JP2025510942A - 亜酸化窒素及び５－ｈｔ２ａ受容体作動薬の組み合わせ - Google Patents

亜酸化窒素及び５－ｈｔ２ａ受容体作動薬の組み合わせ Download PDF

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Publication number
JP2025510942A
JP2025510942A JP2024557455A JP2024557455A JP2025510942A JP 2025510942 A JP2025510942 A JP 2025510942A JP 2024557455 A JP2024557455 A JP 2024557455A JP 2024557455 A JP2024557455 A JP 2024557455A JP 2025510942 A JP2025510942 A JP 2025510942A
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Japan
Prior art keywords
substituted
unsubstituted
methyl
indol
amine
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Pending
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JP2024557455A
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Japanese (ja)
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JP2025510942A5 (https=
Inventor
パルフレイマン，マイケル
ニヴォロジキン，アレックス
ジェイ． グリーン，ブレット
ミノ，ロバート
クレア ライヒェルト，エイミー
ビー． ヴァーティ，ジェフリー
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サイビン アイアールエル リミテッド
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Publication of JP2025510942A publication Critical patent/JP2025510942A/ja
Publication of JP2025510942A5 publication Critical patent/JP2025510942A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2024557455A 2022-03-31 2023-03-29 亜酸化窒素及び５－ｈｔ２ａ受容体作動薬の組み合わせ Pending JP2025510942A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263362258P 2022-03-31 2022-03-31
US63/362,258 2022-03-31
PCT/EP2023/058107 WO2023186963A1 (en) 2022-03-31 2023-03-29 Combination of nitrous oxide and 5-ht2a receptor agonists

Publications (2)

Publication Number Publication Date
JP2025510942A true JP2025510942A (ja) 2025-04-15
JP2025510942A5 JP2025510942A5 (https=) 2026-04-06

Family

ID=86007250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557455A Pending JP2025510942A (ja) 2022-03-31 2023-03-29 亜酸化窒素及び５－ｈｔ２ａ受容体作動薬の組み合わせ

Country Status (5)

Country Link
EP (1) EP4499087A1 (https=)
JP (1) JP2025510942A (https=)
AU (1) AU2023242469A1 (https=)
CA (1) CA3247035A1 (https=)
WO (1) WO2023186963A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021328671A1 (en) 2020-08-18 2023-02-16 Cybin Irl Limited Phenethylamine derivatives, compositions, and methods of use
EP4396162A4 (en) 2021-09-03 2025-11-12 Alexander Shulgin Res Institute Inc ASYMMETRIC ALLYL TRYPTAMINES
WO2024108195A1 (en) 2022-11-17 2024-05-23 Remedi, Inc. Combinations of monoamine oxidase inhibitors and serotonin receptor agonists and their therapeutic use
EP4704806A1 (en) * 2023-05-05 2026-03-11 Cybin IRL Limited Injectable pharmaceutical formulations
CN121752545A (zh) * 2023-11-06 2026-03-27 宜昌人福药业有限责任公司 一种n,n-二甲基色胺衍生物及其药物组合物、制备方法和用途
WO2025099725A1 (en) * 2023-11-09 2025-05-15 Hadasit Medical Research Services And Development Ltd. Conjugates and uses thereof

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US5612059A (en) 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
DE4023108C1 (https=) 1990-07-20 1992-02-13 Ems Gmbh, 8520 Moehrendorf, De
US5798119A (en) 1995-06-13 1998-08-25 S. C. Johnson & Son, Inc. Osmotic-delivery devices having vapor-permeable coatings
ID28302A (id) 1999-01-14 2001-05-10 Teijin Ltd Alat untuk mengumpankan suatu bubuk dalam jumlah tertentu
GB0121568D0 (en) 2001-09-06 2001-10-24 Optinose As Nasal delivery device
CN1736502A (zh) 1999-03-03 2006-02-22 奥普蒂诺斯公司 鼻传送装置
GB0114272D0 (en) 2001-06-12 2001-08-01 Optinose As Nasal delivery device
GB0019715D0 (en) 2000-08-10 2000-09-27 Pa Consulting Services Device for delivering physiologically active agent in powdered form
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
WO2003026559A2 (en) 2001-09-28 2003-04-03 Kurve Technology, Inc Nasal nebulizer
GB0207422D0 (en) 2002-03-28 2002-05-08 Optinose As Nasal devices
GB0207817D0 (en) 2002-04-04 2002-05-15 Optinose As Nasal devices
GB0209494D0 (en) 2002-04-25 2002-06-05 Optinose As Nasal devices
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US8826905B2 (en) 2007-06-01 2014-09-09 Ramses Nashed Respiratory face mask and breathing circuit assembly
US20100192947A1 (en) 2009-02-04 2010-08-05 Jeff Mandel Anesthetic delivery system and methods of use
CA2763021C (en) 2010-02-22 2013-03-05 Class 1 Inc. Apparatus, systems and methods for collecting and reclaiming anaesthetic agents and for removing nitrous oxide from exhaust gases
EP2589403B1 (en) 2011-05-31 2016-02-03 Ishikita, Naoyuki Anesthetic inhalation-assisting device
US12377112B2 (en) * 2019-04-17 2025-08-05 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
EP3902541B1 (en) * 2020-06-02 2022-09-14 Small Pharma Ltd Therapeutic compositions comprising deuterated or partially deuterated n,n-dimethyltryptamine compounds
RU199823U1 (ru) 2020-06-10 2020-09-21 Общество С Ограниченной Ответственностью "Центр Передовых Радиационных Медицинских И Биологических Технологий Устройство для лечения бронхолегочных заболеваний

Also Published As

Publication number Publication date
EP4499087A1 (en) 2025-02-05
AU2023242469A1 (en) 2024-09-05
WO2023186963A1 (en) 2023-10-05
CA3247035A1 (en) 2023-10-05

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