JP2025514485A - 酸化ストレスの診断バイオマーカー - Google Patents

酸化ストレスの診断バイオマーカー Download PDF

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Publication number
JP2025514485A
JP2025514485A JP2024564840A JP2024564840A JP2025514485A JP 2025514485 A JP2025514485 A JP 2025514485A JP 2024564840 A JP2024564840 A JP 2024564840A JP 2024564840 A JP2024564840 A JP 2024564840A JP 2025514485 A JP2025514485 A JP 2025514485A
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JP
Japan
Prior art keywords
ptprn2
cells
methylation status
methylation
aging
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Pending
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JP2024564840A
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English (en)
Japanese (ja)
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JP2025514485A5 (https=
Inventor
ベール，フローリアン
ロイ，スキ
ボーランド，ジェニファー
ナガラジャン，サンジャナー
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Evonik Operations GmbH
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Evonik Operations GmbH
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Publication of JP2025514485A publication Critical patent/JP2025514485A/ja
Publication of JP2025514485A5 publication Critical patent/JP2025514485A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2024564840A 2022-05-03 2023-04-21 酸化ストレスの診断バイオマーカー Pending JP2025514485A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22171354.8 2022-05-03
EP22171354 2022-05-03
PCT/EP2023/060484 WO2023213573A1 (en) 2022-05-03 2023-04-21 Diagnostic biomarker for oxidative stress

Publications (2)

Publication Number Publication Date
JP2025514485A true JP2025514485A (ja) 2025-05-02
JP2025514485A5 JP2025514485A5 (https=) 2026-04-28

Family

ID=81580165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024564840A Pending JP2025514485A (ja) 2022-05-03 2023-04-21 酸化ストレスの診断バイオマーカー

Country Status (8)

Country Link
US (1) US20250290141A1 (https=)
EP (1) EP4519458B1 (https=)
JP (1) JP2025514485A (https=)
KR (1) KR20250004022A (https=)
CN (1) CN119137288A (https=)
CA (1) CA3251480A1 (https=)
TW (1) TW202407104A (https=)
WO (1) WO2023213573A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118910283B (zh) * 2024-09-09 2025-03-07 西藏自治区农牧科学院 与藏绵羊抗氧化应激能力相关的snp分子标记及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7658288B2 (en) 2004-11-08 2010-02-09 Applied Biosystems, Llc Bisulfite conversion reagent
US20130283404A1 (en) * 2012-03-30 2013-10-24 The Regents Of The University Of Michigan Epigenetics in autoimmunity

Also Published As

Publication number Publication date
EP4519458A1 (en) 2025-03-12
CA3251480A1 (en) 2023-11-09
WO2023213573A1 (en) 2023-11-09
US20250290141A1 (en) 2025-09-18
KR20250004022A (ko) 2025-01-07
EP4519458B1 (en) 2026-02-25
CN119137288A (zh) 2024-12-13
TW202407104A (zh) 2024-02-16
AU2023266036A1 (en) 2024-12-12

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