus. This is an effective evaluation value when it is difficult to evaluate autonomic nervous activity only from the autonomic nerve index value or its change.

[0125]

According to the present invention, it becomes possible to evaluate autonomic nervous activity according to individual differences and to evaluate daily autonomic nervous activity for healthy individuals. Furthermore, real-time autonomic nervous activity evaluation is realized, and the burden on the subject and the examiner is reduced. In addition, by applying the present invention to a human interface that presents information while adapting to the activity state of the individual's autonomic nervous system, it is possible to evaluate changes in mental and physical conditions during work and issue instructions and warnings to workers for rest. An information device that emits light can be realized. For example, it is possible to evaluate the autonomic nervous system activity during VDT work and driving a car in real time, instruct a break or give a warning to fall asleep, a human interface effective for maintaining health and preventing accidents, etc. Information equipment becomes feasible.

[Brief description of the drawings]

FIG. 1 is a basic configuration diagram of an embodiment of an autonomic nervous activity evaluation device according to the first invention.

FIG. 2 is a diagram showing signal processing in a reference value calculation unit 1 in one embodiment of the autonomic nervous activity evaluation device of the first invention.

FIG. 3 is a diagram showing an operation of an autonomic nervous activity evaluation unit in one embodiment of the autonomic nervous activity evaluation device of the first invention.

FIG. 4 is an example in which the position of an input signal branch is changed in the basic configuration of one embodiment of the autonomic nervous activity evaluation device of the first invention.

FIG. 5 is a basic configuration diagram of an embodiment of the autonomic nervous activity evaluation device according to the second invention.

FIG. 6 is a diagram showing an internal configuration of an intra-section reference value calculation unit 3 in one embodiment of the autonomic nervous activity evaluation device of the second invention.

FIG. 7 is a diagram showing an operation of a section setting unit 31 in one embodiment of the autonomic nervous activity evaluation device of the second invention.

FIG. 8 is a diagram showing an internal configuration of an intra-section reference value calculation unit 3 in one embodiment of the autonomic nervous activity evaluation device of the second invention.

FIG. 9 is a basic configuration diagram of an embodiment of the autonomic nervous activity evaluation device according to the third invention.

FIG. 10 is a basic configuration diagram of an embodiment of an autonomic nervous activity evaluation device according to a fourth invention.

FIG. 11 is a diagram showing a basic configuration of an embodiment of an autonomic nervous activity evaluation apparatus according to the fifth invention.

FIG. 12 is a basic configuration diagram of an embodiment of the autonomic nervous activity evaluation device according to the sixth invention.

FIG. 13 is a basic configuration diagram of an embodiment of the autonomic nervous activity evaluation device according to the seventh invention.

FIG. 14 is a basic configuration diagram of an embodiment of an autonomic nervous activity evaluation device according to the eighth invention.

FIG. 15 is a diagram showing a basic configuration of an embodiment of an autonomic nervous activity evaluation device according to the ninth invention.

FIG. 16 is a diagram showing an internal configuration of a reference value calculation unit in an embodiment of the autonomic nervous activity evaluation apparatus according to the ninth invention.

FIG. 17 is a basic configuration diagram of an embodiment of the autonomic nervous activity evaluation device according to the tenth invention.

FIG. 18 is a diagram showing a basic configuration of an embodiment of an autonomic nervous activity evaluation device according to the eleventh invention.

[Explanation of symbols]

1 Reference value calculation unit 2 Autonomic nervous activity evaluation unit 3 In-section reference value calculation unit 4 Data recording / reproducing unit 5 In-section average value calculation unit 6 Evaluation reference calculation unit 7 One-sided reference value calculation unit 8 Evaluation reference recording unit 9 Test stimulus presentation Unit 10 reaction amount calculation unit 11 maximum value minimum value detection unit 12 limit value detection unit 31 section setting unit 32 maximum value minimum value detection unit 33 data storage type maximum value minimum value detection unit 200 evaluation reference read signal 201 evaluation reference data 202 stimulation Presentation signal 900 Autonomic nerve index value or time series data of autonomic index value 901 Reference value 902 Autonomic nerve activity evaluation value 3903 Evaluation standard 911 Time series data of autonomic nerve index value or autonomic nerve index value reproduced from recording

Claims (9)

(57) [Claims] 1. An apparatus for evaluating autonomic nervous activity of a living body, wherein time series data of an autonomic nervous index value is used as input data, the autonomic nervous index value data is output as it is, and the latest maximum value of the autonomic nervous index value and A reference value calculation unit that calculates minimum values and outputs them as autonomic nervous activity reference values; and, based on the autonomic nervous index value data and the autonomic nervous activity reference values output by the reference value calculation unit, calculates the autonomic nervous system activity in real time. An autonomic nervous activity evaluation device, comprising: an autonomic nervous activity evaluation unit that outputs an autonomic nervous activity evaluation value in step (a). 2. An apparatus for evaluating autonomic nervous activity of a living body, wherein time series data of an autonomic nervous index value is used as input data, and the autonomic nervous index value data is output as it is. Value and minimum value,
An intra-segment reference value calculation unit that outputs them as autonomic nervous activity reference values, and an autonomic nervous system activity level based on the autonomic nervous index value data and the autonomic nervous activity reference values output by the intra-segment reference value calculation unit. An autonomic nervous activity evaluation device, comprising: an autonomic nervous activity evaluation unit that outputs an autonomic nervous activity evaluation value in step (a). 3. An apparatus for evaluating autonomic nervous activity of a living body, comprising: a data recording / reproducing unit which records all time-series data of an input autonomic nerve index value, and reproduces and outputs the data at the time of evaluation; Using the time series data of the autonomic index value output by the as input data, outputting the autonomic index value data as it is, obtaining the maximum value and the minimum value of the autonomic index value, and outputting them as the autonomic nerve activity reference value. A reference value calculation unit, an autonomic nervous activity evaluation unit that evaluates the autonomic nervous system activity from the autonomic nervous index value data and the autonomic nervous activity reference value output by the reference value calculation unit, and outputs an autonomic nervous activity evaluation value, An autonomic nervous activity evaluation device characterized by having: 4. An apparatus for evaluating autonomic nervous activity of a living body, comprising: a data recording / reproducing unit which records all time-series data of an input autonomic nerve index value and reproduces and outputs the data at the time of evaluation; With the time series data of the autonomic nerve index value output by the as input data, the autonomic nerve index value data is output as it is, the maximum value and the minimum value are obtained for the autonomic nerve index value within a predetermined time, and these are calculated based on the autonomic nerve activity standard. An intra-section reference value calculation unit that outputs a value, an autonomic nervous activity evaluation value by evaluating the autonomic nervous system activity from the autonomic nerve index value data and the autonomic nerve activity reference value output by the intra-section reference value calculation unit. An autonomic nervous activity evaluation unit, which outputs an autonomic nervous activity evaluation unit. 5. An apparatus for evaluating autonomic nervous activity of a living body.
And record all the time series data of the input autonomic nerve index value
A data recording / reproducing unit that reproduces and outputs the data at the time of evaluation; and a time system of the autonomic nerve index value output by the data recording / reproducing unit.
Column data as input data and autonomic nerve index value data as
Output as is, and the autonomic nerve index value within a predetermined time
Average value, and use it as the autonomic nerve activity reference value
An intra-section average value calculation section, and an autonomic nerve index value data output by the intra-section average value calculation section.
The autonomic nervous system activity based on the
Autonomic nervous activity evaluation unit that outputs autonomous nervous activity evaluation values
And an autonomic nervous activity evaluation device, comprising: 6. An apparatus for evaluating autonomic nervous activity of a living body.
Time-series data of the autonomic nerve index value as input data,
Nerve index data and outputs remains fully a predetermined time
Frequency distribution for the autonomic nerve index values in the
Outputs the boundary value divided into fixed stages as the autonomic nerve activity standard
Evaluation reference value calculation unit, and autonomic nerve index value data output by the evaluation reference value calculation unit
And the autonomic nervous activity standard
Autonomic nerve activity that evaluates by time and outputs autonomic nerve activity evaluation value
An autonomic nervous activity evaluation device , comprising: a dynamic evaluation unit . 7. An apparatus for evaluating autonomic nervous activity of a living body.
And record all the time series data of the input autonomic nerve index value
A data recording / reproducing unit that reproduces and outputs the data at the time of evaluation; and a time system of the autonomic nerve index value output by the data recording / reproducing unit.
Column data as input data and autonomic nerve index value data as
Output as is, and the autonomic nerve index value within a predetermined time
Boundary for calculating frequency distribution and dividing frequency into predetermined stages
Evaluation criterion value calculator that outputs values as autonomic nervous activity criteria
And autonomic nerve index value data output by the evaluation reference value calculation unit
And the autonomic nervous activity standard to assess the activity of the autonomic nervous system.
Autonomic nervous activity evaluation unit that outputs autonomous nervous activity evaluation values
And an autonomic nervous activity evaluation device, comprising: 8. An apparatus for evaluating autonomic nervous activity of a living body.
Time-series data of the autonomic nerve index value as input data,
The nerve index value data is output as it is,
Find the latest maximum or minimum value of the index values and calculate them automatically.
A reference value calculation unit that outputs as a rhythmic nerve activity reference value, and autonomic nerve index value data output by the reference value calculation unit;
Autonomic nervous system activity in real time from autonomic nervous activity reference values
Autonomic nerve activity evaluation that evaluates and outputs autonomic nerve activity evaluation values
Autonomic nerve activity evaluation apparatus characterized by comprising: a part, the. 9. An apparatus for evaluating autonomic nervous activity of a living body.
Present the test stimulus and output a stimulus presentation signal before and after the stimulus presentation.
The test stimulus presenting unit to be powered and the time series data of
The nerve index value data is output as it is,
Receiving the stimulus presentation signal output by the stimulus presentation unit,
Of the autonomic nervous system from the autonomic nervous index at the time of signal reception
Outgoing reaction amount calculation unit, and autonomic nerve index value data output by the reaction amount calculation unit and
Outputs autonomic nervous activity evaluation value from autonomic nervous system response
An autonomic nervous activity evaluation device , comprising: an autonomic nervous reaction evaluation unit .