JP2555144B2 - Detection fluid for carious parts of teeth - Google Patents

Description

TECHNICAL FIELD The present invention relates to a detection liquid for a carious part of a tooth in the field of dentistry.

(Prior Art) In treating a diseased tooth, it is necessary to completely remove a carious portion, but on the other hand, it is not desirable to unnecessarily cut and remove a healthy portion. Conventionally, the distinction between a carious part and a healthy part in the affected tooth has utilized the difference in hardness of each part or the difference in hue due to natural discoloration of the carious part. However, none of these differences show a definite boundary between each part,
The decision is largely due to the experience of the dentist. For this reason, it is preferable to excessively cut a healthy portion rather than leave the carious portion uncut, and thus excessive cutting has generally been performed. However, recently, it has been recognized that it is important to preserve particularly healthy parts as much as possible, to minimize the sacrifice of the affected tooth, and particularly to avoid exposing the pulp as much as possible in the part close to the pulp. There is a demand for a detection liquid that accurately detects only the carious part to be removed. As such a detection liquid, a detection liquid for a dental caries portion of a dye such as Acid Red dissolved in an organic solvent, water, or a mixture thereof is described in JP-B-56-48490, and among them, Acid Red is used. It has been reported that a liquid dissolved in a mixed solvent of propylene glycol and water is effective for detecting carious parts of teeth (Soyama et al., Journal of Conservative Medicine of Japan, Vol. 22, No. 2, page 37 ( 1979)).

(Problems to be Solved by the Present Invention) In order to save clinical time, it is desired to remove carious portions of teeth as quickly as possible. On the other hand, the above-mentioned detection liquid for carious parts can be used without any problem in terms of distinguishability of carious parts, but if the carious parts are thick, dyeing with the detection liquid and removal of colored parts must be repeated. . For this reason, similar to the conventional method, the carious part is naturally colored and the hardness difference between it and the sound part is roughly removed, and then the carious part is left uncut by using the above caries detecting solution. The presence or absence of is checked. In such a case, a healthy portion may be deleted when the rough deletion is performed, and the healthy tooth structure may not be saved to the maximum extent. For this reason, there is a demand for a detection solution for carious parts that has a large penetration depth into the carious parts and that does not stain sound dental substance.

(Means for Solving the Problem) The present inventor pays attention to this point, and has a greater penetration depth to the carious portion than the conventional detection liquid for the carious portion and does not stain healthy dentin. As a result of extensive studies on the detection liquid of the portion, the present invention has been achieved.

In other words, as a result of examining the penetration depth of the detection liquid of various compositions into the carious part, by using dimethylsulfoxide as the organic solvent, it penetrates deeper into the carious part than when using conventional propylene glycol. I found what to do. Furthermore, it has been found that the addition effect of an organic acid further enhances the penetration effect to the carious part.

The detection liquid for the carious part of the tooth of the present invention is a solution in which ascid red is dissolved as a pigment in dimethyl sulfoxide or a mixed liquid of dimethyl sulfoxide and water, and an organic acid may be further added.

The acid red used in the dental caries detection solution of the present invention is 9- (3,4,5,6-tetrachloro-ortho-carboxyphenyl) -6-hydroxy-2,4,5,7-tetrabromo-. It is the potassium salt of 3-isoxanthone.

The organic acid used in the detection liquid of the dental caries part of the present invention is carboxylic acid, ascorbic acid or a mixture thereof, and as the carboxylic acid, formic acid, acetic acid, lactic acid, butyric acid,
Pyruvate, nonanoic acid, hexanoic acid, heptanoic acid, methacrylic acid, acrylic acid, benzoic acid, aminobenzoic acid, salicylic acid, aminosalicylic acid, oxalic acid, succinic acid, tartaric acid, glutaric acid, fumaric acid, maleic acid, malonic acid,
Examples thereof include ethylenediaminetetraacetic acid (EDTA) and ketoglutaric acid. These carboxylic acids may be used alone or as a mixture of two or more kinds. Of these, citric acid is preferred.

The concentration of Acid Red in the detection liquid is preferably 0.1 to 5.0% by weight. If the concentration is lower than 0.1% by weight,
When the carious part is not sufficiently colored and the concentration is higher than 5% by weight, the coloring reaches even the healthy part, which makes identification difficult. More preferably, it is 1-2% by weight.

When a mixed solution of dimethyl sulfoxide and water is used as a solvent, the concentration of dimethyl sulfoxide in the mixed solution may be 5% by weight or more.

The organic acid may be present in an amount of 60% by weight or less with respect to dimethyl sulfoxide or a mixed liquid of dimethyl sulfoxide and water.

The detection solution of the present invention may be prepared by adding a desired amount of Acid Red to a mixture of dimethyl sulfoxide or water with dimethyl sulfoxide and stirring and dissolving at room temperature or under heating. Alternatively, dimethylsulfoxide, water or a mixed solution thereof in which more than the desired amount of Acid Red is previously dissolved, is diluted with dimethylsulfoxide and / or water at the time of use to obtain a desired concentration. Good.

To apply the detection liquid of the present invention to a carious part of a patient's tooth, the detection liquid is put in a container having an elongated nozzle, and a small amount of the detection liquid is dropped from the tip of the nozzle onto the carious part.
It is carried out by washing the carious part with water after ~ 10 seconds.
By this operation, only the carious part is clearly dyed, and the healthy dentin is hardly dyed. Therefore, only the carious part can be accurately detected. The detection liquid of the present invention is extremely effective therapeutically.

 Hereinafter, the present invention will be further described with reference to examples.

(Examples 1 and 2 and Comparative Examples 1 and 2) Acid red was mixed with dimethylsulfoxide at room temperature and stirred to prepare the detection solutions of Examples 1 and 2 in Table 1, and to remove the dentin of the extracted tooth. It was examined whether or not the carious part and the healthy part can be distinctly dyed (dyeability). further,
Using 5 teeth for each example, the operation of dyeing the carious part and carefully deleting the red dyed part with a low-speed round bar was repeated, and the average amount of deletion (average dyeing depth) was determined once.

Further, the detection liquids of Comparative Examples 1 and 2 were also prepared, and
The same test as in 2 was performed, and the results are also shown.

The dental caries detecting portion of the present invention is capable of dyeing carious portions and healthy portions of dentin separately, and has an average amount of deletion larger than that of the comparative example, which is superior to the conventional dental caries detecting portion. There is.

(Example 3 and comparative column 3) Acid red was mixed and stirred at room temperature in a mixed solution of dimethyl sulfoxide, citric acid and water to prepare a detection solution shown in Example 3 of Table 2. Using this, the dyeing property was examined in the same manner as in Example 1, and the average amount of deletion and the number of times for 10 extracted teeth were determined.

Also, the detection liquid of Comparative Example 3 was prepared, the same test was conducted, and the results are also shown.

The caries detecting part of the tooth of the present invention can stain the carious part and the healthy part of dentin, and the average amount of deletion is larger than that of the comparative example, and the average number of times of deletion is small. As described above, the detection liquid of the present invention is superior to the conventional detection liquids as a detection liquid for the carious part of the tooth.

(Effects of the Invention) According to the present invention, carious dentin and healthy dentin of a tooth can be easily dyed separately, and the depth of penetration into the carious part is large, and an improved detection liquid can be provided. .

Claims (1)

(57) [Claims] 1. A detection solution for a carious part of a tooth, which is obtained by dissolving Acid Red in dimethyl sulfoxide or a mixed solution of dimethyl sulfoxide and water.