JP2024533848A5 - - Google Patents

Info

Publication number
JP2024533848A5
JP2024533848A5 JP2024520962A JP2024520962A JP2024533848A5 JP 2024533848 A5 JP2024533848 A5 JP 2024533848A5 JP 2024520962 A JP2024520962 A JP 2024520962A JP 2024520962 A JP2024520962 A JP 2024520962A JP 2024533848 A5 JP2024533848 A5 JP 2024533848A5
Authority
JP
Japan
Prior art keywords
fragment
c4bpβ
antibody
amino acid
chimeric construct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024520962A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024533848A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/077847 external-priority patent/WO2023057588A1/en
Publication of JP2024533848A publication Critical patent/JP2024533848A/ja
Publication of JP2024533848A5 publication Critical patent/JP2024533848A5/ja
Pending legal-status Critical Current

Links

JP2024520962A 2021-10-06 2022-10-06 炎症組織へのターゲティング特異性を備えるインターロイキン2キメラコンストラクト Pending JP2024533848A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21306399 2021-10-06
EP21306399.3 2021-10-06
PCT/EP2022/077847 WO2023057588A1 (en) 2021-10-06 2022-10-06 Interleukin 2 chimeric constructs with targeting specificy to inflamed tissues

Publications (2)

Publication Number Publication Date
JP2024533848A JP2024533848A (ja) 2024-09-12
JP2024533848A5 true JP2024533848A5 (cg-RX-API-DMAC7.html) 2025-10-20

Family

ID=78463430

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024520962A Pending JP2024533848A (ja) 2021-10-06 2022-10-06 炎症組織へのターゲティング特異性を備えるインターロイキン2キメラコンストラクト

Country Status (11)

Country Link
US (1) US20240376172A1 (cg-RX-API-DMAC7.html)
EP (1) EP4412631A1 (cg-RX-API-DMAC7.html)
JP (1) JP2024533848A (cg-RX-API-DMAC7.html)
KR (1) KR20240113459A (cg-RX-API-DMAC7.html)
CN (1) CN118414160A (cg-RX-API-DMAC7.html)
AU (1) AU2022360645A1 (cg-RX-API-DMAC7.html)
CA (1) CA3233644A1 (cg-RX-API-DMAC7.html)
IL (1) IL311883A (cg-RX-API-DMAC7.html)
MX (1) MX2024004291A (cg-RX-API-DMAC7.html)
WO (1) WO2023057588A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202402730B (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024194686A2 (en) * 2023-03-17 2024-09-26 Oxitope Pharma B.V. Anti-phosphocholine antibodies and methods of use thereof
WO2024194685A2 (en) * 2023-03-17 2024-09-26 Oxitope Pharma B.V. Anti-phosphocholine antibodies and methods of use thereof
WO2026159300A1 (en) 2025-01-24 2026-07-30 Iltoo Pharma M3c65 antibody and derivatives thereof for targeting inflammation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341562C (en) 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell
FI82266C (fi) 1982-10-19 1991-02-11 Cetus Corp Foerfarande foer framstaellning av il-2 -mutein.
WO1985000817A1 (en) 1983-08-10 1985-02-28 Amgen Microbial expression of interleukin ii
CA1340265C (en) 1985-01-18 1998-12-15 Kirston E. Koths Oxidation resistant muteins
US4752585A (en) 1985-12-17 1988-06-21 Cetus Corporation Oxidation-resistant muteins
DZ2788A1 (fr) 1998-05-15 2003-12-01 Bayer Ag Agonistes et antagonistes selectifs à IL-2.
FR2869323B1 (fr) 2004-04-22 2006-07-21 Univ Reims Champagne Ardenne Utilisation du gene codant la chaine beta de la proteine c4bp dans la production de proteines dimeriques recombinantes
DE102008023820A1 (de) 2008-05-08 2009-11-12 Aicuris Gmbh & Co. Kg Mittel zur Behandlung und/oder Prophylaxe einer Autoimmunerkrankung und zur Bildung von Regulatorischen T-Zellen
WO2010085495A1 (en) 2009-01-21 2010-07-29 Amgen Inc. Compositions and methods of treating inflammatory and autoimmune diseases
US8437577B2 (en) 2009-03-05 2013-05-07 Tektronix, Inc. Methods and systems for image registration
WO2011160845A2 (en) * 2010-06-24 2011-12-29 Medirista Biotechnologies Ab Oxidized phospholipids and lipoproteins, and antibodies thereto, as biomarkers of inflammatory conditions and methods of treatment
US9580486B2 (en) 2013-03-14 2017-02-28 Amgen Inc. Interleukin-2 muteins for the expansion of T-regulatory cells
PT3102595T (pt) * 2014-02-06 2019-01-11 Hoffmann La Roche Proteínas de fusão de interleucina-2 e suas utilizações
KR102493543B1 (ko) 2014-07-21 2023-01-30 데리니아, 인크. 자가면역 질환의 치료를 위한 조절 t 세포를 선택적으로 활성화시키는 분자
IL304950A (en) 2015-04-10 2023-10-01 Amgen Inc Interleukin for the expansion of myotonic control T-2 cells
ES2982752T3 (es) 2015-10-22 2024-10-17 Iltoo Pharma Composiciones farmacéuticas de il-2
WO2019148204A1 (en) * 2018-01-29 2019-08-01 The Regents Of The University Of California Therapies and methods to treat tlr2-mediated diseases and disorders
WO2020252421A2 (en) * 2019-06-14 2020-12-17 Cugene, Inc. Novel interleukin-2 variants and bifunctional fusion molecules thereof
US20230036793A1 (en) * 2019-12-12 2023-02-02 Iltoo Pharma Interleukin 2 chimeric constructs

Similar Documents

Publication Publication Date Title
JP6694409B2 (ja) Tnfsf一本鎖分子
JP6181145B2 (ja) 改善された特異性を有する新規免疫グロブリン結合タンパク質
JP7323949B2 (ja) フラジェリン融合タンパク質及びその使用
EP3998077B1 (en) Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
Mertens Tribodies: fab–scfv fusion proteins as a platform to create multifunctional pharmaceuticals
CN103987728B (zh) 抗癌融合蛋白
JP2023504914A5 (cg-RX-API-DMAC7.html)
CN107108737B (zh) c-met特异性人抗体及其制备方法
FI3368555T3 (fi) Kaksitoimisia proteiineja ja niitä sisältävä farmaseuttinen koostumus
JP2023553697A5 (cg-RX-API-DMAC7.html)
CN105473609A (zh) 用于表达肽和蛋白的方法
EP3344647B1 (en) Coiled-coil connector
CN106380517B (zh) 一种对中东呼吸综合征冠状病毒具有中和活性的小分子抗体及其应用
JP2009507503A5 (cg-RX-API-DMAC7.html)
Eisenmesser et al. Expression, purification, refolding, and characterization of recombinant human interleukin-13: utilization of intracellular processing
CN120590542A (zh) 基于clec9a的嵌合蛋白复合物
CN103562220A (zh) 抗癌融合蛋白
Orrapin et al. Recombinant expression of novel protegrin-1 dimer and LL-37-linker–histatin-5 hybrid peptide mediated biotin carboxyl carrier protein fusion partner
KR20190109947A (ko) 재조합 인간 혈청 알부민의 수용성 과발현 및 정제 방법
CN100427506C (zh) 从融合多肽制备感兴趣的多肽的方法
CN101265291A (zh) 一种重组猪源抗菌肽pg4及其生物合成方法与应用
JP2023550191A5 (cg-RX-API-DMAC7.html)
JP2025036661A (ja) 抗体酵素の革新的製造技術
WO2023078436A1 (en) Fusion proteins comprising 072 core peptide and use thereof
US8470971B2 (en) Cell permeable p53 recombinant protein, polynucleotide encoding the same, and anti-cancer composition containing the same as active ingredient