JP2024543158A - 多重特異性リガンド結合分子及びその用途 - Google Patents

多重特異性リガンド結合分子及びその用途 Download PDF

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Publication number
JP2024543158A
JP2024543158A JP2024531308A JP2024531308A JP2024543158A JP 2024543158 A JP2024543158 A JP 2024543158A JP 2024531308 A JP2024531308 A JP 2024531308A JP 2024531308 A JP2024531308 A JP 2024531308A JP 2024543158 A JP2024543158 A JP 2024543158A
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JP
Japan
Prior art keywords
vegf
amino acid
ligand
binding molecule
lfv
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JP2024531308A
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English (en)
Japanese (ja)
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JP2024543158A5 (https=
Inventor
チエン－シン チャン
チンチン イン
Original Assignee
スーチョウ ライト フェリー バイオメッド．カンパニー，リミティド
ホンコン ライト フェリー バイオメッド．リミティド
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Publication of JP2024543158A publication Critical patent/JP2024543158A/ja
Publication of JP2024543158A5 publication Critical patent/JP2024543158A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024531308A 2021-11-24 2021-11-24 多重特異性リガンド結合分子及びその用途 Withdrawn JP2024543158A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2021/132735 WO2023092324A1 (zh) 2021-11-24 2021-11-24 多特异性配体结合分子及其应用

Publications (2)

Publication Number Publication Date
JP2024543158A true JP2024543158A (ja) 2024-11-19
JP2024543158A5 JP2024543158A5 (https=) 2024-12-02

Family

ID=86538655

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JP2024531308A Withdrawn JP2024543158A (ja) 2021-11-24 2021-11-24 多重特異性リガンド結合分子及びその用途

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US (1) US20250002557A1 (https=)
EP (1) EP4438629A1 (https=)
JP (1) JP2024543158A (https=)
WO (1) WO2023092324A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116162148B (zh) * 2021-11-24 2025-09-09 中山光度生物医药有限公司 多特异性配体结合分子及其应用
CN120536440A (zh) * 2025-05-23 2025-08-26 中山大学中山眼科中心 一种靶向pdgf-c抑制纤维化的核酸适配子及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
ATE135397T1 (de) 1988-09-23 1996-03-15 Cetus Oncology Corp Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
CN101433715B (zh) 1999-06-08 2013-04-17 里珍纳龙药品有限公司 具有改善的药物动力学特性的修饰嵌合多肽
WO2015123715A1 (en) 2014-02-21 2015-08-27 Vegenics Pty Limited Ligand binding molecules and uses thereof

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Publication number Publication date
US20250002557A1 (en) 2025-01-02
EP4438629A1 (en) 2024-10-02
WO2023092324A1 (zh) 2023-06-01

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