JP2025500808A - 次世代シーケンシングにおける一次分析 - Google Patents

次世代シーケンシングにおける一次分析 Download PDF

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Publication number
JP2025500808A
JP2025500808A JP2024534498A JP2024534498A JP2025500808A JP 2025500808 A JP2025500808 A JP 2025500808A JP 2024534498 A JP2024534498 A JP 2024534498A JP 2024534498 A JP2024534498 A JP 2024534498A JP 2025500808 A JP2025500808 A JP 2025500808A
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Prior art keywords
sequence
sample index
flow cell
sequencing
cycles
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Pending
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JP2024534498A
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English (en)
Japanese (ja)
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JP2025500808A5 (https=
Inventor
ジョウ，チュンホン
クルグリャック，セミヨン
ガルシア，フランシスコ
グオ，ミンハオ
ワン，ハオセン
ケリー，ライアン
Original Assignee
エレメント バイオサイエンシズ，インコーポレイティド
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Priority claimed from US17/547,602 external-priority patent/US11397870B2/en
Priority claimed from US17/725,065 external-priority patent/US12371743B2/en
Priority claimed from US17/725,042 external-priority patent/US12359193B2/en
Application filed by エレメント バイオサイエンシズ，インコーポレイティド filed Critical エレメント バイオサイエンシズ，インコーポレイティド
Publication of JP2025500808A publication Critical patent/JP2025500808A/ja
Publication of JP2025500808A5 publication Critical patent/JP2025500808A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Signal Processing (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2024534498A 2021-12-10 2022-12-09 次世代シーケンシングにおける一次分析 Pending JP2025500808A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US17/547,602 2021-12-10
US17/547,602 US11397870B2 (en) 2020-08-31 2021-12-10 Single-pass primary analysis
US202263316790P 2022-03-04 2022-03-04
US202263316784P 2022-03-04 2022-03-04
US63/316,784 2022-03-04
US63/316,790 2022-03-04
US17/725,065 US12371743B2 (en) 2022-03-04 2022-04-20 Double-stranded splint adaptors and methods of use
US17/725,042 US12359193B2 (en) 2022-03-04 2022-04-20 Single-stranded splint strands and methods of use
US17/725,042 2022-04-20
US17/725,065 2022-04-20
US202263349421P 2022-06-06 2022-06-06
US63/349,421 2022-06-06
US17/854,042 US11915444B2 (en) 2020-08-31 2022-06-30 Single-pass primary analysis
US17/854,042 2022-06-30
PCT/US2022/052449 WO2023107720A1 (en) 2021-12-10 2022-12-09 Primary analysis in next generation sequencing

Publications (2)

Publication Number Publication Date
JP2025500808A true JP2025500808A (ja) 2025-01-15
JP2025500808A5 JP2025500808A5 (https=) 2025-12-16

Family

ID=86731140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024534498A Pending JP2025500808A (ja) 2021-12-10 2022-12-09 次世代シーケンシングにおける一次分析

Country Status (6)

Country Link
EP (1) EP4445327A4 (https=)
JP (1) JP2025500808A (https=)
KR (1) KR20240162477A (https=)
AU (1) AU2022407176A1 (https=)
CA (1) CA3240445A1 (https=)
WO (1) WO2023107720A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US12391929B2 (en) 2019-05-24 2025-08-19 Element Biosciences, Inc. Polymerase-nucleotide conjugates for sequencing by trapping
AU2022316142A1 (en) 2021-07-21 2024-02-22 Element Biosciences, Inc. Optical systems for nucleic acid sequencing and methods thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8965076B2 (en) * 2010-01-13 2015-02-24 Illumina, Inc. Data processing system and methods
EP3051450A1 (en) * 2015-02-02 2016-08-03 Applied Maths Method of typing nucleic acid or amino acid sequences based on sequence analysis
CN111655855B (zh) * 2017-09-14 2025-09-09 生命明疗法股份有限公司 人治疗靶标及其调节剂
US20190130999A1 (en) * 2017-10-26 2019-05-02 Indigo Ag, Inc. Latent Representations of Phylogeny to Predict Organism Phenotype
US12009060B2 (en) * 2018-12-14 2024-06-11 Merck Sharp & Dohme Llc Identifying biosynthetic gene clusters
EP3924505B1 (en) * 2019-02-12 2025-12-17 10X Genomics, Inc. Methods for processing nucleic acid molecules

Also Published As

Publication number Publication date
CA3240445A1 (en) 2023-06-15
AU2022407176A1 (en) 2024-06-27
WO2023107720A1 (en) 2023-06-15
EP4445327A1 (en) 2024-10-16
KR20240162477A (ko) 2024-11-15
EP4445327A4 (en) 2026-01-14

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