JP2024539087A5 - - Google Patents
Info
- Publication number
- JP2024539087A5 JP2024539087A5 JP2024523400A JP2024523400A JP2024539087A5 JP 2024539087 A5 JP2024539087 A5 JP 2024539087A5 JP 2024523400 A JP2024523400 A JP 2024523400A JP 2024523400 A JP2024523400 A JP 2024523400A JP 2024539087 A5 JP2024539087 A5 JP 2024539087A5
- Authority
- JP
- Japan
- Prior art keywords
- molecule
- uridine
- molecule according
- modified
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2021078830 | 2021-10-18 | ||
| EPPCT/EP2021/078830 | 2021-10-18 | ||
| PCT/EP2022/078870 WO2023066875A1 (en) | 2021-10-18 | 2022-10-17 | Modified replicable rna and related compositions and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024539087A JP2024539087A (ja) | 2024-10-28 |
| JP2024539087A5 true JP2024539087A5 (https=) | 2025-10-20 |
Family
ID=78483248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523400A Pending JP2024539087A (ja) | 2021-10-18 | 2022-10-17 | 修飾複製可能ｒｎａおよび関連組成物ならびにそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250236883A1 (https=) |
| EP (1) | EP4419695A1 (https=) |
| JP (1) | JP2024539087A (https=) |
| CN (1) | CN118103516A (https=) |
| AU (1) | AU2022369342A1 (https=) |
| CA (1) | CA3234396A1 (https=) |
| WO (1) | WO2023066875A1 (https=) |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008119827A1 (en) | 2007-04-02 | 2008-10-09 | Fit Biotech Oy | Transreplicase constructs |
| CN104072561B (zh) | 2007-06-19 | 2017-12-22 | 路易斯安那州州立大学及农业机械学院管理委员会 | 信使rna帽的抗‑反向硫代磷酸类似物的合成和用途 |
| ES2840725T3 (es) | 2007-08-20 | 2021-07-07 | Glaxo Group Ltd | Procedimiento de producción |
| PL215513B1 (pl) | 2008-06-06 | 2013-12-31 | Univ Warszawski | Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka |
| DE102008061522A1 (de) | 2008-12-10 | 2010-06-17 | Biontech Ag | Verwendung von Flt3-Ligand zur Verstärkung von Immunreaktionen bei RNA-Immunisierung |
| EP2281579A1 (en) | 2009-08-05 | 2011-02-09 | BioNTech AG | Vaccine composition comprising 5'-Cap modified RNA |
| NZ606591A (en) | 2010-07-06 | 2015-02-27 | Novartis Ag | Cationic oil-in-water emulsions |
| ES2557382T3 (es) | 2010-07-06 | 2016-01-25 | Glaxosmithkline Biologicals Sa | Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN |
| MX2013002332A (es) | 2010-08-31 | 2013-03-18 | Novartis Ag | Lipidos apropiados para suministro liposomal del arn que codifica la proteina. |
| SI4043040T1 (sl) | 2010-08-31 | 2023-04-28 | Glaxosmithkline Biologicals Sa | Mali liposomi za dostavo imunogen-kodirajoče RNA |
| LT4226941T (lt) | 2010-08-31 | 2025-01-10 | Glaxosmithkline Biologicals Sa | Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| JP6059220B2 (ja) | 2011-07-06 | 2017-01-18 | ノバルティス アーゲー | 核酸を含む水中油型エマルジョン |
| MX350258B (es) | 2011-07-06 | 2017-08-31 | Novartis Ag | Emulsiones cationicas de aceite en agua. |
| MX366055B (es) | 2011-08-31 | 2019-06-26 | Novartis Ag | Liposomas pegilados para admistracion de acido ribonucleico (arn) que codifica para inmunogeno. |
| WO2013143555A1 (en) | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| WO2014071963A1 (en) | 2012-11-09 | 2014-05-15 | Biontech Ag | Method for cellular rna expression |
| WO2016005004A1 (en) | 2014-07-11 | 2016-01-14 | Biontech Rna Pharmaceuticals Gmbh | Stabilization of poly(a) sequence encoding dna sequences |
| WO2017162266A1 (en) | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Rna replicon for versatile and efficient gene expression |
| US20220054611A1 (en) * | 2018-12-17 | 2022-02-24 | Immune Design Corp. | Pathogen-associated molecular pattern molecules and rna immunogenic compositions and methods of using the compositions for treating cancer |
| WO2020144295A1 (en) * | 2019-01-10 | 2020-07-16 | Biontech Rna Pharmaceuticals Gmbh | Localized administration of rna molecules for therapy |
-
2022
- 2022-10-17 EP EP22805814.5A patent/EP4419695A1/en active Pending
- 2022-10-17 WO PCT/EP2022/078870 patent/WO2023066875A1/en not_active Ceased
- 2022-10-17 CN CN202280068980.1A patent/CN118103516A/zh active Pending
- 2022-10-17 AU AU2022369342A patent/AU2022369342A1/en active Pending
- 2022-10-17 CA CA3234396A patent/CA3234396A1/en active Pending
- 2022-10-17 US US18/697,945 patent/US20250236883A1/en active Pending
- 2022-10-17 JP JP2024523400A patent/JP2024539087A/ja active Pending
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