JP2024535766A5 - - Google Patents
Info
- Publication number
- JP2024535766A5 JP2024535766A5 JP2024515310A JP2024515310A JP2024535766A5 JP 2024535766 A5 JP2024535766 A5 JP 2024535766A5 JP 2024515310 A JP2024515310 A JP 2024515310A JP 2024515310 A JP2024515310 A JP 2024515310A JP 2024535766 A5 JP2024535766 A5 JP 2024535766A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- particles
- lipid
- phospho
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2021074976 | 2021-09-10 | ||
| EPPCT/EP2021/074976 | 2021-09-10 | ||
| PCT/EP2022/075168 WO2023036960A1 (en) | 2021-09-10 | 2022-09-09 | Lipid-based rna formulations suitable for therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024535766A JP2024535766A (ja) | 2024-10-02 |
| JP2024535766A5 true JP2024535766A5 (enExample) | 2025-09-18 |
Family
ID=83594138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024515310A Pending JP2024535766A (ja) | 2021-09-10 | 2022-09-09 | 治療に適した脂質ベースのrna製剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240408032A1 (enExample) |
| EP (1) | EP4398882A1 (enExample) |
| JP (1) | JP2024535766A (enExample) |
| CN (1) | CN118265522A (enExample) |
| WO (1) | WO2023036960A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022115645A1 (en) | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
| AU2023413766A1 (en) | 2022-12-23 | 2025-05-29 | Biontech Delivery Technologies Gmbh | Composition |
| WO2024193827A1 (en) * | 2023-03-23 | 2024-09-26 | BioNTech SE | Stabilized nucleic acid compositions and methods for preparing, storing and using the same |
| WO2025021277A1 (en) * | 2023-07-21 | 2025-01-30 | BioNTech SE | Agents and methods for targeted delivery of cytokines to immune cells |
| CN118001254B (zh) * | 2024-04-09 | 2024-07-26 | 北京悦康科创医药科技股份有限公司 | 靶向抗原呈递细胞的脂质组合物及其应用 |
| WO2026017917A1 (en) * | 2024-07-19 | 2026-01-22 | Ethris Gmbh | Rnas with reduced ribosomal frameshift expression products |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| EP2186528B1 (en) * | 2007-08-06 | 2014-03-19 | Senju Pharmaceutical Co., Ltd. | Pharmaceutical containing hif-1 alpha and hif-2 alpha expression inhibitor |
| CN107028886A (zh) * | 2009-11-04 | 2017-08-11 | 不列颠哥伦比亚大学 | 含有核酸的脂质粒子及相关的方法 |
| WO2016005004A1 (en) | 2014-07-11 | 2016-01-14 | Biontech Rna Pharmaceuticals Gmbh | Stabilization of poly(a) sequence encoding dna sequences |
| SI3445850T1 (sl) | 2016-04-22 | 2021-12-31 | BioNTech SE | Postopki za zagotavljanje enoverižne RNA |
| WO2022115645A1 (en) * | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
-
2022
- 2022-09-09 EP EP22785696.0A patent/EP4398882A1/en active Pending
- 2022-09-09 WO PCT/EP2022/075168 patent/WO2023036960A1/en not_active Ceased
- 2022-09-09 CN CN202280074040.3A patent/CN118265522A/zh active Pending
- 2022-09-09 JP JP2024515310A patent/JP2024535766A/ja active Pending
- 2022-09-09 US US18/689,727 patent/US20240408032A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024535766A5 (enExample) | ||
| US12453739B2 (en) | Synergistic enhancement of the delivery of nucleic acids via blended formulations | |
| JP7236525B2 (ja) | CFTR mRNA組成物ならびに関連する方法及び使用 | |
| US20220411791A1 (en) | Nuclease Resistant Polynucleotides and Uses Thereof | |
| EP3628335B1 (en) | Lipidic nanoparticles for mrna delivery in the lungs | |
| US12070509B2 (en) | Nucleic acids and methods of treatment for cystic fibrosis | |
| JP6463810B2 (ja) | mRNA送達のための脂質ナノ粒子組成物および方法 | |
| JP2024533865A5 (enExample) | ||
| JP7774615B2 (ja) | 大型rnaの脂質ナノ粒子封入 | |
| US20140294940A1 (en) | Mrna therapy for urea cycle disorders | |
| US12564645B2 (en) | Methods for treatment of methylmalonic acidemia | |
| JP2011507534A5 (enExample) | ||
| JP7789103B2 (ja) | 原発性線毛機能不全症の治療のための組成物および方法 | |
| AU2022381750A1 (en) | Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis | |
| JP2025501764A5 (enExample) | ||
| CN113908288A (zh) | 一种mRNA递送系统及其制备方法和应用 | |
| JP2025501905A (ja) | イオン化脂質、脂質ナノ粒子、及びこれらの使用 | |
| KR20240066978A (ko) | 핵산 약물의 경폐전달을 위한 지질나노입자 제형 및 이의 활용 |