JP2025501865A - 抗light抗体で喘息を治療する方法 - Google Patents

抗light抗体で喘息を治療する方法 Download PDF

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Publication number
JP2025501865A
JP2025501865A JP2024532504A JP2024532504A JP2025501865A JP 2025501865 A JP2025501865 A JP 2025501865A JP 2024532504 A JP2024532504 A JP 2024532504A JP 2024532504 A JP2024532504 A JP 2024532504A JP 2025501865 A JP2025501865 A JP 2025501865A
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JP
Japan
Prior art keywords
light
subject
light antibody
antibody
asthma
Prior art date
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Pending
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JP2024532504A
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English (en)
Japanese (ja)
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JP2025501865A5 (https=
Inventor
ギャリー エー. ニール,
エイチ. ジェフリー ウィルキンス,
シェリダン ジェイ. キャリントン,
Original Assignee
アヴァロ セラピューティクス, インコーポレイテッド
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Application filed by アヴァロ セラピューティクス, インコーポレイテッド filed Critical アヴァロ セラピューティクス, インコーポレイテッド
Publication of JP2025501865A publication Critical patent/JP2025501865A/ja
Publication of JP2025501865A5 publication Critical patent/JP2025501865A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024532504A 2022-01-05 2023-01-04 抗light抗体で喘息を治療する方法 Pending JP2025501865A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263296786P 2022-01-05 2022-01-05
US63/296,786 2022-01-05
US202263396308P 2022-08-09 2022-08-09
US63/396,308 2022-08-09
PCT/US2023/060064 WO2023133389A2 (en) 2022-01-05 2023-01-04 Methods of treating asthma with anti-light antibodies

Publications (2)

Publication Number Publication Date
JP2025501865A true JP2025501865A (ja) 2025-01-24
JP2025501865A5 JP2025501865A5 (https=) 2026-01-15

Family

ID=87074254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024532504A Pending JP2025501865A (ja) 2022-01-05 2023-01-04 抗light抗体で喘息を治療する方法

Country Status (6)

Country Link
US (1) US20250002598A1 (https=)
EP (1) EP4460523A4 (https=)
JP (1) JP2025501865A (https=)
AU (1) AU2023205910A1 (https=)
CA (1) CA3240327A1 (https=)
WO (1) WO2023133389A2 (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007290570C1 (en) * 2006-08-28 2013-08-15 Kyowa Kirin Co., Ltd. Antagonistic human LIGHT-specific human monoclonal antibodies
US20090136427A1 (en) * 2007-09-18 2009-05-28 La Jolla Institute For Allergy And Immunology LIGHT Inhibitors For Asthma, Lung and Airway Inflammation, Respiratory, Interstitial, Pulmonary and Fibrotic Disease Treatment
EP3730188B1 (en) * 2015-08-21 2024-07-31 The Children's Hospital of Philadelphia Compositions and methods for use in combination for the treatment and diagnosis of autoimmune diseases

Also Published As

Publication number Publication date
AU2023205910A1 (en) 2024-06-06
US20250002598A1 (en) 2025-01-02
CA3240327A1 (en) 2023-07-13
EP4460523A4 (en) 2025-12-17
EP4460523A2 (en) 2024-11-13
WO2023133389A2 (en) 2023-07-13
WO2023133389A3 (en) 2023-08-31

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