JP2025507749A5 - - Google Patents

Info

Publication number
JP2025507749A5
JP2025507749A5 JP2024550753A JP2024550753A JP2025507749A5 JP 2025507749 A5 JP2025507749 A5 JP 2025507749A5 JP 2024550753 A JP2024550753 A JP 2024550753A JP 2024550753 A JP2024550753 A JP 2024550753A JP 2025507749 A5 JP2025507749 A5 JP 2025507749A5
Authority
JP
Japan
Prior art keywords
modified oligonucleotide
nucleic acid
modified
nucleoside
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024550753A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025507749A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/063353 external-priority patent/WO2023164696A2/en
Publication of JP2025507749A publication Critical patent/JP2025507749A/ja
Publication of JP2025507749A5 publication Critical patent/JP2025507749A5/ja
Pending legal-status Critical Current

Links

JP2024550753A 2022-02-28 2023-02-27 プリオン発現のＲＮＡｉ剤 Pending JP2025507749A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263314800P 2022-02-28 2022-02-28
US63/314,800 2022-02-28
PCT/US2023/063353 WO2023164696A2 (en) 2022-02-28 2023-02-27 Rnai agents of prion expression

Publications (2)

Publication Number Publication Date
JP2025507749A JP2025507749A (ja) 2025-03-21
JP2025507749A5 true JP2025507749A5 (cg-RX-API-DMAC7.html) 2026-03-10

Family

ID=87766801

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024550753A Pending JP2025507749A (ja) 2022-02-28 2023-02-27 プリオン発現のＲＮＡｉ剤

Country Status (4)

Country Link
US (1) US20260028623A1 (cg-RX-API-DMAC7.html)
EP (1) EP4486892A2 (cg-RX-API-DMAC7.html)
JP (1) JP2025507749A (cg-RX-API-DMAC7.html)
WO (1) WO2023164696A2 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12281305B2 (en) 2018-11-21 2025-04-22 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing prion expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120225922A1 (en) * 2011-03-04 2012-09-06 Qr Pharma Effective Amounts of (3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo [2,3-b]indol-5-yl Phenylcarbamate and Methods of Treating or Preventing Neurodegeneration
US12281305B2 (en) * 2018-11-21 2025-04-22 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing prion expression

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