JP2025505738A - がんの治療 - Google Patents

がんの治療 Download PDF

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Publication number
JP2025505738A
JP2025505738A JP2024547619A JP2024547619A JP2025505738A JP 2025505738 A JP2025505738 A JP 2025505738A JP 2024547619 A JP2024547619 A JP 2024547619A JP 2024547619 A JP2024547619 A JP 2024547619A JP 2025505738 A JP2025505738 A JP 2025505738A
Authority
JP
Japan
Prior art keywords
lag
protein
derivative
subject
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024547619A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505738A5 (https=
Inventor
トリーベル，フレデリック
Original Assignee
イムテップ エス．アー．エス．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2201803.0A external-priority patent/GB202201803D0/en
Priority claimed from GBGB2218181.2A external-priority patent/GB202218181D0/en
Application filed by イムテップ エス．アー．エス． filed Critical イムテップ エス．アー．エス．
Publication of JP2025505738A publication Critical patent/JP2025505738A/ja
Publication of JP2025505738A5 publication Critical patent/JP2025505738A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2024547619A 2022-02-11 2023-02-10 がんの治療 Pending JP2025505738A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2201803.0 2022-02-11
GBGB2201803.0A GB202201803D0 (en) 2022-02-11 2022-02-11 Treatment of Cancer
GB2218181.2 2022-12-02
GBGB2218181.2A GB202218181D0 (en) 2022-12-02 2022-12-02 Treatment of cancer
PCT/EP2023/053381 WO2023152335A1 (en) 2022-02-11 2023-02-10 Treatment of cancer

Publications (2)

Publication Number Publication Date
JP2025505738A true JP2025505738A (ja) 2025-02-28
JP2025505738A5 JP2025505738A5 (https=) 2026-02-19

Family

ID=85227021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024547619A Pending JP2025505738A (ja) 2022-02-11 2023-02-10 がんの治療

Country Status (9)

Country Link
US (1) US20250368714A1 (https=)
EP (1) EP4475955A1 (https=)
JP (1) JP2025505738A (https=)
KR (1) KR20240149422A (https=)
AU (1) AU2023219133A1 (https=)
CA (1) CA3250299A1 (https=)
IL (1) IL314687A (https=)
MX (1) MX2024009818A (https=)
WO (1) WO2023152335A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025229157A1 (en) * 2024-05-01 2025-11-06 Immutep S.A.S. Combination therapy using lag-3 protein and anti-pd-1 inhibitor with radiotherapy for treating cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2044949A1 (en) 2007-10-05 2009-04-08 Immutep Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
IL298507A (en) * 2020-05-28 2023-01-01 Immutep Sas Treatment of cancer

Also Published As

Publication number Publication date
EP4475955A1 (en) 2024-12-18
IL314687A (en) 2024-10-01
CA3250299A1 (en) 2023-08-17
MX2024009818A (es) 2024-08-19
KR20240149422A (ko) 2024-10-14
AU2023219133A1 (en) 2024-09-05
WO2023152335A1 (en) 2023-08-17
US20250368714A1 (en) 2025-12-04

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