JP2815457B2 - Organic calcium bath liquid - Google Patents

Description

The present invention relates to a novel organic calcium which is effective for treating various diseases such as coldness, neuralgia, pain of old wounds, stiff shoulders, or for maintaining beautiful skin and improving the warm bath effect. It relates to a bath liquid.

Conventional technology Until now, inorganic substances such as sulfur, sodium chloride, sodium bicarbonate, borax, sodium iodide, sodium hydrogen phosphate, ammonium chloride, iron sulfate, menthol, camphor, orange peel, cinnamon skin, salicylic acid, olive oil, Many artificial hot spring baths containing an organic substance such as an enzyme as a component are known. In addition, a composition containing a surfactant or a chelate compound to enhance its therapeutic effect, warm bath effect, or promote penetration into the skin has been proposed (Japanese Patent Publication No. Sho 31).
-3699, JP-B-53-5382).

However, anions contained in conventional artificial hot spring bath salts and natural hot springs are mainly inorganic ions such as bicarbonate ion (HCO ₃ ⁻ ), chloride ion (Cl ⁻ ), and sulfate ion (SO ₄ ²⁻ ). Therefore, it has a strong effect on the human body, is liable to damage body cells, inflammation of the skin, etc., and causes side effects such as hot water fatigue due to interaction with various kinds of coexisting metal ions. The disadvantage is that depending on the concentration, it is rather harmful to the human body.

Problems to be Solved by the Invention The present invention overcomes the drawbacks of natural hot springs and conventional artificial hot spring bath salts, and provides a bath liquid that acts gently on the human body and has a high warm bath effect. It was made for the purpose.

Means for Solving the Problems The present inventors have conducted various studies on the relationship between dissolved components contained in hot springs and their effects over the years, and as a result, it has been found that the causes of various obstacles in hot springs are mainly due to the appropriate amount in the hot springs. Can be caused by inorganic anions or alkali ions in excess of the above, and thus can be converted to organic carboxylate ions or other cations and the final concentration adjusted to the equivalent concentration of isotonic solution. They found that they could be removed and that naturally occurring corals and shells could be a suitable source of cations in this case, and based on these findings led to the present invention.

That is, the present invention dissolves a coral powder or a shell powder in an organic carboxylic acid and, if necessary, adds at least one selected from sodium chloride and potassium chloride, and shows a pH of 2.5 to 6.0 with water. It is intended to provide an organic calcium bath solution diluted to an isotonic solution concentration.

In the present invention, it is necessary to use coral powder or shell powder as a calcium source. Since all of these powders are derived from the secretion of the animal itself, the cation composition therein does not cause any harm to the human body.

There are no particular restrictions on the type of coral and shell, and any type can be used. Coral corals, oysters, scallops, and the like are preferred in that they have a high content of active ingredients and abundant supply.

Further, the organic carboxylic acid used in the present invention is a monobasic acid,
Any of polybasic acids may be used, and acetic acid, citric acid, succinic acid, tartaric acid, oxalic acid, ascorbic acid, lactic acid, malic acid and the like can be used, but citric acid is particularly preferred in that it is colorless and odorless.

These organic carboxylic acids are used as an aqueous solution having a concentration capable of completely dissolving coral powder or shell powder. This concentration varies depending on the type of organic carboxylic acid and the type of powder to be dissolved, but is usually in the range of 5% or more and the saturation concentration or less.

In order to prepare the organic calcium bath solution of the present invention, coral powder or shell powder is added to an aqueous solution of an organic carboxylic acid having an appropriate concentration, and sufficiently dissolved by stirring. At this time, if necessary, the dissolution can be promoted by heating. The solution thus obtained is filtered off, if any insoluble solids are present,
If desired, sodium chloride or potassium chloride is added, and the mixture is diluted with water until the concentration of isotonic solution, that is, the concentration showing the same osmotic pressure as that of body fluid. At this time, the pH of the diluted aqueous solution is adjusted to be in the range of 2.5 to 6.0. Thus, by diluting to the isotonic solution concentration, it is possible to prevent adverse effects on somatic cells due to imbalance in osmotic pressure.

An organic acid salt such as sodium citrate, a fragrance, a coloring agent, a surfactant, and the like can be further added to the prepared bath liquid as desired.

Next, an example of a system suitable for using the bath liquid of the present invention as a warm bath will be described with reference to the accompanying drawings.

The figure is a system diagram showing one example of a bath facility system for using the bath liquid of the present invention, in which a coral powder or a shell powder is mixed and dissolved in an organic carboxylic acid aqueous solution having a predetermined concentration in a dissolution tank 1. The solution is prepared by the pump 2, and the solution is sent to the storage tank 4 via the filter 3 by the pump 2 and stored. next,
In the mixing tank 5, the organic calcium solution from the storage tank 4 and the sodium chloride or potassium chloride aqueous solution from the storage tank 6 are mixed, and if necessary, water is introduced from a pipe 7 to prepare a bath solution having an isotonic solution concentration. Prepare and adjust the pH to 2.5-6.0
Adjust within the range. The bath liquid thus prepared is heated to a required temperature and then supplied to a bathtub 9 in a bathroom by a pump 8 as needed.

At this time, the humidity in the bathroom varies depending on the season, weather, the influence of the atmosphere on the building structure, the movement of air when entering and exiting, etc., even if the bath temperature is constant. It is necessary to keep the humidity and temperature in the bathroom as constant as possible to achieve the full effect.
It is advantageous to constantly circulate fresh dry air maintained at about 45 to 55 ° C.

By doing so, sweating is promoted together with a refreshing feeling, and the warm bath effect is further promoted.

Effect of the Invention The organic calcium bath solution of the present invention acts more gently on the human body than natural hot springs and conventional artificial hot spring baths, so that it does not cause skin damage or adverse effects on body cells, and is excellent. Can give a warm bath effect.

In addition, the effect can be further enhanced by using in combination with a specific bathroom facility system.

Examples Next, the present invention will be described in more detail with reference to examples.

Example 1 50 g of citric acid was added to hot water 1 at 60 ° C. and completely dissolved, and then 12 g of pure white coral powder (produced in Bali, Indonesia) was added and stirred for 30 minutes. At this time, the coral powder was dissolved while generating carbon dioxide.

Next, the insoluble matter was removed by filtration, and 200 ml of hot water at 45 ° C. was added to dilute to prepare an organic calcium bath solution. Calcium concentration in this bath solution is 22ppm, citric acid concentration is 243pp
m, and the pH of the bath solution was 4.2.

Example 2 An organic calcium bath solution was prepared in the same manner as in Example 1, except that 10 g of scallop shell powder was used instead of coral powder.

The bath solution thus obtained has a calcium concentration of 18 pp
m, the citric acid concentration was 238 ppm and the pH was 4.1.

Example 3 An organic calcium bath liquid was prepared on a practical scale using the bathroom facility system shown in the drawing.

That is, a 0.5 m ³ volume dissolution tank 1 equipped with a stirrer
Put 60 ° C hot water 130 into the mixture and stir with citric acid 14k
g was added and completely dissolved.

Next, while stirring, 5 kg of coral powder was gradually added and dissolved, and the mixture was further stirred for 30 minutes. The solution thus obtained was filtered through a filter 3 to remove insoluble components, and then stored in a 0.3 m ³ storage tank 4.

Separately, in a 0.3 m ³ storage tank 6, hot water 100 of 60 ° C., 4 kg of sodium citrate dihydrate and 2 kg of calcium chloride were mixed and completely dissolved by stirring.

Next, hot water 440 at 450 ° C. is put into the mixing tank 5 having a capacity of 1 m ³ , and the solution 35 from the storage tank 4 and the solution 25 from the storage tank 6 are introduced into the mixing tank 5 with stirring, and transferred to the bath 8 after 5 minutes. did. This operation was repeated four times to prepare about 2000 bath solutions. Ca concentration of bath liquid in bathtub is 1058ppm, Na concentration is 470ppm, K concentration is 516ppm, citric acid concentration is 7450ppm, C
l concentration was 458 ppm. The pH was 4.8.

Example 4 Hot water at 45 ° C. was placed in a 0.3 m ³ dissolution tank equipped with a stirrer.
After adding 00, 9 kg of citric acid was added with stirring to completely dissolve. Next, 2 kg of coral powder was gradually added and dissolved while stirring, and the solution was filtered through a filter to remove insoluble components, thereby preparing about 200 organic calcium bath liquid. The calcium concentration in this bath solution was 3980 ppm, the citric acid concentration was about 40,000 ppm, and the total molar concentration of calcium and citric acid was 0.311 mol /. The pH is
3.4.

Example 5 In Example 1, 12 g of coral powder was dissolved by using 50 g of malic acid instead of citric acid, insolubles were removed from this solution, and 200 parts of hot water was added to prepare a solution for an organic calcium bath. The calcium concentration in this bath is 25 ppm,
The malic acid concentration was 222 ppm, and the pH of the bath solution was 4.2.

Reference Example An auxiliary bath made by Arjo was filled with bath liquid 180, and the bathing effect was examined over three days using six healthy young men as subjects.

That is, two hours after the meal, the subject kept quiet for about 30 minutes was placed naked in a bathtub, warm-bathed for 7 minutes at a water level such that the collarbone submerged in a half-recumbent position, and then placed in a resting state for 15 minutes. . The subject was bathed twice, and the second time was after 24 hours.

 The bathing conditions at this time were as follows.

Indoor air pressure 954 ± 15mb Temperature 71 ± 5% Room temperature 35 ± 1.7 ℃ Bath temperature 38.5 ± 0.7 ℃ Measurements are made by Nihon Kohden Bedside Monitor, Lifescope 11, OMP-7201K, Nippon Electric Sanei Aerobics, Processor 391- B, Heart rate, oxygen intake, minute ventilation, respiratory rate, blood pressure, deep body temperature and buoyancy were measured using a Terumo electronic sphygmomanometer manufactured by Terumo Corporation and a Thermo Finer Core Balance.

The results obtained by using the organic calcium prepared in Example 3 as a sample are shown below.

1) Heart rate; increased at the same time as taking a bath and increased at a maximum of 51%, but quickly recovered to resting level after taking a bath.

2) Oxygen intake, minute ventilation, respiratory rate: During bathing, the level at rest was almost maintained, and no particular change was observed.

3) Blood pressure: About 10 mmHg for systolic blood pressure and about 20 mmHg for diastolic blood pressure after bathing
Decreased, and the value was maintained during bathing. After bathing, the diastolic blood pressure returned to the value before bathing, but the systolic blood pressure was increased by about 10 mmHg in some subjects.

4) Deep body temperature; increased immediately after taking a bath, the rate of increase was high in the order of the back of the foot, the forehead, and the back of the hand. Even after 20 minutes from bathing, there was sweating and did not return to the value before bathing. This is clearly different from the usual bath without organic calcium,
It shows that it has the effect of keeping warmth.

5) Feeling of buoyancy: The buoyancy and the sense of relaxation were remarkable compared to the case of a normal bath, and the upper part of the body tended to be exposed on the water surface.

[Brief description of the drawings]

The drawings are system diagrams showing one example of a bath equipment system suitable for using the bath liquid of the present invention, in which 1 is a dissolution tank, 3 is a filter, 4, 6 is a storage tank, and 5 is a storage tank. The mixing tank 8 is a bathtub.

──────────────────────────────────────────────────続 き Continued on the front page (58) Field surveyed (Int.Cl. ⁶ , DB name) A61K 7/50 A61K 35/00 A61K 35/56

Claims (2)

(57) [Claims] 1. An organic calcium bath solution obtained by dissolving coral powder or shell powder in an organic carboxylic acid and then diluting with water to an isotonic solution having a pH of 2.5 to 6. 2. The bath liquid according to claim 1, further comprising at least one selected from sodium chloride and potassium chloride.