JP2025507154A - 眼の状態の治療を目的とした連続投薬レジメン - Google Patents

眼の状態の治療を目的とした連続投薬レジメン Download PDF

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Publication number
JP2025507154A
JP2025507154A JP2024553782A JP2024553782A JP2025507154A JP 2025507154 A JP2025507154 A JP 2025507154A JP 2024553782 A JP2024553782 A JP 2024553782A JP 2024553782 A JP2024553782 A JP 2024553782A JP 2025507154 A JP2025507154 A JP 2025507154A
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JP
Japan
Prior art keywords
drug delivery
day
borolanib
insert
days
Prior art date
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Pending
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JP2024553782A
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English (en)
Japanese (ja)
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JP2025507154A5 (https=
Inventor
サイード サイム，
ダリオ パッジャリーノ，
オーウェン， エヌ． ダラム，
ナンシー ラーカー，
ジェイ， エス． デューカー，
ミッシェル ハワード‐スパークス，
バーゼル カルズーン，
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Eyepoint Pharmaceuticals Inc
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Eyepoint Pharmaceuticals Inc
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Publication date
Application filed by Eyepoint Pharmaceuticals Inc filed Critical Eyepoint Pharmaceuticals Inc
Publication of JP2025507154A publication Critical patent/JP2025507154A/ja
Publication of JP2025507154A5 publication Critical patent/JP2025507154A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024553782A 2022-03-11 2023-03-10 眼の状態の治療を目的とした連続投薬レジメン Pending JP2025507154A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202263318823P 2022-03-11 2022-03-11
US63/318,823 2022-03-11
US202263320984P 2022-03-17 2022-03-17
US63/320,984 2022-03-17
US202263341456P 2022-05-13 2022-05-13
US63/341,456 2022-05-13
US202263390051P 2022-07-18 2022-07-18
US63/390,051 2022-07-18
PCT/US2023/064148 WO2023173093A1 (en) 2022-03-11 2023-03-10 Continuous dosing regimen for treatment of a condition of the eye

Publications (2)

Publication Number Publication Date
JP2025507154A true JP2025507154A (ja) 2025-03-13
JP2025507154A5 JP2025507154A5 (https=) 2026-04-07

Family

ID=85937358

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024553782A Pending JP2025507154A (ja) 2022-03-11 2023-03-10 眼の状態の治療を目的とした連続投薬レジメン

Country Status (9)

Country Link
US (1) US20250186398A1 (https=)
EP (1) EP4489750A1 (https=)
JP (1) JP2025507154A (https=)
KR (1) KR20240156416A (https=)
AU (1) AU2023230976A1 (https=)
CA (1) CA3245209A1 (https=)
IL (1) IL315333A (https=)
TW (1) TW202400143A (https=)
WO (1) WO2023173093A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
AU2021340733A1 (en) * 2020-09-14 2023-05-18 EyePoint Pharmaceuticals, Inc. Bioerodible ocular drug delivery insert and therapeutic method
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2565683T3 (es) 2006-09-15 2016-04-06 Xcovery, Inc. Compuestos inhibidores de quinasa
WO2018059556A1 (zh) 2016-09-29 2018-04-05 贝达药业股份有限公司 激酶抑制剂化合物的多晶型、含其的药物组合物及其制备方法和应用
EP4537830A3 (en) * 2017-06-13 2025-06-11 EyePoint Pharmaceuticals, Inc. Bioerodible drug delivery devices
AU2021340733A1 (en) * 2020-09-14 2023-05-18 EyePoint Pharmaceuticals, Inc. Bioerodible ocular drug delivery insert and therapeutic method

Also Published As

Publication number Publication date
IL315333A (en) 2024-10-01
WO2023173093A1 (en) 2023-09-14
KR20240156416A (ko) 2024-10-29
TW202400143A (zh) 2024-01-01
US20250186398A1 (en) 2025-06-12
CA3245209A1 (en) 2023-09-14
WO2023173093A9 (en) 2023-12-07
EP4489750A1 (en) 2025-01-15
AU2023230976A1 (en) 2024-09-19

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