JP2025511161A5 - - Google Patents

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Publication number
JP2025511161A5
JP2025511161A5 JP2024557983A JP2024557983A JP2025511161A5 JP 2025511161 A5 JP2025511161 A5 JP 2025511161A5 JP 2024557983 A JP2024557983 A JP 2024557983A JP 2024557983 A JP2024557983 A JP 2024557983A JP 2025511161 A5 JP2025511161 A5 JP 2025511161A5
Authority
JP
Japan
Application number
JP2024557983A
Other languages
Japanese (ja)
Other versions
JP2025511161A (ja
JPWO2023194310A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/058693 external-priority patent/WO2023194310A1/en
Publication of JP2025511161A publication Critical patent/JP2025511161A/ja
Publication of JP2025511161A5 publication Critical patent/JP2025511161A5/ja
Publication of JPWO2023194310A5 publication Critical patent/JPWO2023194310A5/ja
Pending legal-status Critical Current

Links

JP2024557983A 2022-04-04 2023-04-03 Kras g12c阻害剤及びtead阻害剤の治療的組合せ Pending JP2025511161A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22305439 2022-04-04
EP22305439.6 2022-04-04
PCT/EP2023/058693 WO2023194310A1 (en) 2022-04-04 2023-04-03 Therapeutic combination of kras g12c inhibitor and tead inhibitor

Publications (3)

Publication Number Publication Date
JP2025511161A JP2025511161A (ja) 2025-04-15
JP2025511161A5 true JP2025511161A5 (https=) 2026-04-10
JPWO2023194310A5 JPWO2023194310A5 (https=) 2026-04-10

Family

ID=81326107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557983A Pending JP2025511161A (ja) 2022-04-04 2023-04-03 Kras g12c阻害剤及びtead阻害剤の治療的組合せ

Country Status (5)

Country Link
US (1) US20250295664A1 (https=)
EP (1) EP4504203A1 (https=)
JP (1) JP2025511161A (https=)
CN (1) CN118973584A (https=)
WO (1) WO2023194310A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210006356A (ko) 2018-04-04 2021-01-18 아비나스 오퍼레이션스, 인코포레이티드 단백질분해 조절제 및 연관된 사용 방법
CN121419983A (zh) 2023-01-26 2026-01-27 阿尔维纳斯运营股份有限公司 基于小脑蛋白的kras降解protac及其相关用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7039489B2 (ja) 2016-05-18 2022-03-22 ミラティ セラピューティクス, インコーポレイテッド Kras g12c阻害剤
WO2018119183A2 (en) 2016-12-22 2018-06-28 Amgen Inc. Kras g12c inhibitors and methods of using the same
EA201992781A1 (ru) 2017-05-22 2020-04-01 Эмджен Инк. Ингибиторы g12c kras и способы их применения
HRP20230377T1 (hr) 2017-11-15 2023-06-23 Mirati Therapeutics, Inc. Inhibitori mutacije kras g12c
WO2019213516A1 (en) 2018-05-04 2019-11-07 Amgen Inc. Kras g12c inhibitors and methods of using the same
WO2020055761A1 (en) * 2018-09-10 2020-03-19 Mirati Therapeutics, Inc. Combination therapies
JP7377679B2 (ja) * 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
TW202128699A (zh) * 2019-11-27 2021-08-01 美商建南德克公司 治療性化合物
US20230140808A1 (en) 2020-04-07 2023-05-04 Sanofi (1 H-Indol-5-YL)Acrylamide Derivatives as Inhibitors of Tead Proteins and the Hippo-YAP1/TAZ Signaling Cascade for the Treatment of Cancer
US11787775B2 (en) * 2020-07-24 2023-10-17 Genentech, Inc. Therapeutic compounds and methods of use
JP7774612B2 (ja) 2020-07-30 2025-11-21 サノフイ アクリルアミド置換インダン化合物およびその治療的使用

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