JP2025513763A - 口腔内用製剤、透過性密封バッグ、錠剤、方法、及びその使用 - Google Patents

口腔内用製剤、透過性密封バッグ、錠剤、方法、及びその使用 Download PDF

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Publication number
JP2025513763A
JP2025513763A JP2024558188A JP2024558188A JP2025513763A JP 2025513763 A JP2025513763 A JP 2025513763A JP 2024558188 A JP2024558188 A JP 2024558188A JP 2024558188 A JP2024558188 A JP 2024558188A JP 2025513763 A JP2025513763 A JP 2025513763A
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JP
Japan
Prior art keywords
nicotine
chemically bonded
formulation
bonded ceramic
ceramic system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024558188A
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English (en)
Japanese (ja)
Other versions
JP2025513763A5 (https=
Inventor
ハカン エンクヴィスト
イェスパー レーフ
Original Assignee
エンプリキュア アクチエボラゲット（ピーユービーエル）
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2204804.5A external-priority patent/GB2613211B/en
Priority claimed from GBGB2208807.4A external-priority patent/GB202208807D0/en
Application filed by エンプリキュア アクチエボラゲット（ピーユービーエル） filed Critical エンプリキュア アクチエボラゲット（ピーユービーエル）
Publication of JP2025513763A publication Critical patent/JP2025513763A/ja
Publication of JP2025513763A5 publication Critical patent/JP2025513763A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Addiction (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
JP2024558188A 2022-04-01 2023-04-03 口腔内用製剤、透過性密封バッグ、錠剤、方法、及びその使用 Pending JP2025513763A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2204804.5 2022-04-01
GB2204804.5A GB2613211B (en) 2022-04-01 2022-04-01 Alkaline oral formulations
GBGB2208807.4A GB202208807D0 (en) 2022-06-15 2022-06-15 Alkaline intraoral formulations
GB2208807.4 2022-06-15
PCT/EP2023/058713 WO2023187224A1 (en) 2022-04-01 2023-04-03 Alkaline intraoral formulations

Publications (2)

Publication Number Publication Date
JP2025513763A true JP2025513763A (ja) 2025-04-30
JP2025513763A5 JP2025513763A5 (https=) 2026-04-13

Family

ID=86096079

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024558188A Pending JP2025513763A (ja) 2022-04-01 2023-04-03 口腔内用製剤、透過性密封バッグ、錠剤、方法、及びその使用

Country Status (7)

Country Link
US (1) US20250228770A1 (https=)
EP (1) EP4504146B1 (https=)
JP (1) JP2025513763A (https=)
CN (1) CN119136784A (https=)
CA (1) CA3246977A1 (https=)
MX (1) MX2024012083A (https=)
WO (1) WO2023187224A1 (https=)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9848634B2 (en) * 2009-06-30 2017-12-26 Philip Morris Products S.A. Smokeless tobacco product
CN101966165B (zh) * 2009-07-14 2012-06-13 无锡健而乐医药科技有限公司 口腔吸收固体泡腾制剂
SE535587C2 (sv) 2011-03-29 2012-10-02 Chill Of Sweden Ab Produkt innehållande ett fritt nikotinsalt och en ej vattenlöslig påse
CN103284318B (zh) * 2013-06-20 2015-03-11 中国烟草总公司山东省公司 一种舌下烟及其制备方法
WO2015193379A1 (en) * 2014-06-18 2015-12-23 Swedish Match North Europe Ab A tobacco or non-tobacco product comprising magnesium carbonate
CN107259635A (zh) * 2017-06-16 2017-10-20 云南中烟工业有限责任公司 一种烟碱复合盐含化片及其制备方法
GB201714412D0 (en) * 2017-09-07 2017-10-25 Emplicure Ab Evaporation devices containing plant material
WO2019110073A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Solid oral nicotine formulation
CA3085065C (en) * 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
JP2022519542A (ja) * 2019-02-01 2022-03-24 スウィーディッシュ・マッチ・ノース・ヨーロップ・アーベー ｐＨ調整剤を含む経口用ニコチン製品
US20210169123A1 (en) * 2019-12-09 2021-06-10 Nicoventures Trading Limited Pouched products with enhanced flavor stability
GB202105305D0 (en) * 2021-04-14 2021-05-26 Zanoprima Lifesciences Ltd Supported nicotine composition

Also Published As

Publication number Publication date
WO2023187224A1 (en) 2023-10-05
US20250228770A1 (en) 2025-07-17
EP4504146A1 (en) 2025-02-12
MX2024012083A (es) 2025-01-09
EP4504146B1 (en) 2025-12-17
CN119136784A (zh) 2024-12-13
CA3246977A1 (en) 2023-10-05
EP4504146C0 (en) 2025-12-17

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