JP2025515505A - 超高分子量ポリマーおよびその製造方法と使用方法 - Google Patents

超高分子量ポリマーおよびその製造方法と使用方法 Download PDF

Info

Publication number
JP2025515505A
JP2025515505A JP2024563727A JP2024563727A JP2025515505A JP 2025515505 A JP2025515505 A JP 2025515505A JP 2024563727 A JP2024563727 A JP 2024563727A JP 2024563727 A JP2024563727 A JP 2024563727A JP 2025515505 A JP2025515505 A JP 2025515505A
Authority
JP
Japan
Prior art keywords
water
soluble polymer
unit
group
mucin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024563727A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025515505A5 (https=
Inventor
リー ギャレット デイビッドソン,カレン
ロット,メーガン
オルソン,レベッカ
アイバン ペドロ,ディエゴ
グレゴリー ソーヤー,ウォレス
エス サマリン,ブレント
Original Assignee
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド filed Critical ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
Publication of JP2025515505A publication Critical patent/JP2025515505A/ja
Publication of JP2025515505A5 publication Critical patent/JP2025515505A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F120/00Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F120/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F120/52Amides or imides
    • C08F120/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F120/00Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F120/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F120/52Amides or imides
    • C08F120/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F120/56Acrylamide; Methacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/32Polymerisation in water-in-oil emulsions
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/38Polymerisation using regulators, e.g. chain terminating agents, e.g. telomerisation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/46Polymerisation initiated by wave energy or particle radiation
    • C08F2/48Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/46Polymerisation initiated by wave energy or particle radiation
    • C08F2/48Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
    • C08F2/50Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light with sensitising agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/34Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56Acrylamide; Methacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24Homopolymers or copolymers of amides or imides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24Homopolymers or copolymers of amides or imides
    • C08L33/26Homopolymers or copolymers of acrylamide or methacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2438/00Living radical polymerisation
    • C08F2438/03Use of a di- or tri-thiocarbonylthio compound, e.g. di- or tri-thioester, di- or tri-thiocarbamate, or a xanthate as chain transfer agent, e.g . Reversible Addition Fragmentation chain Transfer [RAFT] or Macromolecular Design via Interchange of Xanthates [MADIX]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerisation Methods In General (AREA)
  • Graft Or Block Polymers (AREA)
JP2024563727A 2022-04-29 2023-04-28 超高分子量ポリマーおよびその製造方法と使用方法 Pending JP2025515505A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263336733P 2022-04-29 2022-04-29
US63/336,733 2022-04-29
US202263368404P 2022-07-14 2022-07-14
US63/368,404 2022-07-14
PCT/US2023/066335 WO2023212672A2 (en) 2022-04-29 2023-04-28 Ultra-high molecular weight polymers and methods of making and using the same

Publications (2)

Publication Number Publication Date
JP2025515505A true JP2025515505A (ja) 2025-05-15
JP2025515505A5 JP2025515505A5 (https=) 2026-02-09

Family

ID=88519897

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024563727A Pending JP2025515505A (ja) 2022-04-29 2023-04-28 超高分子量ポリマーおよびその製造方法と使用方法

Country Status (11)

Country Link
US (1) US20230357461A1 (https=)
EP (1) EP4514867A2 (https=)
JP (1) JP2025515505A (https=)
KR (1) KR20250033149A (https=)
CN (1) CN119731223A (https=)
AU (1) AU2023262591A1 (https=)
CA (1) CA3251104A1 (https=)
GB (1) GB2633232A (https=)
MX (1) MX2024013370A (https=)
TW (1) TW202402814A (https=)
WO (1) WO2023212672A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3088067B1 (fr) * 2018-11-06 2020-11-06 S N F Sa Procede de synthese de polymeres par polymerisation radicalaire controlee en emulsion inverse
WO2025155868A1 (en) * 2024-01-18 2025-07-24 Univeristy Of Florida Research Foundation, Inc. Polymers and methods making and using polymers
WO2025186703A1 (en) * 2024-03-04 2025-09-12 Alcon Inc. Carbamoylphenylboronic acid-containing acrylic monomers and uses thereof
WO2025250734A1 (en) * 2024-05-29 2025-12-04 University Of Florida Research Foundation, Inc. High molecular weight polymers and methods of making the same
CN119144002B (zh) * 2024-09-20 2025-05-30 扬州工业职业技术学院 一种超支化多支链聚醚破乳剂及其制备方法
CN119381051A (zh) * 2024-12-31 2025-01-28 浙江摩克激光智能装备有限公司 一种ltcc用快速紫外光固化导电银浆及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040151886A1 (en) * 2000-03-06 2004-08-05 Bobsein Barrett Richard Binder composition
US7832856B2 (en) * 2006-12-20 2010-11-16 Bausch & Lomb Incorporated Coatings and solutions for contact lenses
US9993439B2 (en) * 2012-06-20 2018-06-12 University Of Waterloo Mucoadhesive nanoparticle delivery system
US11505634B2 (en) * 2017-12-19 2022-11-22 Spcm Sa Method for producing anionic water-soluble polymer on the basis of bioacrylamide and acrylic acid
CN117999081A (zh) * 2021-08-31 2024-05-07 佛罗里达大学研究基金会公司 超高分子量聚合物及其使用方法

Also Published As

Publication number Publication date
TW202402814A (zh) 2024-01-16
KR20250033149A (ko) 2025-03-07
WO2023212672A3 (en) 2023-12-07
CN119731223A (zh) 2025-03-28
GB2633232A (en) 2025-03-05
WO2023212672A2 (en) 2023-11-02
US20230357461A1 (en) 2023-11-09
MX2024013370A (es) 2025-02-10
GB202415979D0 (en) 2024-12-11
EP4514867A2 (en) 2025-03-05
AU2023262591A1 (en) 2024-11-21
CA3251104A1 (en) 2023-11-02

Similar Documents

Publication Publication Date Title
JP2025515505A (ja) 超高分子量ポリマーおよびその製造方法と使用方法
Olson et al. Inverse miniemulsion photoiniferter polymerization for the synthesis of ultrahigh molecular weight polymers
d'Agosto et al. RAFT‐mediated polymerization‐induced self‐assembly
An 100th anniversary of macromolecular science viewpoint: achieving ultrahigh molecular weights with reversible deactivation radical polymerization
Penfold et al. Emerging trends in polymerization-induced self-assembly
Byard et al. Preparation and cross-linking of all-acrylamide diblock copolymer nano-objects via polymerization-induced self-assembly in aqueous solution
Hill et al. Expanding the scope of RAFT polymerization: recent advances and new horizons
Khan et al. RAFT emulsion polymerization for (multi) block copolymer synthesis: overcoming the constraints of monomer order
Corrigan et al. Copolymers with controlled molecular weight distributions and compositional gradients through flow polymerization
Yeow et al. Polymerization-induced self-assembly using visible light mediated photoinduced electron transfer–reversible addition–fragmentation chain transfer polymerization
Cunningham et al. Poly (glycerol monomethacrylate)–poly (benzyl methacrylate) diblock copolymer nanoparticles via RAFT emulsion polymerization: synthesis, characterization, and interfacial activity
Chaduc et al. RAFT polymerization of methacrylic acid in water
Truong et al. Facile production of nanoaggregates with tuneable morphologies from thermoresponsive P (DEGMA-co-HPMA)
Shahrokhinia et al. PhotoATRP-induced self-assembly (PhotoATR-PISA) enables simplified synthesis of responsive polymer nanoparticles in one-pot
Darabi et al. Nitroxide-mediated polymerization of 2-(diethylamino) ethyl methacrylate (DEAEMA) in water
Quek et al. RAFT Synthesis and aqueous solution behavior of novel pH-and thermo-responsive (co) polymers derived from reactive poly (2-vinyl-4, 4-dimethylazlactone) scaffolds
Gyorgy et al. RAFT dispersion polymerization of methyl methacrylate in mineral oil: High glass transition temperature of the core-forming block constrains the evolution of copolymer morphology
Davidson IV et al. Inverse miniemulsion enables the continuous-flow synthesis of controlled ultra-high molecular weight polymers
McKenzie et al. Highly efficient and versatile formation of biocompatible star polymers in pure water and their stimuli-responsive self-assembly
György et al. Tuning the glass transition temperature of a core-forming block during polymerization-induced self-assembly: statistical copolymerization of lauryl methacrylate with methyl methacrylate provides access to spheres, worms, and vesicles
Fortenberry et al. A perspective on the history and current opportunities of aqueous RAFT polymerization
Yuan et al. Nonspherical nanoparticles with controlled morphologies via seeded surface-initiated single electron transfer radical polymerization in soap-free emulsion
Bowman et al. Controlling morphological transitions of polymeric nanoparticles via doubly responsive block copolymers
Shahrokhinia et al. Chain extensions in PhotoATRP-induced self-assembly (photoATR-PISA): a route to ultrahigh solids concentrations and click nanoparticle networks as adsorbents for water treatment
Li et al. Core-first synthesis and thermoresponsive property of three-, four-, and six-arm star-shaped poly (N, N-diethylacrylamide) s and their block copolymers with poly (N, N-dimethylacrylamide)

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260129

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20260129