JP2025507032A5 - - Google Patents
Info
- Publication number
- JP2025507032A5 JP2025507032A5 JP2024552486A JP2024552486A JP2025507032A5 JP 2025507032 A5 JP2025507032 A5 JP 2025507032A5 JP 2024552486 A JP2024552486 A JP 2024552486A JP 2024552486 A JP2024552486 A JP 2024552486A JP 2025507032 A5 JP2025507032 A5 JP 2025507032A5
- Authority
- JP
- Japan
- Prior art keywords
- cell line
- mammalian cell
- endogenous
- asns
- asn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263268857P | 2022-03-04 | 2022-03-04 | |
| US63/268,857 | 2022-03-04 | ||
| PCT/US2023/063672 WO2023168397A1 (en) | 2022-03-04 | 2023-03-03 | Metabolic selection via the asparagine biosynthesis pathway |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507032A JP2025507032A (ja) | 2025-03-13 |
| JP2025507032A5 true JP2025507032A5 (https=) | 2025-11-17 |
Family
ID=86099966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024552486A Pending JP2025507032A (ja) | 2022-03-04 | 2023-03-03 | アスパラギン生合成経路を介した代謝選択 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20260028611A1 (https=) |
| EP (1) | EP4486874A1 (https=) |
| JP (1) | JP2025507032A (https=) |
| KR (1) | KR20240151871A (https=) |
| CN (1) | CN119137265A (https=) |
| CA (1) | CA3244807A1 (https=) |
| WO (1) | WO2023168397A1 (https=) |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4656134A (en) * | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| US5011776A (en) * | 1988-02-11 | 1991-04-30 | The Royal Institution For The Advancement Of Learning (Mcgill University) | Shuttle vector, utilizing the E. coli asparagine synthetase gene, and capable of dominant transfection and amplification in animal cells |
| US5487994A (en) | 1992-04-03 | 1996-01-30 | The Johns Hopkins University | Insertion and deletion mutants of FokI restriction endonuclease |
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5356802A (en) | 1992-04-03 | 1994-10-18 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoites (FokI) restriction endonuclease |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US6242568B1 (en) | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| USRE39229E1 (en) | 1994-08-20 | 2006-08-08 | Gendaq Limited | Binding proteins for recognition of DNA |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US5776746A (en) * | 1996-05-01 | 1998-07-07 | Genitope Corporation | Gene amplification methods |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB2338237B (en) | 1997-02-18 | 2001-02-28 | Actinova Ltd | In vitro peptide or protein expression library |
| GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| ES2341926T3 (es) | 1998-03-02 | 2010-06-29 | Massachusetts Institute Of Technology | Poliproteinas con dedos de cinc que tienen enlazadores mejorados. |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| AU2001263155A1 (en) | 2000-05-16 | 2001-11-26 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US20070134796A1 (en) | 2005-07-26 | 2007-06-14 | Sangamo Biosciences, Inc. | Targeted integration and expression of exogenous nucleic acid sequences |
| WO2020012446A1 (en) * | 2018-07-13 | 2020-01-16 | Enzene Biosciences Limited | Double knock-out cho cell line method of its generation and producing therapeutic proteins therefrom |
-
2023
- 2023-03-03 CA CA3244807A patent/CA3244807A1/en active Pending
- 2023-03-03 US US18/842,333 patent/US20260028611A1/en active Pending
- 2023-03-03 EP EP23718942.8A patent/EP4486874A1/en active Pending
- 2023-03-03 JP JP2024552486A patent/JP2025507032A/ja active Pending
- 2023-03-03 KR KR1020247033152A patent/KR20240151871A/ko active Pending
- 2023-03-03 WO PCT/US2023/063672 patent/WO2023168397A1/en not_active Ceased
- 2023-03-03 CN CN202380038098.7A patent/CN119137265A/zh active Pending
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