JP2943958B2 - Powder sprayer for nasal cavity - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a nasal powder sprayer for spraying a powdered drug into the nasal cavity.

[0002]

2. Description of the Related Art Generally, a powder sprayer for a nasal cavity is provided with a powder (drug) storage chamber, a pump, and an injection nozzle. The powder in the fixed amount storage chamber is injected by a pump, and the powder is injected into the nasal cavity by the injection nozzle. It is configured to be able to spray.

[0003] In this nasal powder sprayer, it is desirable to spray a predetermined amount of the medicine to be sprayed accurately. Therefore, the conventional nasal powder sprayer includes a powder storage device provided between a pump and an injection nozzle. The chamber was filled with a fixed amount of powder and supplied to the user in a container in which the tip of the injection nozzle was hermetically sealed. In other words, a disposable (disposable) type sprayer which removes the sealed portion at the nozzle tip of the container at the time of use and sprays the container, and then discards the entire container has been proposed and put into practical use.

[0004]

The above-mentioned disposable type sprayer has an advantage that it can spray a metered amount accurately in advance, but since it is a single use disposable system, a large number (about several tens) of the disposable type sprayer is used. Containers must be kept on hand, which is inconvenient for storage. Further, it is not preferable from the viewpoint of resource and environmental protection to dispose of the container only by spraying a small amount of the medicine once.

SUMMARY OF THE INVENTION In view of the foregoing, it is an object of the present invention to provide a powder sprayer for a nasal cavity that can be used repeatedly after replacing a drug cartridge and that can spray a fixed amount of the drug.

[0006]

According to the present invention, there is provided a powder sprayer for a nasal cavity according to the present invention, comprising a base having a powder cartridge and an injection nozzle, a rotor closely contacting the base, and a rotor closely contacting the rotor. A powder metering storage chamber comprising a venting means and a pump communicating with the venting means, and wherein the rotor can be positioned at a filling portion of the cartridge and a pressurizing portion of the injection nozzle, respectively. By rotating the rotor, a fixed amount of powder can be stored and set in the injection unit.

Further, the rotor is configured to be manually rotatable from the outside so that the powder fixed amount storage chamber can be positioned at a desired portion with a simple configuration. A helicoid groove is provided on the outer peripheral surface of the rotor so as to be rotatable at a predetermined angle, and a cam pin engaged with the helicoid groove is provided on an inner surface of a cap attachable to the base. , The powder quantitative storage chamber is automatically positioned at a predetermined position.

[0008] Further, the ventilation means corresponding to the filling portion includes:
The cartridge is provided with a two-way valve that vents so that the cartridge is free at the time of rising and a small amount thereafter, and the venting means corresponding to the pressurizing part is provided in the ejection direction with respect to the ejection nozzle. In addition to a one-way valve that can only vent the air, the powder is filled while being vibrated to perform precise quantification, and a backflow from the injection nozzle side is prevented to prevent contamination.

[0009]

When the cap of the powder sprayer for nasal cavity of the present application is removed, the rotor is rotated by a predetermined angle as the helicoid groove on the outer peripheral surface of the rotor engages and slides on the cam pin on the inner surface of the cap, and the unfilled powder fixed amount is stored. The chambers are moved from the respective standby positions to the filling section, and the filled powder quantitative storage chambers are moved to the pressurizing section.

When the pump is pressed, in the filling section,
First, the powder is pushed up in a columnar shape by the air flowing into the cartridge by the pressure of the pump, and immediately thereafter, the powder drops sharply due to the synergistic action of the suction force (by the restoring force of the pump) and the gravity. For this reason, the columnar powder is compressed by the impact force at the time of falling, and is densely filled in the fixed amount storage chamber.

On the other hand, in the pressurizing section, when the pump is pressed, the pressurized air flows freely into the fixed quantity storage chamber in which the powder is stored, and the powder passes through the injection nozzle together with the pressurized air, and the powder at the tip of the nozzle. It is sprayed into the nasal cavity through the opening.

Next, when the cap is attached, the helicoid groove on the outer peripheral surface of the rotor engages with the cam pin on the inner surface of the cap, and the rotor is again rotated by a predetermined angle as it slides. The unfilled powder fixed quantity storage chamber is moved to the standby position of the filling unit, and the unfilled powder quantitative storage chamber is moved to the standby position of the filling unit. At this time, since the upper surface of the powder quantitative storage chamber is worn off by the lower surface of the base, the columnar powder in the cartridge is cut into a fixed length, and is accurately stored in the powder quantitative storage chamber. When the rotation of the rotor is performed by manual rotation, the positioning of the powder fixed amount storage chamber is confirmed by a click feeling at the time of stoppage of the rotation and by a naked eye through the base.

[0013]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below with reference to an embodiment based on the attached drawings. FIG. 1 is a cross-sectional view showing the overall configuration of the powder sprayer for nasal cavity of the present application, FIG. 2A is an explanatory view of a two-way throttle valve corresponding to a filling section, and FIG. 2B is an illustration of a one-way valve corresponding to a pressurizing section. 3A is a sectional view of the cap, FIG. 3B is a sectional view of the rotor, and FIG. 3C is a sectional view of a helicoid groove provided on the outer peripheral surface of the rotor.

In FIG. 1, reference numeral 1 denotes a base, and the base 1 comprises a cup-shaped cylinder having a circular top plate 1a and a side plate 1b.
A cartridge mounting portion 2 and a spray nozzle mounting portion 4 are provided on the upper surface of the top plate 1a. The cartridge mounting portion 2 includes:
A cartridge 3 containing the powder F is mounted, and an injection nozzle 5 is fixed to the nozzle mounting portion 4. The base 1
May be made of a transparent or semi-transparent member so that the powder quantitative storage chamber 10 provided in the rotor described later can be checked silently.

The cartridge mounting portion 2 and the injection nozzle mounting portion 4 are formed on the circular top plate 1a of the base 1 at an angle equal to or equal to an integer multiple of an equal angle θ of a powder quantitative storage chamber 10 described later (for example, (Eg, 60 degrees, 90 degrees, 180 degrees, and 120 degrees). In this embodiment, they are 180 degrees from each other.

The cartridge 3 is formed of a stick-shaped cylindrical body, and contains therein a powder quantitative storage chamber 1 described later.
About 10 times the volume of 0 (powder or granule drug) F is filled. Further, the injection nozzle 5 is provided with an injection opening 5b for nasal injection at the distal end formed into a spherical shape.

Reference numeral 6 denotes a rotor, which is rotatable about an axis J, and whose upper surface is disposed in close contact with the lower surface of the top plate 1a of the base 1. The rotor 6 may be made of a transparent or translucent material, similarly to the base 1, and may be configured so that the inside of the powder fixed amount storage chamber 10 can be seen through from the outside.

Numeral 7 is a ventilation means. The ventilation means 7 is arranged closely to the rotor 6 and faces the filling portion 3a facing the powder drop opening of the cartridge mounting portion 2 and the injection nozzle mounting portion 4. Each has a pressurizing section 5a. A two-way valve 71 is provided below the filling portion 3a and can be ventilated both when pressurized and when suctioned.

Here, the two-way valve 71 is provided in a cylindrical air passage A1 with a disc film B slightly smaller in diameter than the air passage A1.
1 and the projections T1 on the upper and lower surfaces of the ventilation path A1.
Is provided. Therefore, the film B1
Is located on the upper surface or the lower surface, a small gap corresponding to the height of the projection T1 is formed between the ventilation path A1 and the film B1, so that the air flow is restricted, It will not be done.

That is, when the pump 8 is depressed and contracted, pressurized air is supplied from the pump 8 to the cartridge 3 at the rise thereof.
It is configured so that a small amount of air flows in after that (after the film B1 is positioned on the upper surface). Similarly, when the pump 8 is restored to the original shape and sucked, the pump 8 rises. In some cases, air is freely discharged from the cartridge 3 to the pump 8 side, and then a small amount flows after the film B1 is positioned on the lower surface. For this reason, at the same time as the pump 8 is pressed, the columnar powder F in the cartridge 3 jumps upward, and the pressing of the pump 8 is stopped and expanded, and at the same time, the columnar powder F drops rapidly. . Thus, the columnar powder F is compressed by the impact force at the time of dropping, and is densely filled in the powder fixed amount storage chamber 10.

On the other hand, a one-way valve 72 is provided below the pressurizing section 5a, which can only vent when pressurized. That is,
The one-way valve 72 has a ventilation passage A2 inside the cylindrical ventilation passage A2.
The disk film B2 having a slightly smaller diameter is inserted, and the projection T2 is provided only on the upper surface of the ventilation path A2. Here, the protrusion T2 is a protrusion T of the two-way valve 71.
1, so that even when the film B2 is positioned on the upper surface, the air flow can flow upward without being throttled. Then, the powder F in the fixed amount storage chamber 10 located immediately above the pressurizing portion 5a can be sprayed into the nasal cavity from the opening 5b at the nozzle tip. When the film B2 is located on the lower surface, the airway of the ventilation path A2 is completely blocked, so that the ejection opening 5b
The air does not flow backward from the side to the pressurizing section 5a side.

The fixed volume storage chamber 10 is equally spaced from the rotor 6 at an appropriate angle θ. Under the cartridge mounting portion 2, a cylindrical chamber whose upper surface can communicate with the cartridge 3 and whose lower surface can communicate with the filling portion 3a, respectively. It is configured. That is, the powder F in the cartridge 3 is vibrated and sucked by the action of the two-way valve 71 so that the fixed amount storage chamber 10 can be densely filled. A ventilation filter (sintering ceramics or the like) 11 is provided at the bottom of the fixed amount storage chamber 10 so as to shield the powder F and allow only the air flow to pass therethrough.

The fixed volume storage chamber 10 is formed by a cylindrical chamber below the injection nozzle mounting portion 4, the upper surface of which can communicate with the injection nozzle 5 and the lower surface thereof can communicate with the pressurizing portion 5 a. By the pressure of the pressure portion 5a, the powder F in the fixed amount storage chamber can be ejected to the ejection nozzle 5 together with the compressed air. The fixed volume storage chamber 10 is equally arranged so as to rotate by a predetermined angle with the rotation of the rotor 6, moves from the filling section 3a to the pressurizing section 5a, and fills the powder F filled in the filling section 3a with In addition to allowing the pressurizing section 5a to eject gas, the pressurizing section 5a moves from the pressurizing section 5a to the filling section 3a.
a into the fixed amount storage chamber 10 which has been evacuated and emptied in FIG.
To refill the powder F.

For example, the equal distribution angle θ of the fixed quantity storage chamber 10
If θ = 180 degrees, the fixed quantity storage chamber 10 already filled in the filling section 3a is
When the rotor 6 rotates by 180 degrees, the pressing section 5
a to be sprayed. In addition, if the equal distribution angle θ of the fixed quantity storage chamber 10 is θ = 90 degrees as in the present embodiment, the fixed quantity storage chamber 10 already filled in the filling unit 3a is
Once it is rotated 90 degrees, it stands by (at this time, the previous filled fixed amount storage chamber 10 is supplied for injection by the pressurizing unit), and when it rotates further 90 degrees, it moves to the pressurizing unit 5a. hand,
It will be provided for spraying.

Next, the rotating means of the rotor 6 will be described. As described above, the powder sprayer for a nasal cavity according to the present application causes the powder fixed amount storage chamber 10 to be set in each mode of filling → standby → spout → standby → filling by rotating the rotor 6 by the equal arrangement angle θ. It can be transported. in this case,
Various mechanisms can be considered as a mechanism for rotating the rotor 6, but as a means for automatically rotating, a form in which a cam groove is provided on a side surface of the rotor 6 as illustrated in FIGS.

1 and 3, on the side of the rotor 6,
A helicoid groove 13 capable of rotating the rotor 6 by 45 degrees is provided continuously in the order of forward path, return path, forward path,..., And a cam pin 21 engageable with the helicoid groove 13 is provided on the inner surface of the cap 20. Is erected. Further, the rotor 6 is configured to be rotatable only in one direction by the one-way clutch 12. Further, the cap 20
The notch 1c of the base 1 (the helicoid groove 13
And three guide ribs 22 for engaging the cap 20 with respect to the base 1 in a straight line with respect to the base 1 at an equal angle θ (only one guide rib 22 may be provided). .

Therefore, the cam pin 21 is connected to the helicoid groove 13.
When the cap 20 is pushed down, the cam pin 2
While 1 moves along the outward path of the helicoid groove 13 and reaches the lowermost end, the rotor 6 is at 45 degrees (half of the equal distribution angle θ).
It is configured to rotate only. When the cap 20 attached to the base 1 is pulled out, the cam pin 21 located at the lowermost position moves along the return path of the helicoid groove 13, and further rotates the rotor 6 by 45 degrees. That is, the rotor 6 is configured to be able to automatically rotate by 90 degrees (= equal distribution angle θ) by the mounting and removing operations of the cap 20.

Incidentally, as the simplest form, the rotor 6 may be configured to be manually rotated from the outside. That is,
An opening may be provided at an appropriate position on the side surface of the base 1 to partially expose the outer peripheral surface of the rotor 6 so that a fingertip can be inserted and rotated. Also in this case, it is desirable that the rotor 6 be configured to be rotatable only in one direction by the one-way clutch, and to be stopped with a click feeling at each equal distribution angle θ. Further, the rotor 6 may be formed of a transparent member so that the position of the powder fixed amount storage chamber 10 can be checked silently.

The pump 8 is formed of a bag made of a resilient member. When the pump 8 is pressed, the internal air is pressurized and sent to the filling section 3a and the pressurizing section 5a.
By the elastic deformation force, suction can be performed in reverse. Here, as described above, although the air in the cartridge 3 can flow slightly backward from the filling section 3a, the pressurizing section 5a
Pump 8 cannot expand to its original shape because backflow from is blocked by one-way valve 72. So, pump 8
A small gap 81 communicating with the outside air
When the pressure is released, air flows in through the minute gap 81, and the pump 8 can be restored to the original shape.

In the above embodiment, the cap 2 of the base 1
0, the cam pin 21 on the inner surface of the cap 20 engages and slides along the return path of the helicoid groove 13 and the rotor 6
Is rotated 45 degrees. As a result, the filled powder fixed quantity storage chamber 10 that has been waiting 45 degrees before the pressurizing unit 5a is
Moves to the pressurizing section 5a, and the empty (spouted) powder quantitative storage chamber 10, which has been waiting at 45 degrees before the filling section 3a, is positioned at the filling section 3a.

When the pump 8 is pressed, first, in the filling portion 3a having the valve 71, the disk film B1 in the ventilation path A1 moves upward and comes into contact with the projection T1 to form a minute gap. The compressed air flowing into the gap between the projection T1 and the film B1 flows freely only at the time of rising, and a large amount, and a small amount afterwards, passes through the ventilation filter 11 and reaches a fixed amount storage chamber 10 located immediately above the filling portion 3a. Flows into the interior. At this time, the powder F in the cartridge 3 jumps up in a column shape at the beginning (at the time of free inflow), falls vigorously, collides with the fixed amount storage chamber 10, is compressed, and is densely filled in the fixed amount storage chamber. . Then, the rotor 6 closely contacting the base 1
When is rotated, the upper surface of the fixed amount storage chamber 10 is worn away, so that the amount of the stored powder F is accurately determined.

When the pump 8 is pressed, in the pressurizing portion 5a having the valve 72, the disk film B2 in the air passage A2 moves upward and comes into contact with the projection T2. From the gap between the projection T2 and the film B2, the gas flows through the ventilation filter 11 into the fixed amount storage chamber 10 located immediately above the pressurizing section 5a. The powder F in the fixed amount storage chamber 10 is transferred to the injection nozzle 5 together with the inflowing pressurized air, and further sprayed into the nasal cavity from the opening 5b at the nozzle tip.

Next, when the cap 20 is mounted on the base 1, the cam pin 21 engaged along the outward path of the helicoid groove 13 of the rotor 6 moves straight by the action of the guide rib 22, so that the rotor 6 rotates 45 degrees. And the filling part 3a
The fixed amount storage chamber 10 filled with the powder F stops at a position where neither the upper nor lower surface communicates with the outside air. Furthermore, cap 2
When 0 is pulled out, as described above, the filled powder fixed amount storage chamber 10 that has been waiting before the pressurizing unit 5a moves to the pressurizing unit 5a, and the next spray can be performed.

The above-described series of filling / spraying operations can be continued until the powder F in the cartridge 3 is exhausted (usually 10 times or more). You.

[0035]

As described above, the powder sprayer for nasal cavity of the present invention comprises a powder cartridge, a base having a spray nozzle,
A rotor that is in close contact with the base, ventilation means that is in close contact with the rotor, and a pump that communicates with the ventilation means, wherein the rotor has a filling unit for the contents of the powder cartridge,
And a pressurizing section of the injection nozzle, which is provided with a powder quantity storage chamber which can be positioned, and which is provided with the ventilation means.
The two-way valve is provided on the side corresponding to the filling section,
One-way valve that can vent only in the jet direction on the side corresponding to the part
It is characterized by having
Just operate the pump to
Precise quantification while shaking the filling of these powders.
Backflow from the injection nozzle side can be effectively prevented.

Further, a helicoid groove capable of rotating at a predetermined angle is provided on an outer peripheral surface of the rotor, and a cam pin engaging with the helicoid groove is provided on an inner surface of a cap mountable on the base. In this case, the powder fixed amount storage chamber can be moved to a predetermined position according to the attachment and detachment of the cap.

In addition, the ventilation means corresponding to the filling portion includes:
The cartridge is provided with a two-way valve that vents so that the cartridge is free at the time of rising and a small amount thereafter, and the venting means corresponding to the pressurizing part is provided in the ejection direction with respect to the ejection nozzle. By providing a one-way valve that can only vent to the powder, the powder can be moved up and down in a columnar shape and densely packed, so that the powder can be accurately stored in the powder quantitative storage chamber.

If the rotor is manually rotatable from the outside, the powder fixed amount storage chamber can be positioned with a simple structure. As a result, an excellent effect of being able to provide a nasal powder sprayer that can spray a fixed amount accurately and that can be used repeatedly by exchanging a cartridge is provided.

[0039]

[Brief description of the drawings]

FIG. 1 is a cross-sectional view showing the overall configuration of a powder sprayer for nasal cavity of the present application.

FIG. 2 is an explanatory view showing a valve structure of a filling section and a pressurizing section.

FIG. 3A is a sectional view of a cap. (B) It is sectional drawing of a rotor which shows arrangement | positioning of a powder fixed quantity storage room. (C) is a development view showing a helicoid groove on a rotor side surface.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Substrate 2 Cartridge attachment part 3 Cartridge 4 Injection nozzle attachment part 5 Injection nozzle 6 Rotor 7 Ventilation means 8 Pump 3a Filling part 5a Pressurization part 10 Powder fixed amount storage chamber 11 Ventilation filter 12 One-way clutch 13 Helicoid groove 20 Cap 21 Cam pin 22 Guide rib 71 Two-way valve (throttle valve) 72 One-way valve T1, T2 Projection A1, A2 Ventilation path B1, B2 Disc film F Powder

Claims (2)

(57) [Claims] 1. A substrate having a powder cartridge and an injection nozzle, a rotor in close contact with the substrate, ventilation means in close contact with the rotor, and a pump communicating with the ventilation means, wherein the rotor comprises : filling part of the contents of the powder cartridge, and the pressure portion of the injection nozzle, with each comprising a quantitative powder storage chamber positionable, said vent
Of the means, a two-way valve is provided on the side corresponding to the filling section,
The side corresponding to the pressurizing section can be ventilated only in the ejection direction.
A powder sprayer for nasal cavity, comprising a one-way valve . 2. A helicoid groove for enabling rotation at a predetermined angle is provided on an outer peripheral surface of the rotor, and a cam pin engaging with the helicoid groove is provided on an inner surface of a cap mountable on the base. The powder sprayer for nasal cavity according to claim 1, wherein: